Grazia Lombardi

Grazia Lombardi

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Grazia Lombardi

Grazia Lombardi

Publications by authors named "Grazia Lombardi"

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Exploring calixarene-based clusters for efficient functional presentation of Streptococcus pneumoniae saccharides.

Bioorg Chem 2019 Dec 19;93:103305. Epub 2019 Sep 19.

Department of Medical Biotechnology and Translational Medicine, University of Milan, Via Saldini 50, 20133 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103305DOI Listing
December 2019

Anomeric sugar boronic acid analogues as potential agents for boron neutron capture therapy.

Beilstein J Org Chem 2019 19;15:1355-1359. Epub 2019 Jun 19.

Department of Pharmaceutical Sciences, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.

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http://dx.doi.org/10.3762/bjoc.15.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604725PMC
June 2019

Synthesis and biological evaluation of a trisaccharide repeating unit derivative of Streptococcus pneumoniae 19A capsular polysaccharide.

Bioorg Med Chem 2018 11 19;26(21):5682-5690. Epub 2018 Oct 19.

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Via Saldini 50, 20133 Milano, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183129
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http://dx.doi.org/10.1016/j.bmc.2018.10.016DOI Listing
November 2018

"In vitro" studies on galectin-3 in human natural killer cells.

Immunol Lett 2018 02 14;194:4-12. Epub 2017 Dec 14.

Department of Pharmaceutical Sciences, University of "Piemonte Orientale, A. Avogadro", Largo Donegani 2, 28100 Novara, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01652478173036
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http://dx.doi.org/10.1016/j.imlet.2017.12.004DOI Listing
February 2018

Immunological characterization of a rigid α-Tn mimetic on murine iNKT and human NK cells.

Glycoconj J 2017 08 1;34(4):553-562. Epub 2017 Jun 1.

Department of Chemistry "Ugo Schiff", University of Florence, Via della Lastruccia 13, 50019, Sesto Fiorentino, FI, Italy.

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http://dx.doi.org/10.1007/s10719-017-9775-6DOI Listing
August 2017

Synthesis of Sugar-Boronic Acid Derivatives: A Class of Potential Agents for Boron Neutron Capture Therapy.

Org Lett 2017 04 28;19(7):1678-1681. Epub 2017 Mar 28.

Department of Pharmaceutical Sciences, Università del Piemonte Orientale , Largo Donegani 2, 28100 Novara, Italy.

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http://dx.doi.org/10.1021/acs.orglett.7b00382DOI Listing
April 2017

Synthesis of di- and tri-saccharide fragments of Salmonella typhi Vi capsular polysaccharide and their zwitterionic analogues.

Bioorg Med Chem 2015 Dec 30;23(23):7439-47. Epub 2015 Oct 30.

Department of Chemistry and CRC Materiali Polimerici (LaMPo), University of Milan, Via Golgi 19, 20133 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.10.043DOI Listing
December 2015

Iron oxide superparamagnetic nanoparticles conjugated with a conformationally blocked α-Tn antigen mimetic for macrophage activation.

Nanoscale 2014 Jul;6(13):7643-55

Dipartimento di Chimica "U. Schiff" and INSTM, Università di Firenze, via della Lastruccia 3, Sesto Fiorentino, I-50019 Firenze, Italy.

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http://dx.doi.org/10.1039/c4nr00070fDOI Listing
July 2014

Factors affecting T cell responses induced by fully synthetic glyco-gold-nanoparticles.

Nanoscale 2013 Jan 23;5(1):390-400. Epub 2012 Nov 23.

Department of Pharmaceutical Sciences, University of Piemonte Orientale Amedeo Avogadro, Via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1039/c2nr32338aDOI Listing
January 2013

Increased frequency of circulating invariant natural killer T cells in malignant pleural mesothelioma patients.

Cancer Biol Ther 2012 Jul 11;13(9):702-11. Epub 2012 Jun 11.

Department of Pharmaceutical Sciences, University of "Piemonte Orientale Amedeo Avogadro", Novara, Italy.

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http://dx.doi.org/10.4161/cbt.20553DOI Listing
July 2012

