Graham Leese

Graham Leese

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Graham Leese

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Increased mortality and morbidity in patients with chronic hypoparathyroidism: A population-based study.

Clin Endocrinol (Oxf) 2019 02 20;90(2):285-292. Epub 2018 Nov 20.

Department of Medicine, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1111/cen.13895DOI Listing
February 2019

Diabetes and pregnancy: national trends over a 15 year period.

Diabetologia 2018 05 11;61(5):1081-1088. Epub 2018 Jan 11.

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

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http://dx.doi.org/10.1007/s00125-017-4529-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448996PMC
May 2018

A Population-Based Study of the Epidemiology of Chronic Hypoparathyroidism.

J Bone Miner Res 2018 03 30;33(3):478-485. Epub 2017 Nov 30.

Department of Medicine, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1002/jbmr.3329DOI Listing
March 2018

Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea-induced hypoglycaemia: A GoDARTS Study.

Diabetes Obes Metab 2018 01 25;20(1):211-214. Epub 2017 Aug 25.

Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, Scotland, UK.

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http://dx.doi.org/10.1111/dom.13046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724509PMC
January 2018

Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity.

Clin Nutr 2017 12 25;36(6):1716-1719. Epub 2016 Nov 25.

Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Campus for Ageing and Vitality, Newcastle on Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1016/j.clnu.2016.11.012DOI Listing
December 2017

Morbidity and mortality in patients with hyperprolactinaemia: the PROLEARS study.

Endocr Connect 2017 Nov;6(8):580-588

Division of Molecular and Clinical MedicineSchool of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1530/EC-17-0171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633062PMC
November 2017

Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS).

Pharmacogenet Genomics 2017 Oct;27(10):356-362

aDivision of Molecular and Clinical Medicine, School of Medicine bCentre for Pharmacogenetics and Pharmacogenomics cMedicines Monitoring Unit (MEMO) and Hypertension Research Centre (HRC) dDepartment of Endocrinology and Diabetes, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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http://Insights.ovid.com/crossref?an=01213011-201710000-0000
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http://dx.doi.org/10.1097/FPC.0000000000000299DOI Listing
October 2017

Patients' attitudes and perceptions towards treatment of hypothyroidism in general practice: an in-depth qualitative interview study.

BJGP Open 2017 Jun 28;1(2):bjgpopen17X100977. Epub 2017 Jun 28.

Professor of General Practice and Primary Care, Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, UK.

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http://dx.doi.org/10.3399/bjgpopen17X100977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169953PMC
June 2017

The epidemiology of hyperprolactinaemia over 20 years in the Tayside region of Scotland: the Prolactin Epidemiology, Audit and Research Study (PROLEARS).

Clin Endocrinol (Oxf) 2017 Jan 7;86(1):60-67. Epub 2016 Sep 7.

Department of Endocrinology and Diabetes, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1111/cen.13156DOI Listing
January 2017

Liothyronine use in a 17 year observational population-based study - the tears study.

Clin Endocrinol (Oxf) 2016 Dec 21;85(6):918-925. Epub 2016 Mar 21.

Division of Cardiovascular & Diabetes Medicine, School Of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1111/cen.13052DOI Listing
December 2016

CYP2C8 and SLCO1B1 Variants and Therapeutic Response to Thiazolidinediones in Patients With Type 2 Diabetes.

Diabetes Care 2016 Nov 6;39(11):1902-1908. Epub 2016 Jun 6.

Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, Scotland

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http://dx.doi.org/10.2337/dc15-2464DOI Listing
November 2016

Association between retinal vasculature and muscle mass in older people.

Arch Gerontol Geriatr 2015 Nov-Dec;61(3):425-8. Epub 2015 Aug 4.

VAMPIRE-CVIP Group, School of Computing, University of Dundee, Dundee DD1 4HN, UK.

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http://dx.doi.org/10.1016/j.archger.2015.08.006DOI Listing
January 2016

When and how to audit a diabetic foot service.

Diabetes Metab Res Rev 2016 Jan;32 Suppl 1:311-7

Ward 5, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1002/dmrr.2749DOI Listing
January 2016

The Authors' Reply: Statins and thyroid-stimulating hormone.

Authors:
Graham Leese

Clin Endocrinol (Oxf) 2015 Nov 19;83(5):747-8. Epub 2015 Mar 19.

