Publications by authors named "Grazia Graziani"

97Publications

Targeting Tumor-Associated Macrophages to Increase the Efficacy of Immune Checkpoint Inhibitors: A Glimpse into Novel Therapeutic Approaches for Metastatic Melanoma.

Cancers (Basel) 2020 Nov 17;12(11). Epub 2020 Nov 17.

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/cancers12113401DOI Listing
November 2020

PDIA3 Expression in Glioblastoma Modulates Macrophage/Microglia Pro-Tumor Activation.

Int J Mol Sci 2020 Nov 3;21(21). Epub 2020 Nov 3.

Dipartimento di Bioetica e Sicurezza, Sezione di Farmacologia-Catholic University Medical School, 00168 Rome, Italy.

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http://dx.doi.org/10.3390/ijms21218214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662700PMC
November 2020

Approaching coronavirus disease 2019: Mechanisms of action of repurposed drugs with potential activity against SARS-CoV-2.

Biochem Pharmacol 2020 10 23;180:114169. Epub 2020 Jul 23.

Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2020.114169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375972PMC
October 2020

Strategies to improve ellagic acid bioavailability: from natural or semisynthetic derivatives to nanotechnological approaches based on innovative carriers.

Nanotechnology 2020 Sep 7;31(38):382001. Epub 2020 May 7.

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1 00133, Rome, Italy.

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http://dx.doi.org/10.1088/1361-6528/ab912cDOI Listing
September 2020

Vascular endothelial growth factor receptor 1 in glioblastoma‑associated microglia/macrophages.

Oncol Rep 2020 Jun 19;43(6):2083-2092. Epub 2020 Mar 19.

Institute of Pharmacology, Catholic University Medical School, I‑00168 Rome, Italy.

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http://dx.doi.org/10.3892/or.2020.7553DOI Listing
June 2020

Role of VEGFs/VEGFR-1 Signaling and its Inhibition in Modulating Tumor Invasion: Experimental Evidence in Different Metastatic Cancer Models.

Int J Mol Sci 2020 Feb 18;21(4). Epub 2020 Feb 18.

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms21041388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073125PMC
February 2020

DNA inhibitors for the treatment of brain tumors.

Expert Opin Drug Metab Toxicol 2020 Mar 26;16(3):195-207. Epub 2020 Feb 26.

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1080/17425255.2020.1729352DOI Listing
March 2020

Effects of Glutathione Transferase-Targeting Nitrobenzoxadiazole Compounds in Relation to PD-L1 Status in Human Melanoma Cells.

Chemotherapy 2019 22;64(3):138-145. Epub 2019 Oct 22.

Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy,

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http://dx.doi.org/10.1159/000503339DOI Listing
December 2019

On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment.

Chemotherapy 2019 6;64(2):62-80. Epub 2019 Aug 6.

Laboratory of Molecular Oncology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, Rome, Italy.

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http://dx.doi.org/10.1159/000500902DOI Listing
November 2019

Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders.

Biochem Pharmacol 2019 09 24;167:133-148. Epub 2019 Apr 24.

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.04.019DOI Listing
September 2019

Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors.

Cancers (Basel) 2018 Dec 4;10(12). Epub 2018 Dec 4.

Department of Systems Medicine, University of Rome Tor Vergata, 00173 Rom, Italy.

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http://www.mdpi.com/2072-6694/10/12/487
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http://dx.doi.org/10.3390/cancers10120487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316750PMC
December 2018

Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid.

Nutrients 2018 Nov 14;10(11). Epub 2018 Nov 14.

Department of Systems Medicine, University of Rome Tor Vergata, 00173 Rome, Italy.

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http://dx.doi.org/10.3390/nu10111756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266224PMC
November 2018

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors.

Pharmacol Res 2018 10 28;136:97-107. Epub 2018 Aug 28.

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2018.08.023DOI Listing
October 2018

Poly(ADP-ribose) polymerase inhibitor olaparib hampers placental growth factor-driven activation of myelomonocytic cells.

Oncol Rep 2018 May 5;39(5):2261-2269. Epub 2018 Mar 5.

Department of Systems Medicine, University of Rome 'Tor Vergata', I‑00133 Rome, Italy.

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http://dx.doi.org/10.3892/or.2018.6291DOI Listing
May 2018

The Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody D16F7 Inhibits Glioma Growth and Angiogenesis In Vivo.

J Pharmacol Exp Ther 2018 01 12;364(1):77-86. Epub 2017 Oct 12.

