Gottfried E Konecny

Gottfried E Konecny

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Gottfried E Konecny

Gottfried E Konecny

Publications by authors named "Gottfried E Konecny"

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Inhibition of PD-1 and VEGF in microsatellite-stable endometrial cancer.

Lancet Oncol 2019 May 25;20(5):612-614. Epub 2019 Mar 25.

Division of Hematology and Oncology, Department of Medicine, and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30079-8DOI Listing
May 2019

Combining PARP and CDK4/6 inhibitors in MYC driven ovarian cancer.

EBioMedicine 2019 May 9;43:9-10. Epub 2019 Apr 9.

Division of Hematology/Oncology, Department of Medicine, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193024
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http://dx.doi.org/10.1016/j.ebiom.2019.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557782PMC
May 2019

Editorial: The potential for precision medicine to improve care and speed the development of new treatments in breast and gynecologic malignancies.

Curr Opin Obstet Gynecol 2019 02;31(1):1-3

Department of Medicine, Hematology and Oncology, UCLA Medical Center, Los Angeles, California, USA.

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http://Insights.ovid.com/crossref?an=00001703-201902000-0000
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http://dx.doi.org/10.1097/GCO.0000000000000509DOI Listing
February 2019

Factors that influence survival in high-grade serous ovarian cancer: A complex relationship between molecular subtype, disease dissemination, and operability.

Gynecol Oncol 2018 08 18;150(2):227-232. Epub 2018 Jun 18.

Department of Obstetrics and Gynecology, Division of Gynecologic Surgery, Mayo Clinic, Rochester, MN, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258183094
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http://dx.doi.org/10.1016/j.ygyno.2018.06.002DOI Listing
August 2018

The target invites a foe: antibody-drug conjugates in gynecologic oncology.

Curr Opin Obstet Gynecol 2018 Feb;30(1):44-50

Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/GCO.0000000000000432DOI Listing
February 2018

Targeting fibroblast growth factor pathways in endometrial cancer.

Curr Probl Cancer 2017 Jan - Feb;41(1):37-47. Epub 2016 Nov 11.

Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.currproblcancer.2016.11.002DOI Listing
December 2017

Intraperitoneal disease dissemination patterns are associated with residual disease, extent of surgery, and molecular subtypes in advanced ovarian cancer.

Gynecol Oncol 2017 12 28;147(3):503-508. Epub 2017 Sep 28.

Department of Obstetrics and Gynecology, Division of Gynecologic Surgery, Mayo Clinic, Rochester, MN, United States; Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698116PMC
December 2017

Understanding Exceptional Responses to Poly (ADP-ribose) Polymerase Inhibition in Sporadic Ovarian Cancer.

J Clin Oncol 2017 04 6;35(11):1151-1153. Epub 2017 Mar 6.

Gottfried E. Konecny, University of California Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1200/JCO.2016.72.0052DOI Listing
April 2017

Cancer genomics and clinical practice: how can we close the gap more quickly?

Curr Opin Obstet Gynecol 2017 02;29(1):1-3

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/GCO.0000000000000341DOI Listing
February 2017

Enhanced skin toxicity with concurrent ipilimumab and radiation in vaginal/vulvar melanoma: a case report and literature review.

BJR Case Rep 2017 29;3(1):20160002. Epub 2016 Jul 29.

Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1259/bjrcr.20160002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159297PMC
July 2016

Gene-expression signatures in ovarian cancer: Promise and challenges for patient stratification.

Gynecol Oncol 2016 05 28;141(2):379-385. Epub 2016 Jan 28.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.ygyno.2016.01.026DOI Listing
May 2016

Molecular classification of high grade endometrioid and clear cell ovarian cancer using TCGA gene expression signatures.

Gynecol Oncol 2016 Apr;141(1):95-100

Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.02.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616158PMC
April 2016

Cyclin-dependent kinase pathways as targets for women's cancer treatment.

Curr Opin Obstet Gynecol 2016 Feb;28(1):42-8

David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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http://jco.ascopubs.org/content/24/11/1770.full.pdf
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http://escholarship.org/uc/item/25w1d4f4.pdf
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/GCO.0000000000000243DOI Listing
February 2016

Securing global access to innovations in women's cancer care and control.

