Grant A McArthur

Melanoma Institute Australia, The University of Sydney, Sydney, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia; Department of Medical Oncology, Royal North Shore Hospital, NSW, Australia.

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January 2021

Clinical, FDG-PET and molecular markers of immune checkpoint inhibitor response in patients with metastatic Merkel cell carcinoma.

Authors:

Alison M Weppler Andrew Pattison Prachi Bhave Paolo De Ieso Jeanette Raleigh Athena Hatzimihalis Anthony J Gill Shiva Balachander Jason Callahan Margaret Chua George Au-Yeung Grant A McArthur Rodney J Hicks Richard W Tothill Shahneen Sandhu

J Immunother Cancer 2020 10;8(2)

Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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October 2020

Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAF melanoma cells.

Authors:

Lorey K Smith Tiffany Parmenter Cathryn M Gould Piyush B Madhamshettiwar Karen E Sheppard Kaylene J Simpson Grant A McArthur

Sci Data 2020 10 12;7(1):339. Epub 2020 Oct 12.

Cancer Research Division, Peter MacCallum Cancer Centre, Parkville, Australia.

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October 2020

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.

Authors:

Eric P Kusnadi Anna S Trigos Carleen Cullinane David L Goode Ola Larsson Jennifer R Devlin Keefe T Chan David P De Souza Malcolm J McConville Grant A McArthur George Thomas Elaine Sanij Gretchen Poortinga Ross D Hannan Katherine M Hannan Jian Kang Richard B Pearson

EMBO J 2020 Nov 18;39(21):e105111. Epub 2020 Sep 18.

Peter MacCallum Cancer Centre, Melbourne, Vic, Australia.

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November 2020

Impact of initial treatment and prognostic factors on postprogression survival in BRAF-mutated metastatic melanoma treated with dacarbazine or vemurafenib ± cobimetinib: a pooled analysis of four clinical trials.

Authors:

Paolo A Ascierto Antoni Ribas James Larkin Grant A McArthur Karl D Lewis Axel Hauschild Keith T Flaherty Edward McKenna Qian Zhu Yong Mun Brigitte Dréno

J Transl Med 2020 08 3;18(1):294. Epub 2020 Aug 3.

Nantes University, 1 Place Alexis Ricordeau, 44093, Nantes Cedex 1, France.

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August 2020

Obesity and the Impact on Cutaneous Melanoma: Friend or Foe?

Authors:

Lorey K Smith Shaghayegh Arabi Emily J Lelliott Grant A McArthur Karen E Sheppard

Cancers (Basel) 2020 Jun 15;12(6). Epub 2020 Jun 15.

Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.

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June 2020

Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAF mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial.

Authors:

Ralf Gutzmer Daniil Stroyakovskiy Helen Gogas Caroline Robert Karl Lewis Svetlana Protsenko Rodrigo P Pereira Thomas Eigentler Piotr Rutkowski Lev Demidov Georgy Moiseevich Manikhas Yibing Yan Kuan-Chieh Huang Anne Uyei Virginia McNally Grant A McArthur Paolo A Ascierto

Lancet 2020 06;395(10240):1835-1844

Istituto Nazionale Tumori IRCCS Fondazione G Pascale, Naples, Italy.

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June 2020

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.

Nat Commun 2020 05 26;11(1):2641. Epub 2020 May 26.

Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC, 3000, Australia.

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May 2020

F-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma.

Authors:

Annie Wong Jason Callahan Marleen Keyaerts Bart Neyns Johanna Mangana Susanne Aberle Alan Herschtal Sonia Fullerton Donna Milne Amir Iravani Grant A McArthur Rodney J Hicks

Cancer Imaging 2020 May 14;20(1):36. Epub 2020 May 14.

Research Division, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC, 3000, Australia.

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May 2020

Efficacy of immune checkpoint inhibitors for in-transit melanoma.

Authors:

Emilia Nan Tie Julia Lai-Kwon Michael Alexander Rtshiladze Lumine Na James Bozzi Tavis Read Victoria Atkinson George Au-Yeung Georgina V Long Grant A McArthur Shahneen Sandhu Robyn Saw Euan Walpole Alexander Menzies Mark Smithers David E Gyorki

J Immunother Cancer 2020 05;8(1)

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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May 2020

Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma.

