Grace Chen

Grace Chen

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4-Substituted 2-amino-3,4-dihydroquinazolines with a 3-hairpin turn side chain as novel inhibitors of BACE-1.

Bioorg Chem 2020 Jan 22;95:103135. Epub 2019 Jul 22.

School of Pharmacy, College of Medicine and Center for Innovative Therapeutics Discovery, National Taiwan University, No. 33, Lin Sen South Road, Taipei 10050, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103135DOI Listing
January 2020

N6-Methyladenosine Modification Controls Circular RNA Immunity.

Mol Cell 2019 10 29;76(1):96-109.e9. Epub 2019 Aug 29.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778039PMC
October 2019

Occupation and motor neuron disease: a New Zealand case-control study.

Occup Environ Med 2019 05 22;76(5):309-316. Epub 2019 Mar 22.

Centre for Public Health Research, Massey University, Wellington, New Zealand.

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http://dx.doi.org/10.1136/oemed-2018-105605DOI Listing
May 2019

Outer surface protein polymorphisms linked to host-spirochete association in Lyme borreliae.

Mol Microbiol 2019 04 27;111(4):868-882. Epub 2019 Feb 27.

Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA.

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http://dx.doi.org/10.1111/mmi.14209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510028PMC
April 2019

A Method for Isolation and Proteomic Analysis of Outer Membrane Vesicles from Fecal Samples by LC-MS/MS.

J Proteomics Bioinform 2019 18;12(2):38-42. Epub 2019 Mar 18.

Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.4172/0974-276X.1000494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497448PMC
March 2019

Chromatin laser imaging reveals abnormal nuclear changes for early cancer detection.

Biomed Opt Express 2019 Feb 24;10(2):838-854. Epub 2019 Jan 24.

Department of Biomedical Engineering, University of Michigan, 1101 Beal Ave., Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1364/BOE.10.000838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377874PMC
February 2019

Epitope-Specific Serological Assays for RSV: Conformation Matters.

Vaccines (Basel) 2019 Feb 23;7(1). Epub 2019 Feb 23.

Vaccine Research Center, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.3390/vaccines7010023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466065PMC
February 2019

A Randomized Trial Evaluating School-Based Mindfulness Intervention for Ethnic Minority Youth: Exploring Mediators and Moderators of Intervention Effects.

J Abnorm Child Psychol 2019 01;47(1):1-19

Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/s10802-018-0425-7DOI Listing
January 2019

Acrylamide Functional Group Incorporation Improves Drug-like Properties: An Example with EGFR Inhibitors.

ACS Med Chem Lett 2019 Jan 6;10(1):22-26. Epub 2018 Dec 6.

School of Pharmacy and Center for Innovative Therapeutics Discovery, National Taiwan University, Taipei 10055, Taiwan.

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http://dx.doi.org/10.1021/acsmedchemlett.8b00270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331160PMC
January 2019

Flavonoids and Colorectal Cancer Prevention.

Antioxidants (Basel) 2018 Dec 10;7(12). Epub 2018 Dec 10.

Division of Hematology & Oncology, Department of Internal Medicine, Rogel Cancer Center, University of Michigan, Ann Abor, MI 48109, USA.

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http://dx.doi.org/10.3390/antiox7120187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316869PMC
December 2018

Effects of Intrinsic Factors on the Clinical Pharmacokinetics of Vortioxetine.

Clin Pharmacol Drug Dev 2018 11 19;7(8):880-888. Epub 2018 Jun 19.

Takeda Pharmaceuticals U.S.A., Inc., Deerfield, IL, USA.

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http://doi.wiley.com/10.1002/cpdd.577
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http://dx.doi.org/10.1002/cpdd.577DOI Listing
November 2018

Myc-Associated Zinc Finger Protein Regulates the Proinflammatory Response in Colitis and Colon Cancer via STAT3 Signaling.

Mol Cell Biol 2018 11 29;38(22). Epub 2018 Oct 29.

Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA

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http://dx.doi.org/10.1128/MCB.00386-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206459PMC
November 2018

The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.

Cell 2018 11 1;175(6):1651-1664.e14. Epub 2018 Nov 1.

Department of Pathology and Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183125
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http://dx.doi.org/10.1016/j.cell.2018.09.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294477PMC
November 2018

Sex and Gender Differences Research Design for Basic, Clinical, and Population Studies: Essentials for Investigators.

Endocr Rev 2018 08;39(4):424-439

Division of Women's Health, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1210/er.2017-00246DOI Listing
August 2018

Junk Food Exposure Disrupts Selection of Food-Seeking Actions in Rats.

Front Psychiatry 2018 16;9:350. Epub 2018 Aug 16.

Department of Psychiatry and Biobehavioral Sciences, Hatos Center for Neuropharmacology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.

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http://dx.doi.org/10.3389/fpsyt.2018.00350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106797PMC
August 2018

Vortioxetine: Clinical Pharmacokinetics and Drug Interactions.

Clin Pharmacokinet 2018 06;57(6):673-686

Department of Clinical Science, Takeda Development Center Americas, Inc., Deerfield, IL, USA.

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http://dx.doi.org/10.1007/s40262-017-0612-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973995PMC
June 2018

Advancing Sex- and Gender-Informed Approaches to Health in an Academic Medical Center.

Womens Health Issues 2018 Mar - Apr;28(2):117-121. Epub 2017 Dec 15.

Wellesley College, Wellesley, Massachusetts.

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http://dx.doi.org/10.1016/j.whi.2017.11.004DOI Listing
May 2018

The Role of the Gut Microbiome in Colorectal Cancer.

Authors:
Grace Y Chen

Clin Colon Rectal Surg 2018 May 1;31(3):192-198. Epub 2018 Apr 1.

Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1055/s-0037-1602239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929887PMC
May 2018

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

Elife 2017 10 31;6. Epub 2017 Oct 31.

Department of Developmental Biology, Stanford University School of Medicine, Stanford, United States.

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http://dx.doi.org/10.7554/eLife.26116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703642PMC
October 2017

A transgene design for enhancing oil content in Arabidopsis and Camelina seeds.

Biotechnol Biofuels 2018 21;11:46. Epub 2018 Feb 21.

1Joint BioEnergy Institute and Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA.

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http://dx.doi.org/10.1186/s13068-018-1049-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820799PMC
February 2018

LncRNA Seduction of GOT2 Goes Viral.

Immunity 2017 12;47(6):1021-1023

Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.12.006DOI Listing
December 2017

A Seed Mismatch Enhances Argonaute2-Catalyzed Cleavage and Partially Rescues Severely Impaired Cleavage Found in Fish.

Mol Cell 2017 12;68(6):1095-1107.e5

Howard Hughes Medical Institute, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.11.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821252PMC
December 2017

The effect of CT26 tumor-derived TGF-β on the balance of tumor growth and immunity.

Immunol Lett 2017 11 3;191:47-54. Epub 2017 Oct 3.

Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2017.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648350PMC
November 2017

Banning Asbestos in New Zealand, 1936-2016, an 80-Year Long Saga.

Int J Environ Res Public Health 2017 11 25;14(12). Epub 2017 Nov 25.

Respiratory Physician, Hawke's Bay, Hastings 4120, New Zealand.

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http://dx.doi.org/10.3390/ijerph14121457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750876PMC
November 2017

Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration.

Bioorg Med Chem Lett 2017 10 7;27(20):4673-4677. Epub 2017 Sep 7.

Enteroendocrine Discovery Performance Unit and Platform Technologies and Science, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, United States.

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http://dx.doi.org/10.1016/j.bmcl.2017.09.008DOI Listing
October 2017

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

Elife 2017 10 31;6. Epub 2017 Oct 31.

Department of Developmental Biology, Stanford University School of Medicine, Stanford, United States.

