Grant Morahan

Grant Morahan

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Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human.

Front Genet 2019 2;10:288. Epub 2019 Apr 2.

School of Biomedical Sciences, The University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.3389/fgene.2019.00288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455049PMC
April 2019

Common Heritable Immunological Variations Revealed in Genetically Diverse Inbred Mouse Strains of the Collaborative Cross.

J Immunol 2019 Feb 26;202(3):777-786. Epub 2018 Dec 26.

Department of Immunology-Oncology, Maisonneuve-Rosemont Hospital, Montreal, Quebec H1T 2M4, Canada;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801247
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http://dx.doi.org/10.4049/jimmunol.1801247DOI Listing
February 2019

The development and application of Laboratory Animal Science in China.

Animal Model Exp Med 2018 Dec 21;1(4):247-249. Epub 2018 Dec 21.

Centre for Diabetes Research Harry Perkins Institute of Medical Research Perth Western Australia Australia.

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http://dx.doi.org/10.1002/ame2.12047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388048PMC
December 2018

Electrokinetic potential-stabilization by bile acid-microencapsulating formulation of pancreatic β-cells cultured in high ratio poly-L-ornithine-gel hydrogel colloidal dispersion: applications in cell-biomaterials, tissue engineering and biotechnological applications.

Artif Cells Nanomed Biotechnol 2018 Sep 4;46(6):1156-1162. Epub 2017 Aug 4.

a Biotechnology and Drug Development Research Laboratory, School of Pharmacy , Curtin Health Innovation Research Institute, Curtin University , Perth , WA , Australia.

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https://www.tandfonline.com/doi/full/10.1080/21691401.2017.1
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http://dx.doi.org/10.1080/21691401.2017.1362416DOI Listing
September 2018

Genetic variation in the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway affects contact hypersensitivity responses.

J Allergy Clin Immunol 2018 Sep 12;142(3):981-984.e7. Epub 2018 Jun 12.

UQ Diamantina Institute, Translational Research Institute, University of Queensland, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.04.028DOI Listing
September 2018

Keratinocyte Sonic Hedgehog Upregulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1 Secretion.

J Invest Dermatol 2018 04 11;138(4):893-902. Epub 2017 Nov 11.

Drug Discovery Group, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.10.032DOI Listing
April 2018

The effect of molecular weights of microencapsulating polymers on viability of mouse-cloned pancreatic β-cells: biomaterials, osmotic forces and potential applications in diabetes treatment.

Pharm Dev Technol 2018 Feb 9;23(2):145-150. Epub 2017 May 9.

a Biotechnology and Drug Development Research Laboratory, School of Pharmacy , Curtin Health Innovation Research Institute, Curtin University , Perth , Western Australia , Australia.

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http://dx.doi.org/10.1080/10837450.2017.1321664DOI Listing
February 2018

Complex Trait Analyses of the Collaborative Cross: Tools and Databases.

Methods Mol Biol 2017 ;1488:121-129

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, The University of Western Australia, 6 Verdun Street, Nedlands, WA, 6009, Australia.

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http://link.springer.com/10.1007/978-1-4939-6427-7_5
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http://dx.doi.org/10.1007/978-1-4939-6427-7_5DOI Listing
January 2018

Using Systems Genetics to Understanding the Etiology of Complex Disease.

Methods Mol Biol 2017 ;1488:597-606

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, The University of Western Australia, 6 Verdun Street, Nedlands, WA, 6009, Australia.

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http://dx.doi.org/10.1007/978-1-4939-6427-7_29DOI Listing
January 2018

Variable cardiac α-actin (Actc1) expression in early adult skeletal muscle correlates with promoter methylation.

Biochim Biophys Acta Gene Regul Mech 2017 Oct 26;1860(10):1025-1036. Epub 2017 Aug 26.

Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands, Western Australia, Australia; School of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Western Australia, QEII Medical Centre, Nedlands, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2017.08.004DOI Listing
October 2017

Alginate-combined cholic acid increased insulin secretion of microencapsulated mouse cloned pancreatic β cells.

Ther Deliv 2017 Oct;8(10):833-842

Biotechnology & Drug Development Research Laboratory, School of Pharmacy, Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia.

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http://dx.doi.org/10.4155/tde-2017-0042DOI Listing
October 2017

New Biotechnological Microencapsulating Methodology Utilizing Individualized Gradient-Screened Jet Laminar Flow Techniques for Pancreatic β-Cell Delivery: Bile Acids Support Cell Energy-Generating Mechanisms.

