Publications by authors named "Gou Young Koh"

100Publications

Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi.

Nat Commun 2020 08 14;11(1):4102. Epub 2020 Aug 14.

Center for Vascular Research, Institute for Basic Science (IBS), Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1038/s41467-020-17886-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428020PMC
August 2020

VEGFR2 signaling drives meningeal vascular regeneration upon head injury.

Nat Commun 2020 07 31;11(1):3866. Epub 2020 Jul 31.

KI for Bio-century, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1038/s41467-020-17545-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395111PMC
July 2020

Biological functions of lymphatic vessels.

Science 2020 07;369(6500)

Center for Vascular Research, Institute for Basic Science, Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1126/science.aax4063DOI Listing
July 2020

Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid.

Nature 2019 08 24;572(7767):62-66. Epub 2019 Jul 24.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.

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http://dx.doi.org/10.1038/s41586-019-1419-5DOI Listing
August 2019

A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis.

Nat Commun 2019 02 19;10(1):838. Epub 2019 Feb 19.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Korea.

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http://dx.doi.org/10.1038/s41467-019-08773-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381131PMC
February 2019

Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation.

Science 2019 02 7;363(6427):644-649. Epub 2019 Feb 7.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.

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http://dx.doi.org/10.1126/science.aav0173DOI Listing
February 2019

β-Cell-Derived Angiopoietin-1 Regulates Insulin Secretion and Glucose Homeostasis by Stabilizing the Islet Microenvironment.

Diabetes 2019 04 6;68(4):774-786. Epub 2019 Feb 6.

Department of Internal Medicine, Yonsei University College of Medicine, Yonsei University, Seoul, South Korea

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db18
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http://dx.doi.org/10.2337/db18-0864DOI Listing
April 2019

Neutrophils disturb pulmonary microcirculation in sepsis-induced acute lung injury.

Eur Respir J 2019 03 28;53(3). Epub 2019 Mar 28.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00786
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http://dx.doi.org/10.1183/13993003.00786-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437604PMC
March 2019

YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis.

Circ Res 2019 01;124(2):225-242

From the Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon (H.C., J.H.A., D.-S.L., G.Y.K.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31370
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http://dx.doi.org/10.1161/CIRCRESAHA.118.313707DOI Listing
January 2019

Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction.

J Clin Invest 2018 11 8;128(11):5018-5033. Epub 2018 Oct 8.

Center for Vascular Research, Institute for Basic Science, Daejeon, South Korea.

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http://dx.doi.org/10.1172/JCI99659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205384PMC
November 2018

Morphological Analysis of Lacteal Structure in the Small Intestine of Adult Mice.

Methods Mol Biol 2018 ;1846:131-139

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

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http://dx.doi.org/10.1007/978-1-4939-8712-2_8DOI Listing
May 2019

VEGF-Grab Enhances the Efficacy of Radiation Therapy by Blocking VEGF-A and Treatment-Induced PlGF.

Int J Radiat Oncol Biol Phys 2018 11 11;102(3):609-618. Epub 2018 Jul 11.

Institute for Innovative Cancer Research, Asan Medical Center, Seoul, Republic of Korea; Center for Advancing Cancer Therapeutics, Asan Medical Center, Seoul, Republic of Korea; Department of Radiation Oncology, Asan Medical Center, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.06.401DOI Listing
November 2018

Pulmonary pericytes regulate lung morphogenesis.

Nat Commun 2018 06 22;9(1):2448. Epub 2018 Jun 22.

Department of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine, and University of Münster, Faculty of Medicine, D-48149, Münster, Germany.

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http://dx.doi.org/10.1038/s41467-018-04913-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015030PMC
June 2018

Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.

Cell Rep 2018 05;23(8):2455-2466

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; Center for Vascular Research, Institute for Basic Science (IBS), Daejeon 34141, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.080DOI Listing
May 2018

YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC.

Cancer Res 2018 06 18;78(12):3306-3320. Epub 2018 Apr 18.

National Creative Research Initiatives Center for Cell Division and Differentiation, Department of Biological Sciences, KAIST, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-3487DOI Listing
June 2018

Organ-specific lymphatic vasculature: From development to pathophysiology.