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http://dx.doi.org/10.7554/eLife.26116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703642PMC
October 2017

AICAR Administration Attenuates Hemorrhagic Hyperglycemia and Lowers Oxygen Debt in Anesthetized Male Rabbits.

Front Physiol 2017 13;8:692. Epub 2017 Sep 13.

Department of Emergency Medicine, Virginia Commonwealth UniversityRichmond, VA, United States.

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http://dx.doi.org/10.3389/fphys.2017.00692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601404PMC
September 2017

Gene regulation in the immune system by long noncoding RNAs.

Nat Immunol 2017 Aug;18(9):962-972

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/ni.3771DOI Listing
August 2017

Sensing Self and Foreign Circular RNAs by Intron Identity.

Mol Cell 2017 Jul 15;67(2):228-238.e5. Epub 2017 Jun 15.

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610545PMC
July 2017

Regulation of the gut microbiome by inflammasomes.

Authors:
Grace Y Chen

Free Radic Biol Med 2017 04 12;105:35-40. Epub 2016 Nov 12.

Division of Hematology & Oncology, Department of Internal Medicine, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401786PMC
April 2017

Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist.

Bioorg Med Chem Lett 2017 03 17;27(5):1278-1283. Epub 2017 Jan 17.

GlaxoSmithKline, Enteroendocrine Discovery Performance Unit and Platform Technology and Science, 5 Moore Drive, Research Triangle Park, NC 27709, United States.

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http://dx.doi.org/10.1016/j.bmcl.2017.01.034DOI Listing
March 2017

Targeting Mac-1-mediated leukocyte-RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage.

Exp Hematol 2016 10 5;44(10):940-6. Epub 2016 Jul 5.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Department of Medicine and Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.06.252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467695PMC
October 2016

Development of an Integrated Pipeline for Profiling Microbial Proteins from Mouse Fecal Samples by LC-MS/MS.

J Proteome Res 2016 10 2;15(10):3635-3642. Epub 2016 Sep 2.

Department of Surgery, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291289PMC
October 2016

Lack of Effect of Vortioxetine on the Pharmacokinetics and Pharmacodynamics of Ethanol, Diazepam, and Lithium.

Clin Pharmacokinet 2016 09;55(9):1115-27

Analytical Science, Takeda Development Center Americas, Inc., One Takeda Parkway, Deerfield, IL, 60015, USA.

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http://dx.doi.org/10.1007/s40262-016-0389-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996894PMC
September 2016

Quantitative evaluation of changes in gait after extended cerebrospinal fluid drainage for normal pressure hydrocephalus.

J Clin Neurosci 2016 Jun 7;28:31-7. Epub 2016 Jan 7.

Adult Hydrocephalus Program, Department of Neurosurgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2015.11.013DOI Listing
June 2016

Nod1 Limits Colitis-Associated Tumorigenesis by Regulating IFN-γ Production.

J Immunol 2016 06 6;196(12):5121-9. Epub 2016 May 6.

Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1501822
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http://dx.doi.org/10.4049/jimmunol.1501822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893968PMC
June 2016

Manipulation of the Gut Microbiota Reveals Role in Colon Tumorigenesis.

mSphere 2016 Jan-Feb;1(1). Epub 2015 Nov 4.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1128/mSphere.00001-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863627PMC
June 2016

Transcriptome analysis and identification of genes associated with ω-3 fatty acid biosynthesis in Perilla frutescens (L.) var. frutescens.

BMC Genomics 2016 06 24;17:474. Epub 2016 Jun 24.

Department of Bioindustry and Bioresource Engineering, Plant Engineering Research Institute, Sejong University, Seoul, 05006, Republic of Korea.

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http://dx.doi.org/10.1186/s12864-016-2805-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920993PMC
June 2016

Minimally invasive procedures for neuropathic pain.

Pain Manag 2016 Apr 18;6(2):103-9. Epub 2016 Mar 18.