Mol Pharm 2017 08 17;14(8):2711-2718. Epub 2017 Jul 17.

Biotechnology and Drug Development Research Laboratory, School of Pharmacy, Curtin Health Innovation Research Institute, Curtin University , Perth, Western Australia 6102, Australia.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00220DOI Listing
August 2017

Innovative Microcapsules for Pancreatic β-Cells Harvested from Mature Double-Transgenic Mice: Cell Imaging, Viability, Induced Glucose-Stimulated Insulin Measurements and Proinflammatory Cytokines Analysis.

Pharm Res 2017 06 13;34(6):1217-1223. Epub 2017 Mar 13.

Biotechnology and Drug Development Research Laboratory, School of Pharmacy, Curtin Health Innovation Research Institute (CHIRI), Curtin University, Perth, WA, Australia.

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http://dx.doi.org/10.1007/s11095-017-2138-yDOI Listing
June 2017

Effects of Type 1 Diabetes Risk Alleles on Immune Cell Gene Expression.

Genes (Basel) 2017 Jun 21;8(6). Epub 2017 Jun 21.

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Nedlands, WA 6009, Australia.

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http://dx.doi.org/10.3390/genes8060167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485531PMC
June 2017

Narrow-leafed lupin (Lupinus angustifolius L.) β-conglutin proteins modulate the insulin signaling pathway as potential type 2 diabetes treatment and inflammatory-related disease amelioration.

Mol Nutr Food Res 2017 05 13;61(5). Epub 2017 Feb 13.

Plant Reproductive Biology Laboratory; Deptartment of Biochemistry, Cell & Molecular Biology of Plants, Estacion Experimental del Zaidin, Spanish National Research Council (CSIC), Granada, Spain.

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http://dx.doi.org/10.1002/mnfr.201600819DOI Listing
May 2017

Differentiation of Islet Progenitors Regulated by Nicotinamide into Transcriptome-Verified β Cells That Ameliorate Diabetes.

Stem Cells 2017 05 23;35(5):1341-1354. Epub 2017 Feb 23.

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, and Centre for Medical Research.

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http://dx.doi.org/10.1002/stem.2567DOI Listing
May 2017

A mutation in the Cdon gene potentiates congenital nevus development mediated by NRAS(Q61K).

Pigment Cell Melanoma Res 2016 07;29(4):459-64

QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.

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http://dx.doi.org/10.1111/pcmr.12487DOI Listing
July 2016

Insulin-secreting β cells require a post-genomic concept.

World J Diabetes 2016 May;7(10):198-208

Fang-Xu Jiang, Islet Cell Development Program, Harry Perkins Institute of Medical Research, Nedlands, WA 6009, Australia.

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http://dx.doi.org/10.4239/wjd.v7.i10.198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873311PMC
May 2016

Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility.

J Immunol 2016 Apr 24;196(7):3043-53. Epub 2016 Feb 24.

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Nedlands, Western Australia 6009, Australia; Centre of Medical Research, University of Western Australia, Nedlands, Western Australia 6009, Australia;

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http://dx.doi.org/10.4049/jimmunol.1502056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799766PMC
April 2016

Designing anti-diabetic β-cells microcapsules using polystyrenic sulfonate, polyallylamine, and a tertiary bile acid: Morphology, bioenergetics, and cytokine analysis.

Biotechnol Prog 2016 03 23;32(2):501-9. Epub 2016 Jan 23.

Harry Perkins Inst. of Medical Research, Centre for Diabetes Research, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1002/btpr.2223DOI Listing
March 2016

A genome-wide association study reveals susceptibility loci for myocardial infarction/coronary artery disease in Saudi Arabs.

Atherosclerosis 2016 Feb 22;245:62-70. Epub 2015 Nov 22.

Genetics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.11.019DOI Listing
February 2016

Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice.

J Endocrinol 2016 Jan 22;228(1):61-73. Epub 2015 Oct 22.

Department of Medicine (AH)Austin Hospital, University of Melbourne, Level 7, Lance Townsend Building, Studley Road, Heidelberg, Victoria 3084, AustraliaWalter and Eliza Hall Institute of Medical ResearchParkville, 3010 Victoria, AustraliaHarry Perkins Institute of Medical ResearchNedlands, Western Australia 6009, AustraliaThe School of Medical Sciences Edith Cowan UniversityJoondalup Western Australia 6027, Australia.

