Grace Parraga

Grace Parraga

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Grace Parraga

Grace Parraga

Publications by authors named "Grace Parraga"

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Accelerated Xe MRI morphometry of terminal airspace enlargement: Feasibility in volunteers and those with alpha-1 antitrypsin deficiency.

Magn Reson Med 2020 Jul 25;84(1):416-426. Epub 2019 Nov 25.

Division of Respirology, Department of Medicine, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/mrm.28091DOI Listing
July 2020

Pulmonary Imaging Phenotypes of Chronic Obstructive Pulmonary Disease Using Multiparametric Response Maps.

Radiology 2020 Apr 25;295(1):227-236. Epub 2020 Feb 25.

From the Robarts Research Institute (J.L.M., A.R.W., R.L.E., A.L.B., G.P.), School of Biomedical Engineering (J.L.M., G.P.), Department of Medical Biophysics (A.R.W., R.L.E., A.L.B., G.P.), and Division of Respirology, Department of Medicine (D.G.M., G.P.), Western University, 1151 Richmond St N, London, ON, Canada N6A 5B7; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, Calif (D.P.I.C.); and Department of Physics, Ryerson University, Toronto, Ontario, Canada (M.K.).

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http://dx.doi.org/10.1148/radiol.2020191735DOI Listing
April 2020

FEV and MRI ventilation defect reversibility in asthma and COPD.

Eur Respir J 2020 Mar 26;55(3). Epub 2020 Mar 26.

Robarts Research Institute, Western University, London, ON, Canada

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http://dx.doi.org/10.1183/13993003.01947-2019DOI Listing
March 2020

Pulmonary xenon-129 MRI: new opportunities to unravel enigmas in respiratory medicine.

Eur Respir J 2020 Feb 6;55(2). Epub 2020 Feb 6.

Robarts Research Institute, London, ON, Canada

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http://dx.doi.org/10.1183/13993003.01987-2019DOI Listing
February 2020

Is Computed Tomography Airway Count Related to Asthma Severity and Airway Structure-function?

Am J Respir Crit Care Med 2020 Jan 2. Epub 2020 Jan 2.

Robarts Research Institute, 113611, London, Ontario, Canada.

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http://dx.doi.org/10.1164/rccm.201908-1552OCDOI Listing
January 2020

Visualization of the Small Airways:What It Is and Why It Matters.

Radiology 2019 12 15;293(3):674-675. Epub 2019 Oct 15.

From the Department of Radiology, Professor of Cardiothoracic Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792-3252 (M.L.S.); and Department of Medical Biophysics and Robarts Research Institute, Western University, London, Canada (G.P.).

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http://dx.doi.org/10.1148/radiol.2019192025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884066PMC
December 2019

Chronic Obstructive Pulmonary Disease: Thoracic CT Texture Analysis and Machine Learning to Predict Pulmonary Ventilation.

Radiology 2019 12 22;293(3):676-684. Epub 2019 Oct 22.

From the Robarts Research Institute, London, Canada (A.W., A.F., G.P.); Department of Medical Biophysics (A.W., A.D.W., A.F., G.P.), Division of Respirology, Department of Medicine (D.G.M., G.P.), and Department of Oncology (A.D.W.), Western University, 1151 Richmond St N, London, ON, Canada N6A 5B7; and Department of Radiation Oncology, Stanford University School of Medicine, Stanford, Calif (D.P.I.C.).

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http://dx.doi.org/10.1148/radiol.2019190450DOI Listing
December 2019

Nonidentical Twins With Asthma: Spatially Matched CT Airway and MRI Ventilation Abnormalities.

Chest 2019 Dec;156(6):e111-e116

Robarts Research Institute, Western University, London; Department of Medical Biophysics, Western University, London; Division of Respirology, Department of Medicine, Western University, London, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.08.004DOI Listing
December 2019

Normalisation of MRI ventilation heterogeneity in severe asthma by dupilumab.