Curr Opin Obstet Gynecol 2016 Feb;28(1):1-3

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/GCO.0000000000000244DOI Listing
February 2016

Beyond genomics: critical evaluation of cell line utility for ovarian cancer research.

Gynecol Oncol 2015 Oct 29;139(1):97-103. Epub 2015 Aug 29.

Dana-Farber Cancer Institute, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2015.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587360PMC
October 2015

Biomarkers in women's cancers, gynecology, and obstetrics.

Biomed Res Int 2014 10;2014:602340. Epub 2014 Jul 10.

Molecular Cancer Epidemiology Laboratory, Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital Post Office, Herston, QLD 4029, Australia.

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http://dx.doi.org/10.1155/2014/602340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120780PMC
September 2015

The path to personalized medicine in women's cancers: challenges and recent advances.

Curr Opin Obstet Gynecol 2015 Feb;27(1):45-7

Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/GCO.0000000000000149DOI Listing
February 2015

Primary results of ROSE/TRIO-12, a randomized placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer.

J Clin Oncol 2015 Jan 2;33(2):141-8. Epub 2014 Sep 2.

John R. Mackey, Cross Cancer Institute; Francois Thireau and Helena Fung, Translational Research in Oncology, Edmonton; Marc Webster, Tom Baker Cancer Centre, Calgary, Alberta; Karen A. Gelmon, British Columbia Cancer Agency, Vancouver, British Columbia; Sunil Verma, Sunnybrook Health Sciences Center; Lorinda Simms, Eli Lilly, Toronto, Ontario, Canada; Manuel Ramos-Vazquez, Centro Oncológico de Galicia "José Antonio Quiroga y Piñeiro," A Coruña; Miguel Martin, Instituto de Investigación Sanitaria Gregorio Marañon, Universidad Complutense, Madrid, Spain; Oleg Lipatov, Republican Clinical Oncology Dispensary, Bashkortostan Republic Ministry of Health, Ufa; Dmitriy Krasnozhon, Leningrad Regional Oncology Dispensary, Leningrad; Vladimir Semiglazov, Institute of Oncology N.N. Petrov; Alexey Manikhas, City Clinical Oncology Dispensary, St Petersburg; Vera Gorbunova, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia; Nicole McCarthy, ICON Cancer Care Wesley, Brisbane, Queensland, Australia; Gottfried E. Konecny, University of California Los Angeles, Los Angeles, CA; Roberto Hegg, Hospital Pérola Byigton Centro de Referência da Saúde da Mulher, Sao Paulo, Brazil; Dany Abi Gerges, Middle East Institute of Health, Bsalim, Lebanon; Marc Buyse, International Drug Development Institute, Louvain-la-Neuve, Belgium; and Ayman Ibrahim, ImClone Systems, Bridgewater, NJ.

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http://dx.doi.org/10.1200/JCO.2014.57.1513DOI Listing
January 2015

Current and future role of neoadjuvant therapy for breast cancer.

Breast 2014 Oct 14;23(5):526-37. Epub 2014 Jul 14.

German Breast Group c/o GBG Forschungs GmbH, Neu Isenburg, Germany; University Women's Hospital, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.breast.2014.06.004DOI Listing
October 2014

Prognostic and therapeutic relevance of molecular subtypes in high-grade serous ovarian cancer.

J Natl Cancer Inst 2014 Oct 30;106(10). Epub 2014 Sep 30.

Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA (GEK, HH, JD, CG, HWC, DJS); Department of Health Sciences Research (CW, ELG), Department of Gynecologic Surgery (BW, SD, WC, BG, KCP), Department of Medicine (KRK, LCH), and Department of Pathology (GK), Mayo Clinic, Rochester, MN; Department of Biostatistics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA (HJW).

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http://dx.doi.org/10.1093/jnci/dju249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271115PMC
October 2014

Ganitumab (AMG 479) inhibits IGF-II-dependent ovarian cancer growth and potentiates platinum-based chemotherapy.

Clin Cancer Res 2014 Jun 11;20(11):2947-58. Epub 2014 Apr 11.

Authors' Affiliations: Oncology Research Therapeutic Area, Genomics Analysis Unit, Department of Pathology, Amgen Inc., Thousand Oaks; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; and The Ludwig Center and the Howard Hughes Medical Institute, Kimmel Cancer Center, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138720PMC
June 2014

Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancer.

