Graham Lord

Graham Lord

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Graham Lord

Publications by authors named "Graham Lord"

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Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4 T Cells.

Immunity 2020 01 7;52(1):151-166.e6. Epub 2020 Jan 7.

Cancer Immunology Unit, UCL Cancer Institute, University College London, London WC1E 6DD, UK; Research Department of Haematology, University College London, Cancer Institute, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.12.007DOI Listing
January 2020

Regulatory T-cell therapy in Crohn's disease: challenges and advances.

Gut 2020 Jan 24. Epub 2020 Jan 24.

School of Immunology and Microbial Sciences, King's College London, London, UK

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http://dx.doi.org/10.1136/gutjnl-2019-319850DOI Listing
January 2020

Response to LTE 19-01163.

Gastroenterology 2019 Oct 5. Epub 2019 Oct 5.

King's College London and Guy's and St. Thomas' NHS Foundation Trust, UK; Faculty of Biology, Medicine and Health, University of Manchester, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.09.036DOI Listing
October 2019

Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α.

Gastroenterology 2019 05 30;156(6):1775-1787. Epub 2019 Jan 30.

School of Immunology and Microbial Sciences, King's College London, London, UK; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.01.025DOI Listing
May 2019

microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance.

J Clin Invest 2019 03 11;129(3):1257-1271. Epub 2019 Feb 11.

School of Immunology and Microbial Sciences, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1172/JCI124725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391082PMC
March 2019

The genetic determinants of renal allograft rejection.

Am J Transplant 2018 08 28;18(8):2100-2101. Epub 2018 May 28.

MRC Centre for Transplantation and NIHR Biomedical Research Centre at Guy's and St Thomas', NHS Foundation Trust and King's College London, London, UK.

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http://dx.doi.org/10.1111/ajt.14909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099347PMC
August 2018

Immunomodulatory role of Keratin 76 in oral and gastric cancer.

Nat Commun 2018 08 24;9(1):3437. Epub 2018 Aug 24.

Centre for Stem Cells & Regenerative Medicine, King's College London, Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK.

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http://dx.doi.org/10.1038/s41467-018-05872-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109110PMC
August 2018

Mutations Cause Congenital Nephrotic Syndrome.

J Am Soc Nephrol 2017 May 8;28(5):1614-1621. Epub 2016 Dec 8.

Bristol Renal and Children's Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom;

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http://dx.doi.org/10.1681/ASN.2016040387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407720PMC
May 2017

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients.

Transplantation 2017 03;101(3):541-547

1 King's College London, MRC Centre for Transplantation, London, United Kingdom. 2 BRC Flow Cytometry Laboratory, Guy's Hospital, London, United Kingdom. 3 NIHR Comprehensive Biomedical Research Centre at Guy's and St Thomas' Hospital, London, United Kingdom. 4 King's Health Partners, London, United Kingdom.

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http://dx.doi.org/10.1097/TP.0000000000001341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178883PMC
March 2017

Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response.

Front Immunol 2016 23;7:643. Epub 2016 Dec 23.

Department of Immune Regulation and Intervention, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.

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http://dx.doi.org/10.3389/fimmu.2016.00643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179524PMC
December 2016

Boosting translational research in the U.K.

Sci Transl Med 2016 09;8(357):357fs15

Department of Experimental Immunobiology, King's College London, London, U.K. National Institute for Health Research Biomedical Research Centre, Guy's and St. Thomas' National Health Service Foundation Trust and King's College London, London, U.K.

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http://dx.doi.org/10.1126/scitranslmed.aag1172DOI Listing
September 2016

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease.

Gut 2016 Apr 24;65(4):584-94. Epub 2015 Feb 24.

Medical Research Council Centre for Transplantation, King's College London, London, UK Department of Experimental Immunobiology, King's College London, London, UK National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2014-306919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819603PMC
April 2016

T-bet as a key regulator of mucosal immunity.

Immunology 2016 Apr 23;147(4):367-76. Epub 2016 Feb 23.

Division of Transplantation Immunology and Mucosal Biology, Department of Experimental Immunobiology, King's College London, London, UK.

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http://dx.doi.org/10.1111/imm.12575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799884PMC
April 2016

Markers of achievement for assessing and monitoring gender equity in translational research organisations: a rationale and study protocol.

BMJ Open 2016 Jan 7;6(1):e009022. Epub 2016 Jan 7.

Medical Sciences Division, University of Oxford, John Radcliffe Hospital, Oxford, UK NIHR Oxford Biomedical Research Centre, Joint Research Office, Churchill Hospital, Oxford, UK Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.