Thorax 2019 Nov 8;74(11):1087-1088. Epub 2019 Jul 8.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada

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http://dx.doi.org/10.1136/thoraxjnl-2019-213415DOI Listing
November 2019

Hyperpolarized Helium 3 MRI in Mild-to-Moderate Asthma: Prediction of Postbronchodilator Reversibility.

Radiology 2019 10 6;293(1):212-220. Epub 2019 Aug 6.

From the Robarts Research Institute (R.L.E., G.P.), Department of Medical Biophysics (R.L.E., G.P.), and Division of Respirology, Department of Medicine (C.L., D.G.M., G.P.), Western University, 1151 Richmond St N, London, ON, Canada N6A 5B7; and Department of Medicine, McMaster University, Hamilton, Canada (S.S.).

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http://dx.doi.org/10.1148/radiol.2019190420DOI Listing
October 2019

Advanced pulmonary MRI to quantify alveolar and acinar duct abnormalities: Current status and future clinical applications.

J Magn Reson Imaging 2019 07 13;50(1):28-40. Epub 2019 Jan 13.

Department of Physics and Astronomy, University of Western Ontario, London, Canada.

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http://doi.wiley.com/10.1002/jmri.26623
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http://dx.doi.org/10.1002/jmri.26623DOI Listing
July 2019

MRI and CT lung biomarkers: Towards an in vivo understanding of lung biomechanics.

Clin Biomech (Bristol, Avon) 2019 06 29;66:107-122. Epub 2017 Sep 29.

Robarts Research Institute, Western University, London, Canada; Department of Medical Biophysics, Western University, London, Canada; Graduate Program in Biomedical Engineering, Western University, London, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiomech.2017.09.016DOI Listing
June 2019

Rapid single-breath hyperpolarized noble gas MRI-based biomarkers of airspace enlargement.

J Magn Reson Imaging 2019 Jun 21;49(6):1713-1722. Epub 2018 Dec 21.

Robarts Research Institute, University of Western Ontario, London, Canada.

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http://doi.wiley.com/10.1002/jmri.26574
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http://dx.doi.org/10.1002/jmri.26574DOI Listing
June 2019

CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma.

Chest 2019 06 23;155(6):1178-1189. Epub 2019 Mar 23.

Department of Medicine, McMaster University, Hamilton, ON, Canada; Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.chest.2019.02.403DOI Listing
June 2019

A framework for Fourier-decomposition free-breathing pulmonary H MRI ventilation measurements.

Magn Reson Med 2019 03 26;81(3):2135-2146. Epub 2018 Oct 26.

Robarts Research Institute, Western University, London, Ontario, Canada.

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http://doi.wiley.com/10.1002/mrm.27527
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http://dx.doi.org/10.1002/mrm.27527DOI Listing
March 2019

Hyperpolarized He MRI ventilatory apparent diffusion coefficient of alpha-1 antitrypsin deficiency.

J Magn Reson Imaging 2019 01 13;49(1):311-313. Epub 2018 Aug 13.

Robarts Research Institute, Western University, London, ON, Canada.

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http://dx.doi.org/10.1002/jmri.26202DOI Listing
January 2019

Oscillometry and pulmonary magnetic resonance imaging in asthma and COPD.

Physiol Rep 2019 01;7(1):e13955

CIUSSS de l'Ouest-de-l'Île-de-Montréal, Montreal Chest Institute, Meakins-Christie Laboratories, Oscillometry Unit and Centre for Innovative Medicine, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.14814/phy2.13955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328923PMC
January 2019

COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging.

Eur Respir J 2018 11 29;52(5). Epub 2018 Nov 29.

Robarts Research Institute, Western University, London, ON, Canada.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01570
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http://dx.doi.org/10.1183/13993003.01570-2018DOI Listing
November 2018

Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

September 2018

Oscillometry and pulmonary MRI measurements of ventilation heterogeneity in obstructive lung disease: relationship to quality of life and disease control.

J Appl Physiol (1985) 2018 07 15;125(1):73-85. Epub 2018 Mar 15.

Robarts Research Institute, Western University , London, Ontario , Canada.

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http://dx.doi.org/10.1152/japplphysiol.01031.2017DOI Listing
July 2018

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

PLoS One 2018 12;13(4):e0191172. Epub 2018 Apr 12.

Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191172PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896895PMC
July 2018

What is the minimal clinically important difference for helium-3 magnetic resonance imaging ventilation defects?

Eur Respir J 2018 06 28;51(6). Epub 2018 Jun 28.

Robarts Research Institute, Western University, London, ON, Canada.

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http://dx.doi.org/10.1183/13993003.00324-2018DOI Listing
June 2018

Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation.

Radiology 2018 05 22;287(2):693-704. Epub 2018 Feb 22.

From the Robarts Research Institute (D.P.I.C., R.L.E., S.S., F.G., J.S.H.B., A.J.M., G.P.), Department of Medical Biophysics (D.P.I.C., R.L.E., G.P.), Graduate Program in Biomedical Engineering (F.G., J.S.H.B., A.J.M.), and Department of Medicine, Division of Respirology (D.G.M.), Western University, University of Western Ontario, 1151 Richmond St N, London, ON, Canada N6A 5B7; and Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada (S.S., P.N., G.P.).

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http://dx.doi.org/10.1148/radiol.2018171993DOI Listing
May 2018

Development of a pulmonary imaging biomarker pipeline for phenotyping of chronic lung disease.

J Med Imaging (Bellingham) 2018 Apr 28;5(2):026002. Epub 2018 Jun 28.

University of Western Ontario, Robarts Research Institute, London, Ontario, Canada.

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http://dx.doi.org/10.1117/1.JMI.5.2.026002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022861PMC
April 2018

On the Potential Role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction.

Acad Radiol 2018 02 16;25(2):159-168. Epub 2017 Oct 16.

Robarts Research Institute, Western University, 1151 Richmond Street N, London, ON N6A 5B7, Canada; Department of Medical Biophysics, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2017.08.010DOI Listing
February 2018

Pulmonary MRI morphometry modeling of airspace enlargement in chronic obstructive pulmonary disease and alpha-1 antitrypsin deficiency.

Magn Reson Med 2018 Jan 15;79(1):439-448. Epub 2017 Feb 15.

Robarts Research Institute, London, Canada.

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http://dx.doi.org/10.1002/mrm.26642DOI Listing
January 2018

Through the Looking Glass and What Was Found There: Imaging Biomarkers of Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2017 12;196(11):1364-1366

1 Robarts Research Institute and.

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http://dx.doi.org/10.1164/rccm.201707-1473EDDOI Listing
December 2017

Pulmonary He Magnetic Resonance Imaging Biomarkers of Regional Airspace Enlargement in Alpha-1 Antitrypsin Deficiency.

Acad Radiol 2017 11 20;24(11):1402-1411. Epub 2017 Jun 20.

Robarts Research Institute, 1151 Richmond Street North, London, ON, Canada N6A 5B7; Department of Medical Biophysics, The University of Western Ontario, 1151 Richmond St North, London, ON, Canada N6A 5C1. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10766332173022
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http://dx.doi.org/10.1016/j.acra.2017.05.008DOI Listing
November 2017

Free-breathing Functional Pulmonary MRI: Response to Bronchodilator and Bronchoprovocation in Severe Asthma.

Acad Radiol 2017 10 24;24(10):1268-1276. Epub 2017 May 24.

Robarts Research Institute, The University of Western Ontario, London, Canada; Department of Medical Biophysics, The University of Western Ontario, London, Canada; Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2017.04.012DOI Listing
October 2017

Sensitive three-dimensional ultrasound assessment of carotid atherosclerosis by weighted average of local vessel wall and plaque thickness change.

Med Phys 2017 Oct 31;44(10):5280-5292. Epub 2017 Aug 31.

Department of Electronic Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong.

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http://dx.doi.org/10.1002/mp.12507DOI Listing
October 2017

Mild chronic obstructive pulmonary disease: why spirometry is not sufficient!

Expert Rev Respir Med 2017 07 5;11(7):549-563. Epub 2017 Jun 5.

a Department of Medicine , Queen's University and Kingston General Hospital , Kingston , ON , Canada.