Cancer Res 2014 Jun 11;74(11):3084-91. Epub 2014 Apr 11.

Authors' Affiliations: Departments of Health Sciences Research, Medical Oncology, Obstetrics and Gynecology, and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles; Department of Research, Illumina, San Diego, California; Departments of Cancer Biology and Biostatistics, University of Kansas Medical Center, Kansas City, Kansas; and Vaccine and Gene Therapy Institute of Florida, Port St. Lucie, Florida

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054691PMC
June 2014

Sequencing efforts help to refine the molecular classification of breast cancer.

Curr Opin Obstet Gynecol 2014 Feb;26(1):18-20

University of California Los Angeles, Santa Monica, California, USA.

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http://dx.doi.org/10.1097/GCO.0000000000000040DOI Listing
February 2014

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

Authors:
Jennifer Permuth-Wey Kate Lawrenson Howard C Shen Aneliya Velkova Jonathan P Tyrer Zhihua Chen Hui-Yi Lin Y Ann Chen Ya-Yu Tsai Xiaotao Qu Susan J Ramus Rod Karevan Janet Lee Nathan Lee Melissa C Larson Katja K Aben Hoda Anton-Culver Natalia Antonenkova Antonis C Antoniou Sebastian M Armasu François Bacot Laura Baglietto Elisa V Bandera Jill Barnholtz-Sloan Matthias W Beckmann Michael J Birrer Greg Bloom Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Robert Brown Ralf Butzow Qiuyin Cai Ian Campbell Jenny Chang-Claude Stephen Chanock Georgia Chenevix-Trench Jin Q Cheng Mine S Cicek Gerhard A Coetzee Linda S Cook Fergus J Couch Daniel W Cramer Julie M Cunningham Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Douglas F Easton Diana Eccles Robert Edwards Arif B Ekici Peter A Fasching David A Fenstermacher James M Flanagan Montserrat Garcia-Closas Aleksandra Gentry-Maharaj Graham G Giles Rosalind M Glasspool Jesus Gonzalez-Bosquet Marc T Goodman Martin Gore Bohdan Górski Jacek Gronwald Per Hall Mari K Halle Philipp Harter Florian Heitz Peter Hillemanns Maureen Hoatlin Claus K Høgdall Estrid Høgdall Satoyo Hosono Anna Jakubowska Allan Jensen Heather Jim Kimberly R Kalli Beth Y Karlan Stanley B Kaye Linda E Kelemen Lambertus A Kiemeney Fumitaka Kikkawa Gottfried E Konecny Camilla Krakstad Susanne Krüger Kjaer Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Johnathan M Lancaster Nhu D Le Arto Leminen Douglas A Levine Dong Liang Boon Kiong Lim Jie Lin Jolanta Lissowska Karen H Lu Jan Lubiński Galina Lurie Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Usha Menon Francesmary Modugno Kirsten B Moysich Toru Nakanishi Steven A Narod Lotte Nedergaard Roberta B Ness Heli Nevanlinna Stefan Nickels Houtan Noushmehr Kunle Odunsi Sara H Olson Irene Orlow James Paul Celeste L Pearce Tanja Pejovic Liisa M Pelttari Malcolm C Pike Elizabeth M Poole Paola Raska Stefan P Renner Harvey A Risch Lorna Rodriguez-Rodriguez Mary Anne Rossing Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Gianluca Severi Viji Shridhar Xiao-Ou Shu Yurii B Shvetsov Weiva Sieh Honglin Song Melissa C Southey Beata Spiewankiewicz Daniel Stram Rebecca Sutphen Soo-Hwang Teo Kathryn L Terry Daniel C Tessier Pamela J Thompson Shelley S Tworoger Anne M van Altena Ignace Vergote Robert A Vierkant Daniel Vincent Allison F Vitonis Shan Wang-Gohrke Rachel Palmieri Weber Nicolas Wentzensen Alice S Whittemore Elisabeth Wik Lynne R Wilkens Boris Winterhoff Yin Ling Woo Anna H Wu Yong-Bing Xiang Hannah P Yang Wei Zheng Argyrios Ziogas Famida Zulkifli Catherine M Phelan Edwin Iversen Joellen M Schildkraut Andrew Berchuck Brooke L Fridley Ellen L Goode Paul D P Pharoah Alvaro N A Monteiro Thomas A Sellers Simon A Gayther

Nat Commun 2013 ;4:1627

Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida, USA.

