Gonzalo De Prat-Gay

Gonzalo De Prat-Gay

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Gonzalo De Prat-Gay

Gonzalo De Prat-Gay

Publications by authors named "Gonzalo De Prat-Gay"

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The structure of the extended E2 DNA-binding domain of the bovine papillomavirus-1.

Proteins 2020 Jan 1;88(1):106-112. Epub 2019 Aug 1.

Laboratório de Cristalografia, Physics Department, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

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http://dx.doi.org/10.1002/prot.25773DOI Listing
January 2020

Topology Dictates Evolution of Regulatory Cysteines in a Family of Viral Oncoproteins.

Mol Biol Evol 2019 07;36(7):1521-1532

Instituto de Nanobiotecnología (NANOBIOTEC), CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina.

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https://academic.oup.com/mbe/advance-article/doi/10.1093/mol
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http://dx.doi.org/10.1093/molbev/msz085DOI Listing
July 2019

Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus.

Biochemistry 2019 Jul 19;58(26):2883-2892. Epub 2019 Jun 19.

Protein Structure-Function and Engineering Laboratory , Fundación Instituto Leloir and IIBBA-CONICET , Av. Patricias Argentinas 435 , 1405 Buenos Aires , Argentina.

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http://dx.doi.org/10.1021/acs.biochem.8b01288DOI Listing
July 2019

Interplay between sequence, structure and linear motifs in the adenovirus E1A hub protein.

Virology 2018 12 25;525:117-131. Epub 2018 Sep 25.

Universidad de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN). Facultad de Ciencias Exactas y Naturales. Laboratorio de Fisiología de Proteínas. Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2018.08.012DOI Listing
December 2018

Mechanism of Tetramer Dissociation, Unfolding, and Oligomer Assembly of M2-1 Transcription Antiterminators.

ACS Omega 2018 Nov 2;3(11):14732-14745. Epub 2018 Nov 2.

Protein Structure, Function and Engineering Laboratory, Fundación Instituto Leloir, IIBBA, Avenida Patricias Argentinas 435, 1405 CABA, Argentina.

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http://dx.doi.org/10.1021/acsomega.8b01600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289497PMC
November 2018

Cooperative RNA Recognition by a Viral Transcription Antiterminator.

J Mol Biol 2018 03 4;430(6):777-792. Epub 2018 Feb 4.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.01.018DOI Listing
March 2018

Structure and stability of the Human respiratory syncytial virus M RNA-binding core domain reveals a compact and cooperative folding unit.

Acta Crystallogr F Struct Biol Commun 2018 Jan 15;74(Pt 1):23-30. Epub 2017 Dec 15.

The Hamburg Centre for Ultrafast Imaging and Department of Chemistry, Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.

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http://dx.doi.org/10.1107/S2053230X17017381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947689PMC
January 2018

Hidden Structural Codes in Protein Intrinsic Disorder.

Biochemistry 2017 10 6;56(41):5560-5569. Epub 2017 Oct 6.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas de Buenos Aires (IIBBA) CONICET , Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/acs.biochem.7b00721DOI Listing
October 2017

Regulation of Tacaribe Mammarenavirus Translation: Positive 5' and Negative 3' Elements and Role of Key Cellular Factors.

J Virol 2017 07 26;91(14). Epub 2017 Jun 26.

Centro de Virología Animal, Instituto de Ciencia y Tecnología Dr. Cesar Milstein, Consejo Nacional de Ciencia y Tecnología, Buenos Aires, Argentina

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http://dx.doi.org/10.1128/JVI.00084-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487564PMC
July 2017

Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein.

Redox Biol 2017 04 12;11:38-50. Epub 2016 Nov 12.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2016.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278158PMC
April 2017

Intrinsic Disorder to Order Transitions in the Scaffold Phosphoprotein P from the Respiratory Syncytial Virus RNA Polymerase Complex.

Biochemistry 2016 Mar 4;55(10):1441-54. Epub 2016 Mar 4.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET , Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/acs.biochem.5b01332DOI Listing
March 2016

Conformational Heterogeneity Determined by Folding and Oligomer Assembly Routes of the Interferon Response Inhibitor NS1 Protein, Unique to Human Respiratory Syncytial Virus.

Biochemistry 2015 Aug 12;54(33):5136-46. Epub 2015 Aug 12.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET , Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/acs.biochem.5b00615DOI Listing
August 2015

Convergent evolution and mimicry of protein linear motifs in host-pathogen interactions.

Curr Opin Struct Biol 2015 Jun 2;32:91-101. Epub 2015 Apr 2.