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http://bmjopen.bmj.com/content/6/1/e009022.full.pdf+html
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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2015-00902
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http://dx.doi.org/10.1136/bmjopen-2015-009022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716190PMC
January 2016

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

Gastroenterology 2015 Aug 25;149(2):456-67.e15. Epub 2015 Apr 25.

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085150057
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http://dx.doi.org/10.1053/j.gastro.2015.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539618PMC
August 2015

Immune biomarkers: the promises and pitfalls of personalized medicine.

Nat Rev Immunol 2015 May 27;15(5):323-9. Epub 2015 Mar 27.

Department of Experimental Immunobiology, Medical Research Council Centre for Transplantation, King's College London, SE1 9RT, UK, and at the National Institute for Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/nri3820DOI Listing
May 2015

The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.

Nat Rev Gastroenterol Hepatol 2015 May;12(5):271-83

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/nrgastro.2015.52DOI Listing
May 2015

Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program.

Immunity 2015 Mar 10;42(3):499-511. Epub 2015 Mar 10.

Division of Transplantation Immunology and Mucosal Biology, King's College London, London SE1 9RT, UK; Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, NH 03756, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372260PMC
March 2015

Role and species-specific expression of colon T cell homing receptor GPR15 in colitis.

Nat Immunol 2015 Feb 22;16(2):207-213. Epub 2014 Dec 22.

Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1038/ni.3079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338558PMC
February 2015

Preventing aristolochic acid nephropathy.

Clin J Am Soc Nephrol 2015 Feb 13;10(2):167-8. Epub 2015 Jan 13.

Department of Experimental Immunobiology, King's College London, London, United Kingdom; Department of Nephrology and Transplantation, Guy's and St. Thomas' National Health Service Foundation Trust, London, United Kingdom; and National Institute for Health Research Biomedical Research Centre, Guy's and St. Thomas' National Health Service Foundation Trust and King's College London, London, United Kingdom

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http://dx.doi.org/10.2215/CJN.12391214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317750PMC
February 2015

CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.

J Immunol 2015 Jan 12;194(2):505-13. Epub 2014 Dec 12.

Department of Immune Regulation and Intervention, Division of Transplantation, Immunology, and Mucosal Biology, Guy's Hospital, King's College London, London SE1 9RT, United Kingdom; Department of Microbiology and Immunology, Geisel School of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766; Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756; and.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1401553
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http://dx.doi.org/10.4049/jimmunol.1401553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282958PMC
January 2015

Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis.

PLoS One 2013 16;8(10):e75918. Epub 2013 Oct 16.

Department of Experimental Immunobiology, King's College London, London, United Kingdom ; NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075918PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797812PMC
July 2014

How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?

Expert Rev Mol Diagn 2014 Apr;14(3):249-51

Intensive Care Medicine, Guy's and St Thomas' NHS Foundation Trust (GSTFT), London, UK.

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http://dx.doi.org/10.1586/14737159.2014.899151DOI Listing
April 2014

The immune cell transcription factor T-bet: A novel metabolic regulator.

Adipocyte 2014 Jan 28;3(1):58-62. Epub 2013 Aug 28.

Division of Diabetes and Nutritional Sciences; Department of Experimental Immunobiology; King's College London; London, UK.

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http://dx.doi.org/10.4161/adip.26220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917935PMC
January 2014

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

J Immunol 2013 Dec 18;191(12):5925-32. Epub 2013 Nov 18.

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology and Medical Research Council Centre for Transplantation, Guy's Campus, King's College London, London SE1 9RT, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1202254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858236PMC
December 2013

The challenges of stratifying patients for trials in inflammatory bowel disease.

Trends Immunol 2013 Nov 10;34(11):564-71. Epub 2013 Sep 10.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://www.cell.com/trends/immunology/pdf/S1471-4906(13)0011
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http://linkinghub.elsevier.com/retrieve/pii/S147149061300119
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http://dx.doi.org/10.1016/j.it.2013.08.002DOI Listing
November 2013

T-bet: a bridge between innate and adaptive immunity.

Nat Rev Immunol 2013 Nov 11;13(11):777-89. Epub 2013 Oct 11.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nri3536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290922PMC
November 2013

Aristolochic acid nephropathy.

BMJ 2012 Jun 15;344:e4000. Epub 2012 Jun 15.

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http://dx.doi.org/10.1136/bmj.e4000DOI Listing
June 2012

Transcriptional control of natural killer cell differentiation and function.

Cell Mol Life Sci 2011 Nov 24;68(21):3495-503. Epub 2011 Aug 24.

