Gordon H Williams

Gordon H Williams

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Genetics of Human Primary Hypertension: Focus on Hormonal Mechanisms.

Endocr Rev 2019 Jun;40(3):825-856

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1210/er.2018-00071DOI Listing
June 2019

Higher urinary cortisol levels associate with increased cardiovascular risk.

Endocr Connect 2019 Jun;8(6):634-640

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1530/EC-19-0182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528405PMC
June 2019

Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice.

Endocrinology 2019 Apr;160(4):716-728

Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1210/en.2018-00989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397424PMC
April 2019

Inner ear pathologies impair sodium-regulated ion transport in Meniere's disease.

Acta Neuropathol 2019 Feb 2;137(2):343-357. Epub 2018 Nov 2.

Otopathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00401-018-1927-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513907PMC
February 2019

Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production.

J Endocrinol 2019 Feb;240(2):111-122

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1530/JOE-18-0247DOI Listing
February 2019

Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice.

Metabolism 2018 06 2;83:92-101. Epub 2018 Feb 2.

Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2018.01.012DOI Listing
June 2018

Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II.

Hypertension 2018 06 23;71(6):1083-1090. Epub 2018 Apr 23.

From the Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital (M.Z.S., J.W.T., W.M., L.H.P., J.S.W., E.W.S., G.K.A., G.H.W., J.R.R.)

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.11087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086591PMC
June 2018

Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants.

JCI Insight 2017 12 7;2(23). Epub 2017 Dec 7.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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https://insight.jci.org/articles/view/95992
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http://dx.doi.org/10.1172/jci.insight.95992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752283PMC
December 2017

Age-Related Autonomous Aldosteronism.

Circulation 2017 Jul 31;136(4):347-355. Epub 2017 May 31.

From Departments of Molecular and Integrative Physiology & Internal Medicine, University of Michigan, Ann Arbor (K.N., I.Z., W.E.R.); Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (A.V., G.H.W.); and Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor (T.E., W.E.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568806PMC
July 2017

Renin Phenotypes Characterize Vascular Disease, Autonomous Aldosteronism, and Mineralocorticoid Receptor Activity.

J Clin Endocrinol Metab 2017 06;102(6):1835-1843

Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-3867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470762PMC
June 2017

Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling.

J Endocrinol 2017 03 17;232(3):525-534. Epub 2017 Jan 17.

Division of EndocrinologyDiabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts, USA

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http://dx.doi.org/10.1530/JOE-16-0452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464000PMC
March 2017

Treatment with patiromer decreases aldosterone in patients with chronic kidney disease and hyperkalemia on renin-angiotensin system inhibitors.

Kidney Int 2016 09 24;90(3):696-704. Epub 2016 Jun 24.

Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.kint.2016.04.019DOI Listing
September 2016

Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis.

J Am Heart Assoc 2016 09 28;5(10). Epub 2016 Sep 28.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1161/JAHA.116.003845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121487PMC
September 2016

Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.

Circulation 2015 Nov 2;132(19):1825-33. Epub 2015 Oct 2.

From Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (R.B., L.H.P., A.V., A.E.G., T.M.Y., J.W., G.K.A., G.H.W.); Department of Endocrinology, School Of Medicine, Pontificia Universidad Catolica De Chile, Santiago, Chile (R.B.); Hospital Clinico, Facultad Medicina Universidad de Chile, Santiago, Chile and Tufts Medical Center, Tufts University School of Medicine, Boston, MA (P.A.V.); Centre Investigation Clinique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Universite Paris Descartes, Paris, France (X.J.); and Cardiovascular Genetics Research, University of Utah School of Medicine Salt Lake City (P.N.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641753PMC
November 2015

Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury.

J Pharmacol Exp Ther 2015 Oct 16;355(1):32-47. Epub 2015 Jul 16.