J Immunother Cancer 2020 04;8(1)

Ludwig Institute for Cancer Research Austin Branch, Heidelberg, Victoria, Australia.

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April 2020

Survival of patients with advanced metastatic melanoma: The impact of MAP kinase pathway inhibition and immune checkpoint inhibition - Update 2019.

Authors:

Selma Ugurel Joachim Röhmel Paolo A Ascierto Jürgen C Becker Keith T Flaherty Jean J Grob Axel Hauschild James Larkin Elisabeth Livingstone Georgina V Long Paul Lorigan Grant A McArthur Antoni Ribas Caroline Robert Lisa Zimmer Dirk Schadendorf Claus Garbe

Eur J Cancer 2020 05 13;130:126-138. Epub 2020 Mar 13.

Center for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany.

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May 2020

Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in -Mutant Melanoma.

Authors:

Antoni Ribas Adil Daud Anna C Pavlick Rene Gonzalez Karl D Lewis Omid Hamid Thomas F Gajewski Igor Puzanov Matthew Wongchenko Isabelle Rooney Jessie J Hsu Yibing Yan Erica Park Grant A McArthur

Clin Cancer Res 2020 01 15;26(1):46-53. Epub 2019 Nov 15.

Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, and University of Melbourne, Parkville, Victoria, Australia.

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January 2020

A Distinct Pretreatment Immune Gene Signature in Lentigo Maligna Is Associated with Imiquimod Response.

Authors:

Heloise Halse Franco Caramia Catriona A McLean Minyu Wang Han Xian Aw Yeang Simon P Keam Andreas Behren Lena Ly Martin Haskett Jonathan Cebon Grant A McArthur Paul J Neeson Victoria J Mar

J Invest Dermatol 2020 04 30;140(4):869-877.e16. Epub 2019 Sep 30.

Victorian Melanoma Service, Alfred Hospital, Melbourne, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

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April 2020

Lymphatic and Hematogenous Dissemination in Patients With Primary Cutaneous Melanoma.

Authors:

Nikki R Adler Grant A McArthur Victoria J Mar

JAMA Dermatol 2019 Sep 11. Epub 2019 Sep 11.

School of Public Health and Preventive Medicine, Monash University, Victoria, Australia.

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September 2019

High-resolution MRI demonstrates that more than 90% of small intracranial melanoma metastases develop in close relationship to the leptomeninges.

Authors:

Arian Lasocki Chloe Khoo Peter K H Lau David L Kok Grant A Mcarthur

Neuro Oncol 2020 03;22(3):423-432

Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

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March 2020

Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.

Proc Natl Acad Sci U S A 2019 09 22;116(36):17990-18000. Epub 2019 Aug 22.

Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia;

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September 2019

Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM.

Authors:

Karl D Lewis James Larkin Antoni Ribas Keith T Flaherty Grant A McArthur Paolo A Ascierto Brigitte Dréno Yibing Yan Matthew Wongchenko Edward McKenna Qian Zhu Yong Mun Axel Hauschild

Br J Cancer 2019 10 16;121(7):522-528. Epub 2019 Aug 16.

Department of Dermatology, University Hospital Schleswig-Holstein, Kiel, D-24105, Germany.

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October 2019

Acute toxic epidermal necrolysis reaction post single dose pembrolizumab with preceding cephalosporin exposure: successful rechallenge with anti-PD-1 therapy.

Authors:

Anna J Lomax Peter I A McQuillan Anthony Hall Grant A McArthur

Intern Med J 2019 08;49(8):1051-1053

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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August 2019

Effect of concomitant dosing with acid-reducing agents and vemurafenib dose on survival in patients with BRAF mutation-positive metastatic melanoma treated with vemurafenib ± cobimetinib.

Authors:

Karl Lewis Axel Hauschild James Larkin Antoni Ribas Keith T Flaherty Grant A McArthur Brigitte Dréno Edward McKenna Qian Zhu Yong Mun Paolo A Ascierto

Eur J Cancer 2019 07 4;116:45-55. Epub 2019 Jun 4.

Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Naples, Italy.

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July 2019

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.

Authors:

Amit Khot Natalie Brajanovski Donald P Cameron Nadine Hein Kylee H Maclachlan Elaine Sanij John Lim John Soong Emma Link Piers Blombery Ella R Thompson Andrew Fellowes Karen E Sheppard Grant A McArthur Richard B Pearson Ross D Hannan Gretchen Poortinga Simon J Harrison

Cancer Discov 2019 08 15;9(8):1036-1049. Epub 2019 May 15.

Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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August 2019

Somatic Hypermutation of the Oncogene in a Human Cutaneous Melanoma.

Authors:

Xiaomeng Zhang Jian Zhong Tang Ismael A Vergara Youfang Zhang Pacman Szeto Lie Yang Christopher Mintoff Andrew Colebatch Lachlan McIntosh Katrina A Mitchell Evangeline Shaw Helen Rizos Georgina V Long Nicholas Hayward Grant A McArthur Anthony T Papenfuss Kieran F Harvey Mark Shackleton

Mol Cancer Res 2019 07 4;17(7):1435-1449. Epub 2019 Mar 4.

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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July 2019

Genomic Features of Exceptional Response in Vemurafenib ± Cobimetinib-treated Patients with -mutated Metastatic Melanoma.

Authors:

Yibing Yan Matthew J Wongchenko Caroline Robert James Larkin Paolo A Ascierto Brigitte Dréno Michele Maio Claus Garbe Paul B Chapman Jeffrey A Sosman Zhen Shi Hartmut Koeppen Jessie J Hsu Ilsung Chang Ivor Caro Isabelle Rooney Grant A McArthur Antoni Ribas

Clin Cancer Res 2019 06 1;25(11):3239-3246. Epub 2019 Mar 1.

Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, David Geffen UCLA School of Medicine, Los Angeles, California.

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June 2019

Molecular Genomic Profiling of Melanocytic Nevi.

Authors:

Andrew J Colebatch Peter Ferguson Felicity Newell Stephen H Kazakoff Tom Witkowski Alexander Dobrovic Peter A Johansson Robyn P M Saw Jonathan R Stretch Grant A McArthur Georgina V Long John F Thompson John V Pearson Graham J Mann Nicholas K Hayward Nicola Waddell Richard A Scolyer James S Wilmott

J Invest Dermatol 2019 08 14;139(8):1762-1768. Epub 2019 Feb 14.

Melanoma Institute Australia, The University of Sydney, New South Wales, Australia; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

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August 2019

Genomic Analysis of Circulating Tumor DNA Using a Melanoma-Specific UltraSEEK Oncogene Panel.

Authors:

Elin S Gray Tom Witkowski Michelle Pereira Leslie Calapre Karl Herron Darryl Irwin Brett Chapman Muhammad A Khattak Jeanette Raleigh Athena Hatzimihalis Jonathan Cebon Shahneen Sandhu Grant A McArthur Michael Millward Melanie Ziman Alexander Dobrovic Stephen Q Wong

J Mol Diagn 2019 05 5;21(3):418-426. Epub 2019 Feb 5.

Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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May 2019

A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy.

Authors:

Emily J Lelliott Carleen Cullinane Claire A Martin Rachael Walker Kelly M Ramsbottom Fernando Souza-Fonseca-Guimaraes Shatha Abuhammad Jessica Michie Laura Kirby Richard J Young Alison Slater Peter Lau Katrina Meeth Jane Oliaro Nicole Haynes Grant A McArthur Karen E Sheppard

Sci Rep 2019 02 4;9(1):1225. Epub 2019 Feb 4.

Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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February 2019

Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation.

Authors:

Jeannine Diesch Megan J Bywater Elaine Sanij Donald P Cameron William Schierding Natalie Brajanovski Jinbae Son Jirawas Sornkom Nadine Hein Maurits Evers Richard B Pearson Grant A McArthur Austen R D Ganley Justin M O'Sullivan Ross D Hannan Gretchen Poortinga

Commun Biol 2019 28;2:39. Epub 2019 Jan 28.

1Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3000 Australia.

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April 2020

Omitting radiosurgery in melanoma brain metastases: a drastic and dangerous de-escalation - Authors' reply.

Authors:

Georgina V Long Victoria Atkinson Angela Hong Grant A McArthur Alexander M Menzies

Lancet Oncol 2018 08;19(8):e367

Disciplines of Medical Oncology, Melanoma Institute Australia, University of Sydney, Sydney, NSW 2065, Australia; Royal North Shore and Mater Hospitals, Sydney, NSW, Australia.

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August 2018

Publications by authors named "Grant A McArthur"

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