Publications by authors named "Greg Van Schie"

6 Publications

  • Page 1 of 1

Role of the sympathetic nervous system in cardiometabolic control: implications for targeted multiorgan neuromodulation approaches.

J Hypertens 2021 Mar 3. Epub 2021 Mar 3.

Dobney Hypertension Centre, School of Medicine - Royal Perth Hospital Unit, Faculty of Medicine, Dentistry & Health Sciences, The University of Western Australia, Perth, Western Australia Department of Radiology, Alfred Hospital Department of Surgery, Central Clinical School, Monash University, Melbourne, Victoria Medical School, The University of Western Australia, Perth, Western Australia Baker Heart and Diabetes Institute, Melbourne, Victoria Department of Endocrinology, Medical School, The University of Western Australia Department of Radiology, Royal Perth Hospital, Perth, Western Australia Human Neurotransmitter Lab Neurovascular Hypertension & Kidney Disease Laboratory, Baker Heart and Diabetes Institute, Melbourne, Victoria Departments of Cardiology and Nephrology, Royal Perth Hospital, Perth, Western Australia, Australia.

Sympathetic overdrive plays a key role in the perturbation of cardiometabolic homeostasis. Diet-induced and exercise-induced weight loss remains a key strategy to combat metabolic disorders, but is often difficult to achieve. Current pharmacological approaches result in variable responses in different patient cohorts and long-term efficacy may be limited by medication intolerance and nonadherence. A clinical need exists for complementary therapies to curb the burden of cardiometabolic diseases. One such approach may include interventional sympathetic neuromodulation of organs relevant to cardiometabolic control. The experience from catheter-based renal denervation studies clearly demonstrates the feasibility, safety and efficacy of such an approach. In analogy, denervation of the common hepatic artery is now feasible in humans and may prove to be similarly useful in modulating sympathetic overdrive directed towards the liver, pancreas and duodenum. Such a targeted multiorgan neuromodulation strategy may beneficially influence multiple aspects of the cardiometabolic disease continuum offering a holistic approach.
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http://dx.doi.org/10.1097/HJH.0000000000002839DOI Listing
March 2021

Migration of a Retained Guidewire Puncturing Multiple Organs in a Remote Australian Dialysis Patient.

J Vasc Interv Radiol 2019 Dec 1;30(12):2041-2043. Epub 2019 Nov 1.

Departments of Diagnostic and Interventional Radiology, Royal Perth Hospital, Wellington Street, Perth 6000, Western Australia; Department of Medical Imaging, Fiona Stanley Hospital, Murdoch, Western Australia.

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http://dx.doi.org/10.1016/j.jvir.2019.08.023DOI Listing
December 2019

Improved technical success and radiation safety of adrenal vein sampling using rapid, semi-quantitative point-of-care cortisol measurement.

Ann Clin Biochem 2018 Sep 22;55(5):588-592. Epub 2018 Feb 22.

1 Department of Clinical Biochemistry, PathWest Fiona Stanley Hospital Network, Murdoch, Western Australia, Australia.

Objective Primary aldosteronism is a curable cause of hypertension which can be treated surgically or medically depending on the findings of adrenal vein sampling studies. Adrenal vein sampling studies are technically demanding with a high failure rate in many centres. The use of intraprocedural cortisol measurement could improve the success rates of adrenal vein sampling but may be impracticable due to cost and effects on procedural duration. Design Retrospective review of the results of adrenal vein sampling procedures since commencement of point-of-care cortisol measurement using a novel single-use semi-quantitative measuring device for cortisol, the adrenal vein sampling Accuracy Kit.

Measurements: Success rate and complications of adrenal vein sampling procedures before and after use of the adrenal vein sampling Accuracy Kit. Routine use of the adrenal vein sampling Accuracy Kit device for intraprocedural measurement of cortisol commenced in 2016. Results Technical success rate of adrenal vein sampling increased from 63% of 99 procedures to 90% of 48 procedures ( Pā€‰=ā€‰0.0007) after implementation of the adrenal vein sampling Accuracy Kit. Failure of right adrenal vein cannulation was the main reason for an unsuccessful study. Radiation dose decreased from 34.2 Gy.cm (interquartile range, 15.8-85.9) to 15.7 Gy.cm (6.9-47.3) ( Pā€‰=ā€‰0.009). No complications were noted, and implementation costs were minimal. Conclusions Point-of-care cortisol measurement during adrenal vein sampling improved cannulation success rates and reduced radiation exposure. The use of the adrenal vein sampling Accuracy Kit is now standard practice at our centre.
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http://dx.doi.org/10.1177/0004563218760352DOI Listing
September 2018

Chronic renal vein thrombosis in a renal allograft.

Nephrology (Carlton) 2003 Oct;8(5):248-50

Renal Unit, Royal Perth Hospital, Perth, Western Australia, Australia.

Acute renal vein thrombosis in a renal allograft is uncommon and usually occurs in the post-transplant period. Chronic renal vein thrombosis can occur insidiously many years after transplant without significant deterioration in renal allograft function or symptoms.
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http://dx.doi.org/10.1046/j.1440-1797.2003.00178.xDOI Listing
October 2003

Spontaneous common iliac artery dissection after exercise.

J Endovasc Ther 2003 Feb;10(1):163-6

Department of Vascular Surgery, Royal Perth Hospital, Australia.

Purpose: To review the clinical features and management of spontaneous iliac dissections.

Case Report: A healthy 60-year-old competitive cyclist presented with acute onset of short-distance claudication following vigorous exercise. Angiography showed a dissection flap extending from the right common iliac artery to the external iliac artery. An uncovered stent was placed across the proximal entry site but did not obliterate the false lumen; open surgical intervention was required.

Conclusions: Spontaneous dissection of the iliac artery is a rare but important condition to suspect in high performance athletes complaining of leg pain following exercise.
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http://dx.doi.org/10.1177/152660280301000131DOI Listing
February 2003

Deep circumflex iliac artery as a cause of type II endoleak.

J Endovasc Ther 2003 Feb;10(1):154-7

Department of Vascular Surgery, Royal Perth Hospital, Australia.

Purpose: To report a collateral pathway involving the deep circumflex iliac artery causing a type II endoleak following endoluminal exclusion of an abdominal aortic aneurysm (AAA).

Case Report: A 75-year-old man was investigated for a persistent type II endoleak 2 years after endovascular AAA repair with a Zenith Trifab stent-graft. Angiography revealed contrast in the sac from a lumbar artery fed via a collateral of the deep circumflex iliac artery. The lumbar artery was embolized with coils, but an endoleak persisted and is being followed.

Conclusions: This collateral pathway is easily missed during angiography for endoleaks and should be considered where an endoleak is suspected but cannot be found.
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http://dx.doi.org/10.1177/152660280301000129DOI Listing
February 2003