Glenville Jones

Glenville Jones

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Glenville Jones

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A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene in renal and non-renal tissues.

J Biol Chem 2019 Sep 22;294(39):14467-14481. Epub 2019 Aug 22.

Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706

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http://dx.doi.org/10.1074/jbc.RA119.010173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768633PMC
September 2019

Update on pharmacologically-relevant vitamin D analogues.

Br J Clin Pharmacol 2019 Jun 22;85(6):1095-1102. Epub 2018 Nov 22.

Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1111/bcp.13781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533488PMC
June 2019

Mineral Homeostasis in Murine Fetuses Is Sensitive to Maternal Calcitriol but Not to Absence of Fetal Calcitriol.

J Bone Miner Res 2019 Apr 2;34(4):669-680. Epub 2019 Jan 2.

Faculty of Medicine-Endocrinology, Memorial University of Newfoundland, St. John's, Canada.

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http://doi.wiley.com/10.1002/jbmr.3642
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http://dx.doi.org/10.1002/jbmr.3642DOI Listing
April 2019

Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D.

J Steroid Biochem Mol Biol 2019 04 13;188:23-28. Epub 2018 Dec 13.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2018.12.001DOI Listing
April 2019

The discovery and synthesis of the nutritional factor vitamin D.

Authors:
Glenville Jones

Int J Paleopathol 2018 12 17;23:96-99. Epub 2018 Jan 17.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijpp.2018.01.002DOI Listing
December 2018

Calcitriol Accelerates Vascular Calcification Irrespective of Vitamin K Status in a Rat Model of Chronic Kidney Disease with Hyperphosphatemia and Secondary Hyperparathyroidism.

J Pharmacol Exp Ther 2018 09 14;366(3):433-445. Epub 2018 Jun 14.

Departments of Biomedical and Molecular Sciences (K.M.M., J.G.Z., M.K., K.L., E.W., H.B., G.J., M.A.A.) and Medicine (G.J., R.M.H.), Queen's University, Kingston, Ontario, Canada

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http://dx.doi.org/10.1124/jpet.117.247270DOI Listing
September 2018

Vitamin D Toxicity-A Clinical Perspective.

Front Endocrinol (Lausanne) 2018 20;9:550. Epub 2018 Sep 20.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.

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https://www.frontiersin.org/article/10.3389/fendo.2018.00550
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http://dx.doi.org/10.3389/fendo.2018.00550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158375PMC
September 2018

Optimal bone fracture repair requires 24R,25-dihydroxyvitamin D3 and its effector molecule FAM57B2.

J Clin Invest 2018 08 16;128(8):3546-3557. Epub 2018 Jul 16.

Research Centre, Shriners Hospitals for Children - Canada, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1172/JCI98093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063485PMC
August 2018

Serum 24,25-dihydroxyvitamin D response to native vitamin D and D Supplementation in patients with chronic kidney disease on hemodialysis.

Clin Nutr 2018 06 30;37(3):1041-1045. Epub 2017 Apr 30.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, K7L3N6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2017.04.020DOI Listing
June 2018

Genetic Diseases of Vitamin D Metabolizing Enzymes.

Endocrinol Metab Clin North Am 2017 12 5;46(4):1095-1117. Epub 2017 Oct 5.

Department of General Pediatrics, University Children's Hospital, Waldeyerstr. 22, D-48149 Muenster, Germany.

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http://dx.doi.org/10.1016/j.ecl.2017.07.011DOI Listing
December 2017

A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene essential for vitamin D activation.

J Biol Chem 2017 10 14;292(42):17541-17558. Epub 2017 Aug 14.

From the Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706 and.

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http://dx.doi.org/10.1074/jbc.M117.806901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655528PMC
October 2017

Randomized trial of two doses of vitamin D3 in preterm infants <32 weeks: Dose impact on achieving desired serum 25(OH)D3 in a NICU population.

PLoS One 2017 10;12(10):e0185950. Epub 2017 Oct 10.

