Publications by authors named "Gregoire Vuagniaux"

36Publications

The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice.

PLoS One 2020 24;15(1):e0227715. Epub 2020 Jan 24.

Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.

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April 2020

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate.

PLoS One 2019 4;14(2):e0211746. Epub 2019 Feb 4.

Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.

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November 2019

SMAC Mimetic Debio 1143 and Ablative Radiation Therapy Synergize to Enhance Antitumor Immunity against Lung Cancer.

Clin Cancer Res 2019 02 23;25(3):1113-1124. Epub 2018 Oct 23.

Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.

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February 2019

HCV1b genome evolution under selective pressure of the cyclophilin inhibitor alisporivir during the DEB-025-HCV-203 phase II clinical trial.

Infect Genet Evol 2016 10 30;44:169-181. Epub 2016 Jun 30.

KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Clinical and Epidemiological Virology, Minderbroedersstraat 10, 3000 Leuven, Belgium; Center for Global Health and Tropical Medicine, Unidade de Microbiologia, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Jungquiera 100, 1349-008 Lisbon, Portugal. Electronic address:

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October 2016

A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome.

Antimicrob Agents Chemother 2016 07 20;60(7):4264-73. Epub 2016 Jun 20.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

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July 2016

A near-full length genotypic assay for HCV1b.

J Virol Methods 2014 Dec 22;209:126-35. Epub 2014 Sep 22.

Clinical and Epidemiological Virology, Rega Institute for Medical Research, Department of Microbiology and Immunology, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium.

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December 2014

Debio 0932, a new oral Hsp90 inhibitor, alleviates psoriasis in a xenograft transplantation model.

Acta Derm Venereol 2014 Nov;94(6):672-6

Department of Dermatology, Aarhus University Hospital, P. P. Oerumsgade 11, DK-8000 Aarhus, Denmark.

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November 2014

Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphisms.

Viruses 2013 Mar 22;5(3):981-97. Epub 2013 Mar 22.

Department of Immunology & Microbial Science, The Scripps Research Institute, La Jolla 92037, California, USA.

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March 2013

Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.

J Virol 2013 Feb 14;87(3):1454-64. Epub 2012 Nov 14.

Molecular Virology Laboratory, Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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February 2013

Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice.

Neuromuscul Disord 2010 Nov 15;20(11):753-60. Epub 2010 Jul 15.

Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Howard Hughes Medical Institute, 240 Albert Sabin Way, Cincinnati, OH 45229, USA.

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November 2010

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.

Nat Med 2008 Apr 16;14(4):442-7. Epub 2008 Mar 16.

Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.

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April 2008

Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice.

Am J Physiol Heart Circ Physiol 2007 Sep 8;293(3):H1654-61. Epub 2007 Jun 8.

Institut National de la Santé et de la Recherche Médicale E 0226, Université Claude Bernard Lyon I, Lyon, France.

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September 2007

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.

J Biol Chem 2007 Jan 7;282(1):58-64. Epub 2006 Nov 7.

Département de Pharmacologie et de Toxicologie, Université de Lausanne, CH-1005 Lausanne, Switzerland.

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January 2007

Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.

J Am Soc Nephrol 2006 Apr 8;17(4):968-76. Epub 2006 Mar 8.

Institut de Pharmacologie et de Toxicologie, Université de Lausanne, Rue du Bugnon 27, Lausanne, CH-1005 Switzerland.

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April 2006

In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases.

Am J Physiol Lung Cell Mol Physiol 2005 Jun 28;288(6):L1099-109. Epub 2005 Jan 28.

Department of Physiology, INSERM U426, Faculté de Medécine Xavier Bichat, Université Paris 7, Paris, France.

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June 2005

A conditional allele at the mouse channel activating protease 1 (Prss8) gene locus.

Genesis 2002 Feb;32(2):173-6

Institut de Pharmacologie et de Toxicologie de l'Université de Lausanne, Lausanne, Switzerland.

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February 2002