Medical Research Institute, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1111/cen.12757DOI Listing
November 2015

The risk of total mortality and cardiovascular mortality associated with impaired glucose regulation in Tayside, Scotland, UK: a record-linkage study in 214 094 people.

BMJ Open Diabetes Res Care 2015 16;3(1):e000102. Epub 2015 Sep 16.

Department of Diabetes and Endocrinology , Ninewells Hospital and Medical School , Dundee , UK.

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http://dx.doi.org/10.1136/bmjdrc-2015-000102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577610PMC
September 2015

Asymptomatic and mild primary hyperparathyroidism.

Ann Endocrinol (Paris) 2015 May 14;76(2):120-7. Epub 2015 Apr 14.

Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00034266150002
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http://dx.doi.org/10.1016/j.ando.2015.03.001DOI Listing
May 2015

Ethnicity and risk of cardiovascular disease (CVD): 4.8 year follow-up of patients with type 2 diabetes living in Scotland.

Diabetologia 2015 Apr 12;58(4):716-25. Epub 2015 Feb 12.

Institute of Cardiovascular and Medical Sciences, BHF Glasgow, Cardiovascular Research Centre, University of Glasgow, 126 University Place, G12 8TA, Glasgow, UK.

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http://link.springer.com/10.1007/s00125-015-3492-0
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http://dx.doi.org/10.1007/s00125-015-3492-0DOI Listing
April 2015

Progression from gestational diabetes to type 2 diabetes in one region of Scotland: an observational follow-up study.

BMC Pregnancy Childbirth 2015 Feb 3;15:11. Epub 2015 Feb 3.

School of Health Sciences, University of Stirling, Stirling, FK9 4LA, UK.

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http://dx.doi.org/10.1186/s12884-015-0457-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320450PMC
February 2015

Drugs that interact with levothyroxine: an observational study from the Thyroid Epidemiology, Audit and Research Study (TEARS).

Clin Endocrinol (Oxf) 2015 Jan 14;82(1):136-41. Epub 2014 Aug 14.

Department of Endocrinology, Ninewells Hospital, Dundee, UK.

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http://doi.wiley.com/10.1111/cen.12559
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http://dx.doi.org/10.1111/cen.12559DOI Listing
January 2015

The authors' reply: Nonsustained hypercalcaemia and primary hyperparathyroidism in the PEARS cohort.

Clin Endocrinol (Oxf) 2013 Dec 4;79(6):899-900. Epub 2013 Sep 4.

Dundee Epidemiology and Biostatistics Unit, Division of Population Health Sciences, University of Dundee, Dundee, Scotland.

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http://dx.doi.org/10.1111/cen.12308DOI Listing
December 2013

Subclinical and asymptomatic parathyroid disease: implications of emerging data.

Lancet Diabetes Endocrinol 2013 Dec 24;1(4):329-40. Epub 2013 Oct 24.

Medical Research Institute, Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, Dundee, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(13)70083-4DOI Listing
December 2013

What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS).

Clin Endocrinol (Oxf) 2013 Jul 19;79(1):27-34. Epub 2013 Apr 19.

Dundee Epidemiology and Biostatistics Unit, Division of Population Health Sciences, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1111/cen.12206DOI Listing
July 2013

Association between BMI measured within a year after diagnosis of type 2 diabetes and mortality.

Diabetes Care 2013 Apr 8;36(4):887-93. Epub 2012 Nov 8.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.2337/dc12-0944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609520PMC
April 2013

Thyroid testing in pregnant women with thyroid dysfunction in Tayside, Scotland: the thyroid epidemiology, audit and research study (TEARS).

Clin Endocrinol (Oxf) 2013 Mar;78(3):466-71

Dundee Epidemiology and Biostatistics Unit, Division of Population Health Science, Medical Research Institute, University of Dundee, Dundee, Scotland.

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http://dx.doi.org/10.1111/j.1365-2265.2012.04426.xDOI Listing
March 2013

Age- and gender-specific TSH reference intervals in people with no obvious thyroid disease in Tayside, Scotland: the Thyroid Epidemiology, Audit, and Research Study (TEARS).

J Clin Endocrinol Metab 2013 Mar 23;98(3):1147-53. Epub 2013 Jan 23.

