Publications


An evaluation of purified Salmonella Typhi protein antigens for the serological diagnosis of acute typhoid fever.
J Infect 2017 Aug 25;75(2):104-114. Epub 2017 May 25.
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam; Centre for Tropical Medicine and Global Health, Oxford University, Oxford, United Kingdom; The Department of Medicine, University of Cambridge, Cambridge, United Kingdom. Electronic address:







Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.
Cell Metab 2016 Nov 27;24(5):740-752. Epub 2016 Oct 27.
Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK. Electronic address:












Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen.
PLoS One 2016 7;11(1):e0145945. Epub 2016 Jan 7.
School of Immunity and Infection, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.



Transfer of scarlet fever-associated elements into the group A Streptococcus M1T1 clone.
Sci Rep 2015 Nov 2;5:15877. Epub 2015 Nov 2.
Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.

Discovery and Characterization of Human-Urine Utilization by Asymptomatic-Bacteriuria-Causing Streptococcus agalactiae.
Infect Immun 2015 Nov 9;84(1):307-19. Epub 2015 Nov 9.
School of Medical Sciences, Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, QLD, Australia Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA



Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease.
PLoS Negl Trop Dis 2015 Jun 11;9(6):e0003837. Epub 2015 Jun 11.
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
PLoS Pathog 2015 May 22;11(5):e1004914. Epub 2015 May 22.
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.
PLoS Negl Trop Dis 2015 Apr 24;9(4):e0003748. Epub 2015 Apr 24.
Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi; Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa.
PLoS Negl Trop Dis 2015 Mar 24;9(3):e0003611. Epub 2015 Mar 24.
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; Institute of Food Research, Norwich Research Park, Norwich, Norfolk, United Kingdom.

Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance.
Nat Genet 2015 Jan 17;47(1):84-7. Epub 2014 Nov 17.
Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, St. Lucia, Queensland, Australia.

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.
J Bacteriol 2015 Jan 17;197(2):392-403. Epub 2014 Nov 17.
Department of Microbiology and Immunology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden


The Hd, Hj, and Hz66 flagella variants of Salmonella enterica serovar Typhi modify host responses and cellular interactions.
Sci Rep 2015 Jan 22;5:7947. Epub 2015 Jan 22.
1] The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, United Kingdom [3] The London School of Hygiene and Tropical Medicine, London, United Kingdom.

Typhoid fever in Fiji: a reversible plague?
Trop Med Int Health 2014 Oct 25;19(10):1284-92. Epub 2014 Jul 25.
Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, UK.


Transient Darwinian selection in Salmonella enterica serovar Paratyphi A during 450 years of global spread of enteric fever.
Proc Natl Acad Sci U S A 2014 Aug 4;111(33):12199-204. Epub 2014 Aug 4.
Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom;Environmental Research Institute and Department of Microbiology, University College Cork, Cork, Ireland;

The population structure of Vibrio cholerae from the Chandigarh Region of Northern India.
PLoS Negl Trop Dis 2014 Jul 24;8(7):e2981. Epub 2014 Jul 24.
Pathogen Genomics Laboratory, Computational Bioscience Research Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia.



Global dissemination of a multidrug resistant Escherichia coli clone.
Proc Natl Acad Sci U S A 2014 Apr 31;111(15):5694-9. Epub 2014 Mar 31.
Australian Infectious Diseases Research Centre, and School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.





Identification of Salmonella enterica serovar Typhi genotypes by use of rapid multiplex ligation-dependent probe amplification.
J Clin Microbiol 2013 Sep 3;51(9):2950-8. Epub 2013 Jul 3.
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.




The Molecular and Spatial Epidemiology of Typhoid Fever in Rural Cambodia.
PLoS Negl Trop Dis 2016 06 22;10(6):e0004785. Epub 2016 Jun 22.
The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.

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