Greg Gibson

Greg Gibson

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Greg Gibson

Greg Gibson

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Molecular Genetic and Immune Functional Responses Distinguish Bone Marrow Mesenchymal Stromal Cells from Hepatic Stellate Cells.

Stem Cells 2019 Aug 9;37(8):1075-1082. Epub 2019 May 9.

University of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1002/stem.3028DOI Listing
August 2019

TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.

Am J Hum Genet 2019 Aug 20;105(2):258-266. Epub 2019 Jun 20.

Center for Computational and Quantitative Genetics, Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.05.018DOI Listing
August 2019

Clinical utility of RNA sequencing to resolve unusual GNE myopathy with a novel promoter deletion.

Muscle Nerve 2019 Jul 29;60(1):98-103. Epub 2019 Apr 29.

Department of Human Genetics, Emory University School of Medicine, Whitehead Building Suite 301, 615 Michael Street NE, Georgia, USA.

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http://dx.doi.org/10.1002/mus.26486DOI Listing
July 2019

Classification of individuals and the potential to detect sexual contact using the microbiome of the pubic region.

Forensic Sci Int Genet 2019 07 23;41:177-187. Epub 2019 May 23.

Georgia Institute of Technology, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.fsigen.2019.05.004DOI Listing
July 2019

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.

Gastroenterology 2019 06 16;156(8):2254-2265.e3. Epub 2019 Feb 16.

Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Human Genetics, Emory University, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.01.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529254PMC
June 2019

Using Statistical Modeling to Understand and Predict Pediatric Stem Cell Function.

Circ Genom Precis Med 2019 Jun 17;12(6):e002403. Epub 2019 May 17.

The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (F.S.-T., A.G., U.A., M.O.P., M.E.D.).

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http://dx.doi.org/10.1161/CIRCGEN.118.002403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581595PMC
June 2019

Cardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Toxicol Sci 2019 May;169(1):280-292

Division of Pediatric Cardiology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.

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http://dx.doi.org/10.1093/toxsci/kfz038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484889PMC
May 2019

Bowel Location Rather Than Disease Subtype Dominates Transcriptomic Heterogeneity in Pediatric IBD.

Cell Mol Gastroenterol Hepatol 2018 1;6(4):474-476.e3. Epub 2018 Aug 1.

Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X183010
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http://dx.doi.org/10.1016/j.jcmgh.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198018PMC
April 2019

On the utilization of polygenic risk scores for therapeutic targeting.

Authors:
Greg Gibson

PLoS Genet 2019 04 25;15(4):e1008060. Epub 2019 Apr 25.

Center for Integrative Genomics and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483161PMC
April 2019

PolyQTL: Bayesian multiple eQTL detection with control for population structure and sample relatedness.

Bioinformatics 2019 Mar;35(6):1061-1063

School of Biological Sciences and Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/bty728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419993PMC
March 2019

The Effects of Age and Dose on Gene Expression and Segmental Bone Defect Repair After BMP-2 Delivery.

JBMR Plus 2019 Feb 16;3(2):e10068. Epub 2018 Jul 16.

George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology Atlanta GA USA.

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http://dx.doi.org/10.1002/jbm4.10068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383700PMC
February 2019

Going to the negative: genomics for optimized medical prescription.

Authors:
Greg Gibson

Nat Rev Genet 2019 01;20(1):1-2

Georgia Institute of Technology, School of Biological Sciences, Krone EBB, Atlanta, USA.

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http://www.nature.com/articles/s41576-018-0061-7
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http://dx.doi.org/10.1038/s41576-018-0061-7DOI Listing
January 2019

Biological relevance of computationally predicted pathogenicity of noncoding variants.

Nat Commun 2019 01 18;10(1):330. Epub 2019 Jan 18.

Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41467-018-08270-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338804PMC
January 2019

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183032
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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Individualized Transcriptional Resolution of Complicated Malaria in a Colombian Study.

J Pers Med 2018 Sep 14;8(3). Epub 2018 Sep 14.

Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.3390/jpm8030029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163772PMC
September 2018

Pervasive Modulation of Obesity Risk by the Environment and Genomic Background.

Genes (Basel) 2018 Aug 14;9(8). Epub 2018 Aug 14.

Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://www.mdpi.com/2073-4425/9/8/411
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http://dx.doi.org/10.3390/genes9080411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115725PMC
August 2018

Replicability and Prediction: Lessons and Challenges from GWAS.

Trends Genet 2018 07 30;34(7):504-517. Epub 2018 Apr 30.

CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Catalonia, Spain; Institute of Evolutionary Biology (UPF-CSIC), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain; National Institute for Bioinformatics (INB), Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), PRBB, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003860PMC
July 2018

Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease.

Genome Med 2018 06 27;10(1):48. Epub 2018 Jun 27.

Center for Integrative Genomics and School of Biological Sciences, Georgia Institute of Technology, Engineered Biosystems Building, EBB 2115, 950 Atlantic Drive, Atlanta, GA, 30332, USA.

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http://dx.doi.org/10.1186/s13073-018-0558-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020373PMC
June 2018

Population genetics and GWAS: A primer.

Authors:
Greg Gibson

PLoS Biol 2018 03 16;16(3):e2005485. Epub 2018 Mar 16.

School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.2005485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877871PMC
March 2018

Potency Analysis of Mesenchymal Stromal Cells Using a Combinatorial Assay Matrix Approach.

Cell Rep 2018 02;22(9):2504-2517

Department of Medicine, University of Wisconsin Carbone Comprehensive Cancer Center, University of Wisconsin - Madison, Madison, WI 53705, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855117PMC
February 2018

Bone Marrow-Derived Mesenchymal Stromal Cells from Patients with Sickle Cell Disease Display Intact Functionality.

Biol Blood Marrow Transplant 2017 May 26;23(5):736-745. Epub 2017 Jan 26.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791173022
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http://dx.doi.org/10.1016/j.bbmt.2017.01.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390328PMC
May 2017

The Genetic Architecture of Gene Expression in Peripheral Blood.

Am J Hum Genet 2017 02 5;100(2):228-237. Epub 2017 Jan 5.

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297163053
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http://dx.doi.org/10.1016/j.ajhg.2016.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294670PMC
February 2017

Individualization of pubic hair bacterial communities and the effects of storage time and temperature.

Forensic Sci Int Genet 2017 01 7;26:12-20. Epub 2016 Oct 7.

Georgia Institute of Technology, School of Biological Sciences, 950 Atlantic Drive, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.fsigen.2016.09.006DOI Listing
January 2017

Effects of a Health-Partner Intervention on Cardiovascular Risk.

J Am Heart Assoc 2016 10 11;5(10). Epub 2016 Oct 11.

Emory Clinical Cardiovascular Research Institute, Emory University, Atlanta, GA Center for the Study of Human Health, Emory University, Atlanta, GA Predictive Health Institute, Emory University, Atlanta, GA

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http://dx.doi.org/10.1161/JAHA.116.004217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121518PMC
October 2016

On the Evaluation of Module Preservation.

Authors:
Greg Gibson

Cell Syst 2016 07;3(1):17-9

School of Biological Sciences, Georgia Institute of Technology, Atlanta GA 30332, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.07.009DOI Listing
July 2016

Cryptic Genetic Variation in Evolutionary Developmental Genetics.

Biology (Basel) 2016 Jun 13;5(2). Epub 2016 Jun 13.

School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.3390/biology5020028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929542PMC
June 2016

Transcription Profiling of Malaria-Naïve and Semi-immune Colombian Volunteers in a Plasmodium vivax Sporozoite Challenge.

PLoS Negl Trop Dis 2015 5;9(8):e0003978. Epub 2015 Aug 5.

Caucaseco Scientific Research Center (CSRC), Cali, Colombia; School of Health, Universidad del Valle, Cali, Colombia.

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http://dx.doi.org/10.1371/journal.pntd.0003978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526565PMC
April 2016

Genomic insights into ayurvedic and western approaches to personalized medicine.

J Genet 2016 Mar;95(1):209-28

CSIR Ayurgenomics Unit-TRISUTRA, and Genomics and Molecular Medicine, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110 020,

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March 2016

A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.

Am J Hum Genet 2016 Feb;98(2):299-309

School of Biology and Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, GA 30332, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746369PMC
February 2016

PART of the WHOLE: A Case Study in Wellness-Oriented Personalized Medicine.