Comprehensive Pain Management Center, Oregon Health & Science University, Center for Health & Healing, 3303 SW Bond Avenue, Portland, OR 97239, USA.

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http://dx.doi.org/10.2217/pmt.15.61DOI Listing
April 2016

Hybrid Polymer/UiO-66(Zr) and Polymer/NaY Fiber Sorbents for Mercaptan Removal from Natural Gas.

ACS Appl Mater Interfaces 2016 Apr 5;8(15):9700-9. Epub 2016 Apr 5.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology , 311 Ferst Drive, Atlanta, Georgia 30332-0100, United States.

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http://dx.doi.org/10.1021/acsami.6b00897DOI Listing
April 2016

Expression of Castor LPAT2 Enhances Ricinoleic Acid Content at the sn-2 Position of Triacylglycerols in Lesquerella Seed.

Int J Mol Sci 2016 Apr 6;17(4):507. Epub 2016 Apr 6.

Western Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, 800 Buchanan St., Albany, CA 94710, USA.

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http://dx.doi.org/10.3390/ijms17040507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848963PMC
April 2016

Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children.

mBio 2016 Feb 16;7(1):e01300-15. Epub 2016 Feb 16.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA

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http://dx.doi.org/10.1128/mBio.01300-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791846PMC
February 2016

Measurement invariance of the people of Color Racial Identity Attitudes Scale with Asian Americans.

Psychol Assess 2016 Jan 20;28(1):116-22. Epub 2015 Jul 20.

Department of Psychology, University of Maryland.

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http://dx.doi.org/10.1037/pas0000161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710547PMC
January 2016

A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease models.

Nat Commun 2014 ;5:3276

Department of Chemistry, National University of Singapore, Singapore 117543, Singapore.

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http://dx.doi.org/10.1038/ncomms4276DOI Listing
November 2015

Leveraging Cancer Therapeutics for the HIV Cure Agenda: Current Status and Future Directions.

Drugs 2015 Sep;75(13):1447-59

HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, 5601 Fishers Lane, Bethesda, MD, 20892, USA,

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http://dx.doi.org/10.1007/s40265-015-0426-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561022PMC
September 2015

Neutrophil ageing is regulated by the microbiome.

Nature 2015 Sep 16;525(7570):528-32. Epub 2015 Sep 16.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nature15367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712631PMC
September 2015

Dissecting CD8+ NKT Cell Responses to Listeria Infection Reveals a Component of Innate Resistance.

J Immunol 2015 Aug 26;195(3):1112-20. Epub 2015 Jun 26.

Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109; and

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http://dx.doi.org/10.4049/jimmunol.1500084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506885PMC
August 2015

The effect of warm-up on surgical performance: a systematic review.

Surg Endosc 2015 Jun 23;29(6):1259-69. Epub 2014 Aug 23.

Department of Surgery, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Suite 399A, 4940 Eastern Avenue, Baltimore, MD, 21224, USA,

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http://dx.doi.org/10.1007/s00464-014-3811-4DOI Listing
June 2015

Lack of effect of multiple doses of vortioxetine on the pharmacokinetics and pharmacodynamics of aspirin and warfarin.

J Clin Pharmacol 2015 Jun 4;55(6):671-9. Epub 2015 Feb 4.

Takeda Development Center Americas, One Takeda Parkway, Deerfield, IL, USA.

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http://dx.doi.org/10.1002/jcph.456DOI Listing
June 2015

The nucleotide exchange factors Grp170 and Sil1 induce cholera toxin release from BiP to enable retrotranslocation.

Mol Biol Cell 2015 Jun 15;26(12):2181-9. Epub 2015 Apr 15.

Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48103

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https://www.molbiolcell.org/doi/10.1091/mbc.E15-01-0014
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http://dx.doi.org/10.1091/mbc.E15-01-0014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462937PMC
June 2015

Preoperative warm-up the key to improved resident technique: a randomized study.