Cardiovascular Endocrinology Section, Endocrinology, Diabetes, and Hypertension Division (L.H.P., T.M.Y., G.K.A., G.H.W.), and Division of Vascular and Endovascular Surgery (L.A.O., W.T.S., O.M.R., R.A.K.), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

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http://jpet.aspetjournals.org/content/355/1/32.full.pdf
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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.115.22604
Publisher Site
http://dx.doi.org/10.1124/jpet.115.226043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576669PMC
October 2015

Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake.

Hypertension 2015 Sep 13;66(3):674-80. Epub 2015 Jul 13.

From the Cardiovascular Endocrine Section, Division of Endocrinology, Diabetes and Hypertension (A.E.G., L.H.P., B.M., W.M.H., G.K.A., G.H.W.), and Division of Vascular Surgery (L.A.O., W.T.S., M.H., R.A.K.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537321PMC
September 2015

Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans.

Hypertension 2015 Jan 3;65(1):211-217. Epub 2014 Nov 3.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617687PMC
January 2015

Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function.

Endocrinology 2014 Nov 22;155(11):4461-72. Epub 2014 Jul 22.

Molecular Cardiology Research Institute (K.B.M., Q.L., N.N.M., V.L., A.M., R.H.K., I.Z.J.), Tufts Medical Center, and Sackler School of Biomedical Graduate Studies (K.B.M., R.H.K., I.Z.J.), Tufts University School of Medicine, Boston, Massachusetts 02111; and Division of Endocrinology, Diabetes, and Hypertension (G.H.W., G.K.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/en.2014-1270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197987PMC
November 2014

Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk.

Hypertension 2014 Jun 24;63(6):1205-11. Epub 2014 Mar 24.

MMSc, Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, RFB, Boston, MA 02115.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016103PMC
June 2014

Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.

Hypertension 2014 Feb 4;63(2):273-80. Epub 2013 Nov 4.

Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, RFB, Boston, MA 02115.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898197PMC
February 2014

Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice.

J Pharmacol Exp Ther 2014 Feb 26;348(2):260-70. Epub 2013 Nov 26.

Cardiovascular Endocrine Section, Endocrinology, Diabetes and Hypertension Division (L.H.P., T.M.Y., A.E.G., G.K.A., G.H.W.), and Division of Vascular and Endovascular Surgery (L.A.O., O.M.R., R.A.K.), Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.113.20918
Publisher Site
http://dx.doi.org/10.1124/jpet.113.209189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912545PMC
February 2014

Statins and musculoskeletal adverse events.

JAMA Intern Med 2014 Feb;174(2):302-3

Department of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2013.12705DOI Listing
February 2014

Aldosterone's mechanism of action: roles of lysine-specific demethylase 1, caveolin and striatin.

Curr Opin Nephrol Hypertens 2014 Jan;23(1):32-7

aDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. Boston, Massachusetts, USA bDepartment of Endocrinology, School of Medicine, Pontificia Universidad Catolica De Chile, Santiago, Chile.

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http://dx.doi.org/10.1097/01.mnh.0000436543.48391.e0DOI Listing
January 2014

Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake.

Age (Dordr) 2013 Oct 2;35(5):1809-20. Epub 2012 Oct 2.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA,

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http://link.springer.com/10.1007/s11357-012-9480-0
Publisher Site
http://dx.doi.org/10.1007/s11357-012-9480-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776098PMC
October 2013

The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes.

Metabolism 2013 Apr 9;62(4):539-47. Epub 2012 Nov 9.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.metabol.2012.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572332PMC
April 2013

Abnormal aldosterone physiology and cardiometabolic risk factors.

Hypertension 2013 Apr 11;61(4):886-93. Epub 2013 Feb 11.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615445PMC
April 2013

Effect of low dose mineralocorticoid receptor antagonist eplerenone on glucose and lipid metabolism in healthy adult males.

Metabolism 2013 Mar 21;62(3):386-91. Epub 2012 Sep 21.

