Gregory L Holmes

Gregory L Holmes

UNVERIFIED PROFILE

Are you Gregory L Holmes?   Register this Author

Register author
Gregory L Holmes

Gregory L Holmes

Publications by authors named "Gregory L Holmes"

Are you Gregory L Holmes?   Register this Author

99Publications

1252Reads

14Profile Views

Construction and disruption of spatial memory networks during development.

Learn Mem 2019 Jul 17;26(7):206-218. Epub 2019 Jun 17.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont 05401, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/lm.049239.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581006PMC
July 2019

Functional brain connectivity in a rodent seizure model of autistic-like behavior.

Epilepsy Behav 2019 Jun 24;95:87-94. Epub 2019 Apr 24.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT 05405, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2019.03.046DOI Listing
June 2019

Functional Connectivity in Term Neonates With Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia.

Pediatr Neurol 2019 May 9;94:74-79. Epub 2019 Jan 9.

Department of Pediatrics, Larner College of Medicine, University of Vermont, Burlington, Vermont.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pediatrneurol.2019.01.006DOI Listing
May 2019

Functional brain connectivity in electrical status epilepticus in sleep.

Epileptic Disord 2019 Feb;21(1):55-64

Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/epd.2019.1027DOI Listing
February 2019

Spindle activity in young children with autism, developmental delay, or typical development.

Neurology 2018 07 6;91(2):e112-e122. Epub 2018 Jun 6.

From the National Institute of Mental Health (C.A.F., A.E.T., S.E.S., A.W.B.), NIH, Bethesda, MD; and Department of Neurological Sciences (P.C., G.L.H.), University of Vermont, Burlington.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000005759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053112PMC
July 2018

A Review of the New Antiepileptic Drugs for Focal-Onset Seizures in Pediatrics: Role of Extrapolation.

Paediatr Drugs 2018 Jun;20(3):249-264

Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, VT, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40272-018-0286-0DOI Listing
June 2018

Environmental enrichment normalizes hippocampal timing coding in a malformed hippocampus.

PLoS One 2018 2;13(2):e0191488. Epub 2018 Feb 2.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191488PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796690PMC
March 2018

Inhibition of blood-brain barrier efflux transporters promotes seizure in pregnant rats: Role of circulating factors.

Brain Behav Immun 2018 Jan 21;67:13-23. Epub 2017 Jul 21.

Department of Neurological Sciences, University of Vermont Larner College of Medicine, Burlington, VT 05405, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Vermont Larner College of Medicine, Burlington, VT 05405, USA; Department of Pharmacology, University of Vermont Larner College of Medicine, Burlington, VT 05405, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbi.2017.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696046PMC
January 2018

Extrapolating evidence of antiepileptic drug efficacy in adults to children ≥2 years of age with focal seizures: The case for disease similarity.

Epilepsia 2017 10 29;58(10):1686-1696. Epub 2017 Jul 29.

Departments of Neurology, Pediatrics, and Epidemiology and Population Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.13859DOI Listing
October 2017

Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus.

Epilepsy Behav 2017 02 13;67:66-69. Epub 2017 Jan 13.

Department of Cellular Membranology, Bogomoletz Institute of Physiology, Kiev, Ukraine; Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2016.11.003DOI Listing
February 2017

Rapid and safe response to low-dose carbamazepine in neonatal epilepsy.

Epilepsia 2016 12 26;57(12):2019-2030. Epub 2016 Nov 26.

Department of Neurology, University of California San Francisco, San Francisco, California, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.13596DOI Listing
December 2016

Why Are Children With Epileptic Encephalopathies Encephalopathic?

J Child Neurol 2016 11 11;31(13):1495-1504. Epub 2016 Aug 11.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0883073816662140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410364PMC
November 2016

Diagnosing infantile spasms: Accuracy of the internet.

Epilepsy Behav 2016 11 17;64(Pt A):239-241. Epub 2016 Oct 17.

Department of Neurological Sciences, University of Vermont, College of Medicine, Burlington, VT, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2016.09.004DOI Listing
November 2016

Spatial cognition following early-life seizures in rats: Performance deficits are dependent on task demands.

