Publications by authors named "Gregory S Schultz"

99Publications

Cadexomer iodine effectively reduces bacterial biofilm in porcine wounds ex vivo and in vivo.

Int Wound J 2019 Jun 13;16(3):674-683. Epub 2019 Mar 13.

Department of Obstetrics and Gynecology, Institute for Wound Research, University of Florida, Gainesville, Florida.

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June 2019

Implementing TIMERS: the race against hard-to-heal wounds.

J Wound Care 2019 03;23(Sup3a):S1-S50

Associate Chief Medical Officer, MiMedx, Georgia. Adjunct Assistant Professor, Duke University School of Medicine, Durham, North Carolina. Medical Director of Wound Care and Infection Prevention, Landmark Hospital, Salt Lake City, Utah, US.

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March 2019

Assessment of Topical Therapies for Improving the Optical Clarity Following Stromal Wounding in a Novel Ex Vivo Canine Cornea Model.

Invest Ophthalmol Vis Sci 2018 11;59(13):5509-5521

Department of Small Animal Clinical Sciences, University of Florida, Gainesville, Florida, United States.

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November 2018

A Surfactant-Based Dressing to Treat and Prevent Acinetobacter baumannii Biofilms.

J Burn Care Res 2018 08;39(5):766-770

University of Florida, Institute for Wound Research, Gainesville, FL.

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August 2018

Knockdown of the Herpes Simplex Virus 1 Latency-Associated Transcript Reduces Reactivation from Latency.

J Virol 2018 08 31;92(16). Epub 2018 Jul 31.

Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, Florida, USA

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August 2018

Effectiveness of a monofilament wound debridement pad at removing biofilm and slough: ex vivo and clinical performance.

J Wound Care 2018 02;27(2):80-90

The Institute for Wound Research at the University of Florida, Department of Obstetrics & Gynecology, University of Florida, Gainesville, FL, US.

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February 2018

Dual-Phase Iontophoresis for the Delivery of Antisense Oligonucleotides.

Nucleic Acid Ther 2017 Aug 4;27(4):238-250. Epub 2017 Apr 4.

1 Institute for Wound Research, University of Florida , Gainesville, Florida.

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August 2017

Connective tissue growth factor is not necessary for haze formation in excimer laser wounded mouse corneas.

PLoS One 2017 16;12(2):e0172304. Epub 2017 Feb 16.

Institute of Wound Research, University of Florida, Gainesville, Florida, United States of America.

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August 2017

Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria.

Int J Antimicrob Agents 2017 Feb 6;49(2):247-251. Epub 2016 Dec 6.

Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA. Electronic address:

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February 2017

Testing the influence of surfactant-based wound dressings on proteinase activity.

Int Wound J 2017 Oct 8;14(5):786-790. Epub 2016 Dec 8.

The Institute for Wound Research at the University of Florida, Department of OB/GYN, University of Florida, Gainesville, FL, USA.

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October 2017

Adeno-associated Virus Vectors Efficiently Transduce Mouse and Rabbit Sensory Neurons Coinfected with Herpes Simplex Virus 1 following Peripheral Inoculation.

J Virol 2016 09 12;90(17):7894-901. Epub 2016 Aug 12.

Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, Florida, USA

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September 2016

A surfactant-based wound dressing can reduce bacterial biofilms in a porcine skin explant model.

Int Wound J 2017 Apr 22;14(2):408-413. Epub 2016 May 22.

The Institute for Wound Research at the University of Florida, Department of Obstetrics & Gynecology, University of Florida, Gainesville, FL, USA.

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April 2017

Evaluation of a bilayered, micropatterned hydrogel dressing for full-thickness wound healing.

Exp Biol Med (Maywood) 2016 05 31;241(9):986-95. Epub 2016 Mar 31.

Sharklet Technologies, Inc., Aurora, CO 80045, USA Saisijin Biotech, LLC, Orlando, FL 32827, USA J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.

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May 2016

Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model.