Brigham and Women's Hospital, Harvard Medical School, Division of Endocrinology, Diabetes, and Hypertension, Boston, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002604951200315
Publisher Site
http://dx.doi.org/10.1016/j.metabol.2012.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403630PMC
March 2013

Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice.

Metabolism 2013 Feb 4;62(2):275-81. Epub 2012 Sep 4.

Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.metabol.2012.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518593PMC
February 2013

Correlation of glycyrrhetinic acid-like factors (kidney 11beta-HSD2-GALFs) with urinary free cortisol and plasma renin activity in essential hypertension.

J Am Soc Hypertens 2008 Jul-Aug;2(4):286-93. Epub 2008 Jun 2.

Department of Pathology and Laboratory Medicine, The Miriam Hospital, Brown University Medical School, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1016/j.jash.2008.01.001DOI Listing
October 2012

Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus.

J Clin Endocrinol Metab 2012 Oct 3;97(10):3775-82. Epub 2012 Aug 3.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, RFB 386, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1210/jc.2012-2127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462947PMC
October 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1002607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315470PMC
September 2012

Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension.

J Clin Endocrinol Metab 2012 Sep 20;97(9):E1825-9. Epub 2012 Jun 20.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.

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September 2012

A genome-wide association search for type 2 diabetes genes in African Americans.

Authors:
Nicholette D Palmer Caitrin W McDonough Pamela J Hicks Bong H Roh Maria R Wing S Sandy An Jessica M Hester Jessica N Cooke Meredith A Bostrom Megan E Rudock Matthew E Talbert Joshua P Lewis Assiamira Ferrara Lingyi Lu Julie T Ziegler Michele M Sale Jasmin Divers Daniel Shriner Adebowale Adeyemo Charles N Rotimi Maggie C Y Ng Carl D Langefeld Barry I Freedman Donald W Bowden Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Andrew P Morris Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Claudia Langenberg Oliver M Hofmann Josée Dupuis Lu Qi Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis David J Couper Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Norman Klopp Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne John R B Perry Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Karen L Mohlke Andrew D Morris Colin N A Palmer Peter P Pramstaller Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Nicholas J Wareham Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Frank B Hu James B Meigs James S Pankow Oluf Pedersen H-Erich Wichmann Inês Barroso Jose C Florez Timothy M Frayling Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Toby Johnson Paul Elliott Denis Rybin Peter Henneman Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Josephine M Egan Taina Lajunen Alex Doney Stavroula Kanoni Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg Andrew A Hicks David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Lars Lind Lyle J Palmer Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Luigi Ferrucci Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Robert Sladek

PLoS One 2012 4;7(1):e29202. Epub 2012 Jan 4.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251563PMC
May 2012

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.

Authors:
Robert A Scott Audrey Y Chu Niels Grarup Alisa K Manning Marie-France Hivert Dmitry Shungin Anke Tönjes Ajay Yesupriya Daniel Barnes Nabila Bouatia-Naji Nicole L Glazer Anne U Jackson Zoltán Kutalik Vasiliki Lagou Diana Marek Laura J Rasmussen-Torvik Heather M Stringham Toshiko Tanaka Mette Aadahl Dan E Arking Sven Bergmann Eric Boerwinkle Lori L Bonnycastle Stefan R Bornstein Eric Brunner Suzannah J Bumpstead Soren Brage Olga D Carlson Han Chen Yii-Der Ida Chen Peter S Chines Francis S Collins David J Couper Elaine M Dennison Nicole F Dowling Josephine S Egan Ulf Ekelund Michael R Erdos Nita G Forouhi Caroline S Fox Mark O Goodarzi Jürgen Grässler Stefan Gustafsson Göran Hallmans Torben Hansen Aroon Hingorani John W Holloway Frank B Hu Bo Isomaa Karen A Jameson Ingegerd Johansson Anna Jonsson Torben Jørgensen Mika Kivimaki Peter Kovacs Meena Kumari Johanna Kuusisto Markku Laakso Cécile Lecoeur Claire Lévy-Marchal Guo Li Ruth J F Loos Valeri Lyssenko Michael Marmot Pedro Marques-Vidal Mario A Morken Gabriele Müller Kari E North James S Pankow Felicity Payne Inga Prokopenko Bruce M Psaty Frida Renström Ken Rice Jerome I Rotter Denis Rybin Camilla H Sandholt Avan A Sayer Peter Shrader Peter E H Schwarz David S Siscovick Alena Stancáková Michael Stumvoll Tanya M Teslovich Gérard Waeber Gordon H Williams Daniel R Witte Andrew R Wood Weijia Xie Michael Boehnke Cyrus Cooper Luigi Ferrucci Philippe Froguel Leif Groop W H Linda Kao Peter Vollenweider Mark Walker Richard M Watanabe Oluf Pedersen James B Meigs Erik Ingelsson Inês Barroso Jose C Florez Paul W Franks Josée Dupuis Nicholas J Wareham Claudia Langenberg

