Gregory J Tranah

Gregory J Tranah

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Gregory J Tranah

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Response: Low Heteroplasmy Rates of Pathogenic mtDNA Variants Do Not Predict Aging.

Authors:
Gregory J Tranah

J Gerontol A Biol Sci Med Sci 2019 Jun;74(7):1027-1028

California Pacific Medical Center Research Institute, San Francisco, California.

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http://dx.doi.org/10.1093/gerona/gly216DOI Listing
June 2019

Relationship Between Poor Olfaction and Mortality Among Community-Dwelling Older Adults: A Cohort Study.

Ann Intern Med 2019 Apr 30. Epub 2019 Apr 30.

Michigan State University College of Human Medicine, East Lansing, Michigan (Z.L., H.C.).

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http://dx.doi.org/10.7326/M18-0775DOI Listing
April 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 Feb;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Mitochondrial DNA m.13514G>A heteroplasmy is associated with depressive symptoms in the elderly.

Int J Geriatr Psychiatry 2018 10 8;33(10):1319-1326. Epub 2018 Jul 8.

California Pacific Medical Center Research Institute, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/gps.4928DOI Listing
October 2018

APOEε4 and slow wave sleep in older adults.

PLoS One 2018 25;13(1):e0191281. Epub 2018 Jan 25.

Research Institute, California Pacific Medical Center, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191281PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784964PMC
February 2018

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Olfaction and incident Parkinson disease in US white and black older adults.

Neurology 2017 Oct 6;89(14):1441-1447. Epub 2017 Sep 6.

From the Epidemiology Branch (H.C., S. Shrestha), National Institute of Environmental Health Sciences, Research Triangle Park, NC; Department of Epidemiology and Biostatistics (H.C.), College of Human Medicine, Michigan State University, East Lansing; Department of Neurology (X.H.), Pennsylvania State University College of Medicine, Hershey; Department of Neurology (S.J.), University of Pittsburgh School of Medicine, PA; Westat Inc. (X.G.), Durham, NC; California Pacific Medical Center Research Institute (G.J.T.), San Francisco; Laboratory of Epidemiology, Demography, and Biometry (M.E.G., C.P., T.B.H.), National Institute on Aging, Bethesda, MD; and Department of Preventive Medicine (S. Satterfield), University of Tennessee Health Science Center, Memphis. M.E.G. is currently affiliated with the National Heart, Lung, and Blood Institute, Bethesda, MD.

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http://dx.doi.org/10.1212/WNL.0000000000004382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631167PMC
October 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Genetic variants in RBFOX3 are associated with sleep latency.

Eur J Hum Genet 2016 10 4;24(10):1488-95. Epub 2016 May 4.

Unit of Genetic Epidemiology, Department of Epidemiology, Erasmus University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2016.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027680PMC
October 2016

