Publications Authored by Gregory D Jenkins

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2.

Clin Pharmacol Ther 2019 Jul 18;106(1):219-227. Epub 2019 Mar 18.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://doi.wiley.com/10.1002/cpt.1359	Publisher Site
http://dx.doi.org/10.1002/cpt.1359	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612579	PMC

July 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:

Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Jun 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9	Publisher Site
http://dx.doi.org/10.1007/s00401-019-01962-9	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145	PMC

June 2019

Gut microbiome meta-analysis reveals dysbiosis is independent of body mass index in predicting risk of obesity-associated CRC.

Authors:

K Leigh Greathouse James Robert White R Noah Padgett Brittany G Perrotta Gregory D Jenkins Nicholas Chia Jun Chen

BMJ Open Gastroenterol 2019 28;6(1):e000247. Epub 2019 Feb 28.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, New York, USA.

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http://dx.doi.org/10.1136/bmjgast-2018-000247	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398873	PMC

February 2019

Association of mitochondrial DNA copy number with self-rated health status.

Authors:

Paul Y Takahashi Gregory D Jenkins Benjamin P Welkie Shannon K McDonnell Jared M Evans James R Cerhan Janet E Olson Stephen N Thibodeau Mine S Cicek Euijung Ryu

Appl Clin Genet 2018 25;11:121-127. Epub 2018 Oct 25.

Department of health sciences research.

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http://dx.doi.org/10.2147/TACG.S167640	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207265	PMC

October 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:

Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181	PMC

June 2018

Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota.

Authors:

Shoko Edogawa Stephanie A Peters Gregory D Jenkins Sakteesh V Gurunathan Wendy J Sundt Stephen Johnson Ryan J Lennon Roy B Dyer Michael Camilleri Purna C Kashyap Gianrico Farrugia Jun Chen Ravinder J Singh Madhusudan Grover

FASEB J 2018 Jun 13:fj201800560R. Epub 2018 Jun 13.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1096/fj.201800560R	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219825	PMC

June 2018

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.

Authors:

Junmei Cairns Brooke L Fridley Gregory D Jenkins Yongxian Zhuang Jia Yu Liewei Wang

EMBO Rep 2018 03 15;19(3). Epub 2018 Jan 15.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA

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http://dx.doi.org/10.15252/embr.201744767	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835844	PMC

March 2018

A Genome-Wide Search for Bipolar Disorder Risk Loci Modified by Mitochondrial Genome Variation.

Authors:

Euijung Ryu Malik Nassan Gregory D Jenkins Sebastian M Armasu Ana Andreazza Susan L McElroy Marquis P Vawter Mark A Frye Joanna M Biernacka

Mol Neuropsychiatry 2018 Feb 28;3(3):125-134. Epub 2017 Oct 28.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1159/000464444	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836158	PMC

February 2018

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.

Transl Psychiatry 2018 01 10;8(1):10. Epub 2018 Jan 10.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41398-017-0056-8	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802574	PMC

January 2018

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.

Authors:

Tanda M Dudenkov James N Ingle Aman U Buzdar Mark E Robson Michiaki Kubo Irada Ibrahim-Zada Anthony Batzler Gregory D Jenkins Tracy L Pietrzak Erin E Carlson Poulami Barman Matthew P Goetz Donald W Northfelt Alvaro Moreno-Aspita Clark V Williard Krishna R Kalari Yusuke Nakamura Liewei Wang Richard M Weinshilboum

Breast Cancer Res Treat 2017 Jul 20;164(1):189-199. Epub 2017 Apr 20.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s10549-017-4243-3	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600471	PMC

July 2017

Comparison of Whole-Genome Sequencing Methods for Analysis of Three Methicillin-Resistant Staphylococcus aureus Outbreaks.

Authors:

Scott A Cunningham Nicholas Chia Patricio R Jeraldo Daniel J Quest Julie A Johnson Dave J Boxrud Angela J Taylor Jun Chen Gregory D Jenkins Travis M Drucker Heidi Nelson Robin Patel

J Clin Microbiol 2017 06 12;55(6):1946-1953. Epub 2017 Apr 12.

Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA

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http://dx.doi.org/10.1128/JCM.00029-17	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442552	PMC

June 2017

Combining a nontargeted and targeted metabolomics approach to identify metabolic pathways significantly altered in polycystic ovary syndrome.

Authors:

Alice Y Chang Antigoni Z Lalia Gregory D Jenkins Tumpa Dutta Rickey E Carter Ravinder J Singh K Sreekumaran Nair

Metabolism 2017 06 8;71:52-63. Epub 2017 Mar 8.

Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.metabol.2017.03.002	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520539	PMC

June 2017

Increased risk of hospitalization for ultrarapid metabolizers of cytochrome P450 2D6.

Authors:

Paul Y Takahashi Euijung Ryu Jyotishman Pathak Gregory D Jenkins Anthony Batzler Matthew A Hathcock John Logan Black Janet E Olson James R Cerhan Suzette J Bielinski

Pharmgenomics Pers Med 2017 14;10:39-47. Epub 2017 Feb 14.

Department of Health Sciences Research.

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http://dx.doi.org/10.2147/PGPM.S114211	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317339	PMC

February 2017

A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model.

Authors:

Malik Nassan Qingqin Li Paul E Croarkin Wenan Chen Colin L Colby Marin Veldic Susan L McElroy Gregory D Jenkins Euijung Ryu Julie M Cunningham Marion Leboyer Mark A Frye Joanna M Biernacka

J Affect Disord 2017 Jan 30;208:120-129. Epub 2016 Sep 30.

Department of Psychiatry & Psychology, Mayo Clinic Depression Center, Mayo Clinic, Rochester, MN, United States; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2016.09.049	DOI Listing

January 2017

Mitochondrial DNA sequence data reveals association of haplogroup U with psychosis in bipolar disorder.

Authors:

Mark A Frye Euijung Ryu Malik Nassan Gregory D Jenkins Ana C Andreazza Jared M Evans Susan L McElroy Devin Oglesbee W Edward Highsmith Joanna M Biernacka

J Psychiatr Res 2017 01 30;84:221-226. Epub 2016 Sep 30.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2016.09.027	DOI Listing

January 2017

Accumulating evidence for a role of TCF7L2 variants in bipolar disorder with elevated body mass index.

Authors:

Alfredo B Cuellar-Barboza Stacey J Winham Susan L McElroy Jennifer R Geske Gregory D Jenkins Colin L Colby Miguel L Prieto Euijung Ryu Julie M Cunningham Mark A Frye Joanna M Biernacka

Bipolar Disord 2016 Mar 2;18(2):124-35. Epub 2016 Mar 2.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1111/bdi.12368	DOI Listing

March 2016

Modeling X Chromosome Data Using Random Forests: Conquering Sex Bias.

Authors:

Stacey J Winham Gregory D Jenkins Joanna M Biernacka

Genet Epidemiol 2016 Feb 7;40(2):123-32. Epub 2015 Dec 7.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1002/gepi.21946	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724236	PMC

February 2016

Pharmacogenomics of estrogens on changes in carotid artery intima-medial thickness and coronary arterial calcification: Kronos Early Estrogen Prevention Study.

Authors:

Virginia M Miller Gregory D Jenkins Joanna M Biernacka John A Heit Gordon S Huggins Howard N Hodis Matthew J Budoff Rogerio A Lobo Hugh S Taylor JoAnn E Manson Dennis M Black Frederick Naftolin S Mitchell Harman Mariza de Andrade

Physiol Genomics 2016 Jan 27;48(1):33-41. Epub 2015 Oct 27.

Department of Health Sciences Research (Divisions of Biomedical Statistics and Informatics and Epidemiology), Mayo Clinic, Rochester, Minnesota;

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http://physiolgenomics.physiology.org/content/physiolgenomic	Web Search
http://physiolgenomics.physiology.org/content/physiolgenomic	Web Search
http://physiolgenomics.physiology.org/lookup/doi/10.1152/phy	Publisher Site
http://dx.doi.org/10.1152/physiolgenomics.00029.2015	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757027	PMC

January 2016

Genome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.

Authors:

Lata Chauhan Gregory D Jenkins Neha Bhise Tanya Feldberg Taraswi Mitra-Ghosh Brooke L Fridley Jatinder K Lamba

BMC Genomics 2015 Jun 30;16:483. Epub 2015 Jun 30.

Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1186/s12864-015-1614-1	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485866	PMC

June 2015

Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites.

Authors:

Naveen L Pereira Nirubol Tosakulwong Christopher G Scott Gregory D Jenkins Naresh Prodduturi Yubo Chai Timothy M Olson Richard J Rodeheffer Margaret M Redfield Richard M Weinshilboum John C Burnett

Circ Cardiovasc Genet 2015 Feb 1;8(1):141-9. Epub 2014 Dec 1.

