Graham Bignell

Graham Bignell

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Graham Bignell

Graham Bignell

Publications by authors named "Graham Bignell"

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The germline genetic component of drug sensitivity in cancer cell lines.

Nat Commun 2018 08 23;9(1):3385. Epub 2018 Aug 23.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

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http://www.nature.com/articles/s41467-018-05811-3
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http://dx.doi.org/10.1038/s41467-018-05811-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107640PMC
August 2018

Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer.

Cancer Res 2018 02 11;78(3):769-780. Epub 2017 Dec 11.

European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522379PMC
February 2018

The relative timing of mutations in a breast cancer genome.

PLoS One 2013 10;8(6):e64991. Epub 2013 Jun 10.

Hutchison/MRC Research Centre and Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064991PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677865PMC
February 2014

Signatures of mutational processes in human cancer.

Nature 2013 Aug 14;500(7463):415-21. Epub 2013 Aug 14.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776390PMC
August 2013

PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data.

Biostatistics 2010 Jan 15;11(1):164-75. Epub 2009 Oct 15.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1093/biostatistics/kxp045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800165PMC
January 2010

CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data.

Bioinformatics 2005 Aug 19;21(15):3308-11. Epub 2005 May 19.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/bti500DOI Listing
August 2005

A survey of homozygous deletions in human cancer genomes.

Proc Natl Acad Sci U S A 2005 Mar 10;102(12):4542-7. Epub 2005 Mar 10.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK.

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http://dx.doi.org/10.1073/pnas.0408593102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC555487PMC
March 2005