Medical Research Council (MRC) Centre for Transplantation, Guy's Hospital, King's College London, 5th floor Tower Wing, London SE1 9RT, UK.

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http://dx.doi.org/10.1007/s00018-011-0800-9DOI Listing
November 2011

An imaging flow cytometric method for measuring cell division history and molecular symmetry during mitosis.

Cytometry A 2011 Jul 2;79(7):496-506. Epub 2011 Jun 2.

Flow Cytometry Laboratory, London Research Institute, Cancer Research UK.

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http://dx.doi.org/10.1002/cyto.a.21091DOI Listing
July 2011

Monocytes control natural killer cell differentiation to effector phenotypes.

Blood 2011 Apr 9;117(17):4511-8. Epub 2011 Mar 9.

Medical Research Council Centre for Transplantation, King's College London, London, UK.

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http://dx.doi.org/10.1182/blood-2010-10-312264DOI Listing
April 2011

Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses.

J Immunol 2011 Mar 9;186(6):3304-8. Epub 2011 Feb 9.

Medical Research Council Centre for Transplantation, King's College London, SE1 9RT London, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1004122DOI Listing
March 2011

Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice.

Int J Cancer 2011 Jan;128(1):21-32

Section of Molecular Carcinogenesis, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1002/ijc.25324DOI Listing
January 2011

Strategies for translational research in the United Kingdom.

Sci Transl Med 2010 Oct;2(53):53cm28

National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy's and St. Thomas' Hospital and King's College London, SE1 9RT London, UK.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30011
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http://dx.doi.org/10.1126/scitranslmed.3001129DOI Listing
October 2010

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells.

Nat Immunol 2010 Sep 8;11(9):862-71. Epub 2010 Aug 8.

Division of Immunology, Infection and Inflammatory Diseases, King's College London, Medical Research Council Centre for Transplantation, Guy's Hospital, London, UK.

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http://www.tara.tcd.ie/bitstream/handle/2262/50383/PEER_stag
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http://www.nature.com/doifinder/10.1038/ni.1917
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http://dx.doi.org/10.1038/ni.1917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011020PMC
September 2010

Genetic loci influencing kidney function and chronic kidney disease.

Authors:
John C Chambers Weihua Zhang Graham M Lord Pim van der Harst Debbie A Lawlor Joban S Sehmi Daniel P Gale Mark N Wass Kourosh R Ahmadi Stephan J L Bakker Jacqui Beckmann Henk J G Bilo Murielle Bochud Morris J Brown Mark J Caulfield John M C Connell H Terence Cook Ioana Cotlarciuc George Davey Smith Ranil de Silva Guohong Deng Olivier Devuyst Lambert D Dikkeschei Nada Dimkovic Mark Dockrell Anna Dominiczak Shah Ebrahim Thomas Eggermann Martin Farrall Luigi Ferrucci Jurgen Floege Nita G Forouhi Ron T Gansevoort Xijin Han Bo Hedblad Jaap J Homan van der Heide Bouke G Hepkema Maria Hernandez-Fuentes Elina Hypponen Toby Johnson Paul E de Jong Nanne Kleefstra Vasiliki Lagou Marta Lapsley Yun Li Ruth J F Loos Jian'an Luan Karin Luttropp Céline Maréchal Olle Melander Patricia B Munroe Louise Nordfors Afshin Parsa Leena Peltonen Brenda W Penninx Esperanza Perucha Anneli Pouta Inga Prokopenko Paul J Roderick Aimo Ruokonen Nilesh J Samani Serena Sanna Martin Schalling David Schlessinger Georg Schlieper Marc A J Seelen Alan R Shuldiner Marketa Sjögren Johannes H Smit Harold Snieder Nicole Soranzo Timothy D Spector Peter Stenvinkel Michael J E Sternberg Ramasamyiyer Swaminathan Toshiko Tanaka Lielith J Ubink-Veltmaat Manuela Uda Peter Vollenweider Chris Wallace Dawn Waterworth Klaus Zerres Gerard Waeber Nicholas J Wareham Patrick H Maxwell Mark I McCarthy Marjo-Riitta Jarvelin Vincent Mooser Goncalo R Abecasis Liz Lightstone James Scott Gerjan Navis Paul Elliott Jaspal S Kooner

Nat Genet 2010 May 11;42(5):373-5. Epub 2010 Apr 11.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College of London, London, UK.

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http://dx.doi.org/10.1038/ng.566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748585PMC
May 2010

T-bet, a Th1 transcription factor regulates the expression of Tim-3.

Eur J Immunol 2010 Mar;40(3):859-66

Department of Neurology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/eji.200939842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837127PMC
March 2010

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes.