Yale J Biol Med 2015 Dec 24;88(4):397-406. Epub 2015 Nov 24.

School of Biology, Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, Georgia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654189PMC
December 2015

PLOS Genetics Data Sharing Policy: In Pursuit of Functional Utility.

PLoS Genet 2015 Dec 14;11(12):e1005716. Epub 2015 Dec 14.

Department of Genetics, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678900PMC
December 2015

Omic personality: implications of stable transcript and methylation profiles for personalized medicine.

Genome Med 2015 Aug 13;7:88. Epub 2015 Aug 13.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Boggs Building 1-96, 770 State Street, Atlanta, GA, 30332, USA.

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http://dx.doi.org/10.1186/s13073-015-0209-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578259PMC
August 2015

Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy.

Mol Ther 2015 Jul 22;23(7):1248-1261. Epub 2015 Apr 22.

Department of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA; Department of Pediatrics, Emory University, Atlanta, Georgia, USA. Electronic address:

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http://dx.doi.org/10.1038/mt.2015.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817795PMC
July 2015

Mature cystic fibrosis airway neutrophils suppress T cell function: evidence for a role of arginase 1 but not programmed death-ligand 1.

J Immunol 2015 Jun 29;194(11):5520-8. Epub 2015 Apr 29.

Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322; Center for Cystic Fibrosis and Airways Disease Research, Children's Healthcare of Atlanta, Atlanta, GA 30322;

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http://dx.doi.org/10.4049/jimmunol.1500312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433848PMC
June 2015

Expression quantitative trait locus analysis for translational medicine.

Genome Med 2015 24;7(1):60. Epub 2015 Jun 24.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 USA.

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http://dx.doi.org/10.1186/s13073-015-0186-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479075PMC
June 2015

Human genetics. GTEx detects genetic effects.

Authors:
Greg Gibson

Science 2015 May;348(6235):640-1

School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.1126/science.aab3002DOI Listing
May 2015

Blood gene expression profiles suggest altered immune function associated with symptoms of generalized anxiety disorder.

Brain Behav Immun 2015 Jan 7;43:184-91. Epub 2014 Oct 7.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08891591140046
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http://dx.doi.org/10.1016/j.bbi.2014.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377320PMC
January 2015

A Longitudinal Study of Health Improvement in the Atlanta CHDWB Wellness Cohort.

J Pers Med 2014 Dec 22;4(4):489-507. Epub 2014 Dec 22.

School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.3390/jpm4040489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282885PMC
December 2014

Hemani et al. reply.

Nature 2014 Oct;514(7520):E5-6

1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia [2] University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature13692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404158PMC
October 2014

Cancer: Directions for the drivers.

Authors:
Greg Gibson

Nature 2014 Aug 23;512(7512):31-2. Epub 2014 Jul 23.

School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30309, USA.

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http://dx.doi.org/10.1038/nature13649DOI Listing
August 2014

A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects.

Front Genet 2014 21;5:225. Epub 2014 Jul 21.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology Atlanta, GA, USA.

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http://dx.doi.org/10.3389/fgene.2014.00225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104702PMC
August 2014

Single cell transcriptional analysis reveals novel innate immune cell types.

PeerJ 2014 24;2:e452. Epub 2014 Jun 24.

The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.7717/peerj.452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081288PMC
July 2014

Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster.

Genetics 2014 Jun 25;197(2):781-93. Epub 2014 Mar 25.

School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332.

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http://dx.doi.org/10.1534/genetics.114.163857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063932PMC
June 2014

Gene expression profiles associated with acute myocardial infarction and risk of cardiovascular death.

Genome Med 2014 30;6(5):40. Epub 2014 May 30.

Center for Integrative Genomics and School of Biology, Georgia Institute of Technology, Boggs Building 1-96, 770 State Street, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.1186/gm560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071233PMC
June 2014

Whole genome sequencing in support of wellness and health maintenance.

Genome Med 2013 27;5(6):58. Epub 2013 Jun 27.

School of Biology, Georgia Institute of Technology, 310 Ferst Drive, Atlanta GA 30332, USA ; Center for Health Discovery and Well Being, and School of Medicine, Emory University Midtown Hospital, 550 Peachtree St, Atlanta GA 30308, USA.

