Grazyna Mosieniak

Grazyna Mosieniak

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Grazyna Mosieniak

Grazyna Mosieniak

Publications by authors named "Grazyna Mosieniak"

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28Publications

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Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence.

Biogerontology 2019 12 1;20(6):783-798. Epub 2019 Aug 1.

Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St, 02-093, Warsaw, Poland.

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http://dx.doi.org/10.1007/s10522-019-09825-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790191PMC
December 2019

Targeting normal and cancer senescent cells as a strategy of senotherapy.

Ageing Res Rev 2019 11 10;55:100941. Epub 2019 Aug 10.

Laboratory of Molecular Bases of Ageing, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.

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http://dx.doi.org/10.1016/j.arr.2019.100941DOI Listing
November 2019

TMA but not TMAO increases with age in rat plasma and affects smooth muscle cells viability.

J Gerontol A Biol Sci Med Sci 2019 Aug 14. Epub 2019 Aug 14.

Department of Experimental Physiology and Pathophysiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland.

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http://dx.doi.org/10.1093/gerona/glz181DOI Listing
August 2019

TMA, A Forgotten Uremic Toxin, but Not TMAO, Is Involved in Cardiovascular Pathology.

Toxins (Basel) 2019 Aug 26;11(9). Epub 2019 Aug 26.

Department of Experimental Physiology and Pathophysiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, 02-106 Warsaw, Poland.

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http://dx.doi.org/10.3390/toxins11090490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784008PMC
August 2019

The Role of Curcumin in the Modulation of Ageing.

Int J Mol Sci 2019 Mar 12;20(5). Epub 2019 Mar 12.

Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland.

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https://www.mdpi.com/1422-0067/20/5/1239
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http://dx.doi.org/10.3390/ijms20051239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429134PMC
March 2019

What is and what is not cell senescence.

Postepy Biochem 2018 Oct;64(2):110-118

Instytut Biologii Doświadczalnej PAN im. M. Nenckiego w Warszawie.

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http://dx.doi.org/10.18388/pb.2018_120DOI Listing
October 2018

Is DNA damage indispensable for stress-induced senescence?

Mech Ageing Dev 2018 03 16;170:13-21. Epub 2017 Aug 16.

Laboratory of the Molecular Bases of Ageing, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2017.08.004DOI Listing
March 2018

Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.

Cell Death Dis 2018 01 19;9(2):44. Epub 2018 Jan 19.

Laboratory of the Molecular Bases of Ageing, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.

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http://dx.doi.org/10.1038/s41419-017-0069-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833415PMC
January 2018

Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.

J Biomol Struct Dyn 2017 May 5;35(7):1474-1490. Epub 2016 Aug 5.

a Faculty of Chemistry , Warsaw University of Technology , Noakowskiego 3, 00-664 Warsaw , Poland.

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http://dx.doi.org/10.1080/07391102.2016.1186560DOI Listing
May 2017

Morphological and Functional Characteristic of Senescent Cancer Cells.

Curr Drug Targets 2016 ;17(4):377-87

Laboratory of Molecular Bases of Aging, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., Warsaw, Poland.

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http://dx.doi.org/10.2174/1389450116666151019094724DOI Listing
October 2016

NOX4 downregulation leads to senescence of human vascular smooth muscle cells.

Oncotarget 2016 Oct;7(41):66429-66443

Laboratory of Molecular Bases of Aging, Department of Biochemistry, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.

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http://dx.doi.org/10.18632/oncotarget.12079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341811PMC
October 2016

Curcumin-treated cancer cells show mitotic disturbances leading to growth arrest and induction of senescence phenotype.

Int J Biochem Cell Biol 2016 May 22;74:33-43. Epub 2016 Feb 22.

Laboratory of Molecular Bases of Aging, Nencki Institute of Experimental Biology PAS, 02-093 Warsaw, Poland.

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http://dx.doi.org/10.1016/j.biocel.2016.02.014DOI Listing
May 2016

Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence.

Neoplasia 2015 Dec;17(12):882-893

Laboratory of Molecular Bases of Aging, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, 02-093 Poland. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2015.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688565PMC
December 2015

Cellular senescence in ageing, age-related disease and longevity.

Curr Vasc Pharmacol 2014 ;12(5):698-706

Department of Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093 Warsaw, Poland.

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http://dx.doi.org/10.2174/1570161111666131219094045DOI Listing
July 2015

Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner.

Age (Dordr) 2015 Feb 4;37(1):9744. Epub 2015 Feb 4.

Department of Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteur Str. 3, 02-093, Warsaw, Poland.

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http://dx.doi.org/10.1007/s11357-014-9744-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315775PMC
February 2015

[The role of cellular senescence in carcinogenesis and antitumor therapy].

Postepy Biochem 2014 ;60(2):194-206

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September 2014

DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells.

Mutagenesis 2013 Jul 13;28(4):411-6. Epub 2013 Mar 13.

Laboratory of the Molecular Bases of Ageing, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur street, 02-093 Warsaw, Poland.

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http://dx.doi.org/10.1093/mutage/get017DOI Listing
July 2013

Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy.

Mech Ageing Dev 2012 Jun 18;133(6):444-55. Epub 2012 May 18.

Laboratory of Molecular Bases of Aging, Nencki Institute of Experimental Biology, PAS, 02-093 Warsaw, Poland.

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http://dx.doi.org/10.1016/j.mad.2012.05.004DOI Listing
June 2012

Methotrexate-induced senescence in human adenocarcinoma cells is accompanied by induction of p21(waf1/cip1) expression and lack of polyploidy.

Cancer Lett 2009 Oct 20;284(1):95-101. Epub 2009 May 20.

Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., Warsaw 02-093, Poland.

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http://dx.doi.org/10.1016/j.canlet.2009.04.015DOI Listing
October 2009

Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells.

Mech Ageing Dev 2009 Jan-Feb;130(1-2):24-32. Epub 2008 May 1.

Department of Biochemistry, Nencki Institute of Experimental Biology, Pasteura 3, 02-093 Warsaw, Poland.

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http://dx.doi.org/10.1016/j.mad.2008.04.011DOI Listing
April 2009

Curcumin induces cell death without oligonucleosomal DNA fragmentation in quiescent and proliferating human CD8+ cells.

Acta Biochim Pol 2006 2;53(3):531-8. Epub 2006 Sep 2.

Laboratory of Molecular Bases of Aging, Nencki Institute of Experimental Biology, Warszawa, Poland.

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March 2007

Curcumin abolishes apoptosis resistance of calcitriol-differentiated HL-60 cells.

FEBS Lett 2006 Aug 21;580(19):4653-60. Epub 2006 Jul 21.

Department of Cellular Biochemistry, Nencki Institute of Experimental Biology, 3 Pasteura Street, 02-093 Warsaw, Poland.

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http://dx.doi.org/10.1016/j.febslet.2006.07.038DOI Listing
August 2006

Curcumin affects components of the chromosomal passenger complex and induces mitotic catastrophe in apoptosis-resistant Bcr-Abl-expressing cells.

Mol Cancer Res 2006 Jul;4(7):457-69

Laboratory of Molecular Bases of Aging, Department of Cellular Biochemistry, Nencki Institute of Experimental Biology, Warsaw, Poland.

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http://dx.doi.org/10.1158/1541-7786.MCR-05-0172DOI Listing
July 2006