Departments of Systems Medicine (M.G.A., L.T., C.C., G.G.) and Experimental Medicine and Surgery (E.B., M.S.), University of Rome Tor Vergata, Rome, Italy; and Laboratory of Molecular Oncology, "Istituto Dermopatico dell'Immacolata"-Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (F.R., P.M.L.)

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http://dx.doi.org/10.1124/jpet.117.244434DOI Listing
January 2018

Platelet-derived growth factor-C promotes human melanoma aggressiveness through activation of neuropilin-1.

Oncotarget 2017 Sep 27;8(40):66833-66848. Epub 2017 Jun 27.

Laboratory of Molecular Oncology, "Istituto Dermopatico dell'Immacolata"-IRCCS, Rome, Italy.

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http://www.oncotarget.com/fulltext/18706
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http://dx.doi.org/10.18632/oncotarget.18706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620139PMC
September 2017

Modulation of GDF11 expression and synaptic plasticity by age and training.

Oncotarget 2017 Aug 3;8(35):57991-58002. Epub 2017 Aug 3.

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.19854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601628PMC
August 2017

Exploiting Microglial Functions for the Treatment of Glioblastoma.

Curr Cancer Drug Targets 2017 ;17(3):267-281

Institute of Pharmacology, Catholic University Medical School, Rome, Italy.

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http://dx.doi.org/10.2174/1568009616666160813191240DOI Listing
October 2017

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Neuro Oncol 2016 12 10;18(12):1644-1655. Epub 2016 Jun 10.

Department of Biomedicine, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., T.T., K.V., J.A.H., J.V.J., R.J., H.S.S., L.L., T.D., P.Ø.E., R.B., H.M.); KG Jebsen Brain Tumor Research Center, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., K.V., J.A.H., J.V.J., T.D., P. Ø.E., S.P.N., R.B., H.M.); Department of Clinical Science, University of Bergen, Norway (S.K.); Department of Oncology, Haukeland University Hospital, Bergen, Norway (S.K.); Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (O.K., S.F., S.P.N., R.B.); Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK (A.S.); Department of Clinical Pharmacy, Institute of Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany (S.F., C.A.R.); Department of Neurooncology, University Hospital Heidelberg, Germany (G.S., F.W.); Institute of Scientific Instruments, ASCR, Brno, Czech Republic (R.J.); Edinger-Intsitute, Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H.); Department of Pathology, Haukeland University Hospital, Bergen, Norway (J.A.H., H.M.); Department of Clinical Neurosciences, University of Cambridge, UK (S.G.P., C.W.); Statistics and Computational Biology Laboratory, University of Cambridge, UK (I.S.); Neuro Clinic, Haukeland University Hospital, Bergen, Norway; Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, Germany (P.E.); Department of Systems Medicine, University of Rome «Tor Vergata», Rome, Italy (G.G.); INSERM U1029 - University of Bordeaux, Allée Geoffroy St. Hilaire, Pessac, France (T.D.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (M.L.-J., P. Ø.E.).

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http://dx.doi.org/10.1093/neuonc/now113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791772PMC
December 2016

Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.

Int J Oncol 2016 Apr 29;48(4):1581-9. Epub 2016 Jan 29.

Laboratory of Molecular Oncology, 'Istituto Dermopatico dell'Immacolata'- IRCCS, Rome, Italy.

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http://dx.doi.org/10.3892/ijo.2016.3362DOI Listing
April 2016

Editorial.

Chemotherapy 2016 3;61(1):1-2. Epub 2015 Nov 3.

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http://dx.doi.org/10.1159/000441664DOI Listing
August 2016

Neuropilin-1 as Therapeutic Target for Malignant Melanoma.

Front Oncol 2015 3;5:125. Epub 2015 Jun 3.

Laboratory of Molecular Oncology, "Istituto Dermopatico dell'Immacolata", Istituto di Ricovero e Cura a Carattere Scientifico , Rome , Italy.

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http://dx.doi.org/10.3389/fonc.2015.00125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453476PMC
June 2015

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib.

Biochem Pharmacol 2015 May 17;95(1):16-27. Epub 2015 Mar 17.

The NAST Centre for Nanoscience & Nanotechnology & Innovative Instrumentation, University of "Tor Vergata", Rome, Italy; Department of Experimental Medicine and Surgery, University of "Tor Vergata", Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.03.004DOI Listing
May 2015

BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib.

