Publications by authors named "Grazia Gallo"

21Publications

Novel PARP-1 inhibitors based on a 2-propanoyl-3H-quinazolin-4-one scaffold.

Bioorg Med Chem Lett 2014 Jan 18;24(2):462-6. Epub 2013 Dec 18.

Department of Food, Environmental and Nutritional Sciences, Division of Chemistry and Molecular Biology, Università di Milano, Via Celoria 2, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2013.12.048DOI Listing
January 2014

Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.

J Med Chem 2012 Aug 26;55(15):6898-915. Epub 2012 Jul 26.

European Research Centre for Drug Discovery and Development (NatSynDrugs), Università degli Studi di Siena , Via Aldo Moro 2, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm300689cDOI Listing
August 2012

Derivatives of R-aminocarnitine without ammonium moiety as liver carnitine palmitoyltransferase I (L-CPT I) inhibitors.

ChemMedChem 2011 Nov 10;6(11):1977-80. Epub 2011 Aug 10.

Chemistry & Analytical Department, Sigma-Tau S.p.A. Via Pontina Km 30.400, 00040 Pomezia, Italy.

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http://dx.doi.org/10.1002/cmdc.201100289DOI Listing
November 2011

Non-natural macrocyclic inhibitors of histone deacetylases: design, synthesis, and activity.

J Med Chem 2010 Dec 12;53(23):8387-99. Epub 2010 Nov 12.

Department of Chemistry, Université de Montréal, P.O. Box 6128, Station Centre-ville, Montréal, QC, H3C 3J7 Canada.

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http://dx.doi.org/10.1021/jm101092uDOI Listing
December 2010

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

Rheumatology (Oxford) 2010 Dec 25;49(12):2281-9. Epub 2010 Aug 25.

Cytometry and B-cell Development Unit, Research Center, Department of Nephrology and Urology, Children Hospital Bambino Gesù, and Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1093/rheumatology/keq226DOI Listing
December 2010

Vorinostat-like molecules as structural, stereochemical, and pharmacological tools.

ACS Med Chem Lett 2010 May 11;1(2):70-4. Epub 2010 Mar 11.

Sigma-Tau Research & Development, Via Pontina Km 30.400, I-00040 Pomezia, Roma, Italy.

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http://dx.doi.org/10.1021/ml100028gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007911PMC
May 2010

Azetidinones as zinc-binding groups to design selective HDAC8 inhibitors.

ChemMedChem 2009 Dec;4(12):1991-2001

Dipartimento di Chimica G. Ciamician, Università of Bologna, Via Selmi 2, 40126 Bologna, Italy.

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http://dx.doi.org/10.1002/cmdc.200900309DOI Listing
December 2009

Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases.

J Biol Chem 2009 Oct 13;284(41):28093-103. Epub 2009 Aug 13.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1074/jbc.M109.004465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788860PMC
October 2009

Fibroblast growth factor 2-antagonist activity of a long-pentraxin 3-derived anti-angiogenic pentapeptide.

J Cell Mol Med 2010 Aug 20;14(8):2109-21. Epub 2010 Jul 20.

Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, Italy.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00855.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823002PMC
August 2010

Synthesis and biological activity of fluorinated combretastatin analogues.

J Med Chem 2008 May 9;51(9):2708-21. Epub 2008 Apr 9.

R&D, Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Via Pontina Km 30.400, 00040 Pomezia, Italy.

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http://dx.doi.org/10.1021/jm701362mDOI Listing
May 2008

Synthesis of benzo[1,2-d;3,4-d']diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists.

Org Biomol Chem 2007 Aug;5(16):2567-71

Institute of Medicinal Chemistry, University of Urbino "Carlo Bo", Piazza del Rinascimento 6, 61029 Urbino PU, Italy.

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http://dx.doi.org/10.1039/b707599eDOI Listing
August 2007

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.

J Leukoc Biol 2007 Oct 4;82(4):801-10. Epub 2007 Jun 4.

Department of Public Health and Cell Biology, University of Rome "Tor Vergata," Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1189/jlb.1206746DOI Listing
October 2007

Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B.

J Biol Chem 2005 Apr 8;280(16):15809-14. Epub 2005 Mar 8.

Department of Public Health and Cell Biology, University of Rome "Tor Vergata," 00173 Rome, Italy.

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http://dx.doi.org/10.1074/jbc.C400613200DOI Listing
April 2005