Diabetes 2012 May 13;61(5):1291-6. Epub 2012 Mar 13.

Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK.

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May 2012

Activation of the mineralocorticoid receptor increases striatin levels.

Am J Hypertens 2012 Feb 17;25(2):243-9. Epub 2011 Nov 17.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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February 2012

Altered systemic hemodynamic and baroreflex response to angiotensin II in postural tachycardia syndrome.

Circ Arrhythm Electrophysiol 2012 Feb 13;5(1):173-80. Epub 2012 Jan 13.

Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232-2195, USA.

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February 2012

Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses.

J Renin Angiotensin Aldosterone Syst 2011 Dec 13;12(4):564-71. Epub 2011 Apr 13.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115 , USA.

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December 2011

Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.

Am J Physiol Heart Circ Physiol 2011 Nov 26;301(5):H1862-71. Epub 2011 Aug 26.

Cardiovascular Endocrine Section, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

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November 2011

Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans.

Am J Hypertens 2011 Oct 30;24(10):1143-8. Epub 2011 Jun 30.

Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's and Harvard Medical School, Boston, Massachusetts, USA.

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October 2011

Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart.

J Endocrinol 2011 Oct 11;211(1):47-54. Epub 2011 Jul 11.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.

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October 2011

Exercise training versus propranolol in the treatment of the postural orthostatic tachycardia syndrome.

Hypertension 2011 Aug 20;58(2):167-75. Epub 2011 Jun 20.

Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, 7232 Greenville Ave, Suite 435, Dallas, TX 75231, USA.

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August 2011

Low-salt diet increases insulin resistance in healthy subjects.

Metabolism 2011 Jul 30;60(7):965-8. Epub 2010 Oct 30.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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July 2011

Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization.

Am J Physiol Heart Circ Physiol 2011 Jul 2;301(1):H41-7. Epub 2011 May 2.

Div. of Vascular and Endovascular Surgery, Univ. of California San Francisco, 400 Parnassus Ave., Ste. A581, San Francisco, CA 94143-0222, USA.

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July 2011

The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men.

Eur J Endocrinol 2011 Jun 14;164(6):995-1002. Epub 2011 Mar 14.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, 221 Longwood Avenue, RFB 386, Boston, Massachusetts 02115, USA.

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June 2011

Cell membrane-associated mineralocorticoid receptors? New evidence.

Hypertension 2011 Jun 11;57(6):1019-25. Epub 2011 Apr 11.

Brigham and Women's Hospital/Harvard Medical School, Division of Endocrinology, Diabetes, and Hypertension, 221 Longwood Ave, Boston, MA 02115, USA.

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June 2011

The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians.

Clin Endocrinol (Oxf) 2011 Jun;74(6):783-90

Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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June 2011

The association of plasma resistin with dietary sodium manipulation, the renin-angiotensin-aldosterone system, and 25-hydroxyvitamin D3 in human hypertension.