J Exp Med 2018 01 14;215(1):35-49. Epub 2017 Dec 14.

Center for Vascular Research, Institute for Basic Science, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

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http://dx.doi.org/10.1084/jem.20171868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748863PMC
January 2018

HSP90 inhibitor (NVP-AUY922) enhances the anti-cancer effect of BCL-2 inhibitor (ABT-737) in small cell lung cancer expressing BCL-2.

Cancer Lett 2017 12 4;411:19-26. Epub 2017 Oct 4.

Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.09.040DOI Listing
December 2017

Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma.

J Clin Invest 2017 Oct 18;127(10):3877-3896. Epub 2017 Sep 18.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

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http://dx.doi.org/10.1172/JCI94668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617682PMC
October 2017

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation.

J Clin Invest 2017 Sep 14;127(9):3441-3461. Epub 2017 Aug 14.

Center for Vascular Research, Institute for Basic Science, Daejeon, South Korea.

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http://dx.doi.org/10.1172/JCI93825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669570PMC
September 2017

Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology.

Science 2017 08 3;357(6353). Epub 2017 Aug 3.

Center for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1126/science.aal2379DOI Listing
August 2017

Plastic roles of pericytes in the blood-retinal barrier.

Nat Commun 2017 05 16;8:15296. Epub 2017 May 16.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.

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http://dx.doi.org/10.1038/ncomms15296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440855PMC
May 2017

Generation of PDGFRα Cardioblasts from Pluripotent Stem Cells.

Sci Rep 2017 02 6;7:41840. Epub 2017 Feb 6.

Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

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http://dx.doi.org/10.1038/srep41840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292955PMC
February 2017

Taking aim at Sox18.

Elife 2017 01 31;6. Epub 2017 Jan 31.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.7554/eLife.24238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283827PMC
January 2017

Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment.

Cancer Cell 2016 Dec;30(6):953-967

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; Center for Vascular Research, Institute for Basic Science (IBS), Daejeon 34141, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108163050
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http://dx.doi.org/10.1016/j.ccell.2016.10.018DOI Listing
December 2016

Antiangiogenic Therapy Induces Hepatic Tumor Vascular Network Rearrangement to Receive Perfusion via the Portal Vein and Hepatic Artery.

J Vasc Res 2016 20;53(1-2):72-82. Epub 2016 Sep 20.

Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1159/000448734DOI Listing
May 2017

Coordinated lymphangiogenesis is critical in lymph node development and maturation.

Dev Dyn 2016 12 3;245(12):1189-1197. Epub 2016 Oct 3.

Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701, Korea.

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http://dx.doi.org/10.1002/dvdy.24456DOI Listing
December 2016

SoxF Transcription Factors Are Positive Feedback Regulators of VEGF Signaling.

Circ Res 2016 Sep 15;119(7):839-52. Epub 2016 Aug 15.

From the Department of Biological Sciences (K.K., J.W.K., G.Y.K., I.K.), Graduate School of Medical Science and Engineering (I.-K.K., J.M.Y., B.I.K., S.L., G.Y.K., I.K.), Biomedical Science and Engineering Interdisciplinary Program (E.L., G.Y.K., I.K.), and Department of Bio and Brain Engineering (J.P., C.C.), Korea Advanced Institute of Science and Technology, Daejeon; Center for Vascular Research, Institute for Basic Science, Daejeon, Republic of Korea (K.K., S.S., G.Y.K.); Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Hospital, Gwangju, Republic of Korea (S.L.); and The Laboratory of Vascular Biology, Keio University, Tokyo, Japan (Y.K.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308483DOI Listing
September 2016

PEGylation and HAylation via catechol: α-Amine-specific reaction at N-terminus of peptides and proteins.

Acta Biomater 2016 10 14;43:50-60. Epub 2016 Jul 14.

Department of Chemistry, KAIST, BK21 Plus Program, 291 University Rd., Yuseong-gu, Daejeon 305-701, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.07.018DOI Listing
October 2016

Amelioration of sepsis by TIE2 activation-induced vascular protection.

Sci Transl Med 2016 04;8(335):335ra55

Center for Vascular Research, Institute for Basic Science, Daejeon 305-701, Republic of Korea. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.

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http://dx.doi.org/10.1126/scitranslmed.aad9260DOI Listing
April 2016

Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis.