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http://dx.doi.org/10.1080/17476348.2017.1334553DOI Listing
July 2017

Thoracic CT-MRI coregistration for regional pulmonary structure-function measurements of obstructive lung disease.

Med Phys 2017 May 11;44(5):1718-1733. Epub 2017 Apr 11.

Robarts Research Institute, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/mp.12160DOI Listing
May 2017

Ultrashort echo time MRI biomarkers of asthma.

J Magn Reson Imaging 2017 04 12;45(4):1204-1215. Epub 2016 Oct 12.

Robarts Research Institute, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/jmri.25503DOI Listing
April 2017

A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis.

Eur Respir J 2017 03 15;49(3). Epub 2017 Mar 15.

Dept of Medicine, McMaster University and St Joseph's Healthcare, Hamilton, ON, Canada

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http://dx.doi.org/10.1183/13993003.02486-2016DOI Listing
March 2017

Pulmonary Artery Abnormalities in Ex-smokers with and without Airflow Obstruction.

COPD 2016 25;13(2):224-34. Epub 2015 Nov 25.

a 1 Robarts Research Institute , London , Ontario , Canada.

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http://dx.doi.org/10.3109/15412555.2015.1074666DOI Listing
January 2017

Management of COPD: Is there a role for quantitative imaging?

Eur J Radiol 2017 Jan 28;86:335-342. Epub 2016 Aug 28.

Robarts Research Institute, The University of Western Ontario, London, Canada; Department of Medical Biophysics, The University of Western Ontario, London, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2016.08.022DOI Listing
January 2017

Why Is Your Patient Still Short of Breath? Understanding the Complex Pathophysiology of Dyspnea in Chronic Kidney Disease.

Semin Dial 2017 01 28;30(1):50-57. Epub 2016 Sep 28.

Department of Medicine and Medical Biophysics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada.

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http://doi.wiley.com/10.1111/sdi.12548
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http://dx.doi.org/10.1111/sdi.12548DOI Listing
January 2017

Noncystic Fibrosis Bronchiectasis: Regional Abnormalities and Response to Airway Clearance Therapy Using Pulmonary Functional Magnetic Resonance Imaging.

Acad Radiol 2017 01 4;24(1):4-12. Epub 2016 Oct 4.

Robarts Research Institute, The University of Western Ontario, London, Canada; Department of Medical Biophysics, The University of Western Ontario, London, Canada; Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2016.08.021DOI Listing
January 2017

Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease.

COPD 2016 2;13(1):66-74. Epub 2015 Oct 2.

a Imaging Research Laboratories, Robarts Research Institute , The University of Western Ontario , London , Canada.

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http://dx.doi.org/10.3109/15412555.2015.1043523DOI Listing
October 2016

Three-dimensional ultrasound measurements of carotid vessel wall and plaque thickness and their relationship with pulmonary abnormalities in ex-smokers without airflow limitation.

Int J Cardiovasc Imaging 2016 Sep 24;32(9):1391-1402. Epub 2016 Jun 24.

Department of Electronic Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong.

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http://dx.doi.org/10.1007/s10554-016-0931-zDOI Listing
September 2016

Carotid Artery Atherosclerosis in Patients with Active Rheumatoid Arthritis: Predictors of Plaque Occurrence and Progression Over 24 Weeks.

Open Rheumatol J 2016 30;10:49-59. Epub 2016 Sep 30.

Schulich School of Medicine & Dentistry, Western University, Robarts Research Institute,1151 Richmond St. N., London, Ontario, N6A 5B7, Canada.

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http://benthamopen.com/ABSTRACT/TORJ-10-49
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http://dx.doi.org/10.2174/1874312901610010049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093864PMC
September 2016

Is ventilation heterogeneity related to asthma control?

Eur Respir J 2016 08 12;48(2):370-9. Epub 2016 May 12.

Robarts Research Institute, The University of Western Ontario, London, ON, Canada Graduate Program in Biomedical Engineering, The University of Western Ontario, London, ON, Canada

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http://dx.doi.org/10.1183/13993003.00393-2016DOI Listing
August 2016

Early stage radiation-induced lung injury detected using hyperpolarized (129) Xe Morphometry: Proof-of-concept demonstration in a rat model.