Clin Endocrinol (Oxf) 2011 Mar;74(3):294-9

Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA.

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March 2011

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.

Authors:
Nicole Soranzo Serena Sanna Eleanor Wheeler Christian Gieger Dörte Radke Josée Dupuis Nabila Bouatia-Naji Claudia Langenberg Inga Prokopenko Elliot Stolerman Manjinder S Sandhu Matthew M Heeney Joseph M Devaney Muredach P Reilly Sally L Ricketts Alexandre F R Stewart Benjamin F Voight Christina Willenborg Benjamin Wright David Altshuler Dan Arking Beverley Balkau Daniel Barnes Eric Boerwinkle Bernhard Böhm Amélie Bonnefond Lori L Bonnycastle Dorret I Boomsma Stefan R Bornstein Yvonne Böttcher Suzannah Bumpstead Mary Susan Burnett-Miller Harry Campbell Antonio Cao John Chambers Robert Clark Francis S Collins Josef Coresh Eco J C de Geus Mariano Dei Panos Deloukas Angela Döring Josephine M Egan Roberto Elosua Luigi Ferrucci Nita Forouhi Caroline S Fox Christopher Franklin Maria Grazia Franzosi Sophie Gallina Anuj Goel Jürgen Graessler Harald Grallert Andreas Greinacher David Hadley Alistair Hall Anders Hamsten Caroline Hayward Simon Heath Christian Herder Georg Homuth Jouke-Jan Hottenga Rachel Hunter-Merrill Thomas Illig Anne U Jackson Antti Jula Marcus Kleber Christopher W Knouff Augustine Kong Jaspal Kooner Anna Köttgen Peter Kovacs Knut Krohn Brigitte Kühnel Johanna Kuusisto Markku Laakso Mark Lathrop Cécile Lecoeur Man Li Mingyao Li Ruth J F Loos Jian'an Luan Valeriya Lyssenko Reedik Mägi Patrik K E Magnusson Anders Mälarstig Massimo Mangino María Teresa Martínez-Larrad Winfried März Wendy L McArdle Ruth McPherson Christa Meisinger Thomas Meitinger Olle Melander Karen L Mohlke Vincent E Mooser Mario A Morken Narisu Narisu David M Nathan Matthias Nauck Chris O'Donnell Konrad Oexle Nazario Olla James S Pankow Felicity Payne John F Peden Nancy L Pedersen Leena Peltonen Markus Perola Ozren Polasek Eleonora Porcu Daniel J Rader Wolfgang Rathmann Samuli Ripatti Ghislain Rocheleau Michael Roden Igor Rudan Veikko Salomaa Richa Saxena David Schlessinger Heribert Schunkert Peter Schwarz Udo Seedorf Elizabeth Selvin Manuel Serrano-Ríos Peter Shrader Angela Silveira David Siscovick Kjioung Song Timothy D Spector Kari Stefansson Valgerdur Steinthorsdottir David P Strachan Rona Strawbridge Michael Stumvoll Ida Surakka Amy J Swift Toshiko Tanaka Alexander Teumer Gudmar Thorleifsson Unnur Thorsteinsdottir Anke Tönjes Gianluca Usala Veronique Vitart Henry Völzke Henri Wallaschofski Dawn M Waterworth Hugh Watkins H-Erich Wichmann Sarah H Wild Gonneke Willemsen Gordon H Williams James F Wilson Juliane Winkelmann Alan F Wright Carina Zabena Jing Hua Zhao Stephen E Epstein Jeanette Erdmann Hakon H Hakonarson Sekar Kathiresan Kay-Tee Khaw Robert Roberts Nilesh J Samani Mark D Fleming Robert Sladek Gonçalo Abecasis Michael Boehnke Philippe Froguel Leif Groop Mark I McCarthy W H Linda Kao Jose C Florez Manuela Uda Nicholas J Wareham Inês Barroso James B Meigs

Diabetes 2010 Dec 21;59(12):3229-39. Epub 2010 Sep 21.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992787PMC
December 2010

The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study.