Nat Commun 2016 Jan 13;7:10347. Epub 2016 Jan 13.

Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University, Seoul 151-742, South Korea.

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http://dx.doi.org/10.1038/ncomms10347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735525PMC
January 2016

A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner.

Sci Rep 2015 Oct 19;5:15291. Epub 2015 Oct 19.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701, Korea.

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http://dx.doi.org/10.1038/srep15291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609988PMC
October 2015

Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion.

Development 2015 Aug;142(15):2623-32

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea

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http://dev.biologists.org/lookup/doi/10.1242/dev.125336
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http://dx.doi.org/10.1242/dev.125336DOI Listing
August 2015

Mouse Hepatic Tumor Vascular Imaging by Experimental Selective Angiography.

PLoS One 2015 1;10(7):e0131687. Epub 2015 Jul 1.

Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131687PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489182PMC
April 2016

The pericyte as a cellular regulator of penile erection and a novel therapeutic target for erectile dysfunction.

Sci Rep 2015 Jun 5;5:10891. Epub 2015 Jun 5.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon 400-711, Republic of Korea.

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http://dx.doi.org/10.1038/srep10891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456662PMC
June 2015

Bioluminescence-activated deep-tissue photodynamic therapy of cancer.

Theranostics 2015 18;5(8):805-17. Epub 2015 Apr 18.

1. Graduate School of Nanoscience and Technology (WCU), Korea Advanced Institute of Science and Technology, 291 Daehak-Ro, Yusong-Gu, Daejon 305-701, Korea ; 5. Wellman Center for Photomedicine, Massachusetts General Hospital, 65 Landsdowne St. UP-525, Cambridge, MA 02139, USA ; 7. Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, 40 Blossom St. Boston, MA 02114, USA.

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http://dx.doi.org/10.7150/thno.11520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440439PMC
February 2016

COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway.

Exp Neurobiol 2015 Mar 13;24(1):55-70. Epub 2015 Mar 13.

Department of Neurosurgery, Seoul National University College of Medicine, Seoul 110-744, Korea. ; Cancer Research Institute, Seoul National University College of Medicine, Seoul 110-744, Korea. ; Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 110-744, Korea.

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http://dx.doi.org/10.5607/en.2015.24.1.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363334PMC
March 2015

Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse.

Sci Rep 2015 Mar 18;5:9222. Epub 2015 Mar 18.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon 400-711, Republic of Korea.

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http://dx.doi.org/10.1038/srep09222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363832PMC
March 2015

Deficiency of endothelium-specific transcription factor Sox17 induces intracranial aneurysm.

Circulation 2015 Mar 16;131(11):995-1005. Epub 2015 Jan 16.

From Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea (S.L., I.-K.K., S.S., G.Y.K., I.K.); Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Republic of Korea (J.S.A.); Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea (D.-C.W., S.-T.K.); Department of Forensic Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea (H.-S.K.); and Department of Physiology, School of Medicine, Chungnam National University, Daejeon, Republic of Korea (B.H.J.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.012568DOI Listing
March 2015

Angiopoietin-1 blocks neurotoxic zinc entry into cortical cells via PIP2 hydrolysis-mediated ion channel inhibition.

Neurobiol Dis 2015 Sep 9;81:203-13. Epub 2014 Nov 9.

Neural Injury Research Lab, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea; Department of Neurology, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.11.001DOI Listing
September 2015

Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse.

Proc Natl Acad Sci U S A 2014 Jul 16;111(26):E2731-40. Epub 2014 Jun 16.

National Research Center for Sexual Medicine andDepartment of Urology, Inha University School of Medicine, Incheon 400-711, Korea;

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http://dx.doi.org/10.1073/pnas.1403471111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084468PMC
July 2014

Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis.

Arterioscler Thromb Vasc Biol 2014 Aug 19;34(8):1697-703. Epub 2014 Jun 19.

From the Department of Life Sciences (J.G., J.-S.M., C.S.L., P.S., A.L., D.K., J.H.Y., B.J.K, J.-M.K., K.L.K., Y.R.Y., Y.K., S.-H.K., P.-G.S., Y.-Y.K., S.H.R.), School of Interdisciplinary Bioscience and Bioengineering (J.-H.J., D.H., S.H.R.), Division of Integrative Biosciences and Biotechnology (C.C., S.H.R.), and Department of Chemical Engineering (D.H.), Pohang University of Science and Technology, Pohang, Korea; and Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea (J.L., Y.J.K, G.Y.K.).