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

Authors:
Yingchang Lu Felix R Day Stefan Gustafsson Martin L Buchkovich Jianbo Na Veronique Bataille Diana L Cousminer Zari Dastani Alexander W Drong Tõnu Esko David M Evans Mario Falchi Mary F Feitosa Teresa Ferreira Åsa K Hedman Robin Haring Pirro G Hysi Mark M Iles Anne E Justice Stavroula Kanoni Vasiliki Lagou Rui Li Xin Li Adam Locke Chen Lu Reedik Mägi John R B Perry Tune H Pers Qibin Qi Marianna Sanna Ellen M Schmidt William R Scott Dmitry Shungin Alexander Teumer Anna A E Vinkhuyzen Ryan W Walker Harm-Jan Westra Mingfeng Zhang Weihua Zhang Jing Hua Zhao Zhihong Zhu Uzma Afzal Tarunveer Singh Ahluwalia Stephan J L Bakker Claire Bellis Amélie Bonnefond Katja Borodulin Aron S Buchman Tommy Cederholm Audrey C Choh Hyung Jin Choi Joanne E Curran Lisette C P G M de Groot Philip L De Jager Rosalie A M Dhonukshe-Rutten Anke W Enneman Elodie Eury Daniel S Evans Tom Forsen Nele Friedrich Frédéric Fumeron Melissa E Garcia Simone Gärtner Bok-Ghee Han Aki S Havulinna Caroline Hayward Dena Hernandez Hans Hillege Till Ittermann Jack W Kent Ivana Kolcic Tiina Laatikainen Jari Lahti Irene Mateo Leach Christine G Lee Jong-Young Lee Tian Liu Youfang Liu Stéphane Lobbens Marie Loh Leo-Pekka Lyytikäinen Carolina Medina-Gomez Karl Michaëlsson Mike A Nalls Carrie M Nielson Laticia Oozageer Laura Pascoe Lavinia Paternoster Ozren Polašek Samuli Ripatti Mark A Sarzynski Chan Soo Shin Nina Smolej Narančić Dominik Spira Priya Srikanth Elisabeth Steinhagen-Thiessen Yun Ju Sung Karin M A Swart Leena Taittonen Toshiko Tanaka Emmi Tikkanen Nathalie van der Velde Natasja M van Schoor Niek Verweij Alan F Wright Lei Yu Joseph M Zmuda Niina Eklund Terrence Forrester Niels Grarup Anne U Jackson Kati Kristiansson Teemu Kuulasmaa Johanna Kuusisto Peter Lichtner Jian'an Luan Anubha Mahajan Satu Männistö Cameron D Palmer Janina S Ried Robert A Scott Alena Stancáková Peter J Wagner Ayse Demirkan Angela Döring Vilmundur Gudnason Douglas P Kiel Brigitte Kühnel Massimo Mangino Barbara Mcknight Cristina Menni Jeffrey R O'Connell Ben A Oostra Alan R Shuldiner Kijoung Song Liesbeth Vandenput Cornelia M van Duijn Peter Vollenweider Charles C White Michael Boehnke Yvonne Boettcher Richard S Cooper Nita G Forouhi Christian Gieger Harald Grallert Aroon Hingorani Torben Jørgensen Pekka Jousilahti Mika Kivimaki Meena Kumari Markku Laakso Claudia Langenberg Allan Linneberg Amy Luke Colin A Mckenzie Aarno Palotie Oluf Pedersen Annette Peters Konstantin Strauch Bamidele O Tayo Nicholas J Wareham David A Bennett Lars Bertram John Blangero Matthias Blüher Claude Bouchard Harry Campbell Nam H Cho Steven R Cummings Stefan A Czerwinski Ilja Demuth Rahel Eckardt Johan G Eriksson Luigi Ferrucci Oscar H Franco Philippe Froguel Ron T Gansevoort Torben Hansen Tamara B Harris Nicholas Hastie Markku Heliövaara Albert Hofman Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Paul B Knekt Seppo Koskinen Peter Kovacs Terho Lehtimäki Lars Lind Yongmei Liu Eric S Orwoll Clive Osmond Markus Perola Louis Pérusse Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Fernando Rivadeneira Igor Rudan Veikko Salomaa Thorkild I A Sørensen Michael Stumvoll Anke Tönjes Bradford Towne Gregory J Tranah Angelo Tremblay André G Uitterlinden Pim van der Harst Erkki Vartiainen Jorma S Viikari Veronique Vitart Marie-Claude Vohl Henry Völzke Mark Walker Henri Wallaschofski Sarah Wild James F Wilson Loïc Yengo D Timothy Bishop Ingrid B Borecki John C Chambers L Adrienne Cupples Abbas Dehghan Panos Deloukas Ghazaleh Fatemifar Caroline Fox Terrence S Furey Lude Franke Jiali Han David J Hunter Juha Karjalainen Fredrik Karpe Robert C Kaplan Jaspal S Kooner Mark I McCarthy Joanne M Murabito Andrew P Morris Julia A N Bishop Kari E North Claes Ohlsson Ken K Ong Inga Prokopenko J Brent Richards Eric E Schadt Tim D Spector Elisabeth Widén Cristen J Willer Jian Yang Erik Ingelsson Karen L Mohlke Joel N Hirschhorn John Andrew Pospisilik M Carola Zillikens Cecilia Lindgren Tuomas Oskari Kilpeläinen Ruth J F Loos

Nat Commun 2016 Feb 1;7:10495. Epub 2016 Feb 1.

The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/ncomms10495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740398PMC
February 2016

Common variants in DRD2 are associated with sleep duration: the CARe consortium.

Hum Mol Genet 2016 Jan 13;25(1):167-79. Epub 2015 Oct 13.

Division of Sleep and Circadian Disorders and Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA, Center for Human Genetic Research and Department of Anesthesia, Pain, and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114, USA and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1093/hmg/ddv434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690488PMC
January 2016

Genetic associations of periodic limb movements of sleep in the elderly for the MrOS sleep study.

Sleep Med 2015 Nov 11;16(11):1360-1365. Epub 2015 Aug 11.

Departments of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S13899457150087
Publisher Site
http://dx.doi.org/10.1016/j.sleep.2015.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621485PMC
November 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

Mitochondrial DNA sequence variation in multiple sclerosis.

Neurology 2015 Jul 1;85(4):325-30. Epub 2015 Jul 1.

From the California Pacific Medical Center Research Institute (G.J.T.), San Francisco, CA; Department of Neurology (A.S., S.J.C., S.L.H., J.R.O.), University of California, San Francisco; Department of Health Sciences (S.D.), UPO and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Avogadro, Novara, Italy; and Department of Neuro-rehabilitation and INSPE (Institute of Experimental Neurology) (F.M.B.), Scientific Institute San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000001744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520811PMC
July 2015

HLA class II genotypes are not associated with age related macular degeneration in a case-control, population-based study.

Hum Immunol 2015 Mar 7;76(2-3):142-5. Epub 2015 Feb 7.

California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humimm.2015.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476503PMC
March 2015

Weaker circadian activity rhythms are associated with poorer executive function in older women.