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http://dx.doi.org/10.1186/gm462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967117PMC
May 2014

From personalized to public health genomics.

Genome Med 2013 19;5(7):60. Epub 2013 Jul 19.

Queensland Brain Institute and University of Queensland Diamantina Institute, Brisbane 4072, Australia.

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http://dx.doi.org/10.1186/gm464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967116PMC
May 2014

What if we had whole-genome sequence data for millions of individuals?

Genome Med 2013 20;5(9):80. Epub 2013 Sep 20.

School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm4
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http://dx.doi.org/10.1186/gm484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968547PMC
May 2014

SDS, a structural disruption score for assessment of missense variant deleteriousness.

Front Genet 2014 21;5:82. Epub 2014 Apr 21.

School of Biology, Georgia Institute of Technology Atlanta, GA, USA.

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http://dx.doi.org/10.3389/fgene.2014.00082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001065PMC
May 2014

Wellness and health omics linked to the environment: the WHOLE approach to personalized medicine.

Authors:
Greg Gibson

Adv Exp Med Biol 2014 ;799:1-14

Georgia Institute of Technology, Predictive Health Institute and School of Biology, Atlanta, GA, 30332, USA,

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http://dx.doi.org/10.1007/978-1-4614-8778-4_1DOI Listing
April 2014

Detection and replication of epistasis influencing transcription in humans.

Nature 2014 Apr 26;508(7495):249-53. Epub 2014 Feb 26.

1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia [2] University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland 4072, Australia [3].

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http://dx.doi.org/10.1038/nature13005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984375PMC
April 2014

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres.

Nucleic Acids Res 2014 Feb 22;42(4):2493-504. Epub 2013 Nov 22.

Physics Department, North Carolina State University, Raleigh, NC 27695, USA, Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219, USA, Electric and Computer Engineering Department, University of North Carolina at Charlotte, Charlotte, NC 28223, USA, Department of Industrial and System Engineering, North Carolina State University, Raleigh, NC 27695, USA, Department of Cell Biology, Center for Biologic Imaging, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219, USA, Division of Biophysics, Universität Osnabrück, Barbarstrasse 11, 49076, Osnabrück, Germany and School of Biological Sciences, University of Essex, Colchester, Essex CO4 3SQ UK.

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http://dx.doi.org/10.1093/nar/gkt1132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936710PMC
February 2014

Geographical, environmental and pathophysiological influences on the human blood transcriptome.

Curr Genet Med Rep 2013 Dec;1(4):203-211

School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.

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http://dx.doi.org/10.1007/s40142-013-0028-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377319PMC
December 2013

An association-adjusted consensus deleterious scheme to classify homozygous Mis-sense mutations for personal genome interpretation.

BioData Min 2013 Dec 23;6(1):24. Epub 2013 Dec 23.

School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.1186/1756-0381-6-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892026PMC
December 2013

Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster.

PLoS One 2013 29;8(4):e62909. Epub 2013 Apr 29.

Development and Aging Program, Neuroscience, Aging and Stem Cell Research Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062909PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639251PMC
November 2013

Genetic and nongenetic variation revealed for the principal components of human gene expression.

Genetics 2013 Nov 11;195(3):1117-28. Epub 2013 Sep 11.

University of Queensland Diamantina Institute, The Translational Research Institute, Brisbane, Queensland 4102, Australia.

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http://dx.doi.org/10.1534/genetics.113.153221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813841PMC
November 2013

Effect of normalization on statistical and biological interpretation of gene expression profiles.

Front Genet 2012 31;3:160. Epub 2013 May 31.

School of Biology, Georgia Institute of Technology Atlanta, GA, USA.

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http://dx.doi.org/10.3389/fgene.2012.00160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668151PMC
June 2013

Blood-informative transcripts define nine common axes of peripheral blood gene expression.

PLoS Genet 2013 14;9(3):e1003362. Epub 2013 Mar 14.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597511PMC
June 2013

Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data.

PLoS Genet 2013 May 16;9(5):e1003502. Epub 2013 May 16.

University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1003502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656157PMC
May 2013

Genetic risk prediction in a small cohort of healthy adults in Atlanta.

