Gordon Lowe

Gordon Lowe

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Gordon Lowe

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Cardiovascular Risk Factors Associated With Venous Thromboembolism.

JAMA Cardiol 2019 02;4(2):163-173

London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.4537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386140PMC
February 2019

The Effect of (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity.

Evid Based Complement Alternat Med 2018 12;2018:4108787. Epub 2018 Jul 12.

School of Preclinic, Institute of Science, Suranaree University of Technology, 111 University Avenue, Suranaree Subdistrict, Muang District, Nakhonratchasima 30000, Thailand.

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https://www.hindawi.com/journals/ecam/2018/4108787/
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http://dx.doi.org/10.1155/2018/4108787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077602PMC
July 2018

Oroxylum indicum (L.) Kurz extract inhibits adipogenesis and lipase activity in vitro.

BMC Complement Altern Med 2018 Jun 8;18(1):177. Epub 2018 Jun 8.

School of Preclinic, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima, 3000, Thailand.

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https://bmccomplementalternmed.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12906-018-2244-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994072PMC
June 2018

Carotenoids-Antioxidant Properties.

Antioxidants (Basel) 2018 Feb 11;7(2). Epub 2018 Feb 11.

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.

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http://dx.doi.org/10.3390/antiox7020028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836018PMC
February 2018

Self-related Health and Blood Hypercoagulability: A Possible Mechanism for Cardiovascular Risk.

Authors:
Gordon D O Lowe

Thromb Haemost 2018 01 5;118(1):4-5. Epub 2018 Jan 5.

Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.

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http://dx.doi.org/10.1160/TH17-11-0836DOI Listing
January 2018

A Possible Indicator of Oxidative Damage in Smokers: (13Z)-Lycopene?

Antioxidants (Basel) 2017 09 13;6(3). Epub 2017 Sep 13.

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.

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http://dx.doi.org/10.3390/antiox6030069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618097PMC
September 2017

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

PLoS One 2017 20;12(1):e0167742. Epub 2017 Jan 20.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167742PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249120PMC
August 2017

Plasma and blood viscosity in the prediction of cardiovascular disease and mortality in the Scottish Heart Health Extended Cohort Study.

Eur J Prev Cardiol 2017 01 17;24(2):161-167. Epub 2016 Oct 17.

2 Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.

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http://dx.doi.org/10.1177/2047487316672004DOI Listing
January 2017

Blood Pressure and Fibrinogen Responses to Mental Stress as Predictors of Incident Hypertension over an 8-Year Period.

Ann Behav Med 2016 12;50(6):898-906

National Centre for Sport & Exercise Medicine, Loughborough University, Loughborough, UK.

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http://dx.doi.org/10.1007/s12160-016-9817-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126198PMC
December 2016

Endothelial Function, Inflammation, Thrombosis, and Basal Ganglia Perivascular Spaces in Patients with Stroke.

J Stroke Cerebrovasc Dis 2016 Dec 27;25(12):2925-2931. Epub 2016 Aug 27.

Division of Neuroimaging Sciences, Centre for Clinical Brain Sciences, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176093PMC
December 2016

The interaction between systemic inflammation and psychosocial stress in the association with cardiac troponin elevation: A new approach to risk assessment and disease prevention.

Prev Med 2016 12 20;93:46-52. Epub 2016 Sep 20.

Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1016/j.ypmed.2016.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126095PMC
December 2016

Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases-A Critical Review.

Crit Rev Food Sci Nutr 2016 Aug;56(11):1868-79

a Institute of Nutrition, Friedrich Schiller University Jena , Jena , Germany.

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http://www.tandfonline.com/doi/full/10.1080/10408398.2013.80
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http://dx.doi.org/10.1080/10408398.2013.801827DOI Listing
August 2016

Aged Garlic Extract Inhibits Human Platelet Aggregation by Altering Intracellular Signaling and Platelet Shape Change.

J Nutr 2016 Feb 13;146(2):410S-415S. Epub 2016 Jan 13.