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http://joe.endocrinology-journals.org/content/early/2015/10/
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http://joe.endocrinology-journals.org/lookup/doi/10.1530/JOE
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http://dx.doi.org/10.1530/JOE-15-0290DOI Listing
January 2016

Multipotent pancreas progenitors: Inconclusive but pivotal topic.

World J Stem Cells 2015 Dec;7(11):1251-61

Fang-Xu Jiang, Islet Cell Development Program, Harry Perkins Institute of Medical Research, Nedlands, WA 6009, Australia.

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http://dx.doi.org/10.4252/wjsc.v7.i11.1251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691693PMC
December 2015

Transcriptome of pancreas-specific Bmpr1a-deleted islets links to TPH1-5-HT axis.

Biol Open 2015 Jul 17;4(8):1016-23. Epub 2015 Jul 17.

The Walter & Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1242/bio.011858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542282PMC
July 2015

Characterization of Retinal Vascular and Neural Damage in a Novel Model of Diabetic Retinopathy.

Invest Ophthalmol Vis Sci 2015 Jun;56(6):3721-30

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, University of Western Australia, Nedlands, Western Australia, Australia 2Centre of Medical Research, University of Western Australia, Nedlands, Western Australia, Australia.

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http://dx.doi.org/10.1167/iovs.14-16289DOI Listing
June 2015

Pancreatic stem cells remain unresolved.

Stem Cells Dev 2014 Dec 20;23(23):2803-12. Epub 2014 Oct 20.

1 Islet Cell Development Program, Harry Perkins Institute of Medical Research, and Centre for Medical Research, The University of Western Australia , Perth, Australia .

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http://dx.doi.org/10.1089/scd.2014.0214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235979PMC
December 2014

Rapid identification of major-effect genes using the collaborative cross.

Genetics 2014 Sep;198(1):75-86

Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Nedlands 6009, WA, Australia Centre of Medical Research, University of Western Australia, Nedlands 6009, WA, Australia

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http://dx.doi.org/10.1534/genetics.114.163014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174955PMC
September 2014

Comparison of sequence variants in transcriptomic control regions across 17 mouse genomes.

Database (Oxford) 2014 18;2014:bau020. Epub 2014 Mar 18.

Centre for Diabetes Research, The Western Australian Institute for Medical Research, Western Australia, Australia, Centre of Medical Research, University of Western Australia, Perth, Western Australia, Australia and Southern Cross Plant Science, Southern Cross University, Lismore, New South Wales, Australia.

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http://dx.doi.org/10.1093/database/bau020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958616PMC
August 2014

Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade.

Chem Biol Interact 2014 Jul 9;218:99-106. Epub 2014 May 9.

The MOE Key Laboratory for Standardization of Chinese Medicines and Shanghai Key Laboratory of Complex Prescription, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.04.020DOI Listing
July 2014

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.

Proc Natl Acad Sci U S A 2014 Jul 30;111(28):10305-10. Epub 2014 Jun 30.

Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark,Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; and

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http://dx.doi.org/10.1073/pnas.1402571111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104872PMC
July 2014

The stretcher spontaneous neurodegenerative mutation models Charcot-Marie-Tooth disease type 4D.

F1000Res 2013 13;2:46. Epub 2013 Feb 13.

Western Australian Institute for Medical Research and Centre for Diabetes Research, University of Western Australia, Perth, 6000, Australia ; Centre for Medical Research, University of Western Australia, Perth, 6000, Australia ; The Walter and Eliza Hall Institute of Medical Research, Victoria, 3065, Australia.

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http://dx.doi.org/10.12688/f1000research.2-46.v1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976107PMC
April 2014

Antigen-based vaccination and prevention of type 1 diabetes.

Curr Diab Rep 2013 Oct;13(5):616-23

Walter & Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, Victoria, Australia,

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http://dx.doi.org/10.1007/s11892-013-0415-7DOI Listing
October 2013

Definition of high-risk type 1 diabetes HLA-DR and HLA-DQ types using only three single nucleotide polymorphisms.

Diabetes 2013 Jun 1;62(6):2135-40. Epub 2013 Feb 1.

Centre for Diabetes Research, The Western Australian Institute for Medical Research, Perth, Western Australia, Australia.

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http://dx.doi.org/10.2337/db12-1398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661605PMC
June 2013

No association between IL12B gene polymorphisms and Graves' disease in the Chinese population.

Endocr Res 2012 23;37(4):182-7. Epub 2012 May 23.

Department of Endocrinology, First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi Province, PR China.

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http://dx.doi.org/10.3109/07435800.2012.663846DOI Listing
March 2013

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.