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http://atvb.ahajournals.org/content/34/8/1697.full.pdf
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http://atvb.ahajournals.org/cgi/doi/10.1161/ATVBAHA.114.3034
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http://dx.doi.org/10.1161/ATVBAHA.114.303416DOI Listing
August 2014

Intracavernous delivery of stromal vascular fraction restores erectile function through production of angiogenic factors in a mouse model of cavernous nerve injury.

J Sex Med 2014 Aug 5;11(8):1962-73. Epub 2014 Jun 5.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon, Korea.

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http://dx.doi.org/10.1111/jsm.12597DOI Listing
August 2014

Reprogramming of mouse somatic cells into pluripotent stem-like cells using a combination of small molecules.

Biomaterials 2014 Aug 2;35(26):7336-45. Epub 2014 Jun 2.

Laboratory of Cell Function Regulation, Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.05.015DOI Listing
August 2014

Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis.

Circ Res 2014 Jul 22;115(2):215-26. Epub 2014 Apr 22.

From the Graduate School of Medical Science and Engineering (S.-H.L., S.L., H.Y., S.S., K.K., G.Y.K., I.K.) and Biomedical Science and Engineering Interdisciplinary Program (S.-H.L., G.Y.K., I.K.), Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea; Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Hospital, Gwangju, Republic of Korea (S.L.); Transgenic Animal Model Core, University of Michigan, Ann Arbor (T.L.S.); and Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough (J.K.Y.)

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http://dx.doi.org/10.1161/CIRCRESAHA.115.303142DOI Listing
July 2014

Angiopoietin-1 suppresses choroidal neovascularization and vascular leakage.

Invest Ophthalmol Vis Sci 2014 Apr 7;55(4):2191-9. Epub 2014 Apr 7.

National Research Laboratory of Vascular Biology and Stem Cells, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

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http://dx.doi.org/10.1167/iovs.14-13897DOI Listing
April 2014

Vascular RhoJ is an effective and selective target for tumor angiogenesis and vascular disruption.

Cancer Cell 2014 Jan;25(1):102-17

National Research Laboratory of Vascular Biology and Stem Cells, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea; Graduate School of Medical Science and Engineering, KAIST, Daejeon 305-701, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.12.010DOI Listing
January 2014

Interactions of immune cells and lymphatic vessels.

Adv Anat Embryol Cell Biol 2014 ;214:107-18

Laboratory of Vascular Biology and Stem Cells, Graduate School of Biomedical Science and Engineering, Korea Advanced Institute of Science and Technology, 373-1, Guseong-dong, Daejeon, 305-701, South Korea.

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http://dx.doi.org/10.1007/978-3-7091-1646-3_9DOI Listing
April 2014

Reversing the intractable nature of pancreatic cancer by selectively targeting ALDH-high, therapy-resistant cancer cells.

PLoS One 2013 23;8(10):e78130. Epub 2013 Oct 23.

Graduate School of Medical Science and Engineering, South Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078130PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806801PMC
February 2015

TRAIL negatively regulates VEGF-induced angiogenesis via caspase-8-mediated enzymatic and non-enzymatic functions.

Angiogenesis 2014 Jan 5;17(1):179-94. Epub 2013 Oct 5.

Vascular Homeostasis Laboratory and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, 200-701, Korea.

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http://dx.doi.org/10.1007/s10456-013-9387-0DOI Listing
January 2014

Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy.

Sci Transl Med 2013 Sep;5(203):203ra127

National Research Laboratory of Vascular Biology and Stem Cells, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30066
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http://dx.doi.org/10.1126/scitranslmed.3006666DOI Listing
September 2013

Effect of intracavernous administration of angiopoietin-4 on erectile function in the streptozotocin-induced diabetic mouse.

J Sex Med 2013 Dec 12;10(12):2912-27. Epub 2013 Aug 12.

National Research Center for Sexual Medicine and Department of Urology, Inha University School of Medicine, Incheon, Korea.