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

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http://jn.nutrition.org/content/early/2016/01/13/jn.114.2024
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http://jn.nutrition.org/cgi/doi/10.3945/jn.114.202408
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http://dx.doi.org/10.3945/jn.114.202408DOI Listing
February 2016

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Authors:
Tuomas O Kilpeläinen Jayne F Martin Carli Alicja A Skowronski Qi Sun Jennifer Kriebel Mary F Feitosa Åsa K Hedman Alexander W Drong James E Hayes Jinghua Zhao Tune H Pers Ursula Schick Niels Grarup Zoltán Kutalik Stella Trompet Massimo Mangino Kati Kristiansson Marian Beekman Leo-Pekka Lyytikäinen Joel Eriksson Peter Henneman Jari Lahti Toshiko Tanaka Jian'an Luan Fabiola Del Greco M Dorota Pasko Frida Renström Sara M Willems Anubha Mahajan Lynda M Rose Xiuqing Guo Yongmei Liu Marcus E Kleber Louis Pérusse Tom Gaunt Tarunveer S Ahluwalia Yun Ju Sung Yolande F Ramos Najaf Amin Antoinette Amuzu Inês Barroso Claire Bellis John Blangero Brendan M Buckley Stefan Böhringer Yii-Der I Chen Anton J N de Craen David R Crosslin Caroline E Dale Zari Dastani Felix R Day Joris Deelen Graciela E Delgado Ayse Demirkan Francis M Finucane Ian Ford Melissa E Garcia Christian Gieger Stefan Gustafsson Göran Hallmans Susan E Hankinson Aki S Havulinna Christian Herder Dena Hernandez Andrew A Hicks David J Hunter Thomas Illig Erik Ingelsson Andreea Ioan-Facsinay John-Olov Jansson Nancy S Jenny Marit E Jørgensen Torben Jørgensen Magnus Karlsson Wolfgang Koenig Peter Kraft Joanneke Kwekkeboom Tiina Laatikainen Karl-Heinz Ladwig Charles A LeDuc Gordon Lowe Yingchang Lu Pedro Marques-Vidal Christa Meisinger Cristina Menni Andrew P Morris Richard H Myers Satu Männistö Mike A Nalls Lavinia Paternoster Annette Peters Aruna D Pradhan Tuomo Rankinen Laura J Rasmussen-Torvik Wolfgang Rathmann Treva K Rice J Brent Richards Paul M Ridker Naveed Sattar David B Savage Stefan Söderberg Nicholas J Timpson Liesbeth Vandenput Diana van Heemst Hae-Won Uh Marie-Claude Vohl Mark Walker Heinz-Erich Wichmann Elisabeth Widén Andrew R Wood Jie Yao Tanja Zeller Yiying Zhang Ingrid Meulenbelt Margreet Kloppenburg Arne Astrup Thorkild I A Sørensen Mark A Sarzynski D C Rao Pekka Jousilahti Erkki Vartiainen Albert Hofman Fernando Rivadeneira André G Uitterlinden Eero Kajantie Clive Osmond Aarno Palotie Johan G Eriksson Markku Heliövaara Paul B Knekt Seppo Koskinen Antti Jula Markus Perola Risto K Huupponen Jorma S Viikari Mika Kähönen Terho Lehtimäki Olli T Raitakari Dan Mellström Mattias Lorentzon Juan P Casas Stefanie Bandinelli Winfried März Aaron Isaacs Ko W van Dijk Cornelia M van Duijn Tamara B Harris Claude Bouchard Matthew A Allison Daniel I Chasman Claes Ohlsson Lars Lind Robert A Scott Claudia Langenberg Nicholas J Wareham Luigi Ferrucci Timothy M Frayling Peter P Pramstaller Ingrid B Borecki Dawn M Waterworth Sven Bergmann Gérard Waeber Peter Vollenweider Henrik Vestergaard Torben Hansen Oluf Pedersen Frank B Hu P Eline Slagboom Harald Grallert Tim D Spector J W Jukema Robert J Klein Erik E Schadt Paul W Franks Cecilia M Lindgren Rudolph L Leibel Ruth J F Loos

Nat Commun 2016 Feb 1;7:10494. Epub 2016 Feb 1.

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ncomms10494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740377PMC
February 2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

Authors:
Paul S de Vries Daniel I Chasman Maria Sabater-Lleal Ming-Huei Chen Jennifer E Huffman Maristella Steri Weihong Tang Alexander Teumer Riccardo E Marioni Vera Grossmann Jouke J Hottenga Stella Trompet Martina Müller-Nurasyid Jing Hua Zhao Jennifer A Brody Marcus E Kleber Xiuqing Guo Jie Jin Wang Paul L Auer John R Attia Lisa R Yanek Tarunveer S Ahluwalia Jari Lahti Cristina Venturini Toshiko Tanaka Lawrence F Bielak Peter K Joshi Ares Rocanin-Arjo Ivana Kolcic Pau Navarro Lynda M Rose Christopher Oldmeadow Helene Riess Johanna Mazur Saonli Basu Anuj Goel Qiong Yang Mohsen Ghanbari Gonneke Willemsen Ann Rumley Edoardo Fiorillo Anton J M de Craen Anne Grotevendt Robert Scott Kent D Taylor Graciela E Delgado Jie Yao Annette Kifley Charles Kooperberg Rehan Qayyum Lorna M Lopez Tina L Berentzen Katri Räikkönen Massimo Mangino Stefania Bandinelli Patricia A Peyser Sarah Wild David-Alexandre Trégouët Alan F Wright Jonathan Marten Tatijana Zemunik Alanna C Morrison Bengt Sennblad Geoffrey Tofler Moniek P M de Maat Eco J C de Geus Gordon D Lowe Magdalena Zoledziewska Naveed Sattar Harald Binder Uwe Völker Melanie Waldenberger Kay-Tee Khaw Barbara Mcknight Jie Huang Nancy S Jenny Elizabeth G Holliday Lihong Qi Mark G Mcevoy Diane M Becker John M Starr Antti-Pekka Sarin Pirro G Hysi Dena G Hernandez Min A Jhun Harry Campbell Anders Hamsten Fernando Rivadeneira Wendy L Mcardle P Eline Slagboom Tanja Zeller Wolfgang Koenig Bruce M Psaty Talin Haritunians Jingmin Liu Aarno Palotie André G Uitterlinden David J Stott Albert Hofman Oscar H Franco Ozren Polasek Igor Rudan Pierre-Emmanuel Morange James F Wilson Sharon L R Kardia Luigi Ferrucci Tim D Spector Johan G Eriksson Torben Hansen Ian J Deary Lewis C Becker Rodney J Scott Paul Mitchell Winfried März Nick J Wareham Annette Peters Andreas Greinacher Philipp S Wild J Wouter Jukema Dorret I Boomsma Caroline Hayward Francesco Cucca Russell Tracy Hugh Watkins Alex P Reiner Aaron R Folsom Paul M Ridker Christopher J O'Donnell Nicholas L Smith David P Strachan Abbas Dehghan

Hum Mol Genet 2016 Jan 10;25(2):358-70. Epub 2015 Nov 10.

Department of Epidemiology,

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http://hmg.oxfordjournals.org/content/early/2015/12/08/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715256PMC
January 2016

Lifecourse social position and D-dimer; findings from the 1958 British birth cohort.

PLoS One 2014 8;9(5):e93277. Epub 2014 May 8.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, Glasgow, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093277PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014469PMC
October 2015

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

Authors:
Jens Baumert Jie Huang Barbara McKnight Maria Sabater-Lleal Maristella Steri Audrey Y Chu Stella Trompet Lorna M Lopez Myriam Fornage Alexander Teumer Weihong Tang Alicja R Rudnicka Anders Mälarstig Jouke-Jan Hottenga Maryam Kavousi Jari Lahti Toshiko Tanaka Caroline Hayward Jennifer E Huffman Pierre-Emmanuel Morange Lynda M Rose Saonli Basu Ann Rumley David J Stott Brendan M Buckley Anton J M de Craen Serena Sanna Marco Masala Reiner Biffar Georg Homuth Angela Silveira Bengt Sennblad Anuj Goel Hugh Watkins Martina Müller-Nurasyid Regina Rückerl Kent Taylor Ming-Huei Chen Eco J C de Geus Albert Hofman Jacqueline C M Witteman Moniek P M de Maat Aarno Palotie Gail Davies David S Siscovick Ivana Kolcic Sarah H Wild Jaejoon Song Wendy L McArdle Ian Ford Naveed Sattar David Schlessinger Anne Grotevendt Maria Grazia Franzosi Thomas Illig Melanie Waldenberger Thomas Lumley Geoffrey H Tofler Gonneke Willemsen André G Uitterlinden Fernando Rivadeneira Katri Räikkönen Daniel I Chasman Aaron R Folsom Gordon D Lowe Rudi G J Westendorp P Eline Slagboom Francesco Cucca Henri Wallaschofski Rona J Strawbridge Udo Seedorf Wolfgang Koenig Joshua C Bis Kenneth J Mukamal Jenny van Dongen Elisabeth Widen Oscar H Franco John M Starr Kiang Liu Luigi Ferrucci Ozren Polasek James F Wilson Tiphaine Oudot-Mellakh Harry Campbell Pau Navarro Stefania Bandinelli Johan Eriksson Dorret I Boomsma Abbas Dehghan Robert Clarke Anders Hamsten Eric Boerwinkle J Wouter Jukema Silvia Naitza Paul M Ridker Henry Völzke Ian J Deary Alexander P Reiner David-Alexandre Trégouët Christopher J O'Donnell David P Strachan Annette Peters Nicholas L Smith

PLoS One 2014 31;9(12):e111156. Epub 2014 Dec 31.

Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland; Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America; Seattle Epidemiologic Research & Information Center, Veterans Affairs Office of Research & Development, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111156PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281156PMC
September 2015

The association between fibrinogen reactivity to mental stress and high-sensitivity cardiac troponin T in healthy adults.

Psychoneuroendocrinology 2015 Sep 14;59:37-48. Epub 2015 May 14.

Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1016/j.psyneuen.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512259PMC
September 2015

Associations Between Thrombin Generation and the Risk of Cardiovascular Disease in Elderly Patients: Results From the PROSPER Study.

J Gerontol A Biol Sci Med Sci 2015 Aug 24;70(8):982-8. Epub 2014 Dec 24.

Faculty of Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK.

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http://dx.doi.org/10.1093/gerona/glu228DOI Listing
August 2015

Long-term adherence to healthy dietary guidelines and chronic inflammation in the prospective Whitehall II study.

Am J Med 2015 Feb 7;128(2):152-160.e4. Epub 2014 Oct 7.

Department of Epidemiology and Public Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.amjmed.2014.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315808PMC
February 2015

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Authors:
Daniel I Swerdlow David Preiss Karoline B Kuchenbaecker Michael V Holmes Jorgen E L Engmann Tina Shah Reecha Sofat Stefan Stender Paul C D Johnson Robert A Scott Maarten Leusink Niek Verweij Stephen J Sharp Yiran Guo Claudia Giambartolomei Christina Chung Anne Peasey Antoinette Amuzu KaWah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos Yun R Li Gordon Lowe John Gallacher Marlene C W Stewart Ioanna Tzoulaki Sarah G Buxbaum Daphne L van der A Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Urszula Stepaniak Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Fabrizio Veglia Ian Ford J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Pim A de Jong Ale Algra Wilko Spiering Anke H Maitland-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Charles B Eaton Jennifer G Robinson David Duggan John Kjekshus John R Downs Antonio M Gotto Anthony C Keech Roberto Marchioli Gianni Tognoni Peter S Sever Neil R Poulter David D Waters Terje R Pedersen Pierre Amarenco Haruo Nakamura John J V McMurray James D Lewsey Daniel I Chasman Paul M Ridker Aldo P Maggioni Luigi Tavazzi Kausik K Ray Sreenivasa Rao Kondapally Seshasai JoAnn E Manson Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Pamela J Schreiner Myriam Fornage David S Siscovick Mary Cushman Meena Kumari Nick J Wareham W M Monique Verschuren Susan Redline Sanjay R Patel John C Whittaker Anders Hamsten Joseph A Delaney Caroline Dale Tom R Gaunt Andrew Wong Diana Kuh Rebecca Hardy Sekar Kathiresan Berta A Castillo Pim van der Harst Eric J Brunner Anne Tybjaerg-Hansen Michael G Marmot Ronald M Krauss Michael Tsai Josef Coresh Ronald C Hoogeveen Bruce M Psaty Leslie A Lange Hakon Hakonarson Frank Dudbridge Steve E Humphries Philippa J Talmud Mika Kivimäki Nicholas J Timpson Claudia Langenberg Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Alex P Reiner Brendan J Keating Aroon D Hingorani Naveed Sattar

Lancet 2015 Jan 24;385(9965):351-61. Epub 2014 Sep 24.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1016/S0140-6736(14)61183-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322187PMC
January 2015

The relevance of coagulation in cardiovascular disease: what do the biomarkers tell us?

Thromb Haemost 2014 Nov 18;112(5):860-7. Epub 2014 Sep 18.

Gordon Lowe, Institute of Cardiovascular and Medical Sciences, University of Glasgow, New Lister Building, Royal Infirmary, 10-16 Alexandra Parade, Glasgow G31 2ER, UK, Tel.: +44 141 211 4953, E-mail:

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http://dx.doi.org/10.1160/TH14-03-0199DOI Listing
November 2014

Coagulation proteases and cardiovascular disease.

Thromb Haemost 2014 Nov 2;112(5):858-9. Epub 2014 Oct 2.

Hugo ten Cate, University Medical Center - UNS 50/box 8, POBox 616 6200MD Maastricht, Maastricht, Limburg 6200 MD, The Netherlands, E-mail:

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http://dx.doi.org/10.1160/TH14-09-0781DOI Listing
November 2014

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Authors:
Jie Huang Jennifer E Huffman Munekazu Yamakuchi Munekazu Yamkauchi Stella Trompet Folkert W Asselbergs Maria Sabater-Lleal David-Alexandre Trégouët Wei-Min Chen Nicholas L Smith Marcus E Kleber So-Youn Shin Diane M Becker Weihong Tang Abbas Dehghan Andrew D Johnson Vinh Truong Lasse Folkersen Qiong Yang Tiphaine Oudot-Mellkah Brendan M Buckley Jason H Moore Frances M K Williams Harry Campbell Günther Silbernagel Veronique Vitart Igor Rudan Geoffrey H Tofler Gerjan J Navis Anita Destefano Alan F Wright Ming-Huei Chen Anton J M de Craen Bradford B Worrall Alicja R Rudnicka Ann Rumley Ebony B Bookman Bruce M Psaty Fang Chen Keith L Keene Oscar H Franco Bernhard O Böhm Andre G Uitterlinden Angela M Carter J Wouter Jukema Naveed Sattar Joshua C Bis Mohammad A Ikram Michèle M Sale Barbara McKnight Myriam Fornage Ian Ford Kent Taylor P Eline Slagboom Wendy L McArdle Fang-Chi Hsu Anders Franco-Cereceda Alison H Goodall Lisa R Yanek Karen L Furie Mary Cushman Albert Hofman Jacqueline C M Witteman Aaron R Folsom Saonli Basu Nena Matijevic Wiek H van Gilst James F Wilson Rudi G J Westendorp Sekar Kathiresan Muredach P Reilly Russell P Tracy Ozren Polasek Bernhard R Winkelmann Peter J Grant Hans L Hillege Francois Cambien David J Stott Gordon D Lowe Timothy D Spector James B Meigs Winfried Marz Per Eriksson Lewis C Becker Pierre-Emmanuel Morange Nicole Soranzo Scott M Williams Caroline Hayward Pim van der Harst Anders Hamsten Charles J Lowenstein David P Strachan Christopher J O'Donnell

Arterioscler Thromb Vasc Biol 2014 May 27;34(5):1093-101. Epub 2014 Feb 27.

From National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (J.H., A.D.J., C.J.O.); Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, MD (J.H., A.D.J., C.J.O.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom (J.E.H., V.V., A.F.W., C.H.); The Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY (M.Y., C.J.L.); Departments of Cardiology (S.T., J.W.J.), Gerontology and Geriatrics (S.T., A.J.M.d.C., R.G.J.W.), and Molecular Epidemiology (P.E.S.), Leiden University Medical Center, the Netherlands; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (F.W.A.); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands (F.W.A.); Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom (F.W.A.); Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine (M.S.-L., L.F., P.E., A.H.), Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden; INSERM UMRS 937, Pierre et Marie Curie University, Paris, France (D.-A.T., V.T., T.O.M., F.C.); ICAN Institute for Cardiometabolism and Nutrion, Paris, France (D.-A.T., V.T., F.C.); Departments of Public Health Sciences (W.M.C., B.B.W., F.C.) and Biochemistry and Molecular Genetics (M.M.S.), Center for Public Health Genomics, University of Virginia, Charlottesville, VA; Departments of Epidemiology (N.L.S., B.M.P., B.M.), Medicine (B.M.P., J.C.B.), and Health Services (B.M.P.), University of Washington, Seattle, WA; Group Health Research Institute, Group Health Cooperative, Seattle, WA (N.L.S., B.M.P.); Seattle Epidemiologic Research and Information Center, VA Office of Research and

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http://dx.doi.org/10.1161/ATVBAHA.113.302088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009733PMC
May 2014

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis.

Eur Heart J 2014 Mar 10;35(9):578-89. Epub 2013 Sep 10.

Strangeways Research Laboratory, Department of Public Health and Primary Care, University of Cambridge, Worts Causeway, CB1 8RN Cambridge, UK.

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http://dx.doi.org/10.1093/eurheartj/eht367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938862PMC
March 2014

Thrombin generation in the Glasgow Myocardial Infarction Study.

PLoS One 2013 24;8(6):e66977. Epub 2013 Jun 24.

Laboratory of Clinical Thrombosis and Haemostasis, Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066977PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691168PMC
February 2014

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thromb Haemost 2013 Nov 29;110(5):995-1003. Epub 2013 Aug 29.