Diabetes 2012 Nov 13;61(11):3012-7. Epub 2012 Aug 13.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Department of Medical Genetics, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.2337/db11-1694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478521PMC
November 2012

Status and access to the Collaborative Cross population.

Mamm Genome 2012 Oct 31;23(9-10):706-12. Epub 2012 Jul 31.

Department of Computer Science, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s00335-012-9410-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463789PMC
October 2012

Pancreatic stem cells: from possible to probable.

Stem Cell Rev 2012 Sep;8(3):647-57

Centre for Diabetes Research, Western Australian Institute for Medical Research, The University of Western Australia, 50 Murray St (Rear), Perth, WA 6000, Australia.

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http://link.springer.com/10.1007/s12015-011-9333-8
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http://dx.doi.org/10.1007/s12015-011-9333-8DOI Listing
September 2012

Directed differentiation of embryonic stem cells allows exploration of novel transcription factor genes for pancreas development.

Stem Cell Rev 2012 Sep;8(3):803-12

Centre for Diabetes Research, The Western Australian Institute for Medical Research, University of Western Australia, 50 Murray St (Rear), Perth, WA 6000, Australia.

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http://link.springer.com/10.1007/s12015-011-9346-3
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http://dx.doi.org/10.1007/s12015-011-9346-3DOI Listing
September 2012

Proteomic characterization of the possible molecular targets of pyrrolizidine alkaloid isoline-induced hepatotoxicity.

Environ Toxicol Pharmacol 2012 Sep 6;34(2):608-617. Epub 2012 Jul 6.

The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201210, China; Shanghai R&D Centre for Standardization of Chinese Medicines, Shanghai, 201210, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13826689120009
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http://dx.doi.org/10.1016/j.etap.2012.06.013DOI Listing
September 2012

Insights into type 1 diabetes provided by genetic analyses.

Authors:
Grant Morahan

Curr Opin Endocrinol Diabetes Obes 2012 Aug;19(4):263-70

Centre for Diabetes Research, The Western Australian Institute for Medical Research, University of Western Australia, Perth, Western Australia, Australia.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MED.0b013e328355b7feDOI Listing
August 2012

Genetic analysis of iron-deficiency effects on the mouse spleen.

Mamm Genome 2011 Oct 6;22(9-10):556-62. Epub 2011 Jul 6.

Department of Biobehavioral Health, The Pennsylvania State University, 315 E. Health and Human Development Building, University Park, PA 16802, USA.

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http://dx.doi.org/10.1007/s00335-011-9344-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179527PMC
October 2011

Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells.

Mol Carcinog 2011 Aug 11;50(8):580-91. Epub 2011 Feb 11.

The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, China.

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http://dx.doi.org/10.1002/mc.20741DOI Listing
August 2011

Ndrg1 in development and maintenance of the myelin sheath.

Neurobiol Dis 2011 Jun 12;42(3):368-80. Epub 2011 Feb 12.

Department of Clinical Neurosciences, Institute of Neurology, UCL, London NW3 2PF, UK.

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http://dx.doi.org/10.1016/j.nbd.2011.01.030DOI Listing
June 2011

The clinical presentation of autoimmune thyroid disease in men is associated with IL12B genotype.

Clin Endocrinol (Oxf) 2011 Apr;74(4):508-12

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.

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http://doi.wiley.com/10.1111/j.1365-2265.2010.03970.x
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http://dx.doi.org/10.1111/j.1365-2265.2010.03970.xDOI Listing
April 2011

Quantification of insulin gene expression during development of pancreatic islet cells.

Pancreas 2010 Mar;39(2):201-8

Centre for Diabetes Research, Western Australian Institute for Medical Research, Perth, Australia.

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http://dx.doi.org/10.1097/MPA.0b013e3181bab68fDOI Listing
March 2010

The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance.

Endocrinology 2010 Jan 11;151(1):96-102. Epub 2009 Nov 11.

University of Melbourne, Department of Medicine, Heidelberg Repatriation Hospital, Heidelberg Heights, Victoria 3081, Australia.

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http://dx.doi.org/10.1210/en.2009-0887DOI Listing
January 2010

An NZW-derived interval on chromosome 7 moderates sialadenitis, but not insulitis in congenic nonobese diabetic mice.

J Immunol 2010 Jan 9;184(2):859-68. Epub 2009 Dec 9.

The Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.0903149DOI Listing
January 2010

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Nat Genet 2009 Jun 10;41(6):703-7. Epub 2009 May 10.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://www.nature.com/articles/ng.381
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http://dx.doi.org/10.1038/ng.381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889014PMC
June 2009

Potential of small molecule protein tyrosine kinase inhibitors as immuno-modulators and inhibitors of the development of type 1 diabetes.

ScientificWorldJournal 2009 Mar 31;9:224-8. Epub 2009 Mar 31.

Diabetes and Cell Biology Laboratory, BakerIDI Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.

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http://www.hindawi.com/journals/tswj/2009/656471/abs/
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http://dx.doi.org/10.1100/tsw.2009.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823116PMC
March 2009

Systems genetics can provide new insights in to immune regulation and autoimmunity.

J Autoimmun 2008 Nov 3;31(3):233-6. Epub 2008 Jun 3.

The University of Western Australia, Perth, WA 6000, Australia.

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http://dx.doi.org/10.1016/j.jaut.2008.04.011DOI Listing
November 2008

Type 1 diabetes: lessons for other autoimmune diseases?

J Autoimmun 2008 Nov 16;31(3):306-10. Epub 2008 Jun 16.

The Walter & Eliza Hall Institute of Medical Research, Parkville 3050, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jaut.2008.04.026DOI Listing
November 2008

The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes.

Diabetes Care 2008 Aug 16;31(8):1546-9. Epub 2008 May 16.

Autoimmunity and Transplantation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.2337/dc08-0239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494654PMC
August 2008

Establishment of "The Gene Mine": a resource for rapid identification of complex trait genes.

Mamm Genome 2008 Jun 21;19(6):390-3. Epub 2008 Aug 21.

Centre for Diabetes Research, The Western Australian Institute for Medical Research, and Centre for Medical Research, University of Western Australia, MRF Building, Level 6, 50 Murray St., Perth, WA 6000, Australia.

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http://dx.doi.org/10.1007/s00335-008-9134-9DOI Listing
June 2008

Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.

Proc Natl Acad Sci U S A 2008 Jan 14;105(3):961-6. Epub 2008 Jan 14.

Medical Research Council/Juvenile Diabetes Research Foundation Centre Development in Stem Cell Biology, Institute for Stem Cell Research and Centre for Regenerative Medicine, University of Edinburgh, King's Buildings, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0711170105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242700PMC
January 2008

Systems genetics: the next generation in genetics research?

Novartis Found Symp 2007 ;281:181-8; discussion 188-91, 208-9

Centre for Diabetes Research, The Western Australian Institute for Medical Research, University of Western Australia, Perth, WA 6000, Australia.

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December 2007

Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.

Neurochem Res 2007 Jul 2;32(7):1099-112. Epub 2007 Feb 2.

Laboratory of Neurobehavioral Genetics, Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1007/s11064-006-9234-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595145PMC
July 2007

Ventral tegmental transcriptome response to intermittent nicotine treatment and withdrawal in BALB/cJ, C57BL/6ByJ, and quasi-congenic RQI mice.

Neurochem Res 2007 Mar;32(3):457-80

Laboratory of Neurobehavioral Genetics, Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1007/s11064-006-9250-4DOI Listing
March 2007

Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.

Proc Natl Acad Sci U S A 2006 Oct 19;103(44):16430-5. Epub 2006 Oct 19.

Autoimmunity and Transplantation Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1073/pnas.0607380103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618309PMC
October 2006

The Type 1 Diabetes Genetics Consortium.

Ann N Y Acad Sci 2006 Oct;1079:1-8

Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1196/annals.1375.001DOI Listing
October 2006

IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS.

Immunol Cell Biol 2006 Apr;84(2):227-32

Centre for Immunology and Cancer Research, Princes Alexandra Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/j.1440-1711.2006.01419.xDOI Listing
April 2006

Diabetes induces Na/H exchange activity and hypertrophy of rat mesenteric but not basilar arteries.

Diabetes Res Clin Pract 2005 Dec 8;70(3):201-8. Epub 2005 Jun 8.

Adult Stem Cell Biology Laboratory, Department of Medicine, St Vincents Hospital, University of Melbourne, Fitzroy, Australia.

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http://dx.doi.org/10.1016/j.diabres.2005.03.038DOI Listing
December 2005

Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.

Diabetes 2005 Dec;54(12):3453-7

Genetics and Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050 Australia.

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http://dx.doi.org/10.2337/diabetes.54.12.3453DOI Listing
December 2005

Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development.

Int Immunol 2005 Mar 31;17(3):307-14. Epub 2005 Jan 31.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1093/intimm/dxh210DOI Listing
March 2005

Alleles of the IL12B 3'UTR associate with late onset of type 1 diabetes.