Surg Endosc 2015 May 24;29(5):1057-63. Epub 2014 Sep 24.

Department of Surgery, Johns Hopkins University School of Medicine, Suite 399, 4940 Eastern Ave 21224, Baltimore, MD, 21287, USA,

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http://dx.doi.org/10.1007/s00464-014-3778-1DOI Listing
May 2015

A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth.

Neuropharmacology 2015 May 14;92:146-57. Epub 2015 Jan 14.

School of Pharmacy, National Taiwan University, No. 33, Lin-Sen South Road, Taipei, 10051, Taiwan, ROC; Center for Innovative Therapeutics Discovery, National Taiwan University, No. 33, Lin-Ssen South Road, Taipei, 10051, Taiwan, ROC; Department of Life Science, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei, 10617, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.01.004DOI Listing
May 2015

Current progress towards the metabolic engineering of plant seed oil for hydroxy fatty acids production.

Plant Cell Rep 2015 Apr 11;34(4):603-15. Epub 2015 Jan 11.

Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration, Jeonju, 560-500, Republic of Korea.

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http://dx.doi.org/10.1007/s00299-015-1736-6DOI Listing
April 2015

Identification of hydroxy fatty acid and triacylglycerol metabolism-related genes in lesquerella through seed transcriptome analysis.

BMC Genomics 2015 Mar 24;16:230. Epub 2015 Mar 24.

U.S. Department of Agriculture, Western Regional Research Center, Agricultural Research Service, 800 Buchanan Street, Albany, CA, 94710, USA.

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http://link.springer.com/content/pdf/10.1186%2Fs12864-015-14
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http://www.biomedcentral.com/1471-2164/16/230
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http://dx.doi.org/10.1186/s12864-015-1413-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381405PMC
March 2015

Screening for autism spectrum disorders in 12-month-old high-risk siblings by parental report.

J Autism Dev Disord 2015 Jan;45(1):221-9

Developmental and Behavioral Pediatrics, Mike O'Callaghan Federal Medical Center, 4700 Las Vegas Boulevard North, Building 1300, Nellis Air Force Base, NV, 89191, USA,

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http://dx.doi.org/10.1007/s10803-014-2211-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289092PMC
January 2015

Population pharmacokinetic meta-analysis of vortioxetine in healthy individuals.

Basic Clin Pharmacol Toxicol 2014 Dec 22;115(6):552-9. Epub 2014 May 22.

Division of Clinical and Quantitative Pharmacology, H. Lundbeck A/S, Valby, Denmark.

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http://dx.doi.org/10.1111/bcpt.12256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257570PMC
December 2014

Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia.

Eur J Med Chem 2014 Oct 30;85:268-88. Epub 2014 Jul 30.

School of Pharmacy and Center for Innovative Therapeutics Discovery, National Taiwan University, No. 33, Lin Sen South Road, Taipei 10050, Taiwan; Department of Life Science, College of Life Science, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.07.108DOI Listing
October 2014

Bioisosteric replacement of an acylureido moiety attached to an indolin-2-one scaffold with a malonamido or a 2/4-pyridinoylamido moiety produces a selectively potent Aurora-B inhibitor.

Eur J Med Chem 2014 Sep 10;84:312-34. Epub 2014 Jul 10.

School of Pharmacy and Center for Innovative Therapeutics Discovery, National Taiwan University, No. 33, LinSen South Road, Taipei 10051, Taiwan; Department of Life Science, College of Life Science, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.07.033DOI Listing
September 2014

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).

Bioorg Med Chem Lett 2014 Jul 16;24(14):3100-3. Epub 2014 May 16.

Enteroendocrine Discovery Performance Unit, GlaxoSmithKline, PO Box 13398, Research Triangle Park, NC 27705, United States.

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http://dx.doi.org/10.1016/j.bmcl.2014.05.012DOI Listing
July 2014

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease.