Magn Reson Med 2016 06 8;75(6):2421-31. Epub 2015 Jul 8.

Imaging Research Laboratories, Robarts Research Institute, Western University, London, Ontario, Canada.

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http://doi.wiley.com/10.1002/mrm.25825
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http://dx.doi.org/10.1002/mrm.25825DOI Listing
June 2016

Pulmonary Imaging Biomarkers of Gas Trapping and Emphysema in COPD: (3)He MR Imaging and CT Parametric Response Maps.

Radiology 2016 May 8;279(2):597-608. Epub 2016 Jan 8.

From the Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond St N, London, ON, Canada N6A 5B7 (D.P.I.C., N.Z., F.G., D.P., G.P.); Department of Medical Biophysics (D.P.I.C., D.P., G.P.), Graduate Program in Biomedical Engineering (F.G., G.P.), and Division of Respirology, Department of Medicine (D.G.M.), The University of Western Ontario, London, Ont, Canada; and Heart and Lung Institute, St Paul's Hospital, Vancouver, BC, Canada (M.K.).

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http://dx.doi.org/10.1148/radiol.2015151484DOI Listing
May 2016

Ventilation Heterogeneity in Never-smokers and COPD:: Comparison of Pulmonary Functional Magnetic Resonance Imaging with the Poorly Communicating Fraction Derived From Plethysmography.

Acad Radiol 2016 Apr 8;23(4):398-405. Epub 2016 Jan 8.

Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond Street North, London, N6A 5B7, Canada; Department of Medical Biophysics, The University of Western Ontario, 1151 Richmond St North, London, N6A 5B7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2015.10.022DOI Listing
April 2016

Magnetic resonance imaging biomarkers of chronic obstructive pulmonary disease prior to radiation therapy for non-small cell lung cancer.

Eur J Radiol Open 2015 26;2:81-9. Epub 2015 May 26.

Imaging Research Laboratories, Robarts Research Institute, London, Canada; Department of Medical Biophysics, The University of Western Ontario, London, Canada; Department of Oncology, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1016/j.ejro.2015.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750562PMC
March 2016

Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes.

J Magn Reson Imaging 2016 Mar 22;43(3):544-57. Epub 2015 Jul 22.

Robarts Research Institute, University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/jmri.25010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207206PMC
March 2016

Imaging Biomarkers in Lymphangioleiomyomatosis Clinical Trials. A Wolf in Sheep's Clothing?

Ann Am Thorac Soc 2016 Mar;13(3):307-8

2 Robarts Research Institute, Imaging Research Laboratories, London, Ontario, Canada; and.

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http://dx.doi.org/10.1513/AnnalsATS.201512-818EDDOI Listing
March 2016

Imaging how and where we breathe oxygen: another Big Short?

J Thorac Dis 2016 Mar;8(3):E204-7

1 Robarts Research Institute, 2 Department of Medical Biophysics, 3 Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.21037/jtd.2016.01.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805788PMC
March 2016

This is what COPD looks like.

Respirology 2016 Feb 26;21(2):224-36. Epub 2015 Aug 26.

Robarts Research Institute, London, Canada.

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http://dx.doi.org/10.1111/resp.12611DOI Listing
February 2016

Second-order Texture Measurements of (3)He Ventilation MRI: Proof-of-concept Evaluation of Asthma Bronchodilator Response.

Acad Radiol 2016 Feb 18;23(2):176-85. Epub 2015 Nov 18.

Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond Street North, London, ON N6A 5B7, Canada; Department of Medical Biophysics, The University of Western Ontario, London, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2015.10.010DOI Listing
February 2016

Three-Dimensional Ultrasound of Carotid Plaque.

Neuroimaging Clin N Am 2016 Feb;26(1):69-80

Imaging Research Laboratories, Department of Medical Biophysics, Robarts Research Institute, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.nic.2015.09.006DOI Listing
February 2016

COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity?

Radiology 2015 Dec 7;277(3):872-80. Epub 2015 Jul 7.

