Publications by authors named "Graziella Cimino-Reale"

20Publications

Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to Enzalutamide.

J Med Chem 2018 10 20;61(19):8625-8638. Epub 2018 Sep 20.

Department of Applied Research and Technological Development , Fondazione IRCCS Istituto Nazionale dei Tumori di Milano , Via G. A. Amadeo 42 , 20133 Milan , Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00502DOI Listing
October 2018

miR-380-5p-mediated repression of TEP1 and TSPYL5 interferes with telomerase activity and favours the emergence of an "ALT-like" phenotype in diffuse malignant peritoneal mesothelioma cells.

J Hematol Oncol 2017 07 17;10(1):140. Epub 2017 Jul 17.

Molecular Pharmacology Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Amadeo, 42 - 20133, Milano, Italy.

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http://dx.doi.org/10.1186/s13045-017-0510-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513108PMC
July 2017

CPAM type 2-derived mesenchymal stem cells: Malignancy risk study in a 14-month-old boy.

Pediatr Pulmonol 2017 08 10;52(8):990-999. Epub 2017 May 10.

Pediatric Unit, Department of Internal Medicine, University of Pavia and Department of Maternal and Children's Health, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1002/ppul.23734DOI Listing
August 2017

Strategies to Strike Survival Networks in Cancer.

Crit Rev Oncog 2016 ;21(3-4):269-308

Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

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http://dx.doi.org/10.1615/CritRevOncog.2016016966DOI Listing
October 2017

Emerging Role of G-quadruplex DNA as Target in Anticancer Therapy.

Curr Pharm Des 2016 ;22(44):6612-6624

Molecular Pharmacology Unit; Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G.A. Amadeo, 42 - 20133 Milano, Italy.

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http://www.eurekaselect.com/openurl/content.php?genre=articl
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http://dx.doi.org/10.2174/1381612822666160831101031DOI Listing
March 2018

Naphthalene diimides as red fluorescent pH sensors for functional cell imaging.

Org Biomol Chem 2015 Jan;13(2):570-6

Dipartimento di Chimica, Università di Pavia, V.le Taramelli 10, 27100 Pavia, Italy.

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http://xlink.rsc.org/?DOI=C4OB02054E
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http://dx.doi.org/10.1039/c4ob02054eDOI Listing
January 2015

Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells.

Int J Oncol 2015 Jan 23;46(1):369-80. Epub 2014 Oct 23.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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http://dx.doi.org/10.3892/ijo.2014.2723DOI Listing
January 2015

MicroRNA-dependent regulation of telomere maintenance mechanisms: a field as much unexplored as potentially promising.

Curr Pharm Des 2014 ;20(41):6404-21

Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Amadeo, 42 - 20133 Milano, Italy.

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http://dx.doi.org/10.2174/1381612820666140630095918DOI Listing
June 2015

G-quadruplex structures in the human genome as novel therapeutic targets.

Molecules 2013 Oct 8;18(10):12368-95. Epub 2013 Oct 8.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Amadeo 42, Milano 20133, Italy.

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http://dx.doi.org/10.3390/molecules181012368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270421PMC
October 2013

Tel1 and Rad51 are involved in the maintenance of telomeres with capping deficiency.

Nucleic Acids Res 2013 Jul 15;41(13):6490-500. Epub 2013 May 15.

Dipartimento di Biologia e Biotecnologie 'Charles Darwin', Sapienza Università di Roma, 00185 Rome, Italy.

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http://dx.doi.org/10.1093/nar/gkt365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711455PMC
July 2013

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage.

Autophagy 2012 Aug 25;8(8):1185-96. Epub 2012 May 25.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.4161/auto.20519DOI Listing
August 2012

Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance.

Neuro Oncol 2012 Jun 19;14(6):736-44. Epub 2012 Apr 19.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.1093/neuonc/nos083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367852PMC
June 2012

Telomeres as targets for anticancer therapies.

Expert Opin Ther Targets 2011 May 3;15(5):579-93. Epub 2011 Feb 3.

Fondazione IRCCS Istituto Nazionale Tumori, Department of Experimental Oncology and Molecular Medicine, Milan, Italy.

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http://dx.doi.org/10.1517/14728222.2011.556621DOI Listing
May 2011

Combined in utero and juvenile exposure of mice to arsenate and atrazine in drinking water modulates gene expression and clonogenicity of myeloid progenitors.

Toxicol Lett 2008 Jul 8;180(1):59-66. Epub 2008 Jun 8.

Joint Research Centre, Physical and Chemical Exposure Unit (PCE), Institute for the Health and Consumer Protection, via E. Fermi 1, 21020 Ispra (VA), Italy.

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http://dx.doi.org/10.1016/j.toxlet.2008.06.005DOI Listing
July 2008

Tumor cells fail to trans-induce telomerase in human umbilical vein endothelial cell cultures.

Cancer Res 2004 Nov;64(21):7702-5

Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, Roma, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1711DOI Listing
November 2004

Chordoma of the skull base: predictors of tumor recurrence.

J Neurosurg 2003 Apr;98(4):812-22

Institute of Neurosurgery, Departmnet of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.3171/jns.2003.98.4.0812DOI Listing
April 2003

Long telomeric C-rich 5'-tails in human replicating cells.

J Biol Chem 2003 Jan 14;278(4):2136-40. Epub 2002 Nov 14.

Istituto di Neurobiologia e Medicina Molecolare, Consiglio Nazionale delle Ricerche, 00137 Roma, Italy.

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http://dx.doi.org/10.1074/jbc.M208939200DOI Listing
January 2003