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

Authors:
Christopher A Maxwell Javier Benítez Laia Gómez-Baldó Ana Osorio Núria Bonifaci Ricardo Fernández-Ramires Sylvain V Costes Elisabet Guinó Helen Chen Gareth J R Evans Pooja Mohan Isabel Català Anna Petit Helena Aguilar Alberto Villanueva Alvaro Aytes Jordi Serra-Musach Gad Rennert Flavio Lejbkowicz Paolo Peterlongo Siranoush Manoukian Bernard Peissel Carla B Ripamonti Bernardo Bonanni Alessandra Viel Anna Allavena Loris Bernard Paolo Radice Eitan Friedman Bella Kaufman Yael Laitman Maya Dubrovsky Roni Milgrom Anna Jakubowska Cezary Cybulski Bohdan Gorski Katarzyna Jaworska Katarzyna Durda Grzegorz Sukiennicki Jan Lubiński Yin Yao Shugart Susan M Domchek Richard Letrero Barbara L Weber Frans B L Hogervorst Matti A Rookus J Margriet Collee Peter Devilee Marjolijn J Ligtenberg Rob B van der Luijt Cora M Aalfs Quinten Waisfisz Juul Wijnen Cornelis E P van Roozendaal Douglas F Easton Susan Peock Margaret Cook Clare Oliver Debra Frost Patricia Harrington D Gareth Evans Fiona Lalloo Rosalind Eeles Louise Izatt Carol Chu Diana Eccles Fiona Douglas Carole Brewer Heli Nevanlinna Tuomas Heikkinen Fergus J Couch Noralane M Lindor Xianshu Wang Andrew K Godwin Maria A Caligo Grazia Lombardi Niklas Loman Per Karlsson Hans Ehrencrona Anna von Wachenfeldt Rosa Bjork Barkardottir Ute Hamann Muhammad U Rashid Adriana Lasa Trinidad Caldés Raquel Andrés Michael Schmitt Volker Assmann Kristen Stevens Kenneth Offit João Curado Hagen Tilgner Roderic Guigó Gemma Aiza Joan Brunet Joan Castellsagué Griselda Martrat Ander Urruticoechea Ignacio Blanco Laima Tihomirova David E Goldgar Saundra Buys Esther M John Alexander Miron Melissa Southey Mary B Daly Rita K Schmutzler Barbara Wappenschmidt Alfons Meindl Norbert Arnold Helmut Deissler Raymonda Varon-Mateeva Christian Sutter Dieter Niederacher Evgeny Imyamitov Olga M Sinilnikova Dominique Stoppa-Lyonne Sylvie Mazoyer Carole Verny-Pierre Laurent Castera Antoine de Pauw Yves-Jean Bignon Nancy Uhrhammer Jean-Philippe Peyrat Philippe Vennin Sandra Fert Ferrer Marie-Agnès Collonge-Rame Isabelle Mortemousque Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Sue Healey Mary Helen Barcellos-Hoff Marc Vidal Stephen B Gruber Conxi Lázaro Gabriel Capellá Lesley McGuffog Katherine L Nathanson Antonis C Antoniou Georgia Chenevix-Trench Markus C Fleisch Víctor Moreno Miguel Angel Pujana

PLoS Biol 2011 Nov 15;9(11):e1001199. Epub 2011 Nov 15.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute-IDIBELL, L'Hospitalet, Catalonia, Spain.

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http://dx.doi.org/10.1371/journal.pbio.1001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217025PMC
November 2011

Synthetic isoforms of endogenous sulfatides differently modulate indoleamine 2,3-dioxygenase in antigen presenting cells.

Life Sci 2011 Aug 13;89(5-6):176-81. Epub 2011 Jun 13.

DISCAFF, University of “Piemonte Orientale Amedeo Avogadro”, Via Giovanni Bovio, Novara, Italy.

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http://dx.doi.org/10.1016/j.lfs.2011.05.015DOI Listing
August 2011

A recombination-based method to characterize human BRCA1 missense variants.

Breast Cancer Res Treat 2011 Jan 25;125(1):265-72. Epub 2010 Aug 25.

Section of Genetic Oncology, University Hospital and University of Pisa, Pisa, Italy.

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http://link.springer.com/content/pdf/10.1007/s10549-010-1112
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http://link.springer.com/10.1007/s10549-010-1112-8
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http://dx.doi.org/10.1007/s10549-010-1112-8DOI Listing
January 2011

Do CYP3A and ABCB1 genotypes influence the plasma concentration and clinical outcome of donepezil treatment?

Eur J Clin Pharmacol 2011 Jan 8;67(1):47-54. Epub 2010 Oct 8.

DISCAFF Department, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.

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http://dx.doi.org/10.1007/s00228-010-0883-5DOI Listing
January 2011

PALB2: a novel inactivating mutation in a Italian breast cancer family.

Fam Cancer 2010 Dec;9(4):531-6

Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and Santa Chiara University Hospital, Pisa, Italy.

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http://dx.doi.org/10.1007/s10689-010-9382-1DOI Listing
December 2010

Expression of functional GPR35 in human iNKT cells.

Biochem Biophys Res Commun 2010 Jul 25;398(3):420-5. Epub 2010 Jun 25.

Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche (DISCAFF), University of Piemonte Orientale Amedeo Avogadro, Via Giovanni Bovio, 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2010.06.091DOI Listing
July 2010

PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss.

Neurochem Int 2009 Dec 13;55(7):496-504. Epub 2009 May 13.

Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, Italy.

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http://dx.doi.org/10.1016/j.neuint.2009.05.001DOI Listing
December 2009

Anti-inflammatory and vascularprotective properties of 8-prenylapigenin.

Eur J Pharmacol 2009 Oct 15;620(1-3):120-30. Epub 2009 Aug 15.

DISCAFF Department, University of Piemonte Orientale Amedeo Avogadro, Novara, Italy.

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http://dx.doi.org/10.1016/j.ejphar.2009.08.015DOI Listing
October 2009

Characterisation of gene expression profiles of yeast cells expressing BRCA1 missense variants.

Eur J Cancer 2009 Aug 1;45(12):2187-96. Epub 2009 Jun 1.

Department of Experimental Pathology, Medical Biotechnology, Epidemiology and Infectious Diseases, University of Pisa, via Roma 55, 56126 Pisa, Italy.

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http://dx.doi.org/10.1016/j.ejca.2009.04.025DOI Listing
August 2009

Synthesis of alpha-galactosyl ceramide (KRN7000) and analogues thereof via a common precursor and their preliminary biological assessment.

J Org Chem 2008 Nov 29;73(22):9192-5. Epub 2008 Oct 29.

Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Università del Piemonte Orientale Amedeo Avogadro, via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1021/jo8019994DOI Listing
November 2008

Alpha-galactosylceramide modulates the induction of indoleamine 2,3-dioxygenase in antigen presenting cells.

Biochem Pharmacol 2008 Sep 11;76(6):738-50. Epub 2008 Jul 11.

DISCAFF Department, University of Piemonte Orientale, Via Bovio, 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/j.bcp.2008.07.001DOI Listing
September 2008

Identification of novel alternatively spliced BRCA1-associated RING domain (BARD1) messenger RNAs in human peripheral blood lymphocytes and in sporadic breast cancer tissues.

Genes Chromosomes Cancer 2007 Sep;46(9):791-5

Division of Surgical, Molecular and Ultrastructural Pathology, Department of Oncology, University of Pisa and Pisa University Hospital, Via Roma 57, 56126 Pisa, Italy.

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http://dx.doi.org/10.1002/gcc.20460DOI Listing
September 2007

Synthesis and biological evaluation of phosphono analogues of capsular polysaccharide fragments from Neisseria meningitidis A.

Chemistry 2007 ;13(23):6623-35

Dipartimento di Chimica Organica e Industriale and Centro Interdisciplinare Studi Bio-molecolari e Applicazioni Industriali, Università degli Studi di Milano via Venezian 21, 20133 Milano, Italy.

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http://dx.doi.org/10.1002/chem.200601743DOI Listing
September 2007

Stimulation of N-methyl-D-aspartate receptors modulates Jurkat T cell growth and adhesion to fibronectin.

Biochem Biophys Res Commun 2007 Sep 20;361(2):404-9. Epub 2007 Jul 20.

Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, Via Pietro Giuria 9, 10125 Turin, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2007.07.015DOI Listing
September 2007

A general and stereoselective route to alpha- or beta-galactosphingolipids via a common four-carbon building block.

J Org Chem 2007 Sep 5;72(20):7757-60. Epub 2007 Sep 5.

Dipartimento di Chimica, Biochimica e Biotecnologie per la Medicina, Università di Milano, Via Saldini 50, 20133-Milano, Italy.

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http://pubs.acs.org/doi/abs/10.1021/jo070849z
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http://dx.doi.org/10.1021/jo070849zDOI Listing
September 2007

High level of messenger RNA for BRMS1 in primary breast carcinomas is associated with poor prognosis.

Int J Cancer 2007 Mar;120(6):1169-78

Division of Surgical, Molecular and Ultrastructural Pathology, Department of Oncology, University of Pisa and Pisa University Hospital, Via Roma 57, 56126 Pisa, Italy.

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http://dx.doi.org/10.1002/ijc.22379DOI Listing
March 2007

Oxyhomologation of the amide bond potentiates neuroprotective effects of the endolipid N-palmitoylethanolamine.

J Pharmacol Exp Ther 2007 Feb 26;320(2):599-606. Epub 2006 Oct 26.

Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche, e Farmacologiche, University of Piemonte Orientale Amedeo Avogadro, Via Bovio, 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1124/jpet.106.112987DOI Listing
February 2007

RNA-based analysis of BRCA1 and BRCA2 gene alterations.

Cancer Genet Cytogenet 2006 Oct;170(2):93-101

Section of Genetic Oncology, Division of Surgical, Molecular and Ultrastructural Pathology, University of Pisa and Pisa University Hospital, Via Roma, Pisa, Italy.

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http://dx.doi.org/10.1016/j.cancergencyto.2006.05.005DOI Listing
October 2006

Impact of the CYP2D6 polymorphism on steady-state plasma concentrations and clinical outcome of donepezil in Alzheimer's disease patients.