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1160/TH13-02-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067543PMC
November 2013

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Authors:
Maria Sabater-Lleal Jie Huang Daniel Chasman Silvia Naitza Abbas Dehghan Andrew D Johnson Alexander Teumer Alex P Reiner Lasse Folkersen Saonli Basu Alicja R Rudnicka Stella Trompet Anders Mälarstig Jens Baumert Joshua C Bis Xiuqing Guo Jouke J Hottenga So-Youn Shin Lorna M Lopez Jari Lahti Toshiko Tanaka Lisa R Yanek Tiphaine Oudot-Mellakh James F Wilson Pau Navarro Jennifer E Huffman Tatijana Zemunik Susan Redline Reena Mehra Drazen Pulanic Igor Rudan Alan F Wright Ivana Kolcic Ozren Polasek Sarah H Wild Harry Campbell J David Curb Robert Wallace Simin Liu Charles B Eaton Diane M Becker Lewis C Becker Stefania Bandinelli Katri Räikkönen Elisabeth Widen Aarno Palotie Myriam Fornage David Green Myron Gross Gail Davies Sarah E Harris David C Liewald John M Starr Frances M K Williams Peter J Grant Timothy D Spector Rona J Strawbridge Angela Silveira Bengt Sennblad Fernando Rivadeneira Andre G Uitterlinden Oscar H Franco Albert Hofman Jenny van Dongen Gonneke Willemsen Dorret I Boomsma Jie Yao Nancy Swords Jenny Talin Haritunians Barbara McKnight Thomas Lumley Kent D Taylor Jerome I Rotter Bruce M Psaty Annette Peters Christian Gieger Thomas Illig Anne Grotevendt Georg Homuth Henry Völzke Thomas Kocher Anuj Goel Maria Grazia Franzosi Udo Seedorf Robert Clarke Maristella Steri Kirill V Tarasov Serena Sanna David Schlessinger David J Stott Naveed Sattar Brendan M Buckley Ann Rumley Gordon D Lowe Wendy L McArdle Ming-Huei Chen Geoffrey H Tofler Jaejoon Song Eric Boerwinkle Aaron R Folsom Lynda M Rose Anders Franco-Cereceda Martina Teichert M Arfan Ikram Thomas H Mosley Steve Bevan Martin Dichgans Peter M Rothwell Cathie L M Sudlow Jemma C Hopewell John C Chambers Danish Saleheen Jaspal S Kooner John Danesh Christopher P Nelson Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Pierre-Emmanuel Morange Luigi Ferrucci Johan G Eriksson David Jacobs Ian J Deary Nicole Soranzo Jacqueline C M Witteman Eco J C de Geus Russell P Tracy Caroline Hayward Wolfgang Koenig Francesco Cucca J Wouter Jukema Per Eriksson Sudha Seshadri Hugh S Markus Hugh Watkins Nilesh J Samani Henri Wallaschofski Nicholas L Smith David Tregouet Paul M Ridker Weihong Tang David P Strachan Anders Hamsten Christopher J O'Donnell

Circulation 2013 Sep 22;128(12):1310-24. Epub 2013 Aug 22.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842025PMC
September 2013

A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array.

Eur J Hum Genet 2013 Jul 28;21(7):779-83. Epub 2012 Nov 28.

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield Grove, Bristol, UK.

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http://dx.doi.org/10.1038/ejhg.2012.242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682876PMC
July 2013

Aged garlic extract inhibits platelet activation by increasing intracellular cAMP and reducing the interaction of GPIIb/IIIa receptor with fibrinogen.

Life Sci 2012 Dec 13;91(25-26):1275-80. Epub 2012 Oct 13.

School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, Eric Williams Medical Sciences Complex, Champ Fleurs, Trinidad and Tobago.

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http://dx.doi.org/10.1016/j.lfs.2012.09.019DOI Listing
December 2012

C-reactive protein, fibrinogen, and cardiovascular disease prediction.

N Engl J Med 2012 Oct;367(14):1310-20

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http://dx.doi.org/10.1056/NEJMoa1107477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714101PMC
October 2012

Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease?

Eur Heart J 2012 Sep 5;33(18):2258-64. Epub 2012 Jul 5.

Genetic Epidemiology Group, Research Department of Epidemiology and Public Health, Division of Population Health, University College London, Torrington Place, London WC1E 6BT, UK.

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http://dx.doi.org/10.1093/eurheartj/ehs168DOI Listing
September 2012

(13Z)- and (9Z)-lycopene isomers are major intermediates in the oxidative degradation of lycopene by cigarette smoke and Sin-1.