Epilepsy Behav 2016 07 4;60:1-6. Epub 2016 May 4.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT 05405, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15255050163000
Publisher Site
http://dx.doi.org/10.1016/j.yebeh.2016.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912871PMC
July 2016

The Epilepsy Spectrum: Targeting Future Research Challenges.

Cold Spring Harb Perspect Med 2016 07 1;6(7). Epub 2016 Jul 1.

Developmental Neurogenetics Laboratory, Departments of Neurology, Neuroscience, and Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a028043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930917PMC
July 2016

Oscillation Phase Locking and Late ERP Components of Intracranial Hippocampal Recordings Correlate to Patient Performance in a Working Memory Task.

Front Hum Neurosci 2016 16;10:287. Epub 2016 Jun 16.

Department of Neurological Sciences, University of Vermont College of MedicineBurlington, VT, USA; INMED Institut National de la Santé et de la Recherche Médicale U901Marseille, France; Aix Marseille Université, INMEDMarseille, France.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/Article/10.3389/fnhum.2016.00
Publisher Site
http://dx.doi.org/10.3389/fnhum.2016.00287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910536PMC
July 2016

ACTH Prevents Deficits in Fear Extinction Associated with Early Life Seizures.

Front Neurol 2016 2;7:65. Epub 2016 May 2.

Department of Neurological Sciences, University of Vermont College of Medicine , Burlington, VT , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2016.00065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852169PMC
May 2016

Temporal Coordination of Hippocampal Neurons Reflects Cognitive Outcome Post-febrile Status Epilepticus.

EBioMedicine 2016 May 6;7:175-90. Epub 2016 Apr 6.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2016.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909381PMC
May 2016

Effect of Seizures on the Developing Brain and Cognition.

Authors:
Gregory L Holmes

Semin Pediatr Neurol 2016 05 24;23(2):120-6. Epub 2016 May 24.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10719091163000
Publisher Site
http://dx.doi.org/10.1016/j.spen.2016.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410363PMC
May 2016

Status Epilepticus Induced Spontaneous Dentate Gyrus Spikes: In Vivo Current Source Density Analysis.

PLoS One 2015 6;10(7):e0132630. Epub 2015 Jul 6.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132630PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492740PMC
April 2016

Epilepsy and Autism.

Cold Spring Harb Perspect Med 2016 Apr 1;6(4):a022749. Epub 2016 Apr 1.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont 05405.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a022749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817741PMC
April 2016

State-Dependent Differences in Functional Connectivity in Young Children With Autism Spectrum Disorder.

EBioMedicine 2015 Dec 5;2(12):1905-15. Epub 2015 Nov 5.

National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Room 1C250, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2015.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703709PMC
December 2015

Neuraminidase inhibition primes short-term depression and suppresses long-term potentiation of synaptic transmission in the rat hippocampus.

Neural Plast 2015 31;2015:908190. Epub 2015 Jan 31.

Department of Cellular Membranology, Bogomoletz Institute of Physiology, Bogomoletz Street 4, Kiev 01024, Ukraine ; Department of Neurological Sciences, University of Vermont, 149 Beaumont Avenue, Burlington, VT 05405, USA.

View Article

Download full-text PDF

Source
http://www.hindawi.com/journals/np/2015/908190/
Publisher Site
http://dx.doi.org/10.1155/2015/908190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329761PMC
November 2015

Seizing control of epileptic activity can improve outcome.

Epilepsia 2015 Oct 21;56(10):1482-5. Epub 2015 Aug 21.

Neurology, University of Vermont, Burlington, Vermont, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.13109DOI Listing
October 2015

Cognitive impairment in epilepsy: the role of network abnormalities.

Authors:
Gregory L Holmes

Epileptic Disord 2015 Jun;17(2):101-16

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/epd.2015.0739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410366PMC
June 2015

Alterations in sociability and functional brain connectivity caused by early-life seizures are prevented by bumetanide.