From the James Hogg Research Centre, the University of British Columbia and the Institute of Heart and Lung Health, St Paul's Hospital, Vancouver, BC, Canada (M.K., D.D.S., H.O.C.); Imaging Research Laboratories, Robarts Research Institute (D.P., G.P.), and Department of Medical Biophysics (D.P., G.P.) and Division of Respirology, Department of Medicine (D.G.M.), the University of Western Ontario, 1151 Richmond St N, London, ON, Canada N6A 5B7.

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http://dx.doi.org/10.1148/radiol.2015150037DOI Listing
December 2015

Noninvasive quantification of alveolar morphometry in elderly never- and ex-smokers.

Physiol Rep 2015 Oct;3(10)

Imaging Research Laboratories, Robarts Research Institute The University of Western Ontario, London, Ontario, Canada Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada

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http://dx.doi.org/10.14814/phy2.12583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632953PMC
October 2015

Ventilation heterogeneity in ex-smokers without airflow limitation.

Acad Radiol 2015 Aug 23;22(8):1068-78. Epub 2015 May 23.

Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond St N, London, ON, Canada N6A 5B7; Department of Medical Biophysics, The University of Western Ontario, London, Canada; Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2015.04.006DOI Listing
August 2015

Globally optimal co-segmentation of three-dimensional pulmonary ¹H and hyperpolarized ³He MRI with spatial consistence prior.

Med Image Anal 2015 Jul 17;23(1):43-55. Epub 2015 Apr 17.

Robarts Research Institute, The University of Western Ontario, London, ON, Canada; Graduate Program in Biomedical Engineering, The University of Western Ontario, London, ON, Canada; Department of Medical Biophysics, The University of Western Ontario, London, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.media.2015.04.001DOI Listing
July 2015

Differences in hyperpolarized (3) He ventilation imaging after 4 years in adults with cystic fibrosis.

J Magn Reson Imaging 2015 Jun 30;41(6):1701-7. Epub 2014 Aug 30.

Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/jmri.24744DOI Listing
June 2015

Ultra-short echo-time pulmonary MRI: evaluation and reproducibility in COPD subjects with and without bronchiectasis.

J Magn Reson Imaging 2015 May 26;41(5):1465-74. Epub 2014 Jun 26.

Imaging Research Laboratories, Robarts Research Institute, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/jmri.24680DOI Listing
May 2015

Free-breathing pulmonary 1H and Hyperpolarized 3He MRI: comparison in COPD and bronchiectasis.

Acad Radiol 2015 Mar 6;22(3):320-9. Epub 2014 Dec 6.

Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond Street North, London, Ontario, Canada N6A 5B7; Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada; Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Ontario, Canada; Department of Medical Imaging, The University of Western Ontario, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2014.10.003DOI Listing
March 2015

Pulmonary abnormalities and carotid atherosclerosis in ex-smokers without airflow limitation.

COPD 2015 Feb 12;12(1):62-70. Epub 2014 Jun 12.

1Imaging Research Laboratories, Robarts Research Institute, Department of Medical Biophysics, The University of Western Ontario , London, Ontario , Canada.

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http://dx.doi.org/10.3109/15412555.2014.908833DOI Listing
February 2015

Pulmonary imaging abnormalities in an adult case of congenital lobar emphysema.

J Radiol Case Rep 2015 Feb 28;9(2):9-15. Epub 2015 Feb 28.

Imaging Research Laboratories, Robarts Research Institute, The University of Western Ontario, London, Canada ; Department of Medical Biophysics, The University of Western Ontario, London, Canada ; Department of Medical Imaging, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.3941/jrcr.v9i2.2048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391802PMC
February 2015

Hyperpolarized (3)He ventilation defects used to predict pulmonary exacerbations in mild to moderate chronic obstructive pulmonary disease.

Radiology 2014 Dec 24;273(3):887-96. Epub 2014 Jun 24.

