Gregory J Hannon

Gregory J Hannon

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Gregory J Hannon

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Specialization of the nuclear export family protein Nxf3 for piRNA precursor export.

Genes Dev 2019 09 15;33(17-18):1208-1220. Epub 2019 Aug 15.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.

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http://dx.doi.org/10.1101/gad.328690.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719614PMC
September 2019

Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery.

Genes Dev 2019 07 23;33(13-14):844-856. Epub 2019 May 23.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.

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http://dx.doi.org/10.1101/gad.325662.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601507PMC
July 2019

lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation.

Cell Rep 2019 Apr;27(3):719-729.e6

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, UK; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA; New York Genome Center, New York, NY 10013, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.03.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484780PMC
April 2019

piRNA-Guided Genome Defense: From Biogenesis to Silencing.

Annu Rev Genet 2018 11;52:131-157

Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom; email: ,

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http://dx.doi.org/10.1146/annurev-genet-120417-031441DOI Listing
November 2018

Corrigendum to "GoldCLIP: Gel-omitted Ligation-dependent CLIP" [Genomics Proteomics Bioinformatics 16 (2) (2018) 136-143].

Genomics Proteomics Bioinformatics 2018 06 20;16(3):221-222. Epub 2018 Jul 20.

CAS Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076381PMC
June 2018

Corrigendum to "GoldCLIP: Gel-omitted Ligation-dependent CLIP" [Genomics Proteomics Bioinformatics 16 (2) (2018) 136-143].

Genomics Proteomics Bioinformatics 2018 06 20;16(3):221-222. Epub 2018 Jul 20.

CAS Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076381PMC
June 2018

GoldCLIP: Gel-omitted Ligation-dependent CLIP.

Genomics Proteomics Bioinformatics 2018 04 28;16(2):136-143. Epub 2018 Apr 28.

CAS Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2018.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112358PMC
April 2018

Evolutionary expansion of DNA hypomethylation in the mammalian germline genome.

Genome Res 2018 02 19;28(2):145-158. Epub 2017 Dec 19.

Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1101/gr.225896.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793779PMC
February 2018

A Model for Epigenetic Inhibition via Transvection in the Mouse.

Genetics 2017 09 10;207(1):129-138. Epub 2017 Jul 10.

Cell Biology Department, Emory University, Atlanta, Georgia 30322

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http://dx.doi.org/10.1534/genetics.117.201913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586367PMC
September 2017

BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.

Stem Cell Reports 2017 07 1;9(1):23-31. Epub 2017 Jun 1.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.04.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783326PMC
July 2017

A CRISPR Resource for Individual, Combinatorial, or Multiplexed Gene Knockout.

Mol Cell 2017 Jul;67(2):348-354.e4

Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK; Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA; New York Genome Center, 101 6th Avenue, New York, NY 10013, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.06.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526787PMC
July 2017

lncRNAs in development and disease: from functions to mechanisms.

Open Biol 2017 07;7(7)

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, New York, NY 11724, USA

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http://rsob.royalsocietypublishing.org/lookup/doi/10.1098/rs
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http://dx.doi.org/10.1098/rsob.170121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541349PMC
July 2017

Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway.

Genes Dev 2016 07;30(14):1623-35

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom; The New York Genome Center, New York, New York 10011, USA;

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http://dx.doi.org/10.1101/gad.284927.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973292PMC
July 2016

One Loop to Rule Them All: The Ping-Pong Cycle and piRNA-Guided Silencing.

Trends Biochem Sci 2016 04 19;41(4):324-337. Epub 2016 Jan 19.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, CB2 0RE, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680004150025
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http://dx.doi.org/10.1016/j.tibs.2015.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819955PMC
April 2016

Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation.

Cell Stem Cell 2016 Feb 6;18(2):276-90. Epub 2015 Dec 6.

Howard Hughes Medical Institute and Kimmel Center for Biology and Medicine of the Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744108PMC
February 2016

A Happy 3' Ending to the piRNA Maturation Story.

Cell 2016 Feb;164(5):838-40

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, CB2 0RE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.02.012DOI Listing
February 2016

Inducing RNAi in Caenorhabditis elegans by Injection of dsRNA.

Cold Spring Harb Protoc 2016 Jan 4;2016(1):pdb.prot086306. Epub 2016 Jan 4.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.prot08630
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http://dx.doi.org/10.1101/pdb.prot086306DOI Listing
January 2016

Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization.

Proc Natl Acad Sci U S A 2015 Oct 5;112(42):12974-9. Epub 2015 Oct 5.

Department of Genetics, Harvard Medical School, Boston, MA 02115, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115

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http://dx.doi.org/10.1073/pnas.1517729112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620889PMC
October 2015

Panoramix enforces piRNA-dependent cotranscriptional silencing.

Science 2015 Oct;350(6258):339-42

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK. The New York Genome Center, 101 Avenue of the Americas, New York, NY 10013, USA.

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http://dx.doi.org/10.1126/science.aab0700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722808PMC
October 2015

RNF17 blocks promiscuous activity of PIWI proteins in mouse testes.

Genes Dev 2015 Jul 26;29(13):1403-15. Epub 2015 Jun 26.