Neurobiol Dis 2015 May 10;77:204-19. Epub 2015 Mar 10.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT05405, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2015.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682568PMC
May 2015

Status epilepticus results in region-specific alterations in seizure susceptibility along the hippocampal longitudinal axis.

Epilepsy Res 2015 Feb 17;110:166-70. Epub 2014 Dec 17.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, USA; Department of Cellular Membranology, Bogomoletz Institute of Physiology, Kiev, Ukraine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eplepsyres.2014.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361808PMC
February 2015

Attention deficit associated with early life interictal spikes in a rat model is improved with ACTH.

PLoS One 2014 24;9(2):e89812. Epub 2014 Feb 24.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089812PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933669PMC
January 2015

What is more harmful, seizures or epileptic EEG abnormalities? Is there any clinical data?

Authors:
Gregory L Holmes

Epileptic Disord 2014 Oct;16 Spec No 1:S12-22

Department of Neurological Sciences, University of Vermont, College of Medicine, Burlington, Vermont, USA.

View Article

Download full-text PDF

Source
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ep
Publisher Site
http://dx.doi.org/10.1684/epd.2014.0686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410369PMC
October 2014

Brain connectivity in West syndrome.

Seizure 2014 Aug 4;23(7):576-9. Epub 2014 Apr 4.

Department of Neurology, Geisel School of Medicine at Dartmouth, Hanover, NH, United States; Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.seizure.2014.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361818PMC
August 2014

Transitory effect of spike and spike-and-wave discharges on EEG power in children.

Brain Dev 2014 Jun 1;36(6):505-9. Epub 2013 Aug 1.

Department of Neurology, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Hanover, NH, United States; Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.braindev.2013.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874075PMC
June 2014

To know or not to know: does EEG monitoring in the paediatric intensive care unit add anything besides cost?

Authors:
Gregory L Holmes

Brain 2014 May;137(Pt 5):1276-7

Department of Neurological Sciences University of Vermont College of Medicine Burlington, Vermont, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/brain/article-lookup/doi/10.1093/br
Publisher Site
http://dx.doi.org/10.1093/brain/awu080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805075PMC
May 2014

Brain maturation and epilepsy.

Handb Clin Neurol 2013 ;111:441-6

Department of Pediatric Neurology, Hôpital Necker-Enfants Malades, UMR663, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-444-52891-9.00047-6DOI Listing
April 2014

Short duration waveforms recorded extracellularly from freely moving rats are representative of axonal activity.

Front Neural Circuits 2013 18;7:181. Epub 2013 Nov 18.

Department of Neurology, Geisel School of Medicine at Dartmouth Lebanon, NH, USA ; Epilepsy and Development Group, Department of Neurological Sciences, University of Vermont College of Medicine Burlington, VT, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncir.2013.00181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831546PMC
April 2014

Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits.

Neurobiol Dis 2014 Mar 19;63:25-34. Epub 2013 Nov 19.

Department of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, USA 05405; University College London, Institute of Child Health, London WC1N 1EH, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2013.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397918PMC
March 2014

Validity of the Neurology Quality-of-Life (Neuro-QoL) measurement system in adult epilepsy.

Epilepsy Behav 2014 Feb 20;31:77-84. Epub 2013 Dec 20.

Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2013.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970783PMC
February 2014

Isoflurane suppresses early cortical activity.

Ann Clin Transl Neurol 2014 Jan 20;1(1):15-26. Epub 2013 Nov 20.

INMED, INSERM U-901 Marseille, France ; Aix-Marseille University Marseille, France ; Laboratory of Neurobiology, Kazan Federal University Kazan, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/acn3.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207500PMC
January 2014

Speed modulation of hippocampal theta frequency correlates with spatial memory performance.

Hippocampus 2013 Dec 5;23(12):1269-79. Epub 2013 Aug 5.

Department of Neurology, Geisel School of Medicine, Hanover, New Hampshire.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.22164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410367PMC
December 2013

Authors' response to letter by A. Mazarati.