Protein Physiology Laboratory, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales and IQUIBICEN-CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2015.03.004DOI Listing
June 2015

Conformational dissection of a viral intrinsically disordered domain involved in cellular transformation.

PLoS One 2013 27;8(9):e72760. Epub 2013 Sep 27.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA- CONICET, Buenos Aires, Argentina.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072760PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785498PMC
July 2014

The non-structural NS1 protein unique to respiratory syncytial virus: a two-state folding monomer in quasi-equilibrium with a stable spherical oligomer.

PLoS One 2013 10;8(9):e74338. Epub 2013 Sep 10.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074338PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769240PMC
June 2014

Cysteine-rich positions outside the structural zinc motif of human papillomavirus E7 provide conformational modulation and suggest functional redox roles.

Biochemistry 2014 Mar 6;53(10):1680-96. Epub 2014 Mar 6.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET , Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi401562eDOI Listing
March 2014

Fine modulation of the respiratory syncytial virus M2-1 protein quaternary structure by reversible zinc removal from its Cys(3)-His(1) motif.

Biochemistry 2013 Oct 19;52(39):6779-89. Epub 2013 Sep 19.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBA-Conicet , Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi401029qDOI Listing
October 2013

Folding of a cyclin box: linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor AB pocket domain.

J Biol Chem 2013 Jun 30;288(26):18923-38. Epub 2013 Apr 30.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Avenida Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1074/jbc.M113.467316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696668PMC
June 2013

Sequence evolution of the intrinsically disordered and globular domains of a model viral oncoprotein.

PLoS One 2012 31;7(10):e47661. Epub 2012 Oct 31.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047661PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485249PMC
May 2013

Minute time scale prolyl isomerization governs antibody recognition of an intrinsically disordered immunodominant epitope.

J Biol Chem 2013 May 15;288(18):13110-23. Epub 2013 Mar 15.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir, IIBBA-CONICET, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.444554
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http://dx.doi.org/10.1074/jbc.M112.444554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642352PMC
May 2013

Circular dichroism techniques for the analysis of intrinsically disordered proteins and domains.

Methods Mol Biol 2012 ;895:387-404

Protein Structure, Function and Engineering Laboratory, Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas, Buenos Aires, Argentina.

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http://link.springer.com/content/pdf/10.1007/978-1-61779-927
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http://link.springer.com/10.1007/978-1-61779-927-3_22
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http://dx.doi.org/10.1007/978-1-61779-927-3_22DOI Listing
October 2012

Modular unfolding and dissociation of the human respiratory syncytial virus phosphoprotein p and its interaction with the m(2-1) antiterminator: a singular tetramer-tetramer interface arrangement.

Biochemistry 2012 Oct 4;51(41):8100-10. Epub 2012 Oct 4.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi300765cDOI Listing
October 2012

Evolution of linear motifs within the papillomavirus E7 oncoprotein.

J Mol Biol 2012 Sep 6;422(3):336-46. Epub 2012 Jun 6.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Patricias Argentinas 435 (1405), Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jmb.2012.05.036DOI Listing
September 2012

Long-lasting immunoprotective and therapeutic effects of a hyperstable E7 oligomer based vaccine in a murine human papillomavirus tumor model.

Int J Cancer 2012 Apr 24;130(8):1813-20. Epub 2011 Aug 24.

XBio SA, Concepción Arenal 4220, Ciudad de Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/ijc.26294DOI Listing
April 2012

The respiratory syncytial virus transcription antiterminator M(2-1) is a highly stable, zinc binding tetramer with strong pH-dependent dissociation and a monomeric unfolding intermediate.

Biochemistry 2011 Oct 15;50(40):8529-39. Epub 2011 Sep 15.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBA-Conicet, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi200661kDOI Listing
October 2011

Kinetic recognition of the retinoblastoma tumor suppressor by a specific protein target.

J Mol Biol 2011 Sep 26;412(2):267-84. Epub 2011 Jul 26.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Avenida Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jmb.2011.07.015DOI Listing
September 2011

E6*, the 50 amino acid product of the most abundant spliced transcript of the e6 oncoprotein in high-risk human papillomavirus, is a promiscuous folder and binder.

Biochemistry 2011 Mar 3;50(8):1376-83. Epub 2011 Feb 3.

Instituto Leloir and Instituto de Investigaciones Bioquímicas-Conicet, Patricias Argentinas 435, Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi101941cDOI Listing
March 2011

Mutational analysis of kinetic partitioning in protein folding and protein-DNA binding.

