Graham Simmons

Graham Simmons

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Graham Simmons

Graham Simmons

Publications by authors named "Graham Simmons"

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Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential.

Sci Rep 2019 Dec 31;9(1):20399. Epub 2019 Dec 31.

Department of Entomology, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA.

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http://dx.doi.org/10.1038/s41598-019-56551-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938517PMC
December 2019

Antiviral Functions of Monoclonal Antibodies against Chikungunya Virus.

Viruses 2019 03 28;11(4). Epub 2019 Mar 28.

Vitalant Research Institute, San Francisco, CA 94118, USA.

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http://dx.doi.org/10.3390/v11040305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520934PMC
March 2019

Susceptibility of Chikungunya Virus to Inactivation by Heat and Commercially and World Health Organization-Recommended Biocides.

J Infect Dis 2018 09;218(9):1507-1510

Institute of Experimental Virology, TWINCORE Centre for Experimental and Clinical Infection Research (a joint venture between the Medical School Hannover and the Helmholtz Centre for Infection Research), Hannover, Germany.

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https://academic.oup.com/jid/article/218/9/1507/5038988
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http://dx.doi.org/10.1093/infdis/jiy359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151073PMC
September 2018

Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane.

Cell Host Microbe 2018 09 23;24(3):417-428.e5. Epub 2018 Aug 23.

Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Pathology and Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137268PMC
September 2018

An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope.

PLoS Negl Trop Dis 2018 07 31;12(7):e0006693. Epub 2018 Jul 31.

Blood Systems Research Institute, San Francisco, CA, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0006693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086482PMC
July 2018

Arbovirus Diagnostics: From Bad to Worse due to Expanding Dengue Virus Vaccination and Zika Virus Epidemics.

Clin Infect Dis 2018 04;66(8):1181-1183

Blood Systems Research Institute, University of California, San Francisco.

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http://dx.doi.org/10.1093/cid/cix972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248677PMC
April 2018

Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins.

Curr Gene Ther 2016 ;16(1):47-55

Department of Laboratory Medicine, University of California, San Francisco, USA.

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http://dx.doi.org/10.2174/1566523216666160119093948DOI Listing
November 2016

Inhibitory Antibodies Targeting Emerging Viruses: Advancements and Mechanisms.

Clin Vaccine Immunol 2016 07 5;23(7):535-9. Epub 2016 Jul 5.

Blood Systems Research Institute, San Francisco, California, USA, and University of California, San Francisco, San Francisco, California, USAUniversity of Maryland School of Medicine

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http://dx.doi.org/10.1128/CVI.00136-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933769PMC
July 2016

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.

Cell Rep 2015 Dec 10;13(11):2553-2564. Epub 2015 Dec 10.

Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720387PMC
December 2015

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Cell 2015 Nov 6;163(5):1095-1107. Epub 2015 Nov 6.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.10.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659373PMC
November 2015

Protease inhibitors targeting coronavirus and filovirus entry.

Antiviral Res 2015 Apr 7;116:76-84. Epub 2015 Feb 7.

Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94118, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542150002
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http://dx.doi.org/10.1016/j.antiviral.2015.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774534PMC
April 2015

Human keratinocytes restrict chikungunya virus replication at a post-fusion step.

Virology 2015 Feb 8;476:1-10. Epub 2014 Dec 8.

Centre d׳étude d'agents Pathogènes et Biotechnologies pour la Santé, CPBS CNRS- UMR5236/UM1/UM2, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.11.013DOI Listing
February 2015

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease.

PLoS Negl Trop Dis 2013 12;7(9):e2423. Epub 2013 Sep 12.

Blood Systems Research Institute, San Francisco, California, United States of America ; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0002423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772074PMC
March 2014

Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.

Antiviral Res 2013 Dec 8;100(3):605-14. Epub 2013 Oct 8.

Blood Systems Research Institute, 270 Masonic Ave, San Francisco, CA 94118, United States. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2013.09.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889862PMC
December 2013

Filovirus entry.

Authors:
Graham Simmons

Adv Exp Med Biol 2013 ;790:83-94

Department of Laboratory Medicine, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-4614-7651-1_5DOI Listing
September 2013

Emerging infectious agents and the nation's blood supply: responding to potential threats in the 21st century.

Transfusion 2013 Feb 13;53(2):438-54. Epub 2012 Jun 13.

Transfusion Medicine and Cellular Therapeutics Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1111/j.1537-2995.2012.03742.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644861PMC
February 2013

Development of novel entry inhibitors targeting emerging viruses.