Blood 2014 Jun 11;123(24):3818-27. Epub 2014 Mar 11.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY;

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http://dx.doi.org/10.1182/blood-2013-10-529982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055928PMC
June 2014

Structure of the gut microbiome following colonization with human feces determines colonic tumor burden.

Microbiome 2014 17;2:20. Epub 2014 Jun 17.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1186/2049-2618-2-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070349PMC
June 2014

Unification of methods for estimating the strength of reproductive isolation.

Evolution 2014 May 18;68(5):1511-22. Epub 2014 Feb 18.

Department of Plant Biology, Ecology, Evolutionary Biology, and Behavior Program, Michigan State University, East Lansing, Michigan, 48824.

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http://dx.doi.org/10.1111/evo.12362DOI Listing
May 2014

Poly(A)-tail profiling reveals an embryonic switch in translational control.

Nature 2014 Apr 29;508(7494):66-71. Epub 2014 Jan 29.

1] Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA [2] Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA [3] Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/nature13007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086860PMC
April 2014

Mucus, it is not just a static barrier.

Sci Signal 2014 Apr 29;7(323):pe11. Epub 2014 Apr 29.

1Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan Cancer Center, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1126/scisignal.2005357DOI Listing
April 2014

Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis.

Authors:
Grace Y Chen

Eur J Immunol 2014 Feb 16;44(2):321-7. Epub 2014 Jan 16.

Division of Hematology and Oncology, Department of Internal Medicine, and Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1002/eji.201344135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932540PMC
February 2014

Gut microbiota protects against gastrointestinal tumorigenesis caused by epithelial injury.

Cancer Res 2013 Dec 28;73(24):7199-210. Epub 2013 Oct 28.

Authors' Affiliations: Division of Hematology and Oncology, Department of Internal Medicine, Department of Pathology, Comprehensive Cancer Center, Unit for Laboratory Animal Medicine, and Department of Microbiology and Immunology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883499PMC
December 2013

Preparation of small-molecule microarrays by trans-cyclooctene tetrazine ligation and their application in the high-throughput screening of protein-protein interaction inhibitors of bromodomains.

Angew Chem Int Ed Engl 2013 Dec 4;52(52):14060-4. Epub 2013 Nov 4.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore) http://staff.science.nus.edu.sg/∼syao.

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http://dx.doi.org/10.1002/anie.201307803DOI Listing
December 2013

Patients with chronic pain.

Med Clin North Am 2013 Nov 14;97(6):1201-15. Epub 2013 Sep 14.

Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, 3303 Southwest Bond Avenue, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.mcna.2013.07.005DOI Listing
November 2013

The gut microbiome modulates colon tumorigenesis.

mBio 2013 Nov 5;4(6):e00692-13. Epub 2013 Nov 5.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.

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http://mbio.asm.org/cgi/doi/10.1128/mBio.00692-13
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http://dx.doi.org/10.1128/mBio.00692-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892781PMC
November 2013

Pharmacokinetic drug interactions involving vortioxetine (Lu AA21004), a multimodal antidepressant.

Clin Drug Investig 2013 Oct;33(10):727-36

Clinical Pharmacology, Takeda Development Center Americas, One Takeda Parkway, Deerfield, IL, 60015, USA,

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http://dx.doi.org/10.1007/s40261-013-0117-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775155PMC
October 2013

Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling.

Angew Chem Int Ed Engl 2013 Aug 10;52(33):8551-6. Epub 2013 Jun 10.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

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http://dx.doi.org/10.1002/anie.201300683DOI Listing
August 2013

Control of pathogens and pathobionts by the gut microbiota.

Nat Immunol 2013 Jul;14(7):685-90

Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/ni.2608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083503PMC
July 2013

Recent advances in microarray technologies for proteomics.

Chem Biol 2013 May;20(5):685-99

Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, PRC.

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http://dx.doi.org/10.1016/j.chembiol.2013.04.009DOI Listing
May 2013