Epilepsia 2013 Dec;54(12):2229-30

Departments of Pediatrics, Neurology and Pharmaceutical Sciences, Children's Hospital Colorado, University of Colorado Schools of Medicine and Pharmacy, Aurora, Colorado, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.12414DOI Listing
December 2013

Alteration of synaptic plasticity by neonatal seizures in rat somatosensory cortex.

Epilepsy Res 2013 Sep 25;106(1-2):280-3. Epub 2013 Apr 25.

Department of Neurology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eplepsyres.2013.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758912PMC
September 2013

Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy.

Epilepsia 2013 Aug;54 Suppl 4:44-60

Departments of Pediatrics, Neurology and Pharmaceutical Sciences, University of Colorado Schools of Medicine and Pharmacy, Children's Hospital Colorado, Aurora, Colorado, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.12298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924317PMC
August 2013

Hippocampal interictal epileptiform activity disrupts cognition in humans.

Neurology 2013 Jul 17;81(1):18-24. Epub 2013 May 17.

Department of Neurology, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0b013e318297ee50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770206PMC
July 2013

Focal Scn1a knockdown induces cognitive impairment without seizures.

Neurobiol Dis 2013 Jun 11;54:297-307. Epub 2013 Jan 11.

Department of Neurology, Neuroscience Center at Dartmouth, Geisel School of Medicine at Dartmouth, Hanover, NH03756,USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2012.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628954PMC
June 2013

EEG abnormalities as a biomarker for cognitive comorbidities in pharmacoresistant epilepsy.

Authors:
Gregory L Holmes

Epilepsia 2013 May;54 Suppl 2:60-2

Department of Neurology, Neuroscience Center at Dartmouth, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.12186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682563PMC
May 2013

Inter-rater agreement for diagnoses of epilepsy in pregnant women.

Epilepsy Behav 2013 Apr 15;27(1):148-53. Epub 2013 Feb 15.

Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2012.12.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602402PMC
April 2013

Searching for new targets for treatment of pediatric epilepsy.

Epilepsy Behav 2013 Mar 6;26(3):253-60. Epub 2012 Dec 6.

Department of Anatomy & Neurobiology, University of California-Irvine, Irvine, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2012.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595393PMC
March 2013

Maturation of the human brain and epilepsy.

Handb Clin Neurol 2012 ;107:135-43

Department of Neurology, Dartmouth Medical School, Lebanon, NH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-444-52898-8.00007-0DOI Listing
December 2012

Before epilepsy unfolds: opening up the potassium door in neonatal seizures.

Nat Med 2012 Nov;18(11):1624-5

University College London, Institute of Child Health, London, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nm.2987
Publisher Site
http://dx.doi.org/10.1038/nm.2987DOI Listing
November 2012

Electrolyte therapy reduces spike-and-wave discharges in the WAG/Rij rat model of absence epilepsy.

Epilepsy Behav 2012 Aug 28;24(4):399-402. Epub 2012 Jun 28.

Department of Physiology of Movements, Bogomoletz Institute of Physiology, Kiev, Ukraine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2012.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408819PMC
August 2012

Febrile seizures and the wandering granule cell.

Nat Med 2012 Aug;18(8):1180-2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.2898DOI Listing
August 2012

Thrombin facilitates seizures through activation of persistent sodium current.

Ann Neurol 2012 Aug;72(2):192-8

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Lebanon, NH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.23587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430976PMC
August 2012

Maturation of EEG oscillations in children with sodium channel mutations.

Brain Dev 2012 Jun 21;34(6):469-77. Epub 2011 Sep 21.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.braindev.2011.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278588PMC
June 2012

SCN1A mutations in Dravet syndrome: impact of interneuron dysfunction on neural networks and cognitive outcome.

Epilepsy Behav 2012 Mar 16;23(3):177-86. Epub 2012 Feb 16.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2011.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307886PMC
March 2012

Quality-of-life measures in children with neurological conditions: pediatric Neuro-QOL.

Neurorehabil Neural Repair 2012 Jan 25;26(1):36-47. Epub 2011 Jul 25.

Department of Medical Social Sciences, Feinberg School of Medicine at Northwestern University, Chicago, IL 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1545968311412054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710728PMC
January 2012

Surface charge impact in low-magnesium model of seizure in rat hippocampus.

