Publications by authors named "Gretchen Poortinga"

24Publications

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.

PLoS Negl Trop Dis 2017 03 6;11(3):e0005432. Epub 2017 Mar 6.

Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0005432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354456PMC
March 2017

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma.

Cancer Discov 2016 Jan 21;6(1):59-70. Epub 2015 Oct 21.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia. Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, Australia. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0673DOI Listing
January 2016

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila.

Cell Signal 2015 Oct 26;27(10):2045-53. Epub 2015 Jul 26.

Department of Anatomy and Neuroscience, The University of Melbourne, Parkville 3010, Melbourne Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2015.07.018DOI Listing
October 2015

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models.

Nat Commun 2015 Jun 15;6:7404. Epub 2015 Jun 15.

Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Melbourne 3010, Australia.

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http://dx.doi.org/10.1038/ncomms8404DOI Listing
June 2015

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes.

Genome Res 2015 Feb 1;25(2):201-12. Epub 2014 Dec 1.

Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia; Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; School of Biomedical Sciences, University of Queensland, Brisbane 4072, Queensland, Australia

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http://dx.doi.org/10.1101/gr.176115.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315294PMC
February 2015

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation.

Blood 2008 Sep 11;112(6):2305-17. Epub 2008 Jul 11.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://dx.doi.org/10.1182/blood-2007-09-111856DOI Listing
September 2008