Protein Eng Des Sel 2011 Jan 27;24(1-2):179-84. Epub 2010 Sep 27.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1093/protein/gzq064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003449PMC
January 2011

Thermodynamics of cooperative DNA recognition at a replication origin and transcription regulatory site.

Biochemistry 2010 Dec 10;49(48):10277-86. Epub 2010 Nov 10.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-Conicet, Patricias Argentinas 435, Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi1014908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091369PMC
December 2010

Experimental snapshots of a protein-DNA binding landscape.

Proc Natl Acad Sci U S A 2010 Apr 7;107(17):7751-6. Epub 2010 Apr 7.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

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http://dx.doi.org/10.1073/pnas.0911734107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867883PMC
April 2010

Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7.

FEBS J 2010 Feb 20;277(4):973-88. Epub 2010 Jan 20.

Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07540.xDOI Listing
February 2010

The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins.

Biochemistry 2009 Dec;48(50):11939-49

Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas, CONICET, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi901415kDOI Listing
December 2009

Cytosolic accumulation of HPV16 E7 oligomers supports different transformation routes for the prototypic viral oncoprotein: the amyloid-cancer connection.

Int J Cancer 2009 Oct;125(8):1902-11

Instituto Leloir and Instituto de Investigaciones Bioquímicas Buenos Aires, Conicet, Patricias Argentinas 435, (C1405BWE) Ciudad Autonoma de Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/ijc.24579DOI Listing
October 2009

Transition state for protein-DNA recognition.

Proc Natl Acad Sci U S A 2008 Aug 29;105(31):10797-802. Epub 2008 Jul 29.

Fundación Instituto Leloir and Instituto de Investigaciones Bioquímicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas de Argentina, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1073/pnas.0802383105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504826PMC
August 2008

The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis.

J Biol Chem 2008 Jun 14;283(25):17039-48. Epub 2008 Apr 14.

Fundación Instituto Leloir-Instituto de Investigaciones Bioquímicas de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), 435 Av. Patricias Argentinas, Ciudad de Buenos Aires C1405BWE, Argentina.

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http://dx.doi.org/10.1074/jbc.M706316200DOI Listing
June 2008

The papillomavirus E2 DNA binding domain.

Front Biosci 2008 May 1;13:6006-21. Epub 2008 May 1.

Instituto Leloir and IIBBA-CONICET, Av. Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.2741/3132DOI Listing
May 2008

Kinetically driven refolding of the hyperstable EBNA1 origin DNA-binding dimeric beta-barrel domain into amyloid-like spherical oligomers.

Proteins 2008 Feb;70(2):450-61

Instituto Leloir, Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/prot.21580DOI Listing
February 2008

Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics.

Nucleic Acids Res 2008 Feb 15;36(3):756-69. Epub 2007 Dec 15.

Fundación Instituto Leloir and IIBBA-Conicet, Patricias Argentinas 435 (1405), Buenos Aires, Argentina.

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http://dx.doi.org/10.1093/nar/gkm1104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241901PMC
February 2008

Increased stability and DNA site discrimination of "single chain" variants of the dimeric beta-barrel DNA binding domain of the human papillomavirus E2 transcriptional regulator.

Biochemistry 2007 Oct 4;46(43):12441-50. Epub 2007 Oct 4.

Instituto Leloir and IIBBA-Conicet, Patricias Argentinas 435 (1405), Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi701104qDOI Listing
October 2007

The N-terminal module of HPV16 E7 is an intrinsically disordered domain that confers conformational and recognition plasticity to the oncoprotein.

Biochemistry 2007 Sep 23;46(37):10405-12. Epub 2007 Aug 23.

Instituto Leloir and IIB-BA CONICET, Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi7007917DOI Listing
September 2007

Specific recognition of a DNA immunogen by its elicited antibody.

J Mol Biol 2007 Jun 24;370(1):183-95. Epub 2007 Apr 24.

Instituto Leloir and CONICET, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jmb.2007.04.046DOI Listing
June 2007

High-risk HPV E6 oncoproteins assemble into large oligomers that allow localization of endogenous species in prototypic HPV-transformed cell lines.

Biochemistry 2007 Jan;46(2):341-9

Instituto Leloir and CONICET, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi602457qDOI Listing
January 2007

Antibody recognition of a flexible epitope at the DNA binding site of the human papillomavirus transcriptional regulator E2.

Biochemistry 2006 Dec;45(51):15520-8

Fundación Instituto Leloir, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi0615184DOI Listing
December 2006

Mechanism of DNA recognition at a viral replication origin.