Eur J Clin Pharmacol 2006 Sep 15;62(9):721-6. Epub 2006 Jul 15.

DISCAFF Department, Amedeo Avogadro University of Eastern Piedmont, Via Bovio, 6, 28100 Novara, Italy.

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http://www.springerlink.com/index/l16n7676308x71u2.pdf
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http://dx.doi.org/10.1007/s00228-006-0168-1DOI Listing
September 2006

Cholesteryl butyrate solid lipid nanoparticles inhibit adhesion of human neutrophils to endothelial cells.

Br J Pharmacol 2006 Jul 15;148(5):648-56. Epub 2006 May 15.

Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, Torino 10125, Italy.

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http://dx.doi.org/10.1038/sj.bjp.0706761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751876PMC
July 2006

Group I mGlu receptor stimulation inhibits activation-induced cell death of human T lymphocytes.

Br J Pharmacol 2006 Jul 5;148(6):760-8. Epub 2006 Jun 5.

Interdisciplinary Research Center of Autoimmune Diseases, Department of Medical Sciences, Eastern Piedmont University, Via Solaroli, 17, 28100 Novara, Italy.

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http://dx.doi.org/10.1038/sj.bjp.0706746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617076PMC
July 2006

Human T lymphocytes express N-methyl-D-aspartate receptors functionally active in controlling T cell activation.

Biochem Biophys Res Commun 2005 Dec 9;338(4):1875-83. Epub 2005 Nov 9.

DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2005.10.164DOI Listing
December 2005

Stimulation of group I metabotropic glutamate receptors evokes calcium signals and c-jun and c-fos gene expression in human T cells.

Biochem Pharmacol 2005 Jul;70(2):189-99

DISCAFF, "Amedeo Avogadro" University of Eastern Piedmont, Via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/j.bcp.2005.04.038DOI Listing
July 2005

Haplotype analysis of BRCA1 gene reveals a new gene rearrangement: characterization of a 19.9 KBP deletion.

Eur J Hum Genet 2004 Sep;12(9):775-7

Section of Oncogenetics, Division of Surgical, Molecular and Ultrastructural Pathology, Department of Oncology, Transplants and New Technologies in Medicine, University of Pisa and University Hospital of Pisa, Italy.

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http://dx.doi.org/10.1038/sj.ejhg.5201223DOI Listing
September 2004

Glutamate modulation of human lymphocyte growth: in vitro studies.

Biochem Biophys Res Commun 2004 May;318(2):496-502

Interdisciplinary Research Center of Autoimmune Diseases, DISCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.053DOI Listing
May 2004

Cabergoline protects SH-SY5Y neuronal cells in an in vitro model of ischemia.

Eur J Pharmacol 2004 Apr;489(3):157-65

DISCAFF Department, University of Piemonte Orientale Amedeo Avogadro, Via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/j.ejphar.2004.03.006DOI Listing
April 2004

Involvement of beta(1) integrin in betaAP-induced apoptosis in human neuroblastoma cells.

Mol Cell Neurosci 2004 Jan;25(1):1-8

Department of Medical Science, University of Piemonte Orientale "A. Avogadro", Novara, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S104474310300290
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http://dx.doi.org/10.1016/j.mcn.2003.09.008DOI Listing
January 2004

Targeting of A701G nucleotide at the human ATP1A1 locus using a RNA/DNA chimera.

Nucleosides Nucleotides Nucleic Acids 2002 Nov-Dec;21(11-12):775-84

Laboratorio di Terapia Genica e Molecolare, Istituto di Fisiologia Clinica, Area della Ricerca del CNR, via G. Moruzzi, 1, 56127 Pisa, Italy.

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http://www.tandfonline.com/doi/abs/10.1081/NCN-120016480
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http://dx.doi.org/10.1081/NCN-120016480DOI Listing
September 2003

Substance P increases neutrophil adhesion to human umbilical vein endothelial cells.

Br J Pharmacol 2003 Jul;139(6):1103-10

Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, 10125 Torino, Italy.

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http://dx.doi.org/10.1038/sj.bjp.0705344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573938PMC
July 2003

Abnormal response to glutamate of T lymphocytes from multiple sclerosis patients.

Neurosci Lett 2003 Apr;340(1):5-8

DISCAFF Department, University of Piemonte Orientale "Amedeo Avogadro", Via Bovio, 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/s0304-3940(03)00038-7DOI Listing
April 2003

Cabergoline prevents necrotic neuronal death in an in vitro model of oxidative stress.

Eur J Pharmacol 2002 Dec;457(2-3):95-8

DISCAFF Department, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.

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http://dx.doi.org/10.1016/s0014-2999(02)02683-3DOI Listing
December 2002