Publications by authors named "Gloria Merenda"

2 Publications

  • Page 1 of 1

Primary breast osteosarcoma mimicking calcified fibroadenoma on screening digital breast tomosynthesis mammogram.

Radiol Case Rep 2017 Dec 29;12(4):648-652. Epub 2017 Jul 29.

Department of Radiology, St. Louis University Hospital, 3655 Vista Ave., St. Louis, MO 63110, USA.

Primary breast osteosarcoma is a rare malignancy, with mostly case reports in the literature. The appearance of breast osteosarcoma on digital breast tomosynthesis imaging has not yet been described. A 69-year-old woman presents for routine screening mammography and is found to have a calcified mass in her right breast. Pattern of calcification appeared "sunburst" on digital breast tomosynthesis images. This mass was larger than on the previous year's mammogram, at which time it had been interpreted as a benign calcified fibroadenoma. The subsequent workup demonstrated the mass to reflect primary breast osteosarcoma. The patient's workup and treatment are detailed in this case. Primary breast osteosarcoma, although rare, should be included as a diagnostic consideration for breast masses with a sunburst pattern of calcifications, particularly when the mammographic appearance has changed.
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http://dx.doi.org/10.1016/j.radcr.2017.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823318PMC
December 2017

Papillary Fibroelastoma as a Cause of Cardiogenic Embolic Stroke in a -Thalassemia Patient: Case Report and Literature Review.

Case Rep Cardiol 2017 26;2017:8185601. Epub 2017 Mar 26.

Department of Internal Medicine, SSM St. Mary's Health Center, 6420 Clayton Rd, Richmond Heights, MO 63117, USA.

We describe a case of a young male without stroke risk factors who presented with a sudden onset of left-sided weakness, left hand numbness, and left eye blurriness. CT scan of the head without contrast and diffusion-weighted MRI of the brain with contrast revealed an ischemic stroke in the right middle cerebral artery distribution. Transesophageal echocardiography (TEE) revealed a mobile pedunculated mass on the posterior surface of the mitral valve. This mass was resected and pathology showed a cardiac papillary fibroelastoma (CPFE), which was determined to be the cause of the patient's cardioembolic stroke. Further workup also found that patient had microcytic anemia secondary to -thalassemia intermedia, a rare hematologic disorder due to defective hemoglobin synthesis. Recently, another case report suggested -thalassemia major may underlie the pathogenesis of CPFE. -Thalassemia major causes a state of chronic inflammation and endothelial damage, which can mediate CPFE formation. Based on literature review, this is the first case report of a CPFE in a patient with -thalassemia intermedia. This hypothesis-generating case report calls attention to the need for elucidating the relationship between CPFE and -thalassemia in future studies to better understand the diagnosis and management of a rare cardiac tumor.
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http://dx.doi.org/10.1155/2017/8185601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385231PMC
March 2017