Biochim Biophys Acta 2015 Mar 5;1852(3):462-72. Epub 2014 Dec 5.

Unit of Neuro-Oncohematology, Santa Lucia Foundation-I.R.C.C.S., Rome, Italy; Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.12.001DOI Listing
March 2015

Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.

Int J Cancer 2015 Mar 28;136(6):E545-58. Epub 2014 Nov 28.

Laboratory of Molecular Oncology, "Istituto Dermopatico dell'Immacolata"-IRCCS, Rome, Italy.

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http://dx.doi.org/10.1002/ijc.29252DOI Listing
March 2015

PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets.

Front Oncol 2013 14;3:279. Epub 2013 Nov 14.

Laboratory for Skin Cancer Research, CHU-Q (CHUL) Research Centre, Laval University , Quebec City, QC , Canada.

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http://dx.doi.org/10.3389/fonc.2013.00279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827545PMC
December 2013

Challenging resistance mechanisms to therapies for metastatic melanoma.

Trends Pharmacol Sci 2013 Dec 7;34(12):656-66. Epub 2013 Nov 7.

Department of System Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.tips.2013.10.003DOI Listing
December 2013

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.

Oncol Rep 2013 Dec 10;30(6):2887-96. Epub 2013 Oct 10.

Laboratory of Molecular Oncology, 'Istituto Dermopatico dell'Immacolata'- IRCCS, Rome, Italy.

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http://dx.doi.org/10.3892/or.2013.2791DOI Listing
December 2013

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion.

J Pharmacol Exp Ther 2013 Oct 26;347(1):164-72. Epub 2013 Jul 26.

Laboratory of Molecular Oncology, "Istituto Dermopatico dell'Immacolata-IRCCS," Rome, Italy (P.M.L., F.R.); Department of Medicine, University of Perugia, Perugia, Italy (M.G.P., R.B., S.R., G.M., C.R., G.N.); and Department of System Medicine, University of Rome "Tor Vergata," Rome, Italy (A.M., G.G.).

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http://dx.doi.org/10.1124/jpet.113.207605DOI Listing
October 2013

Ipilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancer.

Pharmacol Res 2012 Jan 10;65(1):9-22. Epub 2011 Sep 10.

Pharmacology and Medical Oncology Section, Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.phrs.2011.09.002DOI Listing
January 2012

Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1.

Mutat Res 2011 Jul 5;712(1-2):40-8. Epub 2011 May 5.

Department of Public Health and Cell Biology, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2011.04.006DOI Listing
July 2011

Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB.

Int J Oncol 2011 Jan;38(1):241-7

Laboratory of Molecular Oncology, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy.

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January 2011

Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells.

Biochem Pharmacol 2011 Jan 25;81(2):194-202. Epub 2010 Sep 25.

Department of Structural and Functional Biology, University Federico II of Naples, Italy.

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http://dx.doi.org/10.1016/j.bcp.2010.09.019DOI Listing
January 2011

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

Nucleic Acids Res 2009 Nov 18;37(20):6849-58. Epub 2009 Sep 18.

Department of Biology, University of Rome Tor Vergata, CNR National Research Council, INFM National Institute for the Physics of Matter, Rome 00133, Italy.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkp669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777420PMC
November 2009

Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.

Mutat Res 2009 May 21;664(1-2):39-47. Epub 2009 Feb 21.

Department of Public Health and Cellular Biology, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2009.02.005DOI Listing
May 2009

Recent approaches to improve the antitumor efficacy of temozolomide.

Curr Med Chem 2009 ;16(2):245-57

Department of Neuroscience, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.2174/092986709787002718DOI Listing
March 2009

Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.

Eur J Cancer 2008 Sep 3;44(13):1914-21. Epub 2008 Aug 3.

Laboratory of Molecular Oncology, Istituto Dermopatico dell'Immacolata-IRCCS, Via dei Monti di Creta 104, 00167 Rome, Italy.

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http://dx.doi.org/10.1016/j.ejca.2008.06.032DOI Listing
September 2008

Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells.

Int J Oncol 2008 Jun;32(6):1293-303

Institute of Histology and Embryology, Faculty of Medicine, Catholic University of the Sacred Heart, 00168 Rome, Italy.

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http://dx.doi.org/10.3892/ijo_32_6_1293DOI Listing
June 2008

The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma.

Oncol Rep 2008 Apr;19(4):1039-43

Department of Neuroscience, University of Rome Tor Vergata, 00133 Rome, Italy.