Dundee Epidemiology and Biostatistics Unit, Division of Population Health Sciences, Medical Research Institute, MacKenzie Building, Kirsty Semple Way, University of Dundee, Dundee DD2 4BF, Scotland, United Kingdom.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2012-3191DOI Listing
March 2013

Should 'mild primary hyperparathyroidism' be reclassified as 'insidious': is it time to reconsider?

Clin Endocrinol (Oxf) 2011 Dec;75(6):730-7

University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2011.04201.xDOI Listing
December 2011

Mild primary hyperparathyroidism: a misnomer?

Expert Rev Endocrinol Metab 2011 Nov;6(6):747-749

b Ninewells Hospital and Medical School Dundee, DD1 9SY, Scotland, UK and University of Dundee, Dundee, Scotland, UK.

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http://dx.doi.org/10.1586/eem.11.67DOI Listing
November 2011

Clues to duration of undiagnosed disease from retinopathy and maculopathy at diagnosis in type 2 diabetes: a cross-sectional study.

Br J Ophthalmol 2011 Sep 22;95(9):1229-33. Epub 2010 Dec 22.

Department of Ophthalmology, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

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http://bjo.bmj.com/cgi/doi/10.1136/bjo.2010.196204
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http://dx.doi.org/10.1136/bjo.2010.196204DOI Listing
September 2011

A record linkage study of outcomes in patients with mild primary hyperparathyroidism: the Parathyroid Epidemiology and Audit Research Study (PEARS).

Clin Endocrinol (Oxf) 2011 Aug;75(2):169-76

Dundee Epidemiology and Biostatistics Unit, Division of Clinical and Population Sciences and Education, School of Medicine, University of Dundee, Dundee, UK.

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http://doi.wiley.com/10.1111/j.1365-2265.2010.03958.x
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http://dx.doi.org/10.1111/j.1365-2265.2010.03958.xDOI Listing
August 2011

The Thyroid Epidemiology, Audit, and Research Study (TEARS): morbidity in patients with endogenous subclinical hyperthyroidism.

J Clin Endocrinol Metab 2011 May 23;96(5):1344-51. Epub 2011 Feb 23.

Dundee Epidemiology and Biostatistics Unit, Division of Clinical and Population Sciences and Education, MacKenzie Building, Kirsty Semple Way, University of Dundee, Dundee, Scotland, DD2 4BF United Kingdom.

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http://dx.doi.org/10.1210/jc.2010-2693DOI Listing
May 2011

Levothyroxine dose and fractures in older adults.

BMJ 2011 Apr 28;342:d2250. Epub 2011 Apr 28.

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http://dx.doi.org/10.1136/bmj.d2250DOI Listing
April 2011

The Thyroid Epidemiology, Audit, and Research Study (TEARS): the natural history of endogenous subclinical hyperthyroidism.

J Clin Endocrinol Metab 2011 Jan 6;96(1):E1-8. Epub 2010 Oct 6.

Division of Clinical and Population Sciences and Education, University of Dundee, Dundee, Scotland, United Kingdom.

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http://dx.doi.org/10.1210/jc.2010-0854DOI Listing
January 2011

Increased mortality and morbidity in mild primary hyperparathyroid patients. The Parathyroid Epidemiology and Audit Research Study (PEARS).

Clin Endocrinol (Oxf) 2010 Jul 18;73(1):30-4. Epub 2009 Dec 18.

Dundee Epidemiology and Biostatistics Unit, Division of Clinical & Population Sciences & Education, University of Dundee, Scotland, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2009.03766.xDOI Listing
July 2010

The role of haemorrhage and exudate detection in automated grading of diabetic retinopathy.

Br J Ophthalmol 2010 Jun 5;94(6):706-11. Epub 2009 Aug 5.

Department of Bio-Medical Physics and Bio-Engineering, Aberdeen University and Grampian University Hospitals, Aberdeen, UK.

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http://bjo.bmj.com/content/94/6/706.full.pdf
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http://bjo.bmj.com/cgi/doi/10.1136/bjo.2008.149807
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http://dx.doi.org/10.1136/bjo.2008.149807DOI Listing
June 2010

Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy.

J Clin Endocrinol Metab 2010 Jan 11;95(1):186-93. Epub 2009 Nov 11.

Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom.

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http://dx.doi.org/10.1210/jc.2009-1625DOI Listing
January 2010

The role of modifiable pre-pregnancy risk factors in preventing adverse fetal outcomes among women with type 1 and type 2 diabetes.