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http://dx.doi.org/10.1111/jsm.12278DOI Listing
December 2013

VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy.

EMBO Mol Med 2013 Sep 2;5(9):1415-30. Epub 2013 Aug 2.

Laboratory of Vascular Biology and Stem Cells and Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

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http://dx.doi.org/10.1002/emmm.201302618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799495PMC
September 2013

Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes.

Blood 2013 Sep 8;122(13):2151-61. Epub 2013 Jul 8.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea;

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http://dx.doi.org/10.1182/blood-2013-01-478941DOI Listing
September 2013

Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice.

J Clin Invest 2013 Jan 17;123(1):418-31. Epub 2012 Dec 17.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://www.jci.org/articles/view/64547
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533291PMC
January 2013

Orchestral actions of angiopoietin-1 in vascular regeneration.

Authors:
Gou Young Koh

Trends Mol Med 2013 Jan 23;19(1):31-9. Epub 2012 Nov 23.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, South Korea.

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http://dx.doi.org/10.1016/j.molmed.2012.10.010DOI Listing
January 2013

ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells.

Blood 2012 Sep 14;120(13):2733-44. Epub 2012 Aug 14.

Laboratory for Vascular Biology and Stem Cell, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

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http://dx.doi.org/10.1182/blood-2012-04-421610DOI Listing
September 2012

Regulation and implications of inflammatory lymphangiogenesis.

Trends Immunol 2012 Jul 12;33(7):350-6. Epub 2012 May 12.

National Research Laboratory of Vascular Biology and Stem Cells, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

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http://dx.doi.org/10.1016/j.it.2012.03.006DOI Listing
July 2012

Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.

J Cell Sci 2012 May 22;125(Pt 9):2212-23. Epub 2012 Feb 22.

Oulu Center for Cell-Matrix Research, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.098020
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May 2012

Peroxiredoxin II is an essential antioxidant enzyme that prevents the oxidative inactivation of VEGF receptor-2 in vascular endothelial cells.

Mol Cell 2011 Nov;44(4):545-58

Division of Life and Pharmaceutical Science, Center for Cell Signaling and Drug Discovery Research, Ewha Womans University, Seoul 127-750, Korea.

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http://dx.doi.org/10.1016/j.molcel.2011.08.040DOI Listing
November 2011

Ang2, the instigator of inflammation.

Blood 2011 Nov;118(18):4767-8

Korea Advanced Institute Of Science and Technology, Korea.

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http://dx.doi.org/10.1182/blood-2011-09-377333DOI Listing
November 2011

The spatiotemporal development of adipose tissue.

Development 2011 Nov;138(22):5027-37

National Research Laboratory of Vascular Biology and Stem Cells, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea.

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http://dev.biologists.org/cgi/doi/10.1242/dev.067686
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November 2011

Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells.

Blood 2011 Aug 16;118(8):2094-104. Epub 2011 Jun 16.

Laboratory for Vascular Biology and Stem Cell, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

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http://dx.doi.org/10.1182/blood-2010-12-323907DOI Listing
August 2011

Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.

Am J Pathol 2011 Jun 6;178(6):2897-909. Epub 2011 May 6.

Department of Anatomy, Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124300PMC
June 2011

Angptl4 deficiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice.

Biochem Biophys Res Commun 2011 Jun 28;409(2):177-80. Epub 2011 Apr 28.

Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.04.110DOI Listing
June 2011

Effects of culture temperature and pH on flag-tagged COMP angiopoietin-1 (FCA1) production from recombinant CHO cells: FCA1 aggregation.

Appl Microbiol Biotechnol 2011 Jul 21;91(2):305-15. Epub 2011 Apr 21.

Department of Biological Sciences and Graduate School of Nanoscience & Technology (WCU), KAIST, 373-1 Guseong-dong, Yuseong-gu, Daejon 305-701, South Korea.

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http://dx.doi.org/10.1007/s00253-011-3266-7DOI Listing
July 2011

Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer.

Mol Cancer 2011 Apr 11;10:36. Epub 2011 Apr 11.

National Research Laboratory of Vascular Biology and Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Republic of Korea.

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http://dx.doi.org/10.1186/1476-4598-10-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080348PMC
April 2011