Sleep 2014 Dec 1;37(12):2009-16. Epub 2014 Dec 1.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA: San Francisco Veterans Administration, San Francisco, CA: Department of Psychiatry, University of California, San Francisco, CA.

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http://dx.doi.org/10.5665/sleep.4260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548515PMC
December 2014

Genetic modifiers of cognitive maintenance among older adults.

Hum Brain Mapp 2014 Sep 10;35(9):4556-65. Epub 2014 Mar 10.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, California.

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http://dx.doi.org/10.1002/hbm.22494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107001PMC
September 2014

Candidate gene association study of BMI-related loci, weight, and adiposity in old age.

J Gerontol A Biol Sci Med Sci 2013 Jun 16;68(6):661-6. Epub 2012 Nov 16.

Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/gerona/gls227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660116PMC
June 2013

Hip pain while using lower extremity joints and sleep disturbances in elderly white women: results from a cross-sectional analysis.

Arthritis Care Res (Hoboken) 2012 Jul;64(7):1070-8

San Francisco Coordinating Center, California Pacific Medical Center Research Institute, 185 Berry Street, Lobby 5, Suite 5700, San Francisco, CA 94107-1762, USA.

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http://doi.wiley.com/10.1002/acr.21630
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http://dx.doi.org/10.1002/acr.21630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355201PMC
July 2012

Mitochondrial DNA sequence variation and risk of pancreatic cancer.

Cancer Res 2012 Feb 15;72(3):686-95. Epub 2011 Dec 15.

Institute for Human Genetics, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271167PMC
February 2012

Mitochondrial-nuclear epistasis: implications for human aging and longevity.

Authors:
Gregory J Tranah

Ageing Res Rev 2011 Apr 25;10(2):238-52. Epub 2010 Jun 25.

California Pacific Medical Center Research Institute, San Francisco Coordinating Center, UCSF, 94107-1728, USA.

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http://dx.doi.org/10.1016/j.arr.2010.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995012PMC
April 2011

Circadian activity rhythms and mortality: the study of osteoporotic fractures.

J Am Geriatr Soc 2010 Feb 26;58(2):282-91. Epub 2010 Jan 26.

California Pacific Medical Center Research Institute, San Francisco Coordinating Center, UCSF, 185 Berry Street, Lobby 4, Suite 5700, San Francisco, CA 94107, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2009.02674.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938873PMC
February 2010

Solvent exposure and non-Hodgkin lymphoma: no risk in a population-based study in the San Francisco Bay Area.

Cancer Epidemiol Biomarkers Prev 2009 Nov;18(11):3130-2

California Pacific Medical Center Research Institute, University of California-San Francisco, San Francisco, California 94107-1728, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782419PMC
November 2009

Domestic and farm-animal exposures and risk of non-Hodgkin's lymphoma in a population-based study in the San Francisco Bay Area.

Cancer Epidemiol Biomarkers Prev 2008 Sep;17(9):2382-7

California Pacific Medical Center Research Institute, San Francisco Coordinating Center, University of California-San Francisco, San Francisco, CA 94107-1728, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946322PMC
September 2008

p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancer.

Int J Cancer 2006 Oct;119(8):1863-8

Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/ijc.22057DOI Listing
October 2006

Polymorphisms in O6-methylguanine DNA methyltransferase and breast cancer risk.

Pharmacogenet Genomics 2006 Jul;16(7):469-74

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA.

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https://insights.ovid.com/crossref?an=01213011-200607000-000
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http://dx.doi.org/10.1097/01.fpc.0000215065.21718.4cDOI Listing
July 2006

Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.

Mol Carcinog 2005 Sep;44(1):21-30

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mc.20112DOI Listing
September 2005

Prospective study of N-acetyltransferase-2 genotypes, meat intake, smoking and risk of colorectal cancer.

Int J Cancer 2005 Jul;115(4):648-52

Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://doi.wiley.com/10.1002/ijc.20890
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http://dx.doi.org/10.1002/ijc.20890DOI Listing
July 2005

APC Asp1822Val and Gly2502Ser polymorphisms and risk of colorectal cancer and adenoma.

Cancer Epidemiol Biomarkers Prev 2005 Apr;14(4):863-70

Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-04-0687DOI Listing
April 2005

Genetic variants in the UGT1A6 enzyme, aspirin use, and the risk of colorectal adenoma.

J Natl Cancer Inst 2005 Mar;97(6):457-60

Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, GRJ-722, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/jnci/dji066DOI Listing
March 2005

A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma.

Clin Gastroenterol Hepatol 2004 Aug;2(8):704-12

Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

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August 2004

Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study.

Carcinogenesis 2004 Jul 26;25(7):1211-8. Epub 2004 Feb 26.

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/carcin/bgh126DOI Listing
July 2004

XRCC2 and XRCC3 polymorphisms are not associated with risk of colorectal adenoma.

Cancer Epidemiol Biomarkers Prev 2004 Jun;13(6):1090-1

Department of Epidemiology, and Harvard Center for Cancer Prevention, Harvard School of Public Health, Boston, MA, USA.

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June 2004