Publications by authors named "Gritta Janka"

74Publications

Treatment and Mortality of Hemophagocytic Lymphohistiocytosis in Adult Critically Ill Patients: A Systematic Review With Pooled Analysis.

Crit Care Med 2020 Nov;48(11):e1137-e1146

Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1097/CCM.0000000000004581DOI Listing
November 2020

Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore.

Crit Care 2020 05 24;24(1):244. Epub 2020 May 24.

Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1186/s13054-020-02941-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245825PMC
May 2020

Hyperferritinemia in Critically Ill Patients.

Crit Care Med 2020 Apr;48(4):459-465

Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, D-13353 Berlin, Germany.

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http://dx.doi.org/10.1097/CCM.0000000000004131DOI Listing
April 2020

Hemophagocytic lymphohistiocytosis in adults: collaborative analysis of 137 cases of a nationwide German registry.

J Cancer Res Clin Oncol 2020 Apr 20;146(4):1065-1077. Epub 2020 Feb 20.

Klinik für Innere Medizin II, Hämatologie, Onkologie, Immunologie, Infektiologie und Palliativmedizin, Schwarzwald-Baar Klinikum, Klinikstr. 11, 78052, Villingen-Schwenningen, Germany.

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http://dx.doi.org/10.1007/s00432-020-03139-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085479PMC
April 2020

Hemophagocytic Lymphohistiocytosis in Critically Ill Patients.

Shock 2020 06;53(6):701-709

Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, Berlin, Germany.

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http://dx.doi.org/10.1097/SHK.0000000000001454DOI Listing
June 2020

Recommendations for the management of hemophagocytic lymphohistiocytosis in adults.

Blood 2019 06 16;133(23):2465-2477. Epub 2019 Apr 16.

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institute, and Theme of Children's and Women's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1182/blood.2018894618DOI Listing
June 2019

Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society.

J Allergy Clin Immunol Pract 2018 Sep - Oct;6(5):1508-1517. Epub 2018 Jul 4.

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Theme of Children's and Women's Health, Karolinska University Hospital Solna, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183038
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http://dx.doi.org/10.1016/j.jaip.2018.05.031DOI Listing
November 2019

Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease.

Pediatr Blood Cancer 2018 11 1;65(11):e27344. Epub 2018 Aug 1.

Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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http://dx.doi.org/10.1002/pbc.27344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168068PMC
November 2018

Effective Immunological Guidance of Genetic Analyses Including Exome Sequencing in Patients Evaluated for Hemophagocytic Lymphohistiocytosis.

J Clin Immunol 2017 Nov 21;37(8):770-780. Epub 2017 Sep 21.

Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1007/s10875-017-0443-1DOI Listing
November 2017

Similar but not the same: Differential diagnosis of HLH and sepsis.

Crit Rev Oncol Hematol 2017 Jun 23;114:1-12. Epub 2017 Mar 23.

Department of Hematology, Oncology and Internal Diseases, Medical University of Warsaw, ul. Banacha 1a, 02-097 Warsaw, Poland.

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http://dx.doi.org/10.1016/j.critrevonc.2017.03.023DOI Listing
June 2017

How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?

Curr Treat Options Neurol 2017 Jan;19(1)

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s11940-017-0439-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290057PMC
January 2017

Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire.

Eur J Immunol 2017 02 3;47(2):364-373. Epub 2017 Jan 3.

Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

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http://doi.wiley.com/10.1002/eji.201646686
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http://dx.doi.org/10.1002/eji.201646686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163530PMC
February 2017

Your critical care patient may have HLH (hemophagocytic lymphohistiocytosis).

Crit Care 2016 Jul 6;20(1):215. Epub 2016 Jul 6.

Department of Hematology, Oncology and Internal Diseases, Medical University of Warsaw, ul. Banacha 1a, 02-097, Warsaw, Poland.

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http://dx.doi.org/10.1186/s13054-016-1369-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937543PMC
July 2016

Late-onset hemophagocytic lymphohistiocytosis (HLH) in an adult female with Griscelli syndrome type 2 (GS2).

Ann Hematol 2015 Jun 30;94(6):1057-60. Epub 2014 Dec 30.

Department of Hematology and Oncology, Schwarzwald-Baar Clinic, Academic Teaching Hospital University of Freiburg, Klinikstr. 11, 78052, Villingen-Schwenningen, Germany,

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http://dx.doi.org/10.1007/s00277-014-2284-9DOI Listing
June 2015

Hemophagocytic syndromes--an update.