J Neurophysiol 2012 Jan 26;107(1):417-23. Epub 2011 Oct 26.

Dept. of General Physiology of Nervous System, Bogomoletz Institute of Physiology, 4 Bogomoletz Str, Kiev 01024, Ukraine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/jn.00574.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349697PMC
January 2012

Effect of neuraminidase treatment on persistent epileptiform activity in the rat hippocampus.

Pharmacol Rep 2011 ;63(3):840-4

Department of General Physiology of Nervous System, Bogomoletz Institute of Physiology, Bogomoletz st. 4, Kiev, Ukraine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1734-1140(11)70597-7DOI Listing
December 2011

Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex.

Epilepsy Behav 2011 Oct 27;22(2):214-9. Epub 2011 Aug 27.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2011.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185212PMC
October 2011

Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures.

J Neurosci 2011 Oct;31(43):15397-406

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.2196-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224083PMC
October 2011

Pediatric epileptology.

Epilepsy Behav 2011 Sep 6;22(1):32-7. Epub 2011 May 6.

Department of Neurology, Children's Hospital Boston, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2011.02.010DOI Listing
September 2011

Impaired cognition in rats with cortical dysplasia: additional impact of early-life seizures.

Brain 2011 Jun 20;134(Pt 6):1684-93. Epub 2011 May 20.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, One Medical Center Drive, Lebanon, New Hampshire, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awr087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102240PMC
June 2011

Education of a child neurologist: epilepsy and electroencephalography.

Semin Pediatr Neurol 2011 Jun;18(2):74-8

Department of Pediatrics, Dartmouth Medical School, Lebanon, NH, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S107190911100032
Publisher Site
http://dx.doi.org/10.1016/j.spen.2011.05.002DOI Listing
June 2011

Maturational dynamics of hippocampal place cells in immature rats.

Hippocampus 2011 Apr;21(4):347-53

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Dartmouth College, Hanover, New Hampshire 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.20789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010481PMC
April 2011

Power spectral analysis in infants with seizures: relationship to development.

Epilepsy Behav 2011 Apr 24;20(4):700-5. Epub 2011 Mar 24.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2011.02.021DOI Listing
April 2011

Neuroaminidase reduces interictal spikes in a rat temporal lobe epilepsy model.

Epilepsia 2011 Mar 2;52(3):e12-5. Epub 2011 Mar 2.

Department of General Physiology of Nervous System, Bogomoletz Institute of Physiology, Kiev, Ukraine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1528-1167.2011.02988.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265164PMC
March 2011

Blockade of endogenous neuraminidase leads to an increase of neuronal excitability and activity-dependent synaptogenesis in the rat hippocampus.

Eur J Neurosci 2010 Dec 29;32(11):1889-96. Epub 2010 Oct 29.

Department of General Physiology of Nervous System, Bogomoletz Institute of Physiology, Kiev, Ukraine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1460-9568.2010.07468.xDOI Listing
December 2010

Infantile spasms: a U.S. consensus report.

Epilepsia 2010 Oct;51(10):2175-89

Division of Child Neurology, Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1528-1167.2010.02657.xDOI Listing
October 2010

Interictal spikes in developing rats cause long-standing cognitive deficits.

Neurobiol Dis 2010 Sep 7;39(3):362-71. Epub 2010 May 7.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, New Hampshire 03756, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S096999611000153
Publisher Site
http://dx.doi.org/10.1016/j.nbd.2010.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910186PMC
September 2010

Taming TLR4 may ease seizures.

Nat Med 2010 Apr;16(4):369-70

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm0410-369DOI Listing
April 2010

Recurrent neonatal seizures result in long-term increases in neuronal network excitability in the rat neocortex.

Eur J Neurosci 2010 Apr 6;31(8):1446-55. Epub 2010 Apr 6.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Lebanon, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1460-9568.2010.07179.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148010PMC
April 2010

Hippocampal interictal spikes disrupt cognition in rats.