From the Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond St, London, ON, Canada N6A 5B7 (M.K., D.P., G.P.); Department of Medical Biophysics (M.K., D.P., G.P.) and Division of Respirology, Department of Medicine (D.G.M.), University of Western Ontario, London, Ont, Canada; and Department of Radiology and James Hogg Research Centre, University of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada (H.O.C.).

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http://dx.doi.org/10.1148/radiol.14140161DOI Listing
December 2014

Paradoxical response to bronchodilators in COPD: curious enigma or clinically important phenotype?

Lancet Respir Med 2014 Nov 9;2(11):865-867. Epub 2014 Sep 9.

Imaging Research Laboratories, Robarts Research Institute, 1151 Richmond Street N, London, ON, Canada N6A 5B7; Department of Medical Biophysics, University of Western Ontario, London, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(14)70198-5DOI Listing
November 2014

Pulmonary functional magnetic resonance imaging: asthma temporal-spatial maps.

Acad Radiol 2014 Nov;21(11):1402-10

Imaging Research Laboratories, Robarts Research Institute, Western University, 1151 Richmond St North, London, Ontario, Canada N6A 5B7; Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada; Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Ontario, Canada; Department of Medical Imaging, The University of Western Ontario, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2014.08.002DOI Listing
November 2014

Three-dimensional carotid ultrasound plaque texture predicts vascular events.

Stroke 2014 Sep 17;45(9):2695-701. Epub 2014 Jul 17.

From the Biomedical Imaging Group Rotterdam, Departments of Medical Informatics and Radiology, Erasmus MC, Rotterdam, The Netherlands (A.v.E., W.J.N., M.d.B.); Stroke Prevention and Atherosclerosis Research Centre (T.W., J.D.S.), and Imaging Research Laboratories (G.P., A.F., J.D.S.), Robarts Research Institute, Western University, London, Canada; Department of Internal Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand (T.W.); Department of Imaging Science and Technology, Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands (W.J.N.); and Department of Computer Science, University of Copenhagen, Copenhagen, Denmark (M.d.B.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005752DOI Listing
September 2014

COPD imaging: new tools to tackle an old problem?

COPD 2014 Sep;11(5):477-9

1James Hogg Research Centre, The University of British Columbia & The Institute of Heart and Lung Health , St. Paul's Hospital, Vancouver , Canada.

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http://dx.doi.org/10.3109/15412555.2014.952968DOI Listing
September 2014

Longitudinal Computed Tomography and Magnetic Resonance Imaging of COPD: Thoracic Imaging Network of Canada (TINCan) Study Objectives.

Chronic Obstr Pulm Dis 2014 Sep 25;1(2):200-211. Epub 2014 Sep 25.

Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Canada.

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http://journal.copdfoundation.org/jcopdf/id/1035/Longitudina
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http://dx.doi.org/10.15326/jcopdf.1.2.2014.0136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556865PMC
September 2014

Pulmonary ventilation defects in older never-smokers.

J Appl Physiol (1985) 2014 Aug 5;117(3):297-306. Epub 2014 Jun 5.

Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada; Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada;

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http://dx.doi.org/10.1152/japplphysiol.00046.2014DOI Listing
August 2014

Using pulmonary imaging to move chronic obstructive pulmonary disease beyond FEV1.

Am J Respir Crit Care Med 2014 Jul;190(2):135-44

1 Department of Radiology, Vancouver General Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1164/rccm.201402-0256PPDOI Listing
July 2014

Hyperpolarized 3He and 129Xe magnetic resonance imaging apparent diffusion coefficients: physiological relevance in older never- and ex-smokers.

Physiol Rep 2014 Jul 16;2(7). Epub 2014 Jul 16.

Imaging Research Laboratories, Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada Graduate Program in Biomedical Engineering, The University of Western Ontario, London, Ontario, Canada Department of Medical Imaging, The University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.14814/phy2.12068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187551PMC
July 2014

Volume of carotid artery ulceration as a predictor of cardiovascular events.

Stroke 2014 May 8;45(5):1437-41. Epub 2014 Apr 8.