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, New York 11724, USA; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, New York 11724, USA; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.

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http://dx.doi.org/10.1101/gad.265215.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511215PMC
July 2015

ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation.

Nat Cell Biol 2015 May 27;17(5):689-96. Epub 2015 Apr 27.

Howard Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/ncb3165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573567PMC
May 2015

An epigenetic memory of pregnancy in the mouse mammary gland.

Cell Rep 2015 May 7;11(7):1102-9. Epub 2015 May 7.

Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439279PMC
May 2015

piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis.

Genes Dev 2015 May;29(10):1032-44

Howard Hughes Medical Institute, Cold Spring Harbor, New York 11724, USA; Watson School of Biological Sciences, Cold Spring Harbor, New York 11724, USA; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK;

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http://dx.doi.org/10.1101/gad.260455.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441051PMC
May 2015

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.

Nature 2015 Apr 8;520(7547):358-62. Epub 2015 Apr 8.

1] Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA [2] CRUK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robininson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1038/nature14403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634366PMC
April 2015

Essential Role for endogenous siRNAs during meiosis in mouse oocytes.

PLoS Genet 2015 Feb 19;11(2):e1005013. Epub 2015 Feb 19.

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335007PMC
February 2015

A computational algorithm to predict shRNA potency.

Mol Cell 2014 Dec 26;56(6):796-807. Epub 2014 Nov 26.

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1016/j.molcel.2014.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272634PMC
December 2014

MicroRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development.

Cancer Res 2014 Nov 12;74(22):6648-60. Epub 2014 Sep 12.

Innovation Center for Cell Biology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, Anhui, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370193PMC
November 2014

Starvation-induced transgenerational inheritance of small RNAs in C. elegans.

Cell 2014 Jul 10;158(2):277-287. Epub 2014 Jul 10.

Columbia University Medical Center, Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.cell.2014.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377509PMC
July 2014

Two waves of de novo methylation during mouse germ cell development.

Genes Dev 2014 Jul;28(14):1544-9

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA;

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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.244350.114
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http://dx.doi.org/10.1101/gad.244350.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102761PMC
July 2014

Inducing RNAi in Drosophila cells by soaking with dsRNA.

Cold Spring Harb Protoc 2014 May 1;2014(5). Epub 2014 May 1.

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http://dx.doi.org/10.1101/pdb.prot080747DOI Listing
May 2014

De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements.

Genome Res 2013 Oct 28;23(10):1601-14. Epub 2013 Jun 28.

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA;

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http://dx.doi.org/10.1101/gr.157271.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787258PMC
October 2013

Patient-derived tumor xenografts: transforming clinical samples into mouse models.

Cancer Res 2013 Sep 3;73(17):5315-9. Epub 2013 Jun 3.

New York University Cancer Institute; and Watson School of Biological Sciences, Howard Hughes Medical Institute Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY 11742, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766500PMC
September 2013

Dicer-2 processes diverse viral RNA species.

PLoS One 2013 12;8(2):e55458. Epub 2013 Feb 12.

Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055458PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570552PMC
August 2013

Minotaur is critical for primary piRNA biogenesis.

RNA 2013 Aug 20;19(8):1064-77. Epub 2013 Jun 20.

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NewYork 11724, USA.

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http://dx.doi.org/10.1261/rna.039669.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708527PMC
August 2013

Packaging shRNA retroviruses.

Cold Spring Harb Protoc 2013 Aug 1;2013(8):734-7. Epub 2013 Aug 1.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.prot07644
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http://dx.doi.org/10.1101/pdb.prot076448DOI Listing
August 2013

Infection of mammalian cells with retroviral shRNAs.

Cold Spring Harb Protoc 2013 Aug 1;2013(8):732-3. Epub 2013 Aug 1.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.prot07645
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http://dx.doi.org/10.1101/pdb.prot076455DOI Listing
August 2013

A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene space in Arabidopsis.

Plant Cell 2013 Aug 16;25(8):2848-63. Epub 2013 Aug 16.

Division of Biological Sciences, Cell and Developmental Biology Section, University of California San Diego, La Jolla, California 92093-0116.

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http://dx.doi.org/10.1105/tpc.113.112805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784584PMC
August 2013

Creating an miR30-based shRNA vector.

Cold Spring Harb Protoc 2013 Jul 1;2013(7):631-5. Epub 2013 Jul 1.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.prot07585
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http://dx.doi.org/10.1101/pdb.prot075853DOI Listing
July 2013

Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.

Genes Dev 2013 Jul 3;27(14):1624-32. Epub 2013 Jul 3.

Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.215939.113
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http://dx.doi.org/10.1101/gad.215939.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731550PMC
July 2013

A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway.

Mol Cell 2013 Jun 9;50(5):749-61. Epub 2013 May 9.

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765130028
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http://dx.doi.org/10.1016/j.molcel.2013.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724427PMC
June 2013

A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila.

Mol Cell 2013 Jun 9;50(5):736-48. Epub 2013 May 9.

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765130028
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http://dx.doi.org/10.1016/j.molcel.2013.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724422PMC
June 2013

The making of a slicer: activation of human Argonaute-1.