From the Division of Cardiovascular Diseases, Department of Internal Medicine (N.L.P., T.M.O., R.J.R., M.M.R., J.C.B.), Department of Biomedical Statistics and Informatics (N.T., C.G.S, G.D.J., N.P.), and Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (N.L.P., R.M.W.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000624	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387792	PMC

February 2015

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Authors:

Mohan Liu Paul E Goss James N Ingle Michiaki Kubo Yoichi Furukawa Anthony Batzler Gregory D Jenkins Erin E Carlson Yusuke Nakamura Daniel J Schaid Judy-Anne W Chapman Lois E Shepherd Matthew J Ellis Sundeep Khosla Liewei Wang Richard M Weinshilboum

Mol Endocrinol 2014 Oct 22;28(10):1740-51. Epub 2014 Aug 22.

Division of Clinical Pharmacology (M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics; Departments of Oncology (J.N.I.) and Health Sciences Research (A.B., G.D.J., E.E.C., D.J.S.); and Division of Endocrinology (S.K.), Mayo Clinic, Rochester, Minnesota 55905; Massachusetts General Hospital (P.E.G.), Harvard University, Boston, Massachusetts 02114; Rikagaku Kenkyūsho Center for Integrative Medical Science (M.K., Y.F.), Yokohama, Japan 230-0045; School of Medicine (Y.N.), Chicago University, Chicago, Illinois 60637; National Cancer Institute of Canada Clinical Trials Group (J.-A.W.C., L.E.S.), Kingston, Ontario, Canada K7L 3N6; and Division of Oncology (M.J.E.), Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110.

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http://dx.doi.org/10.1210/me.2014-1147	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179631	PMC

October 2014

Contribution of FKBP5 genetic variation to gemcitabine treatment and survival in pancreatic adenocarcinoma.

Authors:

Katarzyna A Ellsworth Bruce W Eckloff Liang Li Irene Moon Brooke L Fridley Gregory D Jenkins Erin Carlson Abra Brisbin Ryan Abo William Bamlet Gloria Petersen Eric D Wieben Liewei Wang

PLoS One 2013 1;8(8):e70216. Epub 2013 Aug 1.

Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070216	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731355	PMC

March 2014

Kernel canonical correlation analysis for assessing gene-gene interactions and application to ovarian cancer.

Authors:

Nicholas B Larson Gregory D Jenkins Melissa C Larson Robert A Vierkant Thomas A Sellers Catherine M Phelan Joellen M Schildkraut Rebecca Sutphen Paul P D Pharoah Simon A Gayther Nicolas Wentzensen Ellen L Goode Brooke L Fridley

Eur J Hum Genet 2014 Jan 17;22(1):126-31. Epub 2013 Apr 17.

1] Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA [2] Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.

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http://dx.doi.org/10.1038/ejhg.2013.69	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865403	PMC

January 2014

Integrative gene set analysis: application to platinum pharmacogenomics.

Authors:

Brooke L Fridley Ryan Abo Xiang-Lin Tan Gregory D Jenkins Anthony Batzler Ann M Moyer Joanna M Biernacka Liewei Wang

OMICS 2014 Jan 7;18(1):34-41. Epub 2013 Nov 7.

1 Department of Biostatistics, University of Kansas Medical Center , Kansas City, Kansas.

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http://dx.doi.org/10.1089/omi.2013.0099	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903166	PMC

January 2014

Soft truncation thresholding for gene set analysis of RNA-seq data: application to a vaccine study.

Authors:

Brooke L Fridley Gregory D Jenkins Diane E Grill Richard B Kennedy Gregory A Poland Ann L Oberg

Sci Rep 2013 Oct 9;3:2898. Epub 2013 Oct 9.

Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, 66160.

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http://dx.doi.org/10.1038/srep02898	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793215	PMC

October 2013

Regression modeling of allele frequencies and testing Hardy Weinberg Equilibrium.

Authors:

Daniel J Schaid Jason P Sinnwell Gregory D Jenkins

Hum Hered 2012 11;74(2):71-82. Epub 2013 Jan 11.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1159/000345846	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708318	PMC

September 2013

Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.

Authors:

James N Ingle Mohan Liu D Lawrence Wickerham Daniel J Schaid Liewei Wang Taisei Mushiroda Michiaki Kubo Joseph P Costantino Victor G Vogel Soonmyung Paik Matthew P Goetz Matthew M Ames Gregory D Jenkins Anthony Batzler Erin E Carlson David A Flockhart Norman Wolmark Yusuke Nakamura Richard M Weinshilboum

Cancer Discov 2013 Jul 13;3(7):812-25. Epub 2013 Jun 13.

Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0038	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710533	PMC

July 2013

Two-phase designs to follow-up genome-wide association signals with DNA resequencing studies.