J Biol Chem 2006 Sep 29;281(37):26893-903. Epub 2006 Jun 29.

Instituto Leloir, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1074/jbc.M602083200DOI Listing
September 2006

Structural and thermodynamic basis for the enhanced transcriptional control by the human papillomavirus strain-16 E2 protein.

Biochemistry 2006 May;45(21):6551-60

Instituto Leloir and CONICET, University of Rome Tor Vergata, via della Ricerca Scientifica, 00133 Rome, Italy Tor Vergata.

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http://dx.doi.org/10.1021/bi060123hDOI Listing
May 2006

Chaperone holdase activity of human papillomavirus E7 oncoprotein.

Biochemistry 2006 Jan;45(3):657-67

Instituto Leloir and CONICET, Patricias Argentinas 435, 1405 Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi0522549DOI Listing
January 2006

Free energy contributions to direct readout of a DNA sequence.

J Biol Chem 2005 Sep 5;280(37):32480-4. Epub 2005 Jul 5.

Instituto Leloir, Consejo Nacional de Investigaciones Científicas y Técnicas, and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.

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http://dx.doi.org/10.1074/jbc.M505706200DOI Listing
September 2005

The folding mechanism of a dimeric beta-barrel domain.

J Mol Biol 2005 Aug;351(3):672-82

Instituto Leloir, CONICET, and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jmb.2005.05.070DOI Listing
August 2005

Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia.

Biochem Biophys Res Commun 2005 Jul;332(3):808-16

Fundación Instituto Leloir, Instituto de Investigaciones Bioquímicas de Buenos Aires, (CONICET), Patricias Argentinas 435, Buenos Aires 1405, Argentina.

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http://dx.doi.org/10.1016/j.bbrc.2005.05.020DOI Listing
July 2005

A viral DNA-binding domain elicits anti-DNA antibodies of different specificities.

Mol Immunol 2005 Feb;42(3):327-33

Instituto Leloir, Consejo Nacional de Investigaciones Científicas y Técnicas and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.molimm.2004.09.003DOI Listing
February 2005

The endoplasmic reticulum glucosyltransferase recognizes nearly native glycoprotein folding intermediates.

J Biol Chem 2004 Oct 19;279(44):46280-5. Epub 2004 Aug 19.

Fundación Instituto Leloir, Buenos Aires, Argentina C1405BWE.

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http://dx.doi.org/10.1074/jbc.M408404200DOI Listing
October 2004

Casein Kinase II phosphorylation-induced conformational switch triggers degradation of the papillomavirus E2 protein.

J Biol Chem 2004 May 9;279(21):22430-9. Epub 2004 Mar 9.

Laboratory of Viral Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892-0455, USA.

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http://dx.doi.org/10.1074/jbc.M314340200DOI Listing
May 2004

The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers.

Biochemistry 2004 Mar;43(12):3310-7

Instituto Leloir, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi036037oDOI Listing
March 2004

A protein-DNA binding mechanism proceeds through multi-state or two-state parallel pathways.

J Mol Biol 2003 Aug;331(1):89-99

Instituto Leloir, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and CONICET. Patricias Argentinas 435, (1405), Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/s0022-2836(03)00720-4DOI Listing
August 2003

Specific antibody-DNA interaction: a novel strategy for tight DNA recognition.

Biochemistry 2003 May;42(20):6218-27

Instituto Leloir and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi026866uDOI Listing
May 2003

UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates.

Proc Natl Acad Sci U S A 2003 Jan 23;100(1):86-91. Epub 2002 Dec 23.

Instituto de Investigaciones Biotecnológicas, University of San Martin, 1650 San Martin, Argentina.

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http://dx.doi.org/10.1073/pnas.262661199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140890PMC
January 2003

Antibody response to a viral transcriptional regulator.

FEBS Lett 2003 Jan;534(1-3):202-6

Fundación Instituto Leloir (IIBBA-CONICET, IIB-FCEN-UBA), Av. Patricias Argentinas 435, Buenos Aires 1405, Argentina.

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http://dx.doi.org/10.1016/s0014-5793(02)03850-4DOI Listing
January 2003

High-risk (HPV16) human papillomavirus E7 oncoprotein is highly stable and extended, with conformational transitions that could explain its multiple cellular binding partners.

Biochemistry 2002 Aug;41(33):10510-8

Instituto Leloir, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Patricias Argentinas 435, (1405) Buenos Aires, Argentina.

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http://dx.doi.org/10.1021/bi025579nDOI Listing
August 2002