Hum Immunol 2004 Dec;65(12):1432-6

School of Surgery and Pathology, University of Western Australia; Nedlands, Australia.

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http://dx.doi.org/10.1016/j.humimm.2004.09.001DOI Listing
December 2004

The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Authors:
Gary A Churchill David C Airey Hooman Allayee Joe M Angel Alan D Attie Jackson Beatty William D Beavis John K Belknap Beth Bennett Wade Berrettini Andre Bleich Molly Bogue Karl W Broman Kari J Buck Ed Buckler Margit Burmeister Elissa J Chesler James M Cheverud Steven Clapcote Melloni N Cook Roger D Cox John C Crabbe Wim E Crusio Ariel Darvasi Christian F Deschepper R W Doerge Charles R Farber Jiri Forejt Daniel Gaile Steven J Garlow Hartmut Geiger Howard Gershenfeld Terry Gordon Jing Gu Weikuan Gu Gerald de Haan Nancy L Hayes Craig Heller Heinz Himmelbauer Robert Hitzemann Kent Hunter Hui-Chen Hsu Fuad A Iraqi Boris Ivandic Howard J Jacob Ritsert C Jansen Karl J Jepsen Dabney K Johnson Thomas E Johnson Gerd Kempermann Christina Kendziorski Malak Kotb R Frank Kooy Bastien Llamas Frank Lammert Jean-Michel Lassalle Pedro R Lowenstein Lu Lu Aldons Lusis Kenneth F Manly Ralph Marcucio Doug Matthews Juan F Medrano Darla R Miller Guy Mittleman Beverly A Mock Jeffrey S Mogil Xavier Montagutelli Grant Morahan David G Morris Richard Mott Joseph H Nadeau Hiroki Nagase Richard S Nowakowski Bruce F O'Hara Alexander V Osadchuk Grier P Page Beverly Paigen Kenneth Paigen Abraham A Palmer Huei-Ju Pan Leena Peltonen-Palotie Jeremy Peirce Daniel Pomp Michal Pravenec Daniel R Prows Zhonghua Qi Roger H Reeves John Roder Glenn D Rosen Eric E Schadt Leonard C Schalkwyk Ze'ev Seltzer Kazuhiro Shimomura Siming Shou Mikko J Sillanpää Linda D Siracusa Hans-Willem Snoeck Jimmy L Spearow Karen Svenson Lisa M Tarantino David Threadgill Linda A Toth William Valdar Fernando Pardo-Manuel de Villena Craig Warden Steve Whatley Robert W Williams Tim Wiltshire Nengjun Yi Dabao Zhang Min Zhang Fei Zou

Nat Genet 2004 Nov;36(11):1133-7

The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1038/ng1104-1133DOI Listing
November 2004

Insulin expressing hepatocytes not destroyed in transgenic NOD mice.

J Autoimmune Dis 2004 Nov 8;1(1). Epub 2004 Nov 8.

Diabetes Transplant Unit, Prince of Wales Hospital, The University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1186/1740-2557-1-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544947PMC
November 2004

Persistence of recipient lymphocytes in NOD mice after irradiation and bone marrow transplantation.

J Autoimmun 2004 Mar;22(2):131-8

Autoimmunity and Transplantation Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jaut.2003.12.003DOI Listing
March 2004

The nature and identification of quantitative trait loci: a community's view.

Nat Rev Genet 2003 Nov;4(11):911-6

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http://dx.doi.org/10.1038/nrg1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063446PMC
November 2003

A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice.

Diabetes 2003 Jan;52(1):218-22

Genetics and Bioinformatics Division, the Walter & Eliza Hall Institute of Medical Research, Melbourne, Australia.

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http://dx.doi.org/10.2337/diabetes.52.1.218DOI Listing
January 2003

Genetics of autoimmune diseases in humans and in animal models.

Curr Opin Immunol 2002 Dec;14(6):803-11

The Walter and Eliza Hall Institute of Medical Research, PO Royal Melbourne Hospital, Victoria 3050, Australia.

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December 2002

Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases.

AIDS 2002 Oct;16(15):2043-7

Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Australia.

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October 2002

Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children.

Lancet 2002 Aug;360(9331):455-9

The Walter and Eliza Hall Institute of Medical Research, PO Royal Melbourne Hospital, Victoria 3050, Australia.

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http://dx.doi.org/10.1016/S0140-6736(02)09676-9DOI Listing
August 2002