From the Department of Pathology and Toxicology, Schulich School of Medicine and Dentistry (M.K.), Department of Psychiatry (V.B.), Imaging Research Group, Robarts Research Institute (G.P., A.F., J.D.S.), and Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute (J.D.S.), Western University, London, Ontario, Canada; and Department of Internal Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand (T.W.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005163DOI Listing
May 2014

What are ventilation defects in asthma?

Thorax 2014 Jan 16;69(1):63-71. Epub 2013 Aug 16.

Imaging Research Laboratories, Robarts Research Institute, , London, Ontario, Canada.

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http://dx.doi.org/10.1136/thoraxjnl-2013-203711DOI Listing
January 2014

Lung morphometry using hyperpolarized (129) Xe apparent diffusion coefficient anisotropy in chronic obstructive pulmonary disease.

Magn Reson Med 2013 Dec 28;70(6):1699-706. Epub 2013 Jan 28.

Ph.D., Imaging Research Laboratories, Robarts Research Institute, Western University, London, Ontario, Canada.

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http://doi.wiley.com/10.1002/mrm.24595
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http://dx.doi.org/10.1002/mrm.24595DOI Listing
December 2013

Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.

J Magn Reson Imaging 2013 Dec 15;38(6):1521-30. Epub 2013 Apr 15.

Imaging Research Laboratories, Robarts Research Institute, London, Canada; Department of Medical Biophysics, The University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/jmri.24111DOI Listing
December 2013

Semi-automated scoring of pulmonary emphysema from X-ray CT: trainee reproducibility and accuracy.

Eur J Radiol 2013 Nov 17;82(11):e734-41. Epub 2013 Aug 17.

Imaging Research Laboratories, Robarts Research Institute, London, Canada; Graduate Program in Biomedical Engineering. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2013.07.013DOI Listing
November 2013

Pulmonary functional imaging using hyperpolarized noble gas MRI: six years of start-up experience at a single site.

Acad Radiol 2013 Nov;20(11):1344-56

Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada, N6A 5K8; Department of Medical Biophysics, London, Canada.

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http://dx.doi.org/10.1016/j.acra.2013.02.020DOI Listing
November 2013

Pulmonary functional magnetic resonance imaging for paediatric lung disease.

Paediatr Respir Rev 2013 Sep 20;14(3):180-9. Epub 2013 Mar 20.

Imaging Research Laboratories, Robarts Research Institute, London, Canada.

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http://dx.doi.org/10.1016/j.prrv.2013.02.007DOI Listing
September 2013

Progression of carotid plaque volume predicts cardiovascular events.

Stroke 2013 Jul 4;44(7):1859-65. Epub 2013 Jun 4.

Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.113.001461DOI Listing
July 2013

Hyperpolarized helium-3 magnetic resonance imaging of chronic obstructive pulmonary disease exacerbation.

J Magn Reson Imaging 2013 May 2;37(5):1223-7. Epub 2012 Nov 2.

Imaging Research Laboratories, Robarts Research Institute, London, Canada; Department of Medical Biophysics, University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1002/jmri.23896DOI Listing
May 2013

Computed tomography density histogram analysis to evaluate pulmonary emphysema in ex-smokers.

Acad Radiol 2013 May;20(5):537-45

Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Canada N6A 5K8.

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http://dx.doi.org/10.1016/j.acra.2012.11.010DOI Listing
May 2013

Hyperpolarized (3)He magnetic resonance imaging: comparison with four-dimensional x-ray computed tomography imaging in lung cancer.

Acad Radiol 2012 Dec 19;19(12):1546-53. Epub 2012 Sep 19.

Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, ON N6A 5K8, Canada.

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http://dx.doi.org/10.1016/j.acra.2012.08.007DOI Listing
December 2012

Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease.

Radiology 2012 Nov 5;265(2):600-10. Epub 2012 Sep 5.

Imaging Research Laboratories, Robarts Research Institute, 100 Perth Dr, London, ON, Canada N6A 5K8.

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http://dx.doi.org/10.1148/radiol.12120485DOI Listing
November 2012

Evidence of adult lung growth in humans.

N Engl J Med 2012 10;367(16):1566-7; author reply 1567

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http://dx.doi.org/10.1056/NEJMc1209904DOI Listing
October 2012