PLoS One 2015 22;10(9):e0138054. Epub 2015 Sep 22.

Department of Ophthalmology, COM, University of Florida, 1600 SW Archer Rd., Gainesville, FL, 32610, United States of America.

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May 2016

Medical Honey and Silver Dressings Do Not Interfere with Each Other's Key Functional Attributes.

Wounds 2014 Nov;26(11):309-16

University of Florida, Department of OB/GYN, The Institute for Wound Research, Gainesville, FL.

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November 2014

Chronic wounds with emphasis in diabetic foot ulcers.

Biomed Res Int 2014 17;2014:890352. Epub 2014 Mar 17.

Center for Genetic Engineering and Biotechnology, P.O. Box 6162, 10600 Havana, Cuba.

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December 2014

Conditional knockout of CTGF affects corneal wound healing.

Invest Ophthalmol Vis Sci 2014 Apr 1;55(4):2062-70. Epub 2014 Apr 1.

Institute for Wound Research, University of Florida, Gainesville, Florida, United States.

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April 2014

Molecular Wound Assessments: Matrix Metalloproteinases.

Adv Wound Care (New Rochelle) 2013 Feb;2(1):18-23

Department of Obstetrics and Gynecology, Institute for Wound Research, University of Florida , Gainesville, Florida.

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February 2013

The effect of negative pressure wound therapy with periodic instillation using antimicrobial solutions on Pseudomonas aeruginosa biofilm on porcine skin explants.

Int Wound J 2013 Dec;10 Suppl 1:48-55

Institute of Wound Research, Department of Obstetrics and Gynecology, University of Florida, Gainesville, FL, USA.

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December 2013

A corneal scarring model.

Methods Mol Biol 2013 ;1037:277-98

Department of Obstetrics and Gynecology, Institute for Wound Research, University of Florida, Gainesville, FL, USA.

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July 2014

Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants.

Int Wound J 2015 Aug 13;12(4):469-83. Epub 2013 Sep 13.

Institute of Wound Research, Department of Obstetrics and Gynecology, College of Medicine, University of Florida, Gainesville, FL, USA.

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August 2015

Development of a novel ex vivo porcine skin explant model for the assessment of mature bacterial biofilms.

Wound Repair Regen 2013 Sep-Oct;21(5):704-14. Epub 2013 Aug 8.

Institute for Wound Research, Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida.

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May 2014

The progression of haze formation in rabbit corneas following phototherapeutic keratectomy.

Invest Ophthalmol Vis Sci 2013 Jul 16;54(7):4776-81. Epub 2013 Jul 16.

Institute of Wound Research, University of Florida, Gainesville, Florida 32610-0294, USA.

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July 2013

Glucose toxic effects on granulation tissue productive cells: the diabetics' impaired healing.

Biomed Res Int 2013 26;2013:256043. Epub 2012 Dec 26.

Tissue Repair and Cytoprotection Research Group, Center for Genetic Engineering and Biotechnology, Playa, CP 10600 Havana, Cuba.

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September 2013

Proteolytic processing of connective tissue growth factor in normal ocular tissues and during corneal wound healing.

Invest Ophthalmol Vis Sci 2012 Dec 13;53(13):8093-103. Epub 2012 Dec 13.

Department of Obstetrics and Gynecology, Institute for Wound Research, University of Florida, Gainesville, Florida 32610-0294, USA

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December 2012

Effect of connective tissue growth factor on protein kinase expression and activity in human corneal fibroblasts.

Invest Ophthalmol Vis Sci 2012 Dec 13;53(13):8076-85. Epub 2012 Dec 13.

Institute for Wound Research, University of Florida, Gainesville, Florida 32610-0294, USA.

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December 2012

Ectopic epithelial implants following surface ablation of the cornea.

Invest Ophthalmol Vis Sci 2012 Nov 21;53(12):7760-5. Epub 2012 Nov 21.

Institute for Wound Research, University of Florida, Gainesville, Florida 32610-0294, USA.

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November 2012

Comparison of single versus multiple injections of the protein saratin for prolonging bleb survival in a rabbit model.

Invest Ophthalmol Vis Sci 2012 Nov 19;53(12):7625-30. Epub 2012 Nov 19.

Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, USA.

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November 2012

Microbial barriers.

Clin Plast Surg 2012 Jul 22;39(3):229-38. Epub 2012 May 22.

Division of Plastic & Reconstructive Surgery, Department of Surgery, University of Florida, Post Office Box 100286, 1600 Southwest Archer Road, Gainesville, FL 32610, USA.

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July 2012

Molecular Mechanisms of Biofilm Infection: Biofilm Virulence Factors.

Adv Wound Care (New Rochelle) 2012 Jun;1(3):109-114

Department of Obstetrics and Gynecology, College of Medicine, Institute for Wound Research, University of Florida , Gainesville, Florida.

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June 2012

CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators.

FASEB J 2012 Aug 18;26(8):3365-79. Epub 2012 May 18.

Program in Stem Cell Biology and Regenerative Medicine, University of Florida, PO Box 100232, Gainesville, FL 32610, USA.

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August 2012

Prevention of ocular scarring post glaucoma filtration surgery using the inflammatory cell and platelet binding modulator saratin in a rabbit model.

PLoS One 2012 30;7(4):e35627. Epub 2012 Apr 30.

Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America.

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September 2012

A connective tissue growth factor signaling receptor in corneal fibroblasts.

Invest Ophthalmol Vis Sci 2012 Jun 5;53(7):3387-94. Epub 2012 Jun 5.

Institute for Wound Research, University of Florida, Gainesville, Florida 32610, USA.

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June 2012

Vorinostat: a potent agent to prevent and treat laser-induced corneal haze.

J Refract Surg 2012 Apr 1;28(4):285-90. Epub 2012 Mar 1.

Harry S. Truman Memorial Veterans' Hospital, Columbia, Missouri 65212, USA.

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April 2012

Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo.

PLoS One 2011 19;6(10):e26432. Epub 2011 Oct 19.

Harry S. Truman Memorial Veterans' Hospital, Columbia, Missouri, United States of America.

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February 2012

Time course of lesion development in the hairless guinea-pig model of sulfur mustard-induced dermal injury.

Wound Repair Regen 2011 May-Jun;19(3):348-57. Epub 2011 Mar 16.

CounterAct Research Center of Excellence, Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA.

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October 2011

Dynamic reciprocity in the wound microenvironment.

Wound Repair Regen 2011 Mar-Apr;19(2):134-48

Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida, USA.

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June 2011

Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study.

Otol Neurotol 2010 Apr;31(3):519-23

Department of Otolaryngology, University of Florida, 1600 SW Archer Rd., Gainesville, FL 32610-0264, U.S.A.

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April 2010

Interactions between extracellular matrix and growth factors in wound healing.

Wound Repair Regen 2009 Mar-Apr;17(2):153-62

Department of Obstetrics and Gynecology, University of Florida, Gainesville, 32610-0294, USA.

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August 2009

The pro-inflammatory environment in recalcitrant diabetic foot wounds.

Int Wound J 2008 Oct;5(4):530-9

Biomedical Research Direction, Pharmaceutical Division, Center for Genetic Engineering and Biotechnology, Avenida 31 e/158 y 190, Playa, PO Box 6162, Havana 10600, Cuba.

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October 2008

Arginine metabolites in wound fluids from pressure ulcers: a pilot study.

Biol Res Nurs 2008 Oct;10(2):87-92

VA Office of Academic Affiliation, North Florida/South Georgia Veterans Health System, Gainesville, FL 32608-1197, USA.

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October 2008

Wound dressing components degrade proteins detrimental to wound healing.

Int Wound J 2008 Oct 19;5(4):543-51. Epub 2008 Sep 19.

Department of Obstetrics and Gynecology, University of Florida, Gainesville, FL, USA.

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October 2008

Topical advances in wound care.

Gynecol Oncol 2008 Nov 14;111(2 Suppl):S70-80. Epub 2008 Sep 14.

Department of Surgery, Division of Surgical Oncology, Walter Reed Army Medical Center, Washington, D.C., USA.

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November 2008

Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA.

J Virol 2008 Aug 28;82(15):7467-74. Epub 2008 May 28.

Department of Molecular Genetics and Microbiology, Box 100266, University of Florida College of Medicine, Gainesville, FL 32610-0266, USA.

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August 2008

TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling.

Exp Cell Res 2008 Jan 7;314(1):131-42. Epub 2007 Sep 7.

Department of Pathology, Cells for Sight Transplantation and Research Programme, UCL Institute of Ophthalmology, 11-43 Bath Street, London, EC1V 9EL, UK.

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January 2008

Alteration of Smad3 signaling in ischemic rabbit dermal ulcer wounds.

Wound Repair Regen 2007 May-Jun;15(3):341-9

Division of Plastic and Reconstructive Surgery, Wound Healing Research Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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August 2007

TGF-beta- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling.

Am J Physiol Heart Circ Physiol 2007 Jul 16;293(1):H482-8. Epub 2007 Mar 16.

University of Florida College of Medicine, Gainesville, FL 32610-0286, USA.

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July 2007

Development of a microarray chip for gene expression in rabbit ocular research.

Mol Vis 2007 Feb 2;13:164-73. Epub 2007 Feb 2.

University of Florida's Interdisciplinary Center for Biotechnology Research, University of Florida, Gainsville, FL 32610-0294, USA.

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February 2007

Science and strategy for preventing and managing corneal ulceration.

Ocul Surf 2007 Jan;5(1):23-39

Department of Ophthalmology and the Department of Obstetrics and Gynecology, University of Florida, Gainesville, FL USA.

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January 2007

Alpha1-antitrypsin single dose adjuvant therapy for acute otitis media.

Otolaryngol Head Neck Surg 2006 Jul;135(1):111-5

Department of Otolaryngology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA.

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July 2006

Wound bed preparation and a brief history of TIME.

Int Wound J 2004 Apr;1(1):19-32

Department Obstetrics and Gynecology, University of Florida, gainesville, FL 32610-0294, USA.

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April 2004

Early differential MMP-2 and -9 dynamics during flow-induced arterial and vein graft adaptations.

J Surg Res 2006 Aug 20;134(2):327-34. Epub 2006 Feb 20.

Department of Surgery, University of Florida, Gainesville, Florida, USA.

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August 2006

Inflammatory proteases in chronic otitis externa.

Laryngoscope 2005 Apr;115(4):651-4

Department of Otolaryngology, University of Florida, Gainesville, Florida 32610-0264, USA.

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April 2005

Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts.

Am J Respir Cell Mol Biol 2005 Apr 27;32(4):290-300. Epub 2005 Jan 27.

Lung Research, Institute of Science and Technology in Medicine, University Hospital of North Stafforshire/Keel University, School of Postgraduate Medicine, Thornburrow Drive, Hartshill, Stoke on Trent ST4 7NQ, UK.

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April 2005

Microarray analysis of the failure of filtering blebs in a rat model of glaucoma filtering surgery.

Invest Ophthalmol Vis Sci 2004 Dec;45(12):4450-62

Department of Ophthalmology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610-0284, USA.

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December 2004

TIME heals all wounds.

Nursing 2004 Apr;34(4):36-41; quiz, 41-2

John A. Hartford Institute of Geriatric Nursing, Division of Nursing, New York University, New York, N.Y., USA.

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April 2004

Hammerhead ribozyme targeting connective tissue growth factor mRNA blocks transforming growth factor-beta mediated cell proliferation.

Exp Eye Res 2004 Jun;78(6):1127-36

Department of Ob/Gyn, College of Medicine, Institute for Wound Research, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610-0294, USA.