Division of Medical Nutrition Education, School of Allied Health Professions, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634602PMC
October 2017

High-Dose Intramuscular Vitamin D Provides Long-Lasting Moderate Increases in Serum 25-Hydroxvitamin D Levels and Shorter-Term Changes in Plasma Calcium.

J AOAC Int 2017 Sep 11;100(5):1337-1344. Epub 2017 May 11.

Australian National University, Research School of Population Health, National Centre for Epidemiology and Public Health, Canberra, Australian Capital Territory.

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http://dx.doi.org/10.5740/jaoacint.17-0087DOI Listing
September 2017

Vitamin D-Dependent Rickets Type 1B (25-Hydroxylase Deficiency): A Rare Condition or a Misdiagnosed Condition?

J Bone Miner Res 2017 Sep 13;32(9):1893-1899. Epub 2017 Jul 13.

CHU de Nancy, Department of Pediatrics and Reference Center for Rare Hereditary Diseases of Metabolism, Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1002/jbmr.3181DOI Listing
September 2017

Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy.

Public Health Nutr 2017 Jul 18;20(10):1825-1835. Epub 2016 Apr 18.

1Centre of Research Excellence in Nutrition and Metabolism,Institute for Medical Research,University of Belgrade,Tadeusa Koscuska 1,11000 Belgrade,Serbia.

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http://dx.doi.org/10.1017/S1368980016000409DOI Listing
July 2017

Calcium pyrophosphate deposition disease revealing a hypersensitivity to vitamin D.

Joint Bone Spine 2017 May 18;84(3):349-351. Epub 2017 Jan 18.

Department of Rheumatology, CHU de Caen, avenue Cote de Nacre, 14000 Caen, France; Normandy University, 14032 Caen cedex 5, France; UNICAEN, COMETE, 14032 Caen, France; Inserm, U 1075 COMETE, 14032 Caen, France.

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http://dx.doi.org/10.1016/j.jbspin.2016.11.006DOI Listing
May 2017

Vitamin D metabolite profiling using liquid chromatography-tandem mass spectrometry (LC-MS/MS).

J Steroid Biochem Mol Biol 2016 11 26;164:110-114. Epub 2015 Sep 26.

Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario K7L3N6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2015.09.026DOI Listing
November 2016

Vitamin D metabolism in the premature newborn: A randomized trial.

Clin Nutr 2016 08 13;35(4):835-41. Epub 2015 Aug 13.

University of Nebraska Medical Center, Pediatrics, 981205 Nebraska Medical Center, Omaha, NE 68198-1205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2015.07.023DOI Listing
August 2016

Impact of Vitamin D Supplementation on Gross Motor Development of Healthy Term Infants: A Randomized Dose-Response Trial.

Phys Occup Ther Pediatr 2016 Aug 1;36(3):330-42. Epub 2015 Sep 1.

c School of Dietetics and Human Nutrition , McGill University , Ste. Anne de Bellevue, Quebec , Canada.

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http://dx.doi.org/10.3109/01942638.2015.1050150DOI Listing
August 2016

Dynamics of Vitamin D Metabolism in Maternal-Fetal Dyads.

J Pediatr Gastroenterol Nutr 2016 Mar;62(3):486-90

*College of Allied Health Professions, Medical Nutrition Education, 984045 Nebraska Medical Center †Pediatrics, 981205 Nebraska Medical Center ‡College of Public Health, 984375 Nebraska Medical Center, University of Nebraska Medical Center, Omaha §Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.

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http://pdfs.journals.lww.com/jpgn/2016/03000/Dynamics_of_Vit
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPG.0000000000001001DOI Listing
March 2016

A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice.

Endocrinology 2015 Dec 6;156(12):4388-97. Epub 2015 Oct 6.

Department of Biomedical and Molecular Sciences (M.K., G.J.), Queen's University, Kingston, Ontario, Canada K7L3N6; and Department of Biochemistry (S.M.L., J.W.P.), University of Wisconsin-Madison, Madison, Wisconsin 53706.

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http://dx.doