Publications by authors named "Gordon Wells"

18Publications

The H3ABioNet helpdesk: an online bioinformatics resource, enhancing Africa's capacity for genomics research.

BMC Bioinformatics 2019 Dec 30;20(1):741. Epub 2019 Dec 30.

Computational Biology Division, IDM, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.

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December 2019

Compromised Metabolic Reprogramming Is an Early Indicator of CD8 T Cell Dysfunction during Chronic Mycobacterium tuberculosis Infection.

Cell Rep 2019 12;29(11):3564-3579.e5

Africa Health Research Institute, Durban 4001, South Africa; Department of Microbiology, University of Alabama, Birmingham, AL 35487, USA; Center for AIDS Research (CFAR), University of Alabama, Birmingham, AL 35487, USA; Center for Free Radical Biology (CFRB), University of Alabama, Birmingham, AL 35487, USA. Electronic address:

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December 2019

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.

Cell Rep 2018 11;25(7):1938-1952.e5

Department of Microbiology, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA; Africa Health Research Institute, Durban 4001, South Africa; UAB Center for AIDS Research, The University of Alabama at Birmingham, Birmingham, AL 35294, USA; Center for Free Radical Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:

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November 2018

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.

Am J Hum Genet 2016 Dec 10;99(6):1261-1280. Epub 2016 Nov 10.

Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA; Center for Functional Evaluation of Rare Variants (CFERV), Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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December 2016

Antiviral atropisomers: conformational energy surfaces by NMR for host-directed myxovirus blockers.

J Chem Inf Model 2014 Aug 8;54(8):2214-23. Epub 2014 Aug 8.

School of Chemistry and Physics, University of KwaZulu-Natal , Pietermaritzburg, South Africa.

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August 2014

Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840.

Mol Pharmacol 2014 Apr 22;85(4):618-29. Epub 2014 Jan 22.

Department of Pharmacology (M.A.J., A.J., S.F.T.) and Department of Anesthesiology (A.J.), School of Medicine, and Department of Chemistry (G.W., J.P.S.), Emory University, Atlanta, Georgia; Department of Neuroscience and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.B., R.L.H.); and Department of Molecular Medicine, Cornell University, Ithaca, New York (R.E.O.).

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April 2014

The activity of Plasmodium falciparum arginase is mediated by a novel inter-monomer salt-bridge between Glu295-Arg404.

FEBS J 2009 Jul 18;276(13):3517-30. Epub 2009 May 18.

Department of Biochemistry, University of Pretoria, South Africa.

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July 2009

Novel properties of malarial S-adenosylmethionine decarboxylase as revealed by structural modelling.

J Mol Graph Model 2006 Jan 27;24(4):307-18. Epub 2005 Oct 27.

Department of Biochemistry, School of Biological Sciences, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0002, South Africa.

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January 2006

Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain interactions.

Biochem J 2004 Jan;377(Pt 2):439-48

Department of Biochemistry, School of Biological Sciences, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, 0002, South Africa.

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January 2004