Greg Elson

Greg Elson

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Greg Elson

Greg Elson

Publications by authors named "Greg Elson"

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Tlr2 on Bone Marrow and Non-Bone Marrow Derived Cells Regulates Inflammation and Organ Injury in Cooperation with Tlr4 During Resuscitated Hemorrhagic Shock.

Shock 2016 11;46(5):519-526

*Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania †Department of Trauma Surgery, University of Heidelberg, Heidelberg, Germany ‡Novimmune SA, Geneva, Switzerland §Glenmark Pharmaceuticals SA, La-Chaux-de-Fonds, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069107PMC
http://dx.doi.org/10.1097/SHK.0000000000000650DOI Listing
November 2016

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis.

PLoS One 2015 6;10(7):e0132336. Epub 2015 Jul 6.

Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena 190, sala 203, 30130-100, Belo Horizonte, MG, Brasil; Instituto de Ciências Biologicas, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, 31270-901, Belo Horizonte, MG, Brasil.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132336PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492955PMC
April 2016

Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade.

Transplantation 2015 Jan;99(1):29-35

1 Cell Isolation and Transplantation Center, Department of Surgery, University of Geneva School of Medicine, Geneva, Switzerland. 2 Department of Endocrinology-Metabolisme and Diabetology-Nutrition, Jean Minjoz University Hospital, Besançon, France. 3 Division of Transplantation and Visceral Surgery, Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland. 4 NovImmune, Plan-les-Ouates, Switzerland.

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http://dx.doi.org/10.1097/TP.0000000000000468DOI Listing
January 2015

GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins.

Nat Biotechnol 2014 May 20;32(5):485-9. Epub 2014 Apr 20.

1] Unit for Medical Biotechnology, Inflammation Research Center (IRC), VIB, Ghent, Belgium. [2] Laboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1038/nbt.2885DOI Listing
May 2014

The composite cytokine p28/cytokine-like factor 1 sustains B cell proliferation and promotes plasma cell differentiation.

J Immunol 2013 Aug 8;191(4):1657-65. Epub 2013 Jul 8.

Département de Pharmacologie, Université de Montréal, Montréal, Québec H3T 1J4, Canada.

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http://dx.doi.org/10.4049/jimmunol.1201595DOI Listing
August 2013

IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering.

Biotechnol Bioeng 2013 Apr 23;110(4):1153-63. Epub 2012 Nov 23.

Laboratory of Molecular Biotechnology, Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/bit.24763DOI Listing
April 2013

A polyglutamic acid motif confers IL-27 hydroxyapatite and bone-binding properties.

J Immunol 2013 Mar 6;190(6):2931-7. Epub 2013 Feb 6.

Département de Pharmacologie, Université de Montréal, Montreal, Quebec H3T1J4, Canada.

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http://dx.doi.org/10.4049/jimmunol.1201460DOI Listing
March 2013

IL-6 activates STAT5 in T cells.

Cytokine 2012 Nov 31;60(2):575-82. Epub 2012 Jul 31.

Département de Pharmacologie, Université de Montréal, Montreal QC, Canada.

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http://dx.doi.org/10.1016/j.cyto.2012.07.002DOI Listing
November 2012

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis.

Am J Physiol Gastrointest Liver Physiol 2009 Jun 9;296(6):G1167-79. Epub 2009 Apr 9.

Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.

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http://www.physiology.org/doi/10.1152/ajpgi.90496.2008
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http://dx.doi.org/10.1152/ajpgi.90496.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697943PMC
June 2009

TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice.

J Exp Med 2008 Aug 21;205(8):1747-54. Epub 2008 Jul 21.

Institute of Medical Microbiology, Immunology, and Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1084/jem.20071990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525587PMC
August 2008

Increased release of sMD-2 during human endotoxemia and sepsis: a role for endothelial cells.

Mol Immunol 2008 Jun 1;45(11):3268-77. Epub 2008 Apr 1.

Department of Surgery, Nutrition and Toxicology Research Institute Maastricht, Academic Hospital Maastricht and Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900800087
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http://dx.doi.org/10.1016/j.molimm.2008.02.014DOI Listing
June 2008

Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin.

Exp Lung Res 2008 Jun;34(5):225-43

Division of Pediatric Critical Care, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1080/01902140802022492DOI Listing
June 2008

Soluble MD-2 is an acute-phase protein and an opsonin for Gram-negative bacteria.

Blood 2008 Feb 4;111(4):2122-31. Epub 2007 Dec 4.

Intensive Care, Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Switzerland.

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http://dx.doi.org/10.1182/blood-2007-06-097782DOI Listing
February 2008

Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria.

Blood 2007 Feb 12;109(4):1574-83. Epub 2006 Oct 12.

NovImmune SA, Geneva, Switzerland.

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http://dx.doi.org/10.1182/blood-2006-06-032961DOI Listing
February 2007

Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice.

Circulation 2006 Oct 16;114(18):1977-84. Epub 2006 Oct 16.

Division of Cardiology, Department of Medicine, University Hospital, Foundation for Medical Researches, 64 Avenue Roseraie, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.627430DOI Listing
October 2006

Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.

J Leukoc Biol 2006 Aug 17;80(2):227-36. Epub 2006 May 17.

Biochemisches Institut, Christian-Albrechts-Universität zu Kiel, Olshausenstr. 40, D-24098 Kiel, Germany.

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http://dx.doi.org/10.1189/jlb.1105674DOI Listing
August 2006

Detection of epsilon class switching and IgE synthesis in human B cells.

Methods Mol Biol 2006 ;315:319-29

Institut National de la Santé et de la Recherche Médicale, Unite 454, Centre Hospitalier Universitaire Arnauld de Villeneuve, Montpellier, France.

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http://dx.doi.org/10.1385/1-59259-967-2:319DOI Listing
December 2005

Gene expression of Toll-like receptor-2, Toll-like receptor-4, and MD2 is differentially regulated in rabbits with Escherichia coli pneumonia.

Gene 2005 Jan 21;344:193-202. Epub 2004 Nov 21.

Pulmonary Research Laboratories at the Seattle Department of Veterans Affairs Medical Center, University of Washington School of Medicine, 151L 1660 South Columbian Way, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1016/j.gene.2004.09.032DOI Listing
January 2005

clc is co-expressed with clf or cntfr in developing mouse muscles.

Cell Commun Signal 2005 Jan 31;3(1). Epub 2005 Jan 31.

INSERM UMR 623, Developmental Biology Institute of Marseille (CNRS – INSERM – Univ, Méditerranée), Campus de Luminy, Case 907, 13288 Marseille Cedex 09, France.

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http://dx.doi.org/10.1186/1478-811X-3-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548669PMC
January 2005

Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock.

Blood 2004 Dec 24;104(13):4071-9. Epub 2004 Aug 24.

Laboratory of the Division of Intensive Care, Department of Internal Medicine, University Hospital of Geneva, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland.

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http://dx.doi.org/10.1182/blood-2003-04-1290DOI Listing
December 2004