Gregory J Kirkner

Gregory J Kirkner

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Gregory J Kirkner

Gregory J Kirkner

Publications by authors named "Gregory J Kirkner"

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Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.

Cancer Causes Control 2010 Mar;21(3):331-45

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s10552-009-9464-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570978PMC
March 2010

Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.

J Clin Oncol 2009 Sep 24;27(27):4591-8. Epub 2009 Aug 24.

Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 44 Binney St, Room JF-215C, Boston, MA 02115 USA.

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http://ascopubs.org/doi/10.1200/JCO.2009.22.8858
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http://dx.doi.org/10.1200/JCO.2009.22.8858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754907PMC
September 2009

p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.

Cancer Epidemiol Biomarkers Prev 2009 Sep 1;18(9):2513-21. Epub 2009 Sep 1.

Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-09-0451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758547PMC
September 2009

A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.

Am J Gastroenterol 2009 Aug 9;104(8):2047-56. Epub 2009 Jun 9.

Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, 44 Binney St, Room JF-215C, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ajg.2009.281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866652PMC
August 2009

Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.

Neoplasia 2009 May;11(5):418-25

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671854PMC
http://dx.doi.org/10.1593/neo.09154DOI Listing
May 2009

Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.

Gastroenterology 2009 Apr 24;136(4):1242-50. Epub 2008 Dec 24.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, and Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663601PMC
April 2009

PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.

J Clin Oncol 2009 Mar 23;27(9):1477-84. Epub 2009 Feb 23.

Department of Medical Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 44 Binney St, Room JF-215C, Boston, MA 02115 USA.

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http://ascopubs.org/doi/10.1200/JCO.2008.18.6544
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http://dx.doi.org/10.1200/JCO.2008.18.6544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659340PMC
March 2009

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.

Gut 2009 Jan 2;58(1):90-6. Epub 2008 Oct 2.

Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 USA.

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http://gut.bmj.com/cgi/doi/10.1136/gut.2008.155473
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http://dx.doi.org/10.1136/gut.2008.155473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679586PMC
January 2009

Cohort study of fatty acid synthase expression and patient survival in colon cancer.

J Clin Oncol 2008 Dec 27;26(35):5713-20. Epub 2008 Oct 27.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1200/JCO.2008.18.2675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630484PMC
December 2008

A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer.

J Natl Cancer Inst 2008 Dec 25;100(23):1734-8. Epub 2008 Nov 25.

Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/jnci/djn359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639290PMC
December 2008

WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.

Mod Pathol 2008 Feb 14;21(2):150-8. Epub 2007 Dec 14.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/modpathol.3800996DOI Listing
February 2008

Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.

Gut 2007 Nov 5;56(11):1564-71. Epub 2007 Mar 5.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 75 Francis St, BWH Pathology, Boston, MA 02115, USA.

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http://dx.doi.org/10.1136/gut.2007.119750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095664PMC
November 2007

Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.

J Mol Diagn 2007 Jul;9(3):305-14

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899428PMC
http://dx.doi.org/10.2353/jmoldx.2007.060170DOI Listing
July 2007

Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.

Hum Pathol 2007 Jun 12;38(6):842-9. Epub 2007 Mar 12.

Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.humpath.2006.11.018DOI Listing
June 2007

TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.

Hum Pathol 2007 Apr 31;38(4):614-20. Epub 2007 Jan 31.

Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.humpath.2006.10.005DOI Listing
April 2007

Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.

Mod Pathol 2007 Jan 3;20(1):15-22. Epub 2006 Nov 3.

Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.3800709DOI Listing
January 2007

CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.

J Mol Diagn 2006 Nov;8(5):582-8

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876166PMC
http://dx.doi.org/10.2353/jmoldx.2006.060082DOI Listing
November 2006

Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.

Mod Pathol 2006 Aug 12;19(8):1083-90. Epub 2006 May 12.

Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/modpathol.3800618DOI Listing
August 2006

Urban, rural, and regional variations in physical activity.

J Rural Health 2005 ;21(3):239-44

Centers for Disease Control and Prevention, Division of Nutrition and Physical Activity, Physical Activity and Health Branch, Atlanta, GA 30341, USA.

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November 2005

Plasma vitamin D metabolites and risk of colorectal cancer in women.

Cancer Epidemiol Biomarkers Prev 2004 Sep;13(9):1502-8

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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September 2004

Metabolic predictors of 5-year change in weight and waist circumference in a triethnic population: the insulin resistance atherosclerosis study.

Am J Epidemiol 2003 Apr;157(7):592-601

Department of Epidemiology and Biostatistics, School of Public Health, University of South Carolina, Columbia, SC 29208, USA.

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http://dx.doi.org/10.1093/aje/kwg022DOI Listing
April 2003