Graeme J Stewart

Graeme J Stewart

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Graeme J Stewart

Graeme J Stewart

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The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis.

Sci Rep 2020 Jan 13;10(1):193. Epub 2020 Jan 13.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1038/s41598-019-55850-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957475PMC
January 2020

Amyloid Cardiomyopathy.

Heart Lung Circ 2019 Dec 17. Epub 2019 Dec 17.

Cardiology Department, St. Vincent's Hospital, Sydney NSW, Australia; Molecular Cardiology Division, Victor Chang Cardiac Research Institute, Sydney NSW, Australia; St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2019.11.019DOI Listing
December 2019

Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein-Barr Virus hypomethylated regions.

Genes Immun 2019 Oct 16. Epub 2019 Oct 16.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, The University of Sydney, 176 Hawkesbury Rd, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1038/s41435-019-0089-5DOI Listing
October 2019

Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression.

Mult Scler J Exp Transl Clin 2016 Jan-Dec;2:2055217316637087. Epub 2016 Mar 11.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Australia.

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http://dx.doi.org/10.1177/2055217316637087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433329PMC
March 2016

The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies.

Clin Immunol 2016 Feb 4;163:96-107. Epub 2016 Jan 4.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales 2145, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.12.015DOI Listing
February 2016

IFNL3 mediates interaction between innate immune cells: Implications for hepatitis C virus pathogenesis.

Innate Immun 2014 Aug 17;20(6):598-605. Epub 2013 Sep 17.

Institute for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1177/1753425913503385DOI Listing
August 2014

IL7Rα expression and upregulation by IFNβ in dendritic cell subsets is haplotype-dependent.

PLoS One 2013 16;8(10):e77508. Epub 2013 Oct 16.

Institute for Immunology and Allergy Research, Westmead Millennium Institute, Sydney, New South Whales, Australia ; Department of Medicine, University of Sydney, Sydney, New South Whales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077508PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797747PMC
August 2014

The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease.

Clin Immunol 2014 Mar 15;151(1):16-24. Epub 2014 Jan 15.

Institute for Immunology and Allergy Research, Westmead Millennium Institute University of Sydney, Sydney, New South Wales 2145, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.01.003DOI Listing
March 2014

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

Ann Neurol 2011 Dec;70(6):897-912

Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://doi.wiley.com/10.1002/ana.22609
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http://dx.doi.org/10.1002/ana.22609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247076PMC
December 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL and TRAIL double-deficient mice.

Blood 2010 Apr 25;115(16):3258-68. Epub 2010 Feb 25.

Institute for Biotechnology of Infectious Disease, and Department of Medical and Molecular Biosciences, University of Technology, Sydney.

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http://dx.doi.org/10.1182/blood-2009-11-255497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858490PMC
April 2010

Implementation of the Garling recommendations can offer real hope for rescuing the New South Wales public hospital system.

Med J Aust 2009 Jan;190(2):80-2

NSW Medical Staff Executive Council, Sydney, NSW, Australia.

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January 2009

Tolerance induction in a large-animal model using total lymphoid irradiation and intrathymic bone marrow.

Transplantation 2008 Dec;86(12):1830-6

Division of Solid Organ Transplantation, University of Rochester Medical Center, Rochester, NY, USA.

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https://insights.ovid.com/crossref?an=00007890-200812270-000
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http://dx.doi.org/10.1097/TP.0b013e3181910e67DOI Listing
December 2008

BAFF is a biological response marker to IFN-beta treatment in multiple sclerosis.

J Interferon Cytokine Res 2008 Sep;28(9):529-39

Westmead Millennium Institute, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1089/jir.2008.0007DOI Listing
September 2008

CD127 immunophenotyping suggests altered CD4+ T cell regulation in primary progressive multiple sclerosis.

J Autoimmun 2008 Aug 11;31(1):52-8. Epub 2008 Apr 11.

Department of Immunology, Westmead Millennium Institute, University of Sydney, Darcy Road, Westmead 2145, Australia.

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http://dx.doi.org/10.1016/j.jaut.2008.02.003DOI Listing
August 2008

Functional characterization of the atopy-associated gene PHF11.

J Allergy Clin Immunol 2008 May 11;121(5):1148-1154.e3. Epub 2008 Apr 11.

Institute for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Westmead, Australia.

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http://dx.doi.org/10.1016/j.jaci.2008.02.028DOI Listing
May 2008

Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis.

Int Arch Allergy Immunol 2006 29;141(4):331-6. Epub 2006 Aug 29.

Institute for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Westmead, Australia.

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https://www.karger.com/Article/FullText/95459
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http://dx.doi.org/10.1159/000095459DOI Listing
December 2006

An investigation of NOS2A promoter polymorphisms in Australian multiple sclerosis patients.

Eur J Hum Genet 2005 Jul;13(7):815-22

The Institute for Immunology and Allergy Research, Westmead Millennium Institute, Westmead Campus, University of Sydney, Westmead NSW 2145, Australia.

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http://dx.doi.org/10.1038/sj.ejhg.5201422DOI Listing
July 2005

HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion.

AIDS Res Hum Retroviruses 2004 May;20(5):547-55

Institute for Immunology and Allergy Research, Westmead Millennium Institute, NSW 2145, Australia.

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http://www.liebertpub.com/doi/10.1089/088922204323087804
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http://dx.doi.org/10.1089/088922204323087804DOI Listing
May 2004

Analysis of the CCL3-L1 gene for association with HIV-1 susceptibility and disease progression.

AIDS 2004 Apr;18(7):1069-71

Institute for Immunology and Allergy Research, Westmead Millennium Institute, Westmead Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1097/00002030-200404300-00017DOI Listing
April 2004

Association of common T cell activation gene polymorphisms with multiple sclerosis in Australian patients.

J Neuroimmunol 2004 Mar;148(1-2):218-30

Institute for Immunology and Allergy Research (Westmead Millennium Institute), Level 2 ICPMR, University of Sydney, Westmead Hospital, Westmead, NSW 2145, Australia.

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http://dx.doi.org/10.1016/j.jneuroim.2003.12.003DOI Listing
March 2004

Effector HIV-specific cytotoxic T-lymphocyte activity in long-term nonprogressors: associations with viral replication and progression.

J Med Virol 2003 Dec;71(4):483-91

Department of Immunology and Infectious Diseases, Sydney Children's Hospital, Randwick, Australia.

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http://dx.doi.org/10.1002/jmv.10525DOI Listing
December 2003

Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis.

Eur J Hum Genet 2003 Jul;11(7):509-15

Institute for Immunology and Allergy Research (Westmead Millennium Institute), Westmead Hospital, Westmead, NSW 2145, Australia.

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http://dx.doi.org/10.1038/sj.ejhg.5200994DOI Listing
July 2003