Gregory J Riggins

Gregory J Riggins

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Gregory J Riggins

Publications by authors named "Gregory J Riggins"

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Correlation of the invasive potential of glioblastoma and expression of caveola-forming proteins caveolin-1 and CAVIN1.

J Neurooncol 2019 Jun 4;143(2):207-220. Epub 2019 Apr 4.

PACE, University of Queensland School of Pharmacy, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.

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http://dx.doi.org/10.1007/s11060-019-03161-8DOI Listing
June 2019

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors.

Gene Ther 2019 Jun 24;26(6):277-286. Epub 2019 May 24.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41434-019-0080-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588423PMC
June 2019

Molecular Study of Thyroid Cancer in World Trade Center Responders.

Int J Environ Res Public Health 2019 05 7;16(9). Epub 2019 May 7.

Institute for Translational Epidemiology and Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.3390/ijerph16091600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539993PMC
May 2019

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma.

Nat Commun 2019 02 26;10(1):943. Epub 2019 Feb 26.

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-019-08905-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391399PMC
February 2019

Mebendazole and radiation in combination increase survival through anticancer mechanisms in an intracranial rodent model of malignant meningioma.

J Neurooncol 2018 Dec 9;140(3):529-538. Epub 2018 Nov 9.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.

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http://link.springer.com/10.1007/s11060-018-03009-7
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http://dx.doi.org/10.1007/s11060-018-03009-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387633PMC
December 2018

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome.

Nature 2018 12 12;564(7735):273-277. Epub 2018 Dec 12.

Ludwig Center and the Howard Hughes Medical Institute at the Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41586-018-0774-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512810PMC
December 2018

Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma.

ACS Chem Biol 2018 11 8;13(11):3206-3216. Epub 2018 Nov 8.

Department of Neurosurgery , Johns Hopkins University School of Medicine , Baltimore , Maryland 21287 , United States.

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http://pubs.acs.org/doi/10.1021/acschembio.8b00864
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http://dx.doi.org/10.1021/acschembio.8b00864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243397PMC
November 2018

Prevention of tumor seeding during needle biopsy by chemotherapeutic-releasing gelatin sticks.

Oncotarget 2017 Apr;8(16):25955-25962

Department of Neurosurgery and Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.oncotarget.com/fulltext/15427
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http://dx.doi.org/10.18632/oncotarget.15427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432229PMC
April 2017

Somatic retrotransposition is infrequent in glioblastomas.

Mob DNA 2016 11;7:22. Epub 2016 Nov 11.

Department of Pathology, Johns Hopkins University School of Medicine, Miller Research Building (MRB) Room 447, 733 North Broadway, Baltimore, MD 21205 USA.

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http://dx.doi.org/10.1186/s13100-016-0077-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105304PMC
November 2016

Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model.

Oncotarget 2016 Oct;7(42):68571-68584

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.18632/oncotarget.11851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356574PMC
October 2016

Suppression of trophoblast cell surface antigen 2 enhances proliferation and migration in liver fluke-associated cholangiocarcinoma.

Ann Hepatol 2016 Jan-Feb;15(1):71-81

Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

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September 2016

Serial analysis of gene expression reveals promising therapeutic targets for liver fluke-associated cholangiocarcinoma.

Asian Pac J Cancer Prev 2012 ;13 Suppl:89-93

Department of Biochemistry, and Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen University, Khon Kaen, Thailand.

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April 2016

Possible involvement of cyclophilin A processing in fumagillin-induced suppression of cholangiocarcinoma cell proliferation.

Asian Pac J Cancer Prev 2012 ;13 Suppl:137-41

Department of Biochemistry, Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen University, Khon Kaen, Thailand.

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April 2016

The anthelmintic drug mebendazole inhibits growth, migration and invasion in gastric cancer cell model.

Toxicol In Vitro 2015 Dec 24;29(8):2038-44. Epub 2015 Aug 24.