Acta Obstet Gynecol Scand 2009 ;88(10):1153-7

Division of Community Health Sciences, University of Dundee, MacKenzie Building, Kirsty Semple Way, Dundee, DD2 4BF, UK.

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http://dx.doi.org/10.1080/00016340903176859DOI Listing
December 2009

Epidemiology of primary hyperparathyroidism in Tayside, Scotland, UK.

Clin Endocrinol (Oxf) 2009 Oct;71(4):485-93

Dundee Epidemiology and Biostatistics Unit, Division of Clinical and Population Sciences and Education, University of Dundee, Kirsty Semple Way, Dundee, Scotland, UK.

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http://doi.wiley.com/10.1111/j.1365-2265.2008.03520.x
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http://dx.doi.org/10.1111/j.1365-2265.2008.03520.xDOI Listing
October 2009

Intraoperative optical identification of pituitary adenomas.

J Neurooncol 2009 May 9;92(3):417-21. Epub 2009 Apr 9.

Department of Neurosurgery, Ninewells Hospital and Medical School, Dundee, DD1 9SY, Scotland, UK.

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http://link.springer.com/content/pdf/10.1007/s11060-009-9820
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http://link.springer.com/10.1007/s11060-009-9820-9
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http://dx.doi.org/10.1007/s11060-009-9820-9DOI Listing
May 2009

Lymphocytic hypophysitis occurring simultaneously with a functioning pituitary adenoma.

Endocr J 2008 Aug 23;55(4):729-35. Epub 2008 May 23.

Department of Diabetes, School of Clinical Sciences, University Hospital Aintree, Liverpool, England.

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http://pathology.jhu.edu/hypophysitis/pdf/584_2008_Cuthberst
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http://dx.doi.org/10.1507/endocrj.k08e-043DOI Listing
August 2008

Diabetic retinopathy: more patients, less laser: a longitudinal population-based study in Tayside, Scotland.

Diabetes Care 2008 Jun 17;31(6):1126-31. Epub 2008 Mar 17.

Department of Ophthalmology, Ninewells Hospital and Medical School, Dundee, UK.

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http://dx.doi.org/10.2337/dc07-1498DOI Listing
June 2008

Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus: systematic review of observational studies.

BMC Pregnancy Childbirth 2006 Oct 30;6:30. Epub 2006 Oct 30.

Division of Community Health Sciences, University of Dundee, MacKenzie Building, Kirsty Semple Way, Dundee, UK, DD2 4BF.

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http://dx.doi.org/10.1186/1471-2393-6-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635059PMC
October 2006

Osteoporosis assessment and treatment in older patients who have sustained a hip fracture.

Scott Med J 2006 May;51(2):32-5

Section of Ageing and Health, Department of Medicine, Ninewells Hospital, Dundee DD1 9SY.

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http://journals.sagepub.com/doi/10.1258/RSMSMJ.51.2.32
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http://dx.doi.org/10.1258/RSMSMJ.51.2.32DOI Listing
May 2006

Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS study.

Nucl Recept 2005 Nov 25;3. Epub 2005 Nov 25.

The Institute of Cardiovascular Research, Ninewells Hospital and Medical School, Dundee, DD1 9SY, Scotland, UK.

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http://dx.doi.org/10.1186/1478-1336-3-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1318486PMC
November 2005

Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study.

Circulation 2005 Jun 31;111(22):2927-34. Epub 2005 May 31.

Institute for Cardiovascular Research, Biomedical Research Centre, Ninewells Hospital and Medical School, Dundee, Scotland.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.104.5
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http://dx.doi.org/10.1161/CIRCULATIONAHA.104.509224DOI Listing
June 2005

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle.

FASEB J 2005 Mar 13;19(3):422-4. Epub 2004 Dec 13.

Division of Molecular Physiology, School of Life Sciences, University of Dundee, Dundee, Scotland.

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http://dx.doi.org/10.1096/fj.04-2640fjeDOI Listing
March 2005

Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.

Arterioscler Thromb Vasc Biol 2004 Dec 14;24(12):2403-7. Epub 2004 Oct 14.

Institute for Cardiovascular Research, Biomedical Research Centre, Ninewells Hospital and Medical School, Dundee, Scotland.

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http://dx.doi.org/10.1161/01.ATV.0000147897.57527.e4DOI Listing
December 2004