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http://dx.doi.org/10.1038/ncomms2613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709460PMC
October 2013

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.

Authors:
Hui Shen Brooke L Fridley Honglin Song Kate Lawrenson Julie M Cunningham Susan J Ramus Mine S Cicek Jonathan Tyrer Douglas Stram Melissa C Larson Martin Köbel Argyrios Ziogas Wei Zheng Hannah P Yang Anna H Wu Eva L Wozniak Yin Ling Woo Boris Winterhoff Elisabeth Wik Alice S Whittemore Nicolas Wentzensen Rachel Palmieri Weber Allison F Vitonis Daniel Vincent Robert A Vierkant Ignace Vergote David Van Den Berg Anne M Van Altena Shelley S Tworoger Pamela J Thompson Daniel C Tessier Kathryn L Terry Soo-Hwang Teo Claire Templeman Daniel O Stram Melissa C Southey Weiva Sieh Nadeem Siddiqui Yurii B Shvetsov Xiao-Ou Shu Viji Shridhar Shan Wang-Gohrke Gianluca Severi Ira Schwaab Helga B Salvesen Iwona K Rzepecka Ingo B Runnebaum Mary Anne Rossing Lorna Rodriguez-Rodriguez Harvey A Risch Stefan P Renner Elizabeth M Poole Malcolm C Pike Catherine M Phelan Liisa M Pelttari Tanja Pejovic James Paul Irene Orlow Siti Zawiah Omar Sara H Olson Kunle Odunsi Stefan Nickels Heli Nevanlinna Roberta B Ness Steven A Narod Toru Nakanishi Kirsten B Moysich Alvaro N A Monteiro Joanna Moes-Sosnowska Francesmary Modugno Usha Menon John R McLaughlin Valerie McGuire Keitaro Matsuo Noor Azmi Mat Adenan Leon F A G Massuger Galina Lurie Lene Lundvall Jan Lubiński Jolanta Lissowska Douglas A Levine Arto Leminen Alice W Lee Nhu D Le Sandrina Lambrechts Diether Lambrechts Jolanta Kupryjanczyk Camilla Krakstad Gottfried E Konecny Susanne Krüger Kjaer Lambertus A Kiemeney Linda E Kelemen Gary L Keeney Beth Y Karlan Rod Karevan Kimberly R Kalli Hiroaki Kajiyama Bu-Tian Ji Allan Jensen Anna Jakubowska Edwin Iversen Satoyo Hosono Claus K Høgdall Estrid Høgdall Maureen Hoatlin Peter Hillemanns Florian Heitz Rebecca Hein Philipp Harter Mari K Halle Per Hall Jacek Gronwald Martin Gore Marc T Goodman Graham G Giles Aleksandra Gentry-Maharaj Montserrat Garcia-Closas James M Flanagan Peter A Fasching Arif B Ekici Robert Edwards Diana Eccles Douglas F Easton Matthias Dürst Andreas du Bois Thilo Dörk Jennifer A Doherty Evelyn Despierre Agnieszka Dansonka-Mieszkowska Cezary Cybulski Daniel W Cramer Linda S Cook Xiaoqing Chen Bridget Charbonneau Jenny Chang-Claude Ian Campbell Ralf Butzow Clareann H Bunker Doerthe Brueggmann Robert Brown Angela Brooks-Wilson Louise A Brinton Natalia Bogdanova Matthew S Block Elizabeth Benjamin Jonathan Beesley Matthias W Beckmann Elisa V Bandera Laura Baglietto François Bacot Sebastian M Armasu Natalia Antonenkova Hoda Anton-Culver Katja K Aben Dong Liang Xifeng Wu Karen Lu Michelle A T Hildebrandt Joellen M Schildkraut Thomas A Sellers David Huntsman Andrew Berchuck Georgia Chenevix-Trench Simon A Gayther Paul D P Pharoah Peter W Laird Ellen L Goode Celeste Leigh Pearce

Nat Commun 2013 ;4:1628

USC Epigenome Center, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1038/ncomms2629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848248PMC
October 2013

Are ABCB1 (P-glycoprotein) polymorphisms clinically relevant in ovarian cancer? - Finally an Answer!