Biological Science Institute, Federal University of Para, Augusto Correa Avenue, 01 Guamá, Belém, Pará, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2015.08.007DOI Listing
December 2015

Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model.

Clin Cancer Res 2015 Aug 10;21(15):3462-3470. Epub 2015 Apr 10.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526400PMC
August 2015

Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.

Neuro Oncol 2015 Apr 24;17(4):545-54. Epub 2014 Sep 24.

Department of Neurosurgery (R.-Y.B., G.J.R.), Department of Neurology (V.S.); Department of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland (F.B.); Department of Thoracic Oncology, Memorial Sloan Kettering Cancer Center, New York, New York (C.M.R.).

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http://dx.doi.org/10.1093/neuonc/nou234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483072PMC
April 2015

Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats.

Oncotarget 2015 Mar;6(8):5536-46

Department of Neurology & Neurosurgery, Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467385PMC
http://dx.doi.org/10.18632/oncotarget.3627DOI Listing
March 2015

A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres.

J Neurooncol 2015 Feb 4;121(3):479-87. Epub 2014 Dec 4.

Department of Neurosurgery, School of Medicine, Johns Hopkins University, 1550 Orleans Street, Room 257 CRB2, Baltimore, MD, 21231, USA.

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http://dx.doi.org/10.1007/s11060-014-1672-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648276PMC
February 2015

Repurposing the antihelmintic mebendazole as a hedgehog inhibitor.

Mol Cancer Ther 2015 Jan 5;14(1):3-13. Epub 2014 Nov 5.

Department of Radiation Oncology and Molecular Radiation Sciences, The Kimmel Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-14
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http://dx.doi.org/10.1158/1535-7163.MCT-14-0755-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297232PMC
January 2015

EFFECT OF THE ANTIPARASITIC DRUG MEBENDAZOLE ON CHOLANGIOCARCINOMA GROWTH.

Southeast Asian J Trop Med Public Health 2014 Nov;45(6):1264-70

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November 2014

Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome.

PLoS One 2013 16;8(10):e75945. Epub 2013 Oct 16.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America ; Johns Hopkins Physical Science Oncology Center and Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075945PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797817PMC
July 2014

Activated macrophages promote Wnt/β-catenin signaling in cholangiocarcinoma cells.

Tumour Biol 2014 Jun 19;35(6):5357-67. Epub 2014 Feb 19.

Department of Biochemistry and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand,

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http://dx.doi.org/10.1007/s13277-014-1698-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862210PMC
June 2014

Cancer biomarker discovery for cholangiocarcinoma: the high-throughput approaches.

J Hepatobiliary Pancreat Sci 2014 Jun 12;21(6):388-96. Epub 2014 Feb 12.

Department of Biochemistry, Faculty of Medicine, Khon Kaen University, 123 Mitraparb Road, Khon Kaen, 40002, Thailand; Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

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http://doi.wiley.com/10.1002/jhbp.68
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http://dx.doi.org/10.1002/jhbp.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322866PMC
June 2014

Tumor subtype-specific cancer-testis antigens as potential biomarkers and immunotherapeutic targets for cancers.

Cancer Immunol Res 2014 Apr 25;2(4):371-9. Epub 2013 Nov 25.

Authors' Affiliations: Departments of Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007352PMC
April 2014

Survey of activated kinase proteins reveals potential targets for cholangiocarcinoma treatment.

Tumour Biol 2013 Dec 29;34(6):3519-28. Epub 2013 Jun 29.

Department of Biochemistry and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

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http://dx.doi.org/10.1007/s13277-013-0930-9DOI Listing
December 2013

Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy.

Tumour Biol 2013 Dec 6;34(6):3637-48. Epub 2013 Jul 6.

Department of Biochemistry and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

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http://dx.doi.org/10.1007/s13277-013-0945-2DOI Listing
December 2013

Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI.