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April 2008

Incidence of parenterally transmitted acute viral hepatitis among healthcare workers in Italy.

Infect Control Hosp Epidemiol 2007 May 12;28(5):629-32. Epub 2007 Apr 12.

National Centre of Epidemiology Surveillance and Health Promotion, Istituto Superiore di Sanità, Viale Regina Elena, 299-00161 Rome, Italy.

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http://dx.doi.org/10.1086/513728DOI Listing
May 2007

Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk?

Pharmacol Res 2007 May 3;55(5):359-69. Epub 2007 Feb 3.

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.phrs.2007.01.020DOI Listing
May 2007

Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype.

Mol Cell Endocrinol 2007 Jan 9;264(1-2):44-9. Epub 2006 Nov 9.

Pharmacology and Medical Oncology Section, Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.mce.2006.10.006DOI Listing
January 2007

Corticotropin-releasing hormone receptor-1 in human endometrial cancer.

Oncol Rep 2006 Feb;15(2):375-9

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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February 2006

Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.

Eur J Cancer 2005 Dec 8;41(18):2948-57. Epub 2005 Nov 8.

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.ejca.2005.08.027DOI Listing
December 2005

Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin.

Mutat Res 2006 Feb 1;594(1-2):63-77. Epub 2005 Sep 1.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier 1, Rome 00133, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.07.011DOI Listing
February 2006

Clinical perspectives of PARP inhibitors.

Pharmacol Res 2005 Jul;52(1):109-18

Department of Neuroscience, University of Rome Tor Vergata,Via Montpellier, 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.phrs.2005.02.013DOI Listing
July 2005

Chemopotentiation by PARP inhibitors in cancer therapy.

Pharmacol Res 2005 Jul;52(1):25-33

Department of Neuroscience, University of Rome, Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.phrs.2005.02.010DOI Listing
July 2005

PARP-1 inhibition to treat cancer, ischemia, inflammation.

Pharmacol Res 2005 Jul;52(1):1-4

Department of Neuroscience, Pharmacology Section, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.phrs.2005.02.007DOI Listing
July 2005

N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity.

Mol Pharmacol 2005 Feb 17;67(2):572-81. Epub 2004 Nov 17.

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1124/mol.104.004937DOI Listing
February 2005

Primary cultures of microglial cells for testing toxicity of anticancer drugs.

Toxicol Lett 2004 Mar;148(1-2):91-4

Institute of Pharmacology, Catholic University Medical School, Largo Francesco Vito 1, Rome 00168, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2003.12.058DOI Listing
March 2004

Valproic acid increases the stimulatory effect of estrogens on proliferation of human endometrial adenocarcinoma cells.

Endocrinology 2003 Jul;144(7):2822-8

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1210/en.2002-0180DOI Listing
July 2003

Pharmacological strategies to increase the antitumor activity of methylating agents.

Curr Med Chem 2002 Jul;9(13):1285-301

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133, Italy.

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http://dx.doi.org/10.2174/0929867023369916DOI Listing
July 2002

Stem cell factor activates telomerase in mouse mitotic spermatogonia and in primordial germ cells.

J Cell Sci 2002 Apr;115(Pt 8):1643-9

Dipartimento di Sanita' Pubblica e Biologia Cellulare, Sezione di Anatomia, Rome, Italy.

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April 2002

Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.

Cancer Chemother Pharmacol 2002 Mar 22;49(3):217-24. Epub 2002 Jan 22.

Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://link.springer.com/10.1007/s00280-001-0409-z
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http://dx.doi.org/10.1007/s00280-001-0409-zDOI Listing
March 2002

Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors.

Pharmacol Res 2002 Feb;45(2):73-85

Pharmacology Section, Department of Neuroscience, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1006/phrs.2001.0935DOI Listing
February 2002

Clinical applications of telomerase in cancer treatment.

Drug Resist Updat 2000 Jun;3(3):161-170

Section of Pharmacology, Medical Oncology, Department of Neuroscience, University of Rome 'Tor Vergata', Rome, Italy

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http://dx.doi.org/10.1054/drup.2000.0139DOI Listing
June 2000

Telomerase as a potential anticancer target: growth inhibition and genomic instability.

Drug Resist Updat 2000 Feb;3(1):3-6

Department of Neuroscience, Pharmacology, Oncology Section, University of Rome Tor Vergata, Rome, Italy

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http://dx.doi.org/10.1054/drup.2000.0115DOI Listing
February 2000