Gynecol Oncol 2013 Oct;131(1):1-2

University of California, Los Angeles, Los Angeles, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2013.09.001DOI Listing
October 2013

Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells.

Mol Cancer Ther 2013 May 26;12(5):632-42. Epub 2013 Feb 26.

Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0999DOI Listing
May 2013

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

Authors:
Paul D P Pharoah Ya-Yu Tsai Susan J Ramus Catherine M Phelan Ellen L Goode Kate Lawrenson Melissa Buckley Brooke L Fridley Jonathan P Tyrer Howard Shen Rachel Weber Rod Karevan Melissa C Larson Honglin Song Daniel C Tessier François Bacot Daniel Vincent Julie M Cunningham Joe Dennis Ed Dicks Katja K Aben Hoda Anton-Culver Natalia Antonenkova Sebastian M Armasu Laura Baglietto Elisa V Bandera Matthias W Beckmann Michael J Birrer Greg Bloom Natalia Bogdanova James D Brenton Louise A Brinton Angela Brooks-Wilson Robert Brown Ralf Butzow Ian Campbell Michael E Carney Renato S Carvalho Jenny Chang-Claude Y Anne Chen Zhihua Chen Wong-Ho Chow Mine S Cicek Gerhard Coetzee Linda S Cook Daniel W Cramer Cezary Cybulski Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Diana Eccles Robert Edwards Arif B Ekici Peter A Fasching David Fenstermacher James Flanagan Yu-Tang Gao Montserrat Garcia-Closas Aleksandra Gentry-Maharaj Graham Giles Anxhela Gjyshi Martin Gore Jacek Gronwald Qi Guo Mari K Halle Philipp Harter Alexander Hein Florian Heitz Peter Hillemanns Maureen Hoatlin Estrid Høgdall Claus K Høgdall Satoyo Hosono Anna Jakubowska Allan Jensen Kimberly R Kalli Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne Krüger Kjaer Gottfried E Konecny Camilla Krakstad Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Nathan Lee Janet Lee Arto Leminen Boon Kiong Lim Jolanta Lissowska Jan Lubiński Lene Lundvall Galina Lurie Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Usha Menon Francesmary Modugno Kirsten B Moysich Toru Nakanishi Steven A Narod Roberta B Ness Heli Nevanlinna Stefan Nickels Houtan Noushmehr Kunle Odunsi Sara Olson Irene Orlow James Paul Tanja Pejovic Liisa M Pelttari Jenny Permuth-Wey Malcolm C Pike Elizabeth M Poole Xiaotao Qu Harvey A Risch Lorna Rodriguez-Rodriguez Mary Anne Rossing Anja Rudolph Ingo Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Gianluca Severi Hui Shen Vijayalakshmi Shridhar Xiao-Ou Shu Weiva Sieh Melissa C Southey Paul Spellman Kazuo Tajima Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Agnieszka Timorek Shelley S Tworoger Anne M van Altena David van den Berg Ignace Vergote Robert A Vierkant Allison F Vitonis Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Elisabeth Wik Boris Winterhoff Yin Ling Woo Anna H Wu Hannah P Yang Wei Zheng Argyrios Ziogas Famida Zulkifli Marc T Goodman Per Hall Douglas F Easton Celeste L Pearce Andrew Berchuck Georgia Chenevix-Trench Edwin Iversen Alvaro N A Monteiro Simon A Gayther Joellen M Schildkraut Thomas A Sellers

Nat Genet 2013 Apr;45(4):362-70, 370e1-2

The Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.2564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693183PMC
April 2013