Free Radic Res 2012 Jul 10;46(7):891-902. Epub 2012 May 10.

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.

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http://dx.doi.org/10.3109/10715762.2012.686663DOI Listing
July 2012

Fibrin D-dimer, tissue-type plasminogen activator, von Willebrand factor, and risk of incident stroke in older men.

Stroke 2012 May 1;43(5):1206-11. Epub 2012 Mar 1.

Department Primary Care and Population Health, UCL Medical School, London NW32PF, UK.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.111.636373
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May 2012

Glucocorticoid treatment and impaired mood, memory and metabolism in people with diabetes: the Edinburgh Type 2 Diabetes Study.

Eur J Endocrinol 2012 May 9;166(5):861-8. Epub 2012 Mar 9.

Endocrinology Unit, University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1530/EJE-12-0041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341665PMC
May 2012

A stitch in time may save nine! Know the ins and outs of workers' comp.

Authors:
T Gordon Lowe

Tenn Med 2012 Apr;105(4):41

Property & Casualty Department, TMA Association Insurance Agency, Inc., P.O. Box 1109, Chattanooga, TN 37404, USA.

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April 2012

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:
Daniel I Swerdlow Michael V Holmes Karoline B Kuchenbaecker Jorgen E L Engmann Tina Shah Reecha Sofat Yiran Guo Christina Chung Anne Peasey Roman Pfister Simon P Mooijaart Helen A Ireland Maarten Leusink Claudia Langenberg Ka Wah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos John Hardy Michael A Nalls Yun Rose Li Gordon Lowe Marlene Stewart Suzette J Bielinski Julian Peto Nicholas J Timpson John Gallacher Malcolm Dunlop Richard Houlston Ian Tomlinson Ioanna Tzoulaki Jian'an Luan Jolanda M A Boer Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Luigi Ferrucci Stefania Bandenelli Toshiko Tanaka James F Meschia Andrew Singleton Gerjan Navis Irene Mateo Leach Stephan J L Bakker Ron T Gansevoort Ian Ford Stephen E Epstein Mary Susan Burnett Joe M Devaney J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Yolanda van der Graaf Pim A de Jong Anke-Hilse Mailand-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Jeffrey W Stephens Charles B Eaton Jennifer G Robinson JoAnn E Manson F Gerry Fowkes Timonthy M Frayling Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Susan Redline Leslie A Lange Meena Kumari Nick J Wareham W M Monique Verschuren Emelia J Benjamin John C Whittaker Anders Hamsten Frank Dudbridge J A Chris Delaney Andrew Wong Diana Kuh Rebecca Hardy Berta Almoguera Castillo John J Connolly Pim van der Harst Eric J Brunner Michael G Marmot Christina L Wassel Steve E Humphries Philippa J Talmud Mika Kivimaki Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Hakon Hakonarson Alex P Reiner Brendan J Keating Naveed Sattar Aroon D Hingorani Juan Pablo Casas

Lancet 2012 Mar 14;379(9822):1214-24. Epub 2012 Mar 14.

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http://dx.doi.org/10.1016/S0140-6736(12)60110-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316968PMC
March 2012

Does lycopene offer human LDL any protection against myeloperoxidase activity?

Mol Cell Biochem 2012 Feb 11;361(1-2):181-7. Epub 2011 Oct 11.

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.

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http://dx.doi.org/10.1007/s11010-011-1102-0DOI Listing
February 2012

Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study.

Cerebrovasc Dis 2011 19;32(2):141-7. Epub 2011 Jul 19.

Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, UK. william.whiteley @ ed.ac.uk

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http://dx.doi.org/10.1159/000328517DOI Listing
January 2012

The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke.

Stroke 2012 Jan 20;43(1):86-91. Epub 2011 Oct 20.

Division of Clinical Neurosciences, General Hospital, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1161/STROKEAHA.111.634089DOI Listing
January 2012

Can haemostatic factors predict atherothrombosis?

Authors:
Gordon Lowe

Intern Emerg Med 2011 Dec 15;6(6):497-501. Epub 2011 Feb 15.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, BHF GCRC, 126 University Place, Glasgow G12 8TA, UK.

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http://link.springer.com/10.1007/s11739-011-0536-4
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December 2011

Childhood intelligence and midlife inflammatory and hemostatic biomarkers: the National Child Development Study (1958) cohort.

Health Psychol 2011 Nov 23;30(6):710-8. Epub 2011 May 23.

Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Glasgow, Scotland.

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http://doi.apa.org/getdoi.cfm?doi=10.1037/a0023940
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November 2011

Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts.

