Publications by authors named "Gregory M Cote"

42Publications

Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma.

Ther Adv Med Oncol 2020 14;12:1758835920956900. Epub 2020 Sep 14.

Sarcoma Biology Laboratory, Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, 615 Charles E. Young Dr. S., Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1177/1758835920956900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493280PMC
September 2020

Case 36-2019: A 34-Year-Old Man with Dyspnea, Odynophagia, and Abdominal Pain.

N Engl J Med 2019 11;381(21):2052-2061

From the Department of Medicine, University of Alabama Birmingham School of Medicine, Birmingham (M.S.); and the Departments of Radiology (D.P.M.), Medicine (M.S.S., G.M.C.), and Pathology (A.R.S.), Massachusetts General Hospital, and the Departments of Radiology (D.P.M.), Medicine (M.S.S., G.M.C.), and Pathology (A.R.S.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1909625DOI Listing
November 2019

Radiation-induced and neurofibromatosis-associated malignant peripheral nerve sheath tumors (MPNST) have worse outcomes than sporadic MPNST.

Radiother Oncol 2019 08 9;137:61-70. Epub 2019 May 9.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, USA; Harvard Medical School, Boston, USA. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2019.03.015DOI Listing
August 2019

Characteristics and Predictors for Secondary Leukemia and Myelodysplastic Syndrome in Ewing and Osteosarcoma Survivors.

Int J Radiat Oncol Biol Phys 2019 01 28;103(1):52-61. Epub 2018 Aug 28.

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.08.037DOI Listing
January 2019

A Phase 1 Study of Nilotinib Plus Radiation in High-Risk Chordoma.

Int J Radiat Oncol Biol Phys 2018 12 3;102(5):1496-1504. Epub 2018 Aug 3.

Division of Hematology-Oncology, Massachusetts General Hospital, Boston, Massachusetts; Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2018.07.2013DOI Listing
December 2018

Clinicopathologic characteristics of poorly differentiated chordoma.

Mod Pathol 2018 08 26;31(8):1237-1245. Epub 2018 Feb 26.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41379-018-0002-1DOI Listing
August 2018

Secondary Acute Leukemia in Sarcoma Patients: A Population-Based Study.

Int J Radiat Oncol Biol Phys 2018 03 14;100(3):687-694. Epub 2017 Nov 14.

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2017.11.011DOI Listing
March 2018

Contemporary Sarcoma Diagnosis, Genetics, and Genomics.

J Clin Oncol 2018 01 8;36(2):101-110. Epub 2017 Dec 8.

Inga-Marie Schaefer and Jason L. Hornick, Brigham and Women's Hospital-Harvard Medical School; and Gregory M. Cote, Massachusetts General Hospital Cancer Center-Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2017.74.9374DOI Listing
January 2018

Next-Generation Sequencing for Patients with Sarcoma: A Single Center Experience.

Oncologist 2018 02 31;23(2):234-242. Epub 2017 Aug 31.

Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1634/theoncologist.2017-0290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813739PMC
February 2018

Targeting EZH2-mediated methylation of H3K27 inhibits proliferation and migration of Synovial Sarcoma in vitro.

Sci Rep 2016 04 29;6:25239. Epub 2016 Apr 29.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, United States.

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http://dx.doi.org/10.1038/srep25239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850444PMC
April 2016

Rank ligand as a target in musculoskeletal neoplasms.

Authors:
Gregory M Cote

Curr Rev Musculoskelet Med 2015 Dec;8(4):339-43

Massachusetts General Hospital Cancer Center, Boston, MA, USA.

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http://dx.doi.org/10.1007/s12178-015-9310-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630234PMC
December 2015

CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma.

Sci Rep 2015 Jun 16;5:11365. Epub 2015 Jun 16.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.

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http://www.nature.com/articles/srep11365
Publisher Site
http://dx.doi.org/10.1038/srep11365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468826PMC
June 2015

Targeting programmed cell death ligand 1 in osteosarcoma: an auto-commentary on therapeutic potential.

Oncoimmunology 2014;3(8):e954467. Epub 2014 Aug 3.

Sarcoma Biology Laboratory; Center for Sarcoma and Connective Tissue Oncology; Massachusetts General Hospital ; Boston, MA USA.

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http://dx.doi.org/10.4161/21624011.2014.954467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292524PMC
August 2014

Programmed cell death ligand 1 expression in osteosarcoma.

Cancer Immunol Res 2014 Jul 21;2(7):690-698. Epub 2014 Apr 21.

Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, United States.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082476PMC
July 2014

Update in treatment and targets in Ewing sarcoma.

Hematol Oncol Clin North Am 2013 Oct 3;27(5):1007-19. Epub 2013 Aug 3.

Division of Hematology Oncology, Yawkey Center for Outpatient Care, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.hoc.2013.07.001DOI Listing
October 2013

Role of epigenetic modulation for the treatment of sarcoma.

Curr Treat Options Oncol 2013 Sep;14(3):454-64

, 32 Fruit Street, Yawkey 7A, Boston, MA, 02114, USA,

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http://dx.doi.org/10.1007/s11864-013-0239-3DOI Listing
September 2013

ERBB2 inhibition and heart failure.

N Engl J Med 2013 02;368(9):876

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http://dx.doi.org/10.1056/NEJMc1215887DOI Listing
February 2013

ERBB2 inhibition and heart failure.

N Engl J Med 2012 Nov;367(22):2150-3

Massachusetts General Hospital Cancer Center, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcibr1203156DOI Listing
November 2012

Can low-risk, early-stage patients with Hodgkin lymphoma be spared radiotherapy?

Curr Hematol Malig Rep 2011 Sep;6(3):180-6

Dana-Farber/Harvard Cancer Center, Boston, MA 02114, USA.

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http://dx.doi.org/10.1007/s11899-011-0088-8DOI Listing
September 2011

Palmitate alters neuregulin signaling and biology in cardiac myocytes.

Biochem Biophys Res Commun 2009 Jan 12;379(1):32-7. Epub 2008 Dec 12.

Boston University School of Medicine, Department of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.bbrc.2008.11.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654183PMC
January 2009

Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro.

Exp Cell Res 2005 Nov 26;311(1):135-46. Epub 2005 Sep 26.

Whitaker Cardiovascular Institute and Molecular Stress Response Unit, Cardiovascular Division, Department of Medicine, Boston University Medical Center, 650 Albany Street, Boston, X-320, MA 02118, USA.

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http://dx.doi.org/10.1016/j.yexcr.2005.08.017DOI Listing
November 2005

Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes.

Biochem Biophys Res Commun 2005 Oct;336(1):309-15

Molecular Stress Response Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/j.bbrc.2005.08.088DOI Listing
October 2005

Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling.

J Biol Chem 2004 Dec 21;279(49):51141-7. Epub 2004 Sep 21.

Center of Molecular Stress Response, Whitaker Cardiovascular Institute, Department of Medicine, Boston University Medical Center, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1074/jbc.M408662200DOI Listing
December 2004

Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle.

Am J Physiol Cell Physiol 2003 May 2;284(5):C1149-55. Epub 2003 Jan 2.

Myocardial Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston 02218, USA.

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http://dx.doi.org/10.1152/ajpcell.00487.2002DOI Listing
May 2003