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

Authors:
Stig E Bojesen Karen A Pooley Sharon E Johnatty Jonathan Beesley Kyriaki Michailidou Jonathan P Tyrer Stacey L Edwards Hilda A Pickett Howard C Shen Chanel E Smart Kristine M Hillman Phuong L Mai Kate Lawrenson Michael D Stutz Yi Lu Rod Karevan Nicholas Woods Rebecca L Johnston Juliet D French Xiaoqing Chen Maren Weischer Sune F Nielsen Melanie J Maranian Maya Ghoussaini Shahana Ahmed Caroline Baynes Manjeet K Bolla Qin Wang Joe Dennis Lesley McGuffog Daniel Barrowdale Andrew Lee Sue Healey Michael Lush Daniel C Tessier Daniel Vincent Françis Bacot Ignace Vergote Sandrina Lambrechts Evelyn Despierre Harvey A Risch Anna González-Neira Mary Anne Rossing Guillermo Pita Jennifer A Doherty Nuria Alvarez Melissa C Larson Brooke L Fridley Nils Schoof Jenny Chang-Claude Mine S Cicek Julian Peto Kimberly R Kalli Annegien Broeks Sebastian M Armasu Marjanka K Schmidt Linde M Braaf Boris Winterhoff Heli Nevanlinna Gottfried E Konecny Diether Lambrechts Lisa Rogmann Pascal Guénel Attila Teoman Roger L Milne Joaquin J Garcia Angela Cox Vijayalakshmi Shridhar Barbara Burwinkel Frederik Marme Rebecca Hein Elinor J Sawyer Christopher A Haiman Shan Wang-Gohrke Irene L Andrulis Kirsten B Moysich John L Hopper Kunle Odunsi Annika Lindblom Graham G Giles Hermann Brenner Jacques Simard Galina Lurie Peter A Fasching Michael E Carney Paolo Radice Lynne R Wilkens Anthony Swerdlow Marc T Goodman Hiltrud Brauch Montserrat Garcia-Closas Peter Hillemanns Robert Winqvist Matthias Dürst Peter Devilee Ingo Runnebaum Anna Jakubowska Jan Lubinski Arto Mannermaa Ralf Butzow Natalia V Bogdanova Thilo Dörk Liisa M Pelttari Wei Zheng Arto Leminen Hoda Anton-Culver Clareann H Bunker Vessela Kristensen Roberta B Ness Kenneth Muir Robert Edwards Alfons Meindl Florian Heitz Keitaro Matsuo Andreas du Bois Anna H Wu Philipp Harter Soo-Hwang Teo Ira Schwaab Xiao-Ou Shu William Blot Satoyo Hosono Daehee Kang Toru Nakanishi Mikael Hartman Yasushi Yatabe Ute Hamann Beth Y Karlan Suleeporn Sangrajrang Susanne Krüger Kjaer Valerie Gaborieau Allan Jensen Diana Eccles Estrid Høgdall Chen-Yang Shen Judith Brown Yin Ling Woo Mitul Shah Mat Adenan Noor Azmi Robert Luben Siti Zawiah Omar Kamila Czene Robert A Vierkant Børge G Nordestgaard Henrik Flyger Celine Vachon Janet E Olson Xianshu Wang Douglas A Levine Anja Rudolph Rachel Palmieri Weber Dieter Flesch-Janys Edwin Iversen Stefan Nickels Joellen M Schildkraut Isabel Dos Santos Silva Daniel W Cramer Lorna Gibson Kathryn L Terry Olivia Fletcher Allison F Vitonis C Ellen van der Schoot Elizabeth M Poole Frans B L Hogervorst Shelley S Tworoger Jianjun Liu Elisa V Bandera Jingmei Li Sara H Olson Keith Humphreys Irene Orlow Carl Blomqvist Lorna Rodriguez-Rodriguez Kristiina Aittomäki Helga B Salvesen Taru A Muranen Elisabeth Wik Barbara Brouwers Camilla Krakstad Els Wauters Mari K Halle Hans Wildiers Lambertus A Kiemeney Claire Mulot Katja K Aben Pierre Laurent-Puig Anne Mvan Altena Thérèse Truong Leon F A G Massuger Javier Benitez Tanja Pejovic Jose Ignacio Arias Perez Maureen Hoatlin M Pilar Zamora Linda S Cook Sabapathy P Balasubramanian Linda E Kelemen Andreas Schneeweiss Nhu D Le Christof Sohn Angela Brooks-Wilson Ian Tomlinson Michael J Kerin Nicola Miller Cezary Cybulski Brian E Henderson Janusz Menkiszak Fredrick Schumacher Nicolas Wentzensen Loic Le Marchand Hannah P Yang Anna Marie Mulligan Gord Glendon Svend Aage Engelholm Julia A Knight Claus K Høgdall Carmel Apicella Martin Gore Helen Tsimiklis Honglin Song