Behav Genet 2011 Sep 23;41(5):691-9. Epub 2011 Jan 23.

Centre for Population Health Sciences, The University of Edinburgh, Medical School, Teviot Place, Edinburgh EH8 9AG, Scotland, UK.

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http://dx.doi.org/10.1007/s10519-011-9449-2DOI Listing
September 2011

N-terminal pro-brain natriuretic Peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease.

J Am Coll Cardiol 2011 Jun;58(1):56-64

Department of Primary Care and Population Health, UCL Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2011.02.041DOI Listing
June 2011

The association between blood coagulation activity and lung function: a population-based study.

PLoS One 2010 Nov 16;5(11):e15014. Epub 2010 Nov 16.

Respiratory Biomedical Research Unit, Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015014PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982817PMC
November 2010

Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation.

Diabetes Care 2010 Sep 2;33(9):1990-6. Epub 2010 Jun 2.

Department of Primary Care and Population Health, University College Medical School, London, U.K.

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http://dx.doi.org/10.2337/dc10-0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928349PMC
September 2010

An analysis of prospective risk factors for aortic stiffness in men: 20-year follow-up from the Caerphilly prospective study.

Hypertension 2010 Jul 7;56(1):36-43. Epub 2010 Jun 7.

Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital, Box 110, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.150896DOI Listing
July 2010

Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study.

Age Ageing 2010 May 2;39(3):354-9. Epub 2010 Mar 2.

Centre for Population Health Sciences, University of Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1093/ageing/afq021DOI Listing
May 2010

Fibrinogen assays for cardiovascular risk assessment.

Authors:
Gordon D O Lowe

Clin Chem 2010 May 26;56(5):693-5. Epub 2010 Mar 26.

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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2010.145342
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May 2010

Venous thrombosis prevention - more than just guidelines.

Br J Haematol 2010 Apr 8;149(1):50-4. Epub 2010 Feb 8.

Department of Transfusion Medicine, Ninewells Hospital, Dundee, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08080.xDOI Listing
April 2010

Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.

Am J Hum Genet 2010 Apr 18;86(4):626-31. Epub 2010 Mar 18.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.ajhg.2010.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850435PMC
April 2010

Is sticky blood bad for the brain?: Hemostatic and inflammatory systems and dementia in the Caerphilly Prospective Study.

Arterioscler Thromb Vasc Biol 2010 Mar 3;30(3):599-604. Epub 2009 Dec 3.

Department of Epidemiology, Statistics and Public Health, Centre for Health Sciences Research, Heath Park, Cardiff CF14 4XN, Wales, England.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.109.197368
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March 2010

Activation of hemostasis and decline in cognitive function in older people.

Arterioscler Thromb Vasc Biol 2010 Mar 23;30(3):605-11. Epub 2009 Dec 23.

Academic Section of Geriatric Medicine, 3 Floor Queen Elizabeth Building, Royal Infirmary, Glasgow G31 2ER.

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http://dx.doi.org/10.1161/ATVBAHA.109.199448DOI Listing
March 2010

What is the clinical relevance of the prothrombin G20210A mutation?

Authors:
Gordon Lowe

Atherosclerosis 2010 Feb 1;208(2):330-1. Epub 2009 Dec 1.

Div of Cardiovascular and Med Sciences, University of Glasgow, Royal Infirmary, Glasgow G4 0SF, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.11.002DOI Listing
February 2010

Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples.

Behav Genet 2010 Jan 10;40(1):3-11. Epub 2009 Oct 10.

Public Health Sciences Section, Division of Community Health Sciences, Centre for Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, EH8 9AG Edinburgh, Scotland, UK.

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http://link.springer.com/10.1007/s10519-009-9302-z
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January 2010

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.

Lancet 2010 Jan 22;375(9709):132-40. Epub 2009 Dec 22.

Emerging Risk Factors Collaboration Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1016/S0140-6736(09)61717-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162187PMC
January 2010

Peripheral levels of fibrinogen, C-reactive protein, and plasma viscosity predict future cognitive decline in individuals without dementia.

Psychosom Med 2009 Oct 6;71(8):901-6. Epub 2009 Aug 6.

Centre for Population Health Sciences, Public Health Sciences Section, University of Edinburgh, Edinburgh, EH8 9AG, Scotland, UK.

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http://dx.doi.org/10.1097/PSY.0b013e3181b1e538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762963PMC
October 2009

Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6.

PLoS Med 2009 Sep 8;6(9):e1000145. Epub 2009 Sep 8.

Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1000145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730573PMC
September 2009