Magn Reson Med 2013 Dec 7;70(6):1690-8. Epub 2013 Oct 7.

F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/mrm.24955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857583PMC
December 2013

OTX2 represses myogenic and neuronal differentiation in medulloblastoma cells.

Cancer Res 2012 Nov 17;72(22):5988-6001. Epub 2012 Sep 17.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861240PMC
November 2012

The Hippo signaling pathway and translational opportunities for brain cancers.

CNS Oncol 2012 Nov;1(2):113-5

Ludwig Collaborative Laboratory, Neurosurgery Department, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.2217/cns.12.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696067PMC
November 2012

Yes-associated protein 1 is activated and functions as an oncogene in meningiomas.

Mol Cancer Res 2012 Jul 22;10(7):904-13. Epub 2012 May 22.

Ludwig Collaborative Laboratory, Neurosurgery Department, The Johns Hopkins University, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703097PMC
July 2012

Caveolin-1, caveolae, and glioblastoma.

Neuro Oncol 2012 Jun 16;14(6):679-88. Epub 2012 Apr 16.

University of Queensland School of Pharmacy, PACE, 20 Cornwall St., Woollloongabba QLD 4102, Australia.

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http://dx.doi.org/10.1093/neuonc/nos079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367849PMC
June 2012

Targeting the AKT pathway in glioblastoma.

Curr Pharm Des 2011 ;17(23):2411-20

Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.2174/138161211797249224DOI Listing
May 2012

Establishment and characterization of a primary human chordoma xenograft model.

J Neurosurg 2012 Apr 27;116(4):801-9. Epub 2012 Jan 27.

Department of Neurosurgery, The Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.3171/2011.12.JNS111123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715057PMC
April 2012

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

Curr Opin Oncol 2012 Jan;24(1):83-9

Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/CCO.0b013e32834d816aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612588PMC
January 2012

Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells.

Oncotarget 2011 Nov;2(11):833-49

Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260001PMC
http://dx.doi.org/10.18632/oncotarget.346DOI Listing
November 2011

Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme.

Neuro Oncol 2011 Sep 15;13(9):974-82. Epub 2011 Jul 15.

Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1093/neuonc/nor077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158014PMC
September 2011

PRKAR1A is overexpressed and represents a possible therapeutic target in human cholangiocarcinoma.

Int J Cancer 2011 Jul 3;129(1):34-44. Epub 2010 Nov 3.

Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

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http://dx.doi.org/10.1002/ijc.25646DOI Listing
July 2011

A robust approach to enhance tumor-selective accumulation of nanoparticles.

Oncotarget 2011 Jan-Feb;2(1-2):59-68

The Ludwig Center for Cancer Genetics and Therapeutics, Howard Hughes Medical Institute and Sidney Kimmel Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069713PMC
http://dx.doi.org/10.18632/oncotarget.227DOI Listing
July 2011

Glioblastoma multiforme in the Muir-Torre syndrome.

Clin Neurol Neurosurg 2011 Jun 1;113(5):411-5. Epub 2011 Feb 1.

Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.clineuro.2010.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612635PMC
June 2011

Molecular targeting of glioblastoma: Drug discovery and therapies.

Trends Mol Med 2011 Jun 14;17(6):301-312. Epub 2011 Mar 14.

Departments of Neurosurgery, Johns Hopkins University School of Medicine, CRB II Rm. 257, 1550 Orleans Street, Baltimore, MD 21231, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S147149141100012
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http://dx.doi.org/10.1016/j.molmed.2011.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101015PMC
June 2011

Sodium ion channel mutations in glioblastoma patients correlate with shorter survival.

Mol Cancer 2011 Feb 11;10:17. Epub 2011 Feb 11.

Department of Neurosurgery, Johns Hopkins University Medical School, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1186/1476-4598-10-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050859PMC
February 2011

PVALB, a new Hürthle adenoma diagnostic marker identified through gene expression.