Cell Rep 2013 Jun 6;3(6):1901-9. Epub 2013 Jun 6.

W.M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.05.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769929PMC
June 2013

Dnmt2-dependent methylomes lack defined DNA methylation patterns.

Proc Natl Acad Sci U S A 2013 May 2;110(21):8627-31. Epub 2013 May 2.

Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1306723110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666705PMC
May 2013

Molecular hierarchy of mammary differentiation yields refined markers of mammary stem cells.

Proc Natl Acad Sci U S A 2013 Apr 11;110(18):7123-30. Epub 2013 Apr 11.

Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1073/pnas.1303919110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645536PMC
April 2013

Dogma derailed: the many influences of RNA on the genome.

Mol Cell 2013 Mar;49(5):783-94

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1016/j.molcel.2013.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825098PMC
March 2013

The piRNA pathway in flies: highlights and future directions.

Curr Opin Genet Dev 2013 Feb 11;23(1):44-52. Epub 2013 Jan 11.

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States.

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http://dx.doi.org/10.1016/j.gde.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621807PMC
February 2013

Multiple roles for Piwi in silencing Drosophila transposons.

Genes Dev 2013 Feb 7;27(4):400-12. Epub 2013 Feb 7.

Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.209767.112
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http://dx.doi.org/10.1101/gad.209767.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589557PMC
February 2013

Site identification in high-throughput RNA-protein interaction data.

Bioinformatics 2012 Dec 28;28(23):3013-20. Epub 2012 Sep 28.

Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1093/bioinformatics/bts569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509493PMC
December 2012

Inducing RNAi in C. elegans by feeding with dsRNA-expressing E. coli.

Cold Spring Harb Protoc 2012 Dec 1;2012(12). Epub 2012 Dec 1.

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http://dx.doi.org/10.1101/pdb.prot072348DOI Listing
December 2012

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.

Nature 2012 Nov 14;491(7423):279-83. Epub 2012 Oct 14.

W. M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1038/nature11502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493678PMC
November 2012

Preparation of small RNA libraries for high-throughput sequencing.

Cold Spring Harb Protoc 2012 Oct 1;2012(10):1067-77. Epub 2012 Oct 1.

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http://dx.doi.org/10.1101/pdb.prot071431DOI Listing
October 2012

shutdown is a component of the Drosophila piRNA biogenesis machinery.

RNA 2012 Aug 2;18(8):1446-57. Epub 2012 Jul 2.

Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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http://rnajournal.cshlp.org/cgi/doi/10.1261/rna.034405.112
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http://dx.doi.org/10.1261/rna.034405.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404366PMC
August 2012

The structure of human argonaute-2 in complex with miR-20a.

Cell 2012 Jul 7;150(1):100-10. Epub 2012 Jun 7.

W. M. Keck Structural Biology Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1016/j.cell.2012.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464090PMC
July 2012

Genomic landscape of human allele-specific DNA methylation.

Proc Natl Acad Sci U S A 2012 May 20;109(19):7332-7. Epub 2012 Apr 20.

Molecular and Computational Biology, Department of Biological Sciences, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1073/pnas.1201310109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358917PMC
May 2012

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

J Virol 2012 Apr 8;86(8):4151-7. Epub 2012 Feb 8.

Department of Immunology, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1128/JVI.05303-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318639PMC
April 2012

An alternative mode of microRNA target recognition.

Nat Struct Mol Biol 2012 Feb 12;19(3):321-7. Epub 2012 Feb 12.

Laboratory of Neuro-Oncology, The Rockefeller University, Howard Hughes Medical Institute, New York, New York, USA.

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http://dx.doi.org/10.1038/nsmb.2230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541676PMC
February 2012

Production of artificial piRNAs in flies and mice.

RNA 2012 Jan 17;18(1):42-52. Epub 2011 Nov 17.

Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1261/rna.029769.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261743PMC
January 2012

Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy.

Proc Natl Acad Sci U S A 2012 Jan 4;109(3):869-74. Epub 2012 Jan 4.

Department of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1119873109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271875PMC
January 2012

Cell-type-based analysis of microRNA profiles in the mouse brain.

Neuron 2012 Jan;73(1):35-48

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA; Genetics Program, State University of New York, Stony Brook, NY 11790, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089662731101009
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http://dx.doi.org/10.1016/j.neuron.2011.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270494PMC
January 2012

Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles.

Genome Res 2011 Sep 17;21(9):1462-77. Epub 2011 Jun 17.

Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.121426.111
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http://dx.doi.org/10.1101/gr.121426.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166831PMC
September 2011

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila.

Development 2011 Sep 10;138(18):4039-50. Epub 2011 Aug 10.

HHMI and Kimmel Center for Biology and Medicine at Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1242/dev.069187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160098PMC
September 2011

piRNA production requires heterochromatin formation in Drosophila.

Curr Biol 2011 Aug 4;21(16):1373-9. Epub 2011 Aug 4.

Department of Cell Biology, Howard Hughes Medical Institute and Kimmel Center for Biology and Medicine, Skirball Institute, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.cub.2011.06.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205116PMC
August 2011