J Clin Endocrinol Metab 2010 Sep 14;95(9):E75-9. Epub 2010 Jul 14.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.

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September 2010

Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice.

Am J Physiol Heart Circ Physiol 2010 Jun 2;298(6):H1776-88. Epub 2010 Apr 2.

Cardiovascular Endocrine Section, Endocrinology, Diabetes and Hypertension Division, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1152/ajpheart.00661.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886646PMC
June 2010

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.

Diabetes 2010 May 25;59(5):1266-75. Epub 2010 Feb 25.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857908PMC
May 2010

Aldosterone production and insulin resistance in healthy adults.

J Clin Endocrinol Metab 2010 Apr 3;95(4):1986-90. Epub 2010 Feb 3.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853992PMC
April 2010

Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II.

Endocrinology 2010 Mar 22;151(3):1236-46. Epub 2010 Jan 22.

Brigham and Women's Hospital/Harvard Medical School, Department of Endocrinology, Diabetes, and Hypertension, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840694PMC
March 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Authors:
Richa Saxena Marie-France Hivert Claudia Langenberg Toshiko Tanaka James S Pankow Peter Vollenweider Valeriya Lyssenko Nabila Bouatia-Naji Josée Dupuis Anne U Jackson W H Linda Kao Man Li Nicole L Glazer Alisa K Manning Jian'an Luan Heather M Stringham Inga Prokopenko Toby Johnson Niels Grarup Trine W Boesgaard Cécile Lecoeur Peter Shrader Jeffrey O'Connell Erik Ingelsson David J Couper Kenneth Rice Kijoung Song Camilla H Andreasen Christian Dina Anna Köttgen Olivier Le Bacquer François Pattou Jalal Taneera Valgerdur Steinthorsdottir Denis Rybin Kristin Ardlie Michael Sampson Lu Qi Mandy van Hoek Michael N Weedon Yurii S Aulchenko Benjamin F Voight Harald Grallert Beverley Balkau Richard N Bergman Suzette J Bielinski Amelie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Thomas A Buchanan Suzannah J Bumpstead Christine Cavalcanti-Proença Guillaume Charpentier Yii-Der Ida Chen Peter S Chines Francis S Collins Marilyn Cornelis Gabriel J Crawford Jerome Delplanque Alex Doney Josephine M Egan Michael R Erdos Mathieu Firmann Nita G Forouhi Caroline S Fox Mark O Goodarzi Jürgen Graessler Aroon Hingorani Bo Isomaa Torben Jørgensen Mika Kivimaki Peter Kovacs Knut Krohn Meena Kumari Torsten Lauritzen Claire Lévy-Marchal Vladimir Mayor Jarred B McAteer David Meyre Braxton D Mitchell Karen L Mohlke Mario A Morken Narisu Narisu Colin N A Palmer Ruth Pakyz Laura Pascoe Felicity Payne Daniel Pearson Wolfgang Rathmann Annelli Sandbaek Avan Aihie Sayer Laura J Scott Stephen J Sharp Eric Sijbrands Andrew Singleton David S Siscovick Nicholas L Smith Thomas Sparsø Amy J Swift Holly Syddall Gudmar Thorleifsson Anke Tönjes Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Gérard Waeber Andrew Walley Dawn M Waterworth Eleftheria Zeggini Jing Hua Zhao Thomas Illig H Erich Wichmann James F Wilson Cornelia van Duijn Frank B Hu Andrew D Morris Timothy M Frayling Andrew T Hattersley Unnur Thorsteinsdottir Kari Stefansson Peter Nilsson Ann-Christine Syvänen Alan R Shuldiner Mark Walker Stefan R Bornstein Peter Schwarz Gordon H Williams David M Nathan Johanna Kuusisto Markku Laakso Cyrus Cooper Michael Marmot Luigi Ferrucci Vincent Mooser Michael Stumvoll Ruth J F Loos David Altshuler Bruce M Psaty Jerome I Rotter Eric Boerwinkle Torben Hansen Oluf Pedersen Jose C Florez Mark I McCarthy Michael Boehnke Inês Barroso Robert Sladek Philippe Froguel James B Meigs Leif Groop Nicholas J Wareham Richard M Watanabe