Blood Rev 2014 Jul 22;28(4):135-42. Epub 2014 Mar 22.

Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.blre.2014.03.002DOI Listing
July 2014

Determination of an appropriate cut-off value for ferritin in the diagnosis of hemophagocytic lymphohistiocytosis.

Pediatr Blood Cancer 2014 Nov 21;61(11):2101-3. Epub 2014 Apr 21.

Pediatric Hematology and Oncology, University Hospital Medical Center, Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.25058DOI Listing
November 2014

Hemophagocytic lymphohistiocytosis: pathogenesis and treatment.

Hematology Am Soc Hematol Educ Program 2013 ;2013:605-11

1University Medical Center Eppendorf, Hamburg, Germany.

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http://www.asheducationbook.org/cgi/doi/10.1182/asheducation
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http://dx.doi.org/10.1182/asheducation-2013.1.605DOI Listing
July 2014

Differentiating macrophage activation syndrome in systemic juvenile idiopathic arthritis from other forms of hemophagocytic lymphohistiocytosis.

J Pediatr 2013 Jun 17;162(6):1245-51. Epub 2013 Jan 17.

Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Germany.

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http://dx.doi.org/10.1016/j.jpeds.2012.11.081DOI Listing
June 2013

Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease.

Blood 2013 Jan 27;121(4):604-13. Epub 2012 Nov 27.

Institute for Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-07-44
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http://dx.doi.org/10.1182/blood-2012-07-441139DOI Listing
January 2013

Administration of recombinant erythropoietin alone does not improve the phenotype in iron refractory iron deficiency anemia patients.

Ann Hematol 2013 Mar 20;92(3):387-94. Epub 2012 Nov 20.

Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00277-012-1618-8DOI Listing
March 2013

Parental informed consent in pediatric cancer trials: a population-based survey in Germany.

Pediatr Blood Cancer 2013 Mar 26;60(3):446-50. Epub 2012 Sep 26.

University of Hamburg, Research Centre for Biotechnology, Society and the Environment, 22529 Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.24330DOI Listing
March 2013

Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis.

Arthritis Res Ther 2012 Jun 8;14(3):213. Epub 2012 Jun 8.

Centre of Chronic Immunodeficiency, University Medical Center Freiburg, D-79106 Freiburg, Germany.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar3843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446494PMC
June 2012

Risk factors for early death in children with haemophagocytic lymphohistiocytosis.

Acta Paediatr 2012 Mar 17;101(3):313-8. Epub 2011 Nov 17.

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://doi.wiley.com/10.1111/j.1651-2227.2011.02501.x
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http://dx.doi.org/10.1111/j.1651-2227.2011.02501.xDOI Listing
March 2012

Pancreatic exocrine function and cardiac iron in patients with iron overload and with thalassemia.

Pediatr Blood Cancer 2011 Oct 10;57(4):674-6. Epub 2011 Jun 10.

University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.22990DOI Listing
October 2011

Distribution of cardiac iron measured by magnetic resonance imaging (MRI)-R*2.

J Magn Reson Imaging 2010 Nov;32(5):1104-9

University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/jmri.22364DOI Listing
November 2010

An aggressive systemic juvenile xanthogranuloma clonally related to a preceding T-cell acute lymphoblastic leukemia.

Pediatr Blood Cancer 2011 May 16;56(5):859-62. Epub 2010 Sep 16.

HELIOS Klinikum Krefeld, Zentrum für Kinder- und Jugendmedizin, Lutherplatz 40, 47805 Krefeld, Germany.

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http://dx.doi.org/10.1002/pbc.22756DOI Listing
May 2011

Neonatal cholestasis and glucose-6-P-dehydrogenase deficiency.

Pediatr Blood Cancer 2010 May;54(5):758-60

Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.22390DOI Listing
May 2010

Hemophagocytic lymphohistiocytosis and Kawasaki disease: combined manifestation and differential diagnosis.

Pediatr Blood Cancer 2009 Sep;53(3):493-5

Institute of Pathology, University of Rostock, Rostock, Germany.

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http://doi.wiley.com/10.1002/pbc.22098
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http://dx.doi.org/10.1002/pbc.22098DOI Listing
September 2009

Pancytopenia in a 4-year-old boy. 22q11.2 microdeletion syndrome.