J Clin Endocrinol Metab 2011 Jan 6;96(1):E151-60. Epub 2010 Oct 6.

Genetic Bases of Thyroid Tumor Laboratory, Federal University of São Paulo, São Paulo, SP, Brazil.

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http://dx.doi.org/10.1210/jc.2010-1318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038489PMC
January 2011

ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence.

BMC Cancer 2011 Jan 11;11:11. Epub 2011 Jan 11.

Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics and Division of Endocrinology, Universidade Federal de São Paulo, SP, Brazil.

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http://dx.doi.org/10.1186/1471-2407-11-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032749PMC
January 2011

Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas.

Neuro Oncol 2010 Jul 5;12(7):655-63. Epub 2010 Feb 5.

Department of Neurosurgery, Johns Hopkins University, CRB II Rm. 257, 1550 Orleans Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1093/neuonc/nop062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940451PMC
July 2010

Establishment of a human glioblastoma stemlike brainstem rodent tumor model.

J Neurosurg Pediatr 2010 Jul;6(1):92-7

Departments of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.3171/2010.3.PEDS09366DOI Listing
July 2010

A survey of glioblastoma genomic amplifications and deletions.

J Neurooncol 2010 Jan 17;96(2):169-79. Epub 2009 Jul 17.

Department of Neurosurgery, Johns Hopkins University, CRB II Rm. 257, 1550 Orleans Street, Baltimore, MD 21231, USA.

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http://link.springer.com/10.1007/s11060-009-9959-4
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http://dx.doi.org/10.1007/s11060-009-9959-4DOI Listing
January 2010

Glioblastoma cell growth is suppressed by disruption of Fibroblast Growth Factor pathway signaling.

J Neurooncol 2009 Sep 2;94(3):359-66. Epub 2009 Apr 2.

Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1007/s11060-009-9885-5DOI Listing
September 2009

Identification of microbial DNA in human cancer.

BMC Med Genomics 2009 May 8;2:22. Epub 2009 May 8.

Preston Robert Tisch Brain Tumor Center, Pediatric Brain Tumor Foundation Institute, Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1186/1755-8794-2-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685141PMC
May 2009

Down-regulation of NR4A1 in follicular thyroid carcinomas is restored following lithium treatment.

Clin Endocrinol (Oxf) 2009 Mar 22;70(3):475-83. Epub 2008 Aug 22.

Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology, Federal University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1111/j.1365-2265.2008.03349.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742303PMC
March 2009

Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.

Mol Cancer Ther 2009 Feb 10;8(2):386-93. Epub 2009 Feb 10.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498795PMC
February 2009

Coexpression of neuronatin splice forms promotes medulloblastoma growth.

Neuro Oncol 2008 Oct 13;10(5):716-24. Epub 2008 Aug 13.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231 USA.

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http://dx.doi.org/10.1215/15228517-2008-038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666248PMC
October 2008

Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasion.

Endocr Relat Cancer 2008 Sep 17;15(3):787-99. Epub 2008 Jun 17.

Department of Morphology and Genetics, Federal University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1677/ERC-08-0079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742300PMC
September 2008

Methionine aminopeptidase 2 over-expressed in cholangiocarcinoma: potential for drug target.

Acta Oncol 2007 ;46(3):378-85

Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

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http://dx.doi.org/10.1080/02841860600871061DOI Listing
October 2007

Molecular profiling of matched samples identifies biomarkers of papillary thyroid carcinoma lymph node metastasis.

Cancer Res 2007 Aug;67(16):7885-92

Department of Neurosurgery, Johns Hopkins University Medical School, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4771DOI Listing
August 2007

A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII.

Mol Cancer 2007 Apr 16;6:30. Epub 2007 Apr 16.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-6-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855066PMC
April 2007

PLXDC1 (TEM7) is identified in a genome-wide expression screen of glioblastoma endothelium.