Genet Res (Camb) 2013 Feb 26;95(1):30-7. Epub 2013 Feb 26.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.1017/S0016672313000025DOI Listing
February 2013

Using blood informative transcripts in geographical genomics: impact of lifestyle on gene expression in fijians.

Front Genet 2012 9;3:243. Epub 2012 Nov 9.

Center for Integrative Genomics, School of Biology, Georgia Institute of Technology Atlanta, GA, USA ; College of Medicine, Nursing and Health Sciences, Fiji National University Suva, Fiji.

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http://dx.doi.org/10.3389/fgene.2012.00243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494018PMC
November 2012

Sexual dimorphism in multiple aspects of 3D facial symmetry and asymmetry defined by spatially dense geometric morphometrics.

J Anat 2012 Aug 18;221(2):97-114. Epub 2012 Jun 18.

K.U. Leuven, Medical Imaging Research Center (MIRC), Faculty of Engineering, Department of Electrical Engineering - ESAT, Center for Processing Speech and Images - PSI, Leuven, Belgium.

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http://dx.doi.org/10.1111/j.1469-7580.2012.01528.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406357PMC
August 2012

Circulating leukocyte telomere length is highly heritable among families of Arab descent.

BMC Med Genet 2012 May 18;13:38. Epub 2012 May 18.

Biomarkers Research Program, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-13-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458987PMC
May 2012

Rare and common variants: twenty arguments.

Authors:
Greg Gibson

Nat Rev Genet 2012 Jan 18;13(2):135-45. Epub 2012 Jan 18.

School of Biology and Center for Integrative Genomics, 770 State Street, Georgia Institute of Technology, Atlanta, Georgia 30332, USA. gatech.edu

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http://www.nature.com/articles/nrg3118
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http://dx.doi.org/10.1038/nrg3118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408201PMC
January 2012

Parent-offspring transmission of adipocytokine levels and their associations with metabolic traits.

PLoS One 2011 Apr 4;6(4):e18182. Epub 2011 Apr 4.

Biomarkers Research Program, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070726PMC
April 2011

Conference scene: biomarkers in the next decade.

Authors:
Greg Gibson

Pharmacogenomics 2011 Feb;12(2):155-7

School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://dx.doi.org/10.2217/pgs.10.210DOI Listing
February 2011

Insights from GWAS into the quantitative genetics of transcription in humans.

Genet Res (Camb) 2010 Dec;92(5-6):361-9

School of Biology, Georgia Institute of Technology, Atlanta GA 30332, USA.

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http://dx.doi.org/10.1017/S001667231000056XDOI Listing
December 2010

Sizing up the accreditation debate. Asssessing knowledge of and barriers to national paramedic program accreditation.

EMS Mag 2010 Sep;39(9):45, 47-9

National Registry of EMTs, USA.

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September 2010

Common genetic variation and performance on standardized cognitive tests.

Eur J Hum Genet 2010 Jul 3;18(7):815-20. Epub 2010 Feb 3.

Center for Human Genome Variation, Duke Institute for Genome Sciences & Policy, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1038/ejhg.2010.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987367PMC
July 2010

Genotype-by-diet interactions drive metabolic phenotype variation in Drosophila melanogaster.

Genetics 2010 Jul 12;185(3):1009-19. Epub 2010 Apr 12.

Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA.

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http://dx.doi.org/10.1534/genetics.109.113571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907188PMC
July 2010

Hints of hidden heritability in GWAS.

Authors:
Greg Gibson

Nat Genet 2010 Jul;42(7):558-60

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http://dx.doi.org/10.1038/ng0710-558DOI Listing
July 2010

Missing heritability and strategies for finding the underlying causes of complex disease.

Nat Rev Genet 2010 06;11(6):446-50

Department of Genome Sciences, University of Washington, Seattle, Washington 98195-5065, USA.

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http://dx.doi.org/10.1038/nrg2809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942068PMC
June 2010

Does size matter? Paramedic program class size may predict success.

JEMS 2009 Dec;34(12):34-5

National Registry of EMTs, USA.

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http://dx.doi.org/10.1016/S0197-2510(09)70318-3DOI Listing
December 2009