Acta Paediatr 2009 May;98(5):769-70, 912-4

Department of Haematology and Oncology, Children's Hospital, University of Hamburg, Germany.

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http://dx.doi.org/10.1111/j.1651-2227.2009.00920.xDOI Listing
May 2009

Infection of T lymphocytes in Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children of non-Asian origin.

Pediatr Blood Cancer 2009 Aug;53(2):184-90

Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://doi.wiley.com/10.1002/pbc.22037
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http://dx.doi.org/10.1002/pbc.22037DOI Listing
August 2009

Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis.

Br J Haematol 2008 Feb 10;140(3):327-35. Epub 2007 Dec 10.

Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06922.xDOI Listing
February 2008

Impact of reduction of therapy on infectious complications in childhood acute lymphoblastic leukemia.

Pediatr Blood Cancer 2008 Feb;50(2):259-63

University Children's Hospital, Department of Hematology and Oncology, Munich, Germany.

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http://dx.doi.org/10.1002/pbc.21298DOI Listing
February 2008

Hemophagocytic syndromes.

Authors:
Gritta E Janka

Blood Rev 2007 Sep 21;21(5):245-53. Epub 2007 Jun 21.

Department of Hematology and Oncology, Children's Hospital, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.blre.2007.05.001DOI Listing
September 2007

Familial and acquired hemophagocytic lymphohistiocytosis.

Authors:
Gritta E Janka

Eur J Pediatr 2007 Feb 7;166(2):95-109. Epub 2006 Dec 7.

Department of Hematology and Oncology, Children's Hospital, University of Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00431-006-0258-1DOI Listing
February 2007

HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.

Pediatr Blood Cancer 2007 Feb;48(2):124-31

Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://www.ourmayagirl.com/resources/HLH_2004_diagnosis_and_
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http://dx.doi.org/10.1002/pbc.21039DOI Listing
February 2007

Non-transferrin-bound iron during blood transfusion cycles in beta-thalassemia major.

Ann N Y Acad Sci 2005 ;1054:429-32

University Medical Center Hamburg-Eppendorf, Department of Pediatric Hematology/Oncology, Martinistr. 52, Hamburg D-20246, Germany.

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http://dx.doi.org/10.1196/annals.1345.074DOI Listing
July 2006

Familial and acquired hemophagocytic lymphohistiocytosis.

Hematology Am Soc Hematol Educ Program 2005 :82-8

Children's University Hospital, Hematology & Oncology, Martinistr. 52, Hamburg 20246, Germany.

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http://link.springer.com/content/pdf/10.1007/s00431-006-0258
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http://www.asheducationbook.org/cgi/doi/10.1182/asheducation
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http://dx.doi.org/10.1182/asheducation-2005.1.82DOI Listing
November 2009

Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A.

Hum Mutat 2006 Jan;27(1):62-8

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/humu.20274DOI Listing
January 2006

Subtyping of natural killer cell cytotoxicity deficiencies in haemophagocytic lymphohistocytosis provides therapeutic guidance.

Br J Haematol 2005 Jun;129(5):658-66

Childhood Cancer Research Unit, Department of Paediatric Haematology and Oncology, Karolinska Hospital, Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1365-2141.2005.05502.xDOI Listing
June 2005

Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis.

Br J Haematol 2005 Jun;129(5):622-30

Childhood Cancer Research Unit, Institution for Woman and Child Health, Karolinska Institutet, Department of Paediatric Haematology and Oncology, Karolinska Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1365-2141.2005.05501.xDOI Listing
June 2005

Modern management of children with haemophagocytic lymphohistiocytosis.

Br J Haematol 2004 Jan;124(1):4-14

Department of Haematology and Oncology, Children's Hospital, University of Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04726.xDOI Listing
January 2004

Rapid LightCycler assay for identification of the perforin codon 374 Trp --> stop mutation in patients and families with hemophagocytic lymphohistiocytosis (HLH).

Med Pediatr Oncol 2003 Jul;41(1):26-9

Department of Pediatric Hematology and Oncology, University Children's Hospital, Hamburg, Germany.

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http://dx.doi.org/10.1002/mpo.10310DOI Listing
July 2003

Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.

Hum Genet 2003 Jan 11;112(1):98-9. Epub 2002 Oct 11.

Childhood Cancer Research Unit, Department of Woman and Child Health, Karoliniska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00439-002-0841-0DOI Listing
January 2003