Melissa C Southey Agnes Jager Ans M Wvan den Ouweland Robert Brown John W M Martens James M Flanagan Mieke Kriege James Paul Sara Margolin Nadeem Siddiqui Gianluca Severi Alice S Whittemore Laura Baglietto Valerie McGuire Christa Stegmaier Weiva Sieh Heiko Müller Volker Arndt France Labrèche Yu-Tang Gao Mark S Goldberg Gong Yang Martine Dumont John R McLaughlin Arndt Hartmann Arif B Ekici Matthias W Beckmann Catherine M Phelan Michael P Lux Jenny Permuth-Wey Bernard Peissel Thomas A Sellers Filomena Ficarazzi Monica Barile Argyrios Ziogas Alan Ashworth Aleksandra Gentry-Maharaj Michael Jones Susan J Ramus Nick Orr Usha Menon Celeste L Pearce Thomas Brüning Malcolm C Pike Yon-Dschun Ko Jolanta Lissowska Jonine Figueroa Jolanta Kupryjanczyk Stephen J Chanock Agnieszka Dansonka-Mieszkowska Arja Jukkola-Vuorinen Iwona K Rzepecka Katri Pylkäs Mariusz Bidzinski Saila Kauppila Antoinette Hollestelle Caroline Seynaeve Rob A E M Tollenaar Katarzyna Durda Katarzyna Jaworska Jaana M Hartikainen Veli-Matti Kosma Vesa Kataja Natalia N Antonenkova Jirong Long Martha Shrubsole Sandra Deming-Halverson Artitaya Lophatananon Pornthep Siriwanarangsan Sarah Stewart-Brown Nina Ditsch Peter Lichtner Rita K Schmutzler Hidemi Ito Hiroji Iwata Kazuo Tajima Chiu-Chen Tseng Daniel O Stram David van den Berg Cheng Har Yip M Kamran Ikram Yew-Ching Teh Hui Cai Wei Lu Lisa B Signorello Qiuyin Cai Dong-Young Noh Keun-Young Yoo Hui Miao Philip Tsau-Choong Iau Yik Ying Teo James McKay Charles Shapiro Foluso Ademuyiwa George Fountzilas Chia-Ni Hsiung Jyh-Cherng Yu Ming-Feng Hou Catherine S Healey Craig Luccarini Susan Peock Dominique Stoppa-Lyonnet Paolo Peterlongo Timothy R Rebbeck Marion Piedmonte Christian F Singer Eitan Friedman Mads Thomassen Kenneth Offit Thomas V O Hansen Susan L Neuhausen Csilla I Szabo Ignacio Blanco Judy Garber Steven A Narod Jeffrey N Weitzel Marco Montagna Edith Olah Andrew K Godwin Drakoulis Yannoukakos David E Goldgar Trinidad Caldes Evgeny N Imyanitov Laima Tihomirova Banu K Arun Ian Campbell Arjen R Mensenkamp Christi J van Asperen Kees E P van Roozendaal Hanne Meijers-Heijboer J Margriet Collée Jan C Oosterwijk Maartje J Hooning Matti A Rookus Rob B van der Luijt Theo A Mvan Os D Gareth Evans Debra Frost Elena Fineberg Julian Barwell Lisa Walker M John Kennedy Radka Platte Rosemarie Davidson Steve D Ellis Trevor Cole Brigitte Bressac-de Paillerets Bruno Buecher Francesca Damiola Laurence Faivre Marc Frenay Olga M Sinilnikova Olivier Caron Sophie Giraud Sylvie Mazoyer Valérie Bonadona Virginie Caux-Moncoutier Aleksandra Toloczko-Grabarek Jacek Gronwald Tomasz Byrski Amanda B Spurdle Bernardo Bonanni Daniela Zaffaroni Giuseppe Giannini Loris Bernard Riccardo Dolcetti Siranoush Manoukian Norbert Arnold Christoph Engel Helmut Deissler Kerstin Rhiem Dieter Niederacher Hansjoerg Plendl Christian Sutter Barbara Wappenschmidt Ake Borg Beatrice Melin Johanna Rantala Maria Soller Katherine L Nathanson Susan M Domchek Gustavo C Rodriguez Ritu Salani Daphne Gschwantler Kaulich Muy-Kheng Tea Shani Shimon Paluch Yael Laitman Anne-Bine Skytte Torben A Kruse Uffe Birk Jensen Mark Robson Anne-Marie Gerdes Bent Ejlertsen Lenka Foretova Sharon A Savage Jenny Lester Penny Soucy Karoline B Kuchenbaecker Curtis Olswold Julie M Cunningham Susan Slager Vernon S Pankratz Ed Dicks Sunil R Lakhani Fergus J Couch Per Hall Alvaro N A Monteiro Simon A Gayther Paul D P Pharoah Roger R Reddel Ellen L Goode Mark H Greene Douglas F Easton Andrew Berchuck Antonis C Antoniou Georgia Chenevix-Trench Alison M Dunning