Authors:

Daniel J Schaid Gregory D Jenkins James N Ingle Richard M Weinshilboum

Genet Epidemiol 2013 Apr 24;37(3):229-38. Epub 2013 Jan 24.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/gepi.21708	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740575	PMC

April 2013

TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.

Authors:

Mohan Liu James N Ingle Brooke L Fridley Aman U Buzdar Mark E Robson Michiaki Kubo Liewei Wang Anthony Batzler Gregory D Jenkins Tracy L Pietrzak Erin E Carlson Matthew P Goetz Donald W Northfelt Edith A Perez Clark V Williard Daniel J Schaid Yusuke Nakamura Richard M Weinshilboum

Mol Endocrinol 2013 Apr 21;27(4):657-70. Epub 2013 Mar 21.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/me.2012-1397	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607698	PMC

April 2013

Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence.

Authors:

Joanna M Biernacka Jennifer Geske Gregory D Jenkins Colin Colby David N Rider Victor M Karpyak Doo-Sup Choi Brooke L Fridley

Int J Neuropsychopharmacol 2013 Mar 2;16(2):271-8. Epub 2012 May 2.

Divisions of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1017/S1461145712000375	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854955	PMC

March 2013

FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder.

Authors:

Katarzyna A Ellsworth Irene Moon Bruce W Eckloff Brooke L Fridley Gregory D Jenkins Anthony Batzler Joanna M Biernacka Ryan Abo Abra Brisbin Yuan Ji Scott Hebbring Eric D Wieben David A Mrazek Richard M Weinshilboum Liewei Wang

Pharmacogenet Genomics 2013 Mar;23(3):156-66

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835dc133	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784025	PMC

March 2013

Identifying the genetic variation of gene expression using gene sets: application of novel gene Set eQTL approach to PharmGKB and KEGG.

Authors:

Ryan Abo Gregory D Jenkins Liewei Wang Brooke L Fridley

PLoS One 2012 14;7(8):e43301. Epub 2012 Aug 14.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043301	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419168	PMC

February 2013

Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.

Authors:

Yuan Ji Kendra K S Nordgren Yubo Chai Scott J Hebbring Gregory D Jenkins Ryan P Abo Yi Peng Linda L Pelleymounter Irene Moon Bruce W Eckloff Xiaoshan Chai Jianping Zhang Brooke L Fridley Vivien C Yee Eric D Wieben Richard M Weinshilboum

Drug Metab Dispos 2012 Oct 17;40(10):1984-92. Epub 2012 Jul 17.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.112.046953	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463826	PMC

October 2012

Localization of association signal from risk and protective variants in sequencing studies.

Authors:

Abra Brisbin Gregory D Jenkins Katarzyna A Ellsworth Liewei Wang Brooke L Fridley

Front Genet 2012 6;3:173. Epub 2012 Sep 6.

Department of Health Sciences Research, Mayo Clinic Rochester, MN, USA.

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http://dx.doi.org/10.3389/fgene.2012.00173	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434438	PMC

October 2012

Use of the gamma method for self-contained gene-set analysis of SNP data.

Authors:

Joanna M Biernacka Gregory D Jenkins Liewei Wang Ann M Moyer Brooke L Fridley

Eur J Hum Genet 2012 May 14;20(5):565-71. Epub 2011 Dec 14.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/ejhg.2011.236	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330217	PMC

May 2012

A Bayesian integrative genomic model for pathway analysis of complex traits.

Authors:

Brooke L Fridley Steven Lund Gregory D Jenkins Liewei Wang

Genet Epidemiol 2012 May 28;36(4):352-9. Epub 2012 Mar 28.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1002/gepi.21628	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894829	PMC

May 2012

Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.

Pharmacogenet Genomics 2012 Apr;22(4):247-53

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835001c9	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303952	PMC

April 2012

Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.

Authors:

Scott J Hebbring Yubo Chai Yuan Ji Ryan P Abo Gregory D Jenkins Brooke Fridley Jianping Zhang Bruce W Eckloff Eric D Wieben Richard M Weinshilboum

J Neurochem 2012 Mar 6;120(6):881-90. Epub 2012 Feb 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07646.x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296836	PMC

March 2012

Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes.

Cancer Epidemiol Biomarkers Prev 2012 Mar 2;21(3):529-36. Epub 2012 Feb 2.

Departments of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1	Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-11-0741	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297690	PMC

March 2012

Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer.

Authors:

Liang Li Daniel J Schaid Brooke L Fridley Krishna R Kalari Gregory D Jenkins Ryan P Abo Anthony Batzler Irene Moon Linda Pelleymounter Bruce W Eckloff Eric D Wieben Zhifu Sun Ping Yang Liewei Wang

Pharmacogenet Genomics 2012 Feb;22(2):105-16

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://pdfs.journals.lww.com/jpharmacogenetics/2012/02000/Ge	Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land	Publisher Site
http://dx.doi.org/10.1097/FPC.0b013e32834dd7e2	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259218	PMC

February 2012

Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies.