Ann Neurol 2010 Feb;67(2):250-7

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, New Hampshire.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.21896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926932PMC
February 2010

Long-term suppression of GABAergic activity by neonatal seizures in rat somatosensory cortex.

Epilepsy Res 2009 Dec 13;87(2-3):286-9. Epub 2009 Oct 13.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Lebanon, NH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eplepsyres.2009.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788005PMC
December 2009

The long-term effects of neonatal seizures.

Authors:
Gregory L Holmes

Clin Perinatol 2009 Dec;36(4):901-14, vii-viii

Department of Neurology, Dartmouth-Hitchcock Medical Center, Neuroscience Center at Dartmouth, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clp.2009.07.012DOI Listing
December 2009

The 2008 Judith Hoyer lecture: epilepsy in children: listening to mothers.

Authors:
Gregory L Holmes

Epilepsy Behav 2009 Oct 31;16(2):193-202. Epub 2009 Aug 31.

Department of Neurology, Center for Neuroscience at Dartmouth, Dartmouth Medical School, Hanover, NH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yebeh.2009.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760824PMC
October 2009

Recurrent seizures induce a reversible impairment in a spatial hidden goal task.

Hippocampus 2009 Sep;19(9):817-27

Program in Neural and Behavioral Science, SUNY Downstate Medical Center, Brooklyn, New York 11203, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.20565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466816PMC
September 2009

Effect of age on cognitive sequelae following early life seizures in rats.

Epilepsy Res 2009 Aug 22;85(2-3):221-30. Epub 2009 Apr 22.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, New Hampshire 03756, United States.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S092012110900086
Publisher Site
http://dx.doi.org/10.1016/j.eplepsyres.2009.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795326PMC
August 2009

Early life seizures cause long-standing impairment of the hippocampal map.

Exp Neurol 2009 Jun 2;217(2):378-87. Epub 2009 Apr 2.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2009.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791529PMC
June 2009

Benign neonatal sleep myoclonus: history and semiology.

Pediatr Neurol 2009 May;40(5):343-6

Hurley Medical Center, Flint, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pediatrneurol.2008.11.011DOI Listing
May 2009

Commentary: novel delivery approaches for antiepileptic drugs: hope and hurdles.

Neurotherapeutics 2009 Apr;6(2):381-2

Epilepsy Research Group, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nurt.2009.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084217PMC
April 2009

Effect of topiramate on cognitive function and single units from hippocampal place cells following status epilepticus.

Epilepsy Behav 2009 Jan 7;14(1):40-7. Epub 2008 Nov 7.

Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S152550500800296
Publisher Site
http://dx.doi.org/10.1016/j.yebeh.2008.09.030DOI Listing
January 2009

Cognitive dysfunction after experimental febrile seizures.

Exp Neurol 2009 Jan 22;215(1):167-77. Epub 2008 Oct 22.

Department of Pediatrics, ZOT 4475, University of California, Irvine 92697-4475, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2008.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649663PMC
January 2009

Commentary on "Factors influencing clinical features of absence seizures".

Authors:
Gregory L Holmes

Epilepsia 2008 Dec;49(12):2141-3

Department of Neurology, Dartmouth Medical School, Hanover, New Hampshire, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1528-1167.2008.01818.x
Publisher Site
http://dx.doi.org/10.1111/j.1528-1167.2008.01818.xDOI Listing
December 2008

Brain inflammation initiates seizures.

Nat Med 2008 Dec;14(12):1309-10

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm1208-1309DOI Listing
December 2008

Should all patients be told about sudden unexpected death in epilepsy (SUDEP)? Pros and Cons.

Epilepsia 2008 Dec;49 Suppl 9:99-101

Epilepsy Unit, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, Scotland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1528-1167.2008.01933.xDOI Listing
December 2008

What constitutes a relevant animal model of the ketogenic diet?

Authors:
Gregory L Holmes

Epilepsia 2008 Nov;49 Suppl 8:57-60

Neuroscience Center at Dartmouth, Department of Neurology, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1528-1167.2008.01836.x
Publisher Site
http://dx.doi.org/10.1111/j.1528-1167.2008.01836.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653859PMC
November 2008