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June 2004

Tympanic membrane metalloproteinase inflammatory response.

Otolaryngol Head Neck Surg 2003 Dec;129(6):647-54

Department of Otolaryngology, University of Florida, Gainesville, FL 32610-0264, USA.

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December 2003

Preparing the wound bed 2003: focus on infection and inflammation.

Ostomy Wound Manage 2003 Nov;49(11):24-51

Department of Medicine, University of Toronto, Toronto, Canada.

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November 2003

The effect of topical tripeptide-copper complex on healing of ischemic open wounds.

Vet Surg 2003 Nov-Dec;32(6):515-23

Department of Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, and the School of Medicine Institute for Wound Research, Gainesville, FL 32610, USA.

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February 2004

Analysis of gene expression patterns in human postburn hypertrophic scars.

J Burn Care Rehabil 2003 Nov-Dec;24(6):371-7

Department of Surgery, Institute for Wound Research, University of Florida Genetics Institute, University of Florida College of Medicine, Gainesville, Florida 32610-0286, USA.

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March 2004

Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring.

Am J Pathol 2003 Nov;163(5):2043-52

Epithelial Repair and Regeneration Group, Wound Healing Research Unit, Divisions of Pathology and Cell Biology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom.

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November 2003

Matrix metalloproteinases in a gerbil cholesteatoma model.

Otolaryngol Head Neck Surg 2003 Oct;129(4):402-7

Department of Otolaryngology, University of Florida, Gainesville, Florida 32610, USA.

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October 2003

Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla.

Laryngoscope 2003 Oct;113(10):1764-9

Department of Otolaryngology, University of Florida, Box 100264, 1600 SW Archer Road, Gainesville, FL 32610-0264, USA.

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October 2003

Methods in reepithelialization. A porcine model of partial-thickness wounds.

Methods Mol Med 2003 ;78:17-36

Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.

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November 2003

Role of connective tissue growth factor in breast implant elastomer capsular formation.

Ann Plast Surg 2003 Mar;50(3):263-8; discussion 268

Division of Plastic & Reconstructive Surgery, University of Florida College of Medicine, Gainesville, FL 32610-0286, USA.

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March 2003

Detection of connective tissue growth factor (CTGF) in human tear fluid: preliminary results.

Acta Ophthalmol Scand 2003 Feb;81(1):51-3

St. Erik's Eye Clinic, Karolinska Institute, Polhemsgatan 50, S-112 82 Stockholm, Sweden.

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February 2003

Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro.

Invest Ophthalmol Vis Sci 2003 Mar;44(3):1104-10

Wound Healing Research Unit, Department of Pathology and Glaucoma, Institute of Ophthalmology and Moorfields Eye Hospital, London, United Kingdom.

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March 2003

Gene transfer into rabbit keratocytes using AAV and lipid-mediated plasmid DNA vectors with a lamellar flap for stromal access.

Exp Eye Res 2003 Mar;76(3):373-83

Department of Ophthalmology, University of Washington School of Medicine, Box 356485, Seattle, WA 98195-6485, USA.

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March 2003

Detection of connective tissue growth factor in human aqueous humor.

Ophthalmic Res 2002 Sep-Oct;34(5):306-8

St. Eriks Eye Clinic, Karolinska Institutet, Stockholm, Sweden.

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January 2003

Microarray analysis of gene expression patterns during healing of rat corneas after excimer laser photorefractive keratectomy.

Invest Ophthalmol Vis Sci 2002 Jun;43(6):1772-82

Institute for Wound Research and Department of Ophthalmology, University of Florida, Gainesville, Florida 32610-0294, USA.

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June 2002

Inhibition of matrix metalloproteinases in gerbil cholesteatoma: preliminary findings.

Otolaryngol Head Neck Surg 2002 Apr;126(4):404-8

Department of Otolaryngology, University of Florida, Gainesville 32610-0264, USA.

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April 2002