J Neurooncol 2007 Feb 20;81(3):241-8. Epub 2006 Sep 20.

Department of Neurosurgery, Johns Hopkins University Medical School, CRB II Rm. 257 , 1550 Orleans Street, Baltimore, MD, 21231, USA.

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http://link.springer.com/10.1007/s11060-006-9227-9
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http://dx.doi.org/10.1007/s11060-006-9227-9DOI Listing
February 2007

Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.

Hum Mutat 2006 Oct;27(10):1060-1

The Ludwig Center for Cancer Genetics and Therapeutics, The Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1002/humu.9452DOI Listing
October 2006

PIK3CA gene mutations in pediatric and adult glioblastoma multiforme.

Mol Cancer Res 2006 Oct;4(10):709-14

Department of Neurosurgery, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II, Room 257, Baltimore, MD 21231, USA.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-06
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http://dx.doi.org/10.1158/1541-7786.MCR-06-0172DOI Listing
October 2006

Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility.

J Biol Chem 2006 Jun 9;281(24):16681-90. Epub 2006 Mar 9.

Laboratory of Immunology, NIA Intramural Research Program, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1074/jbc.M600223200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271047PMC
June 2006

Diagnosis of suspicious thyroid nodules using four protein biomarkers.

Clin Cancer Res 2006 Jun;12(11 Pt 1):3311-8

Department of Neurosurgery, Johns Hopkins University Medical School, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-2226DOI Listing
June 2006

Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme.

Clin Cancer Res 2006 Apr;12(7 Pt 1):1970-82

Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-2797DOI Listing
April 2006

Meningioma transcript profiles reveal deregulated Notch signaling pathway.

Cancer Res 2005 Jun;65(12):5070-5

Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-0240DOI Listing
June 2005

Genomic amplification of orthodenticle homologue 2 in medulloblastomas.

Cancer Res 2005 Feb;65(3):703-7

Departments of Neurosurgery and Pathology, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Baltimore, MD 21224, USA.

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February 2005

The impact of SNPs on the interpretation of SAGE and MPSS experimental data.

Nucleic Acids Res 2004 23;32(20):6104-10. Epub 2004 Nov 23.

Laboratory of Molecular Biology, Ludwig Institute for Cancer Research, 01509-010, São Paulo, SP, Brazil.

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http://dx.doi.org/10.1093/nar/gkh937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534621PMC
December 2004

Splicing factors are differentially expressed in tumors.

Genet Mol Res 2004 Dec 30;3(4):512-20. Epub 2004 Dec 30.

Ludwig Institute for Cancer Research, São Paulo Branch, São Paulo, SP, Brazil.

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December 2004

Identification of astrocytoma associated genes including cell surface markers.

BMC Cancer 2004 Jul 21;4:39. Epub 2004 Jul 21.

Department of Neurosurgery, Mason F, Lord Bldg, Center Tower, 5th Floor, 5200 Eastern Avenue, Baltimore MD 21224, USA.

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http://dx.doi.org/10.1186/1471-2407-4-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC497045PMC
July 2004

Oncogenomics and the development of new cancer therapies.

Nature 2004 May;429(6990):469-74

Department of Mammalian Genomics, The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 2085, USA.

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http://www.nature.com/articles/nature02627
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May 2004

High frequency of mutations of the PIK3CA gene in human cancers.

Science 2004 Apr 11;304(5670):554. Epub 2004 Mar 11.

Sidney Kimmel Comprehensive Cancer Center, Howard Hughes Medical Institute, The Johns Hopkins University Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1126/science.1096502DOI Listing
April 2004

A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression.

J Clin Invest 2004 Apr;113(8):1234-42

Laboratory of Molecular Endocrinology, Division of Endocrinology, Department of Medicine, Federal University of São Paulo, Brazil.

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http://dx.doi.org/10.1172/JCI19617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC385398PMC
April 2004