Nat Genet 2013 Apr;45(4):371-84, 384e1-2

Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ng.2566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670748PMC
April 2013

Emerging strategies for the dual inhibition of HER2-positive breast cancer.

Curr Opin Obstet Gynecol 2013 Feb;25(1):55-65

David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90404-2429, USA.

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http://dx.doi.org/10.1097/GCO.0b013e32835c5e90DOI Listing
February 2013

Amplification Target ADRM1: Role as an Oncogene and Therapeutic Target for Ovarian Cancer.

Int J Mol Sci 2013 Feb 1;14(2):3094-109. Epub 2013 Feb 1.

Division of Hematology-Oncology, Department of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.3390/ijms14023094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588033PMC
February 2013

Neoadjuvant clinical trials for the treatment of primary breast cancer: the experience of the German study groups.

Curr Oncol Rep 2012 Feb;14(1):27-34

Department of Gynecology, Helios Klinikum Berlin-Buch, Berlin, Germany.

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http://dx.doi.org/10.1007/s11912-011-0212-xDOI Listing
February 2012

Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma.

Clin Cancer Res 2011 Apr 3;17(8):2373-84. Epub 2011 Mar 3.

Division of Gynecologic Oncology, Departments of Obstetrics and Gynecology, UCLA David Geffen School of Medicine, Los Angeles, CA 90095-1740, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078990PMC
April 2011

Association between HER2, TOP2A, and response to anthracycline-based preoperative chemotherapy in high-risk primary breast cancer.

Breast Cancer Res Treat 2010 Apr 4;120(2):481-9. Epub 2010 Feb 4.

UCLA Translational Oncology Research Lab, David Geffen School of Medicine, University of California Los Angeles, 2825 Santa Monica Blvd, Suite 200, Santa Monica, CA, 90404-2429, USA.

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http://dx.doi.org/10.1007/s10549-010-0744-zDOI Listing
April 2010

A new ELISA for use in a 3-ELISA system to assess concentrations of VEGF splice variants and VEGF(110) in ovarian cancer tumors.

Clin Chem 2008 Mar;54(3):597-601

Department of Assay and Automation Technology, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1373/clinchem.2007.096099DOI Listing
March 2008

Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells.

Cancer Res 2006 Feb;66(3):1630-9

Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, 12-145 Factor Building, 10945 Le Conte Avenue, Los Angeles, CA 90095-1678, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1182DOI Listing
February 2006

Gemcitabine in combination with trastuzumab and/or platinum salts in breast cancer cells with HER2 overexpression.

Oncology (Williston Park) 2004 Dec;18(14 Suppl 12):32-6

University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California 90095-1678, USA.

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December 2004

Her-2/neu gene amplification and response to paclitaxel in patients with metastatic breast cancer.

J Natl Cancer Inst 2004 Aug;96(15):1141-51

Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, and Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095-7077, USA.

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http://dx.doi.org/10.1093/jnci/djh198DOI Listing
August 2004

Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer.

J Natl Cancer Inst 2004 May;96(10):739-49

Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles 90095-7077, USA.

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http://dx.doi.org/10.1093/jnci/djh131DOI Listing
May 2004

Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients.

Clin Cancer Res 2004 Mar;10(5):1706-16

Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095-1678, USA.

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March 2004