Authors:

Daniel J Schaid Jason P Sinnwell Gregory D Jenkins Shannon K McDonnell James N Ingle Michiaki Kubo Paul E Goss Joseph P Costantino D Lawrence Wickerham Richard M Weinshilboum

Genet Epidemiol 2012 Jan 7;36(1):3-16. Epub 2011 Dec 7.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://doi.wiley.com/10.1002/gepi.20632	Publisher Site
http://dx.doi.org/10.1002/gepi.20632	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310255	PMC

January 2012

Gene set analysis of purine and pyrimidine antimetabolites cancer therapies.

Authors:

Brooke L Fridley Anthony Batzler Liang Li Fang Li Alice Matimba Gregory D Jenkins Yuan Ji Liewei Wang Richard M Weinshilboum

Pharmacogenet Genomics 2011 Nov;21(11):701-12

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834a48a9	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192305	PMC

November 2011

A latent model for prioritization of SNPs for functional studies.

Authors:

Brooke L Fridley Ed Iversen Ya-Yu Tsai Gregory D Jenkins Ellen L Goode Thomas A Sellers

PLoS One 2011 8;6(6):e20764. Epub 2011 Jun 8.

Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020764	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110798	PMC

October 2011

Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.

Authors:

Xiang-Lin Tan Ann M Moyer Brooke L Fridley Daniel J Schaid Nifang Niu Anthony J Batzler Gregory D Jenkins Ryan P Abo Liang Li Julie M Cunningham Zhifu Sun Ping Yang Liewei Wang

Clin Cancer Res 2011 Sep 20;17(17):5801-11. Epub 2011 Jul 20.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1133	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167019	PMC

September 2011

Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen.

Authors:

Tse-Yu Wu Brooke L Fridley Gregory D Jenkins Anthony Batzler Liewei Wang Richard M Weinshilboum

Int Immunopharmacol 2011 Aug 23;11(8):1057-64. Epub 2011 Mar 23.

Division of Clinical Pharmacology, Department of Pharmacology and Experimental Therapeutics, Rochester, MN 55905, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S156757691100119	Publisher Site
http://dx.doi.org/10.1016/j.intimp.2011.02.027	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138818	PMC

August 2011

Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study.

Authors:

Ann M Moyer Brooke L Fridley Gregory D Jenkins Anthony J Batzler Linda L Pelleymounter Krishna R Kalari Yuan Ji Yubo Chai Kendra K S Nordgren Richard M Weinshilboum

Toxicol Sci 2011 Mar 22;120(1):33-41. Epub 2010 Dec 22.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://toxsci.oxfordjournals.org/content/early/2010/12/22/to	Web Search
http://www.toxsci.oxfordjournals.org/cgi/doi/10.1093/toxsci/	Publisher Site
http://dx.doi.org/10.1093/toxsci/kfq375	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044203	PMC

March 2011

Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity.

Authors:

Fang Li Brooke L Fridley Alice Matimba Krishna R Kalari Linda Pelleymounter Irene Moon Yuan Ji Gregory D Jenkins Anthony Batzler Liewei Wang Richard M Weinshilboum

Drug Metab Dispos 2010 Dec 20;38(12):2329-38. Epub 2010 Sep 20.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.110.035220	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993460	PMC

December 2010

Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.

J Clin Oncol 2010 Nov 27;28(31):4674-82. Epub 2010 Sep 27.

Mayo Clinic, Rochester, MN 55905, USA.

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http://ascopubs.org/doi/10.1200/JCO.2010.28.5064	Publisher Site
http://dx.doi.org/10.1200/JCO.2010.28.5064	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020700	PMC

November 2010

Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.

Authors:

Nifang Niu Yuxin Qin Brooke L Fridley Junmei Hou Krishna R Kalari Minjia Zhu Tse-Yu Wu Gregory D Jenkins Anthony Batzler Liewei Wang

Genome Res 2010 Nov 5;20(11):1482-92. Epub 2010 Oct 5.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1101/gr.107672.110	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963812	PMC

November 2010

Localizing putative markers in genetic association studies by incorporating linkage disequilibrium into bayesian hierarchical models.

Authors:

Brooke L Fridley Gregory D Jenkins

Hum Hered 2010 10;70(1):63-73. Epub 2010 Jun 10.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. fridley.brooke @ mayo.edu

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