Proc Natl Acad Sci U S A 2009 Oct 5;106(42):17876-81. Epub 2009 Oct 5.

MRC/UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London W1T 4JF, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0909357106
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http://dx.doi.org/10.1073/pnas.0909357106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764903PMC
October 2009

A central role for monocytes in Toll-like receptor-mediated activation of the vasculature.

Immunology 2009 Sep;128(1):58-68

Cardiovascular Research Unit, School of Medicine and Biomedical Sciences, The University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1111/j.1365-2567.2009.03071.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747139PMC
September 2009

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells.

Cancer Cell 2009 Sep;16(3):208-19

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ccr.2009.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740755PMC
September 2009

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses.

Proc Natl Acad Sci U S A 2009 Apr 26;106(15):6232-7. Epub 2009 Mar 26.

Department of Immunobiology, King's College London School of Medicine at Guy's, King's College and St. Thomas' Hospitals, London SE1 1UL, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0808144106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669354PMC
April 2009

Relative roles of Th1 and Th17 effector cells in allograft rejection.

Curr Opin Organ Transplant 2009 Feb;14(1):23-9

Department of Nephrology and Transplantation, King's College, London, UK.

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http://dx.doi.org/10.1097/MOT.0b013e32831b70c2DOI Listing
February 2009

Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

Carcinogenesis 2007 Nov 13;28(11):2253-61. Epub 2007 Apr 13.

Section of Molecular Carcinogenesis, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, UK.

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http://dx.doi.org/10.1093/carcin/bgm082DOI Listing
November 2007

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

Proc Natl Acad Sci U S A 2007 Oct 17;104(43):17034-9. Epub 2007 Oct 17.

Departments of Immunobiology and Nephrology and Transplantation, King's College London, London, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0708426104
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http://dx.doi.org/10.1073/pnas.0708426104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040448PMC
October 2007

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

Diabetes 2007 Sep 1;56(9):2242-50. Epub 2007 May 1.

Department of Medicine, Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.2337/db07-0425DOI Listing
September 2007

A strategy for translation.

Lancet 2007 May;369(9575):1771-1773

NIHR Comprehensive Biomedical Research Centre, Guy's and St Thomas' Hospital NHS Foundation Trust and King's College London, SE1 9RT, UK.

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http://dx.doi.org/10.1016/S0140-6736(07)60794-6DOI Listing
May 2007

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.

J Exp Med 2007 Feb 12;204(2):431-9. Epub 2007 Feb 12.

Center for Excellence in Vascular Biology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1084/jem.20060626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118716PMC
February 2007

Leptin as a proinflammatory cytokine.

Authors:
Graham M Lord

Contrib Nephrol 2006 ;151:151-164

Department of Nephrology and Transplantation, 5th Floor Thomas Guy House, King's College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1159/000095326DOI Listing
October 2006

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

Blood 2005 Nov 12;106(10):3432-9. Epub 2005 Jul 12.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1182/blood-2005-04-1393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895048PMC
November 2005

Recent developments in the transcriptional regulation of cytolytic effector cells.

Nat Rev Immunol 2004 Nov;4(11):900-11

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nri1490DOI Listing
November 2004

DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy.

Am J Kidney Dis 2004 Apr;43(4):e11-7

Division of Renal Medicine and Transplantation, Hammersmith Hospital NHS Trust, London, England UK.

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http://dx.doi.org/10.1053/j.ajkd.2003.11.024DOI Listing
April 2004

Leptin-deficient mice are protected from accelerated nephrotoxic nephritis.

Am J Pathol 2004 Feb;164(2):385-90

Department of Renal Medicine and Transplantation, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602275PMC
http://dx.doi.org/10.1016/S0002-9440(10)63128-8DOI Listing
February 2004

Role of leptin in immunology.

Authors:
Graham Lord

Nutr Rev 2002 Oct;60(10 Pt 2):S35-8; discussion S68-84, 85-7

Department of Immunology, Faculty of Medicine, Imperial College School of Science, Technology and Medicine, Hammersmith Hospital, London, England.

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http://dx.doi.org/10.1301/002966402320634913DOI Listing
October 2002

Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines.

J Leukoc Biol 2002 Aug;72(2):330-8

Department of Immunology, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom.

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August 2002

Balancing susceptibility to infection and autoimmunity: a role for leptin?

Trends Immunol 2002 Apr;23(4):182-7

Cattedra di Immunologia, Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli 'Federico II', Via S. Pansini 5, 80131, Napoli, Italy.

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http://dx.doi.org/10.1016/s1471-4906(02)02188-9DOI Listing
April 2002