Nat Genet 2010 Feb 17;42(2):142-8. Epub 2010 Jan 17.

Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922003PMC
February 2010

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

Authors:
Josée Dupuis Claudia Langenberg Inga Prokopenko Richa Saxena Nicole Soranzo Anne U Jackson Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Anna L Gloyn Cecilia M Lindgren Reedik Mägi Andrew P Morris Joshua Randall Toby Johnson Paul Elliott Denis Rybin Gudmar Thorleifsson Valgerdur Steinthorsdottir Peter Henneman Harald Grallert Abbas Dehghan Jouke Jan Hottenga Christopher S Franklin Pau Navarro Kijoung Song Anuj Goel John R B Perry Josephine M Egan Taina Lajunen Niels Grarup Thomas Sparsø Alex Doney Benjamin F Voight Heather M Stringham Man Li Stavroula Kanoni Peter Shrader Christine Cavalcanti-Proença Meena Kumari Lu Qi Nicholas J Timpson Christian Gieger Carina Zabena Ghislain Rocheleau Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Felicity Payne Rosa Maria Roccasecca François Pattou Praveen Sethupathy Kristin Ardlie Yavuz Ariyurek Beverley Balkau Philip Barter John P Beilby Yoav Ben-Shlomo Rafn Benediktsson Amanda J Bennett Sven Bergmann Murielle Bochud Eric Boerwinkle Amélie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Guillaume Charpentier Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Marilyn Cornelis Gabe Crawford Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Christian Dina Michael R Erdos Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Caroline S Fox Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Christopher J Groves Scott Grundy Rhian Gwilliam Ulf Gyllensten Samy Hadjadj Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Neelam Hassanali Caroline Hayward Simon C Heath Serge Hercberg Christian Herder Andrew A Hicks David R Hillman Aroon D Hingorani Albert Hofman Jennie Hui Joe Hung Bo Isomaa Paul R V Johnson Torben Jørgensen Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Valeriya Lyssenko Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Laura J McCulloch Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Mario A Morken Sutapa Mukherjee Silvia Naitza Narisu Narisu Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Colin N A Palmer Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Wolfgang Rathmann Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Michael Roden Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Laura J Scott Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurethsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Barbara Thorand Jean Tichet Anke Tönjes Tiinamaija Tuomi André G Uitterlinden Ko Willems van Dijk Mandy van Hoek Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley G Bragi Walters Kim L Ward Hugh Watkins Michael N Weedon Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Eleftheria Zeggini Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Andrew T Hattersley Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Andrew D Morris Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao James S Pankow Michael J Sampson Johanna Kuusisto Markku Laakso Torben Hansen Oluf Pedersen Peter Paul Pramstaller H Erich Wichmann Thomas Illig Igor Rudan Alan F Wright Michael Stumvoll Harry Campbell James F Wilson Richard N Bergman Thomas A Buchanan Francis S Collins Karen L Mohlke Jaakko Tuomilehto Timo T Valle David Altshuler Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Timothy M Frayling Luigi Ferrucci Augustine Kong Unnur Thorsteinsdottir Kari Stefansson Cornelia M van Duijn Yurii S Aulchenko Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Goncalo R Abecasis Nicholas J Wareham Robert Sladek Philippe Froguel Richard M Watanabe James B Meigs Leif Groop Michael Boehnke Mark I McCarthy Jose C Florez Inês Barroso

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