Expert Rev Anti Infect Ther 2012 Oct;10(10):1129-38

Blood Systems Research Institute and Department of Laboratory Medicine, University of California, San Francisco, 270 Masonic Avenue, San Francisco, CA 94118, USA.

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http://dx.doi.org/10.1586/eri.12.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587779PMC
October 2012

Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection.

J Gen Virol 2012 Aug 25;93(Pt 8):1673-1679. Epub 2012 Apr 25.

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1099/vir.0.041277-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541758PMC
August 2012

No evidence of murine leukemia virus-related viruses in live attenuated human vaccines.

PLoS One 2011 22;6(12):e29223. Epub 2011 Dec 22.

Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029223PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245253PMC
May 2012

Host genetic basis for hepatitis C virus clearance: a role for blood collection centers.

Curr Opin Hematol 2010 Nov;17(6):550-7

Blood Systems Research Institute, San Francisco, California 94118, USA.

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http://dx.doi.org/10.1097/MOH.0b013e32833e7544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069808PMC
November 2010

Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States.

Retrovirology 2010 Jul 1;7:57. Epub 2010 Jul 1.

Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

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http://dx.doi.org/10.1186/1742-4690-7-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908559PMC
July 2010

Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.

J Virol 2007 Dec 10;81(24):13378-84. Epub 2007 Oct 10.

Department of Microbiology, University of Pennsylvania School of Medicine, 225 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6076, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01170-07
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http://dx.doi.org/10.1128/JVI.01170-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168880PMC
December 2007

Proteolysis of SARS-associated coronavirus spike glycoprotein.

Adv Exp Med Biol 2006 ;581:235-40

University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

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http://dx.doi.org/10.1007/978-0-387-33012-9_39DOI Listing
December 2006

The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.

J Virol 2006 Jul;80(13):6305-17

Institute for Clinical and Molecular Virology and Nikolaus-Fiebiger-Center, University Erlangen-Nürnberg, Glückstrasse 6, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1128/JVI.02545-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488929PMC
July 2006

Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry.

J Virol 2006 Jun;80(12):5768-76

Department of Microbiology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104-6076, USA.

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http://dx.doi.org/10.1128/JVI.00442-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472567PMC
June 2006

Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide.

J Virol 2006 Jan;80(1):353-9

Department of Microbiology, University of Pennsylvania School of Medicine, 225 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6076, USA.

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http://dx.doi.org/10.1128/JVI.80.1.353-359.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317511PMC
January 2006

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry.

Proc Natl Acad Sci U S A 2005 Aug 4;102(33):11876-81. Epub 2005 Aug 4.

Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.0505577102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188015PMC
August 2005

Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes.

Emerg Infect Dis 2005 Mar;11(3):411-6

Wohl Virion Centre and Division of Infection and Immunity, University College London, 46 Cleveland St, London W1T 4JF, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298259PMC
http://dx.doi.org/10.3201/eid1103.040906DOI Listing
March 2005

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry.

Proc Natl Acad Sci U S A 2004 Mar 9;101(12):4240-5. Epub 2004 Mar 9.

Department of Microbiology, University of Pennsylvania School of Medicine, 225 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0306446101
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http://dx.doi.org/10.1073/pnas.0306446101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC384725PMC
March 2004

Identification of murine T-cell epitopes in Ebola virus nucleoprotein.

Virology 2004 Jan;318(1):224-30

Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6076, USA.

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http://dx.doi.org/10.1016/j.virol.2003.09.016DOI Listing
January 2004

Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.

J Virol 2003 Dec;77(24):13433-8

Department of Microbiology. Abramson Family Cancer Research Institute, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104-6076, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC296046PMC
http://dx.doi.org/10.1128/jvi.77.24.13433-13438.2003DOI Listing
December 2003

Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence.

J Virol 2002 Mar;76(5):2518-28

Department of Microbiology, School of Medicine, University of Pennsylvania, 303A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6076, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153797PMC
http://dx.doi.org/10.1128/jvi.76.5.2518-2528.2002DOI Listing
March 2002

T-cell line adaptation of human immunodeficiency virus type 1 strain SF162: effects on envelope, vpu and macrophage-tropism.

J Gen Virol 2000 Dec;81(Pt 12):2899-2904

The Wohl Virion Centre, Department of Immunology and Molecular Pathology, The Windeyer Institute of Medical Sciences, University College London, 46 Cleveland Street, London W1P 6DB, UK1.

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http://dx.doi.org/10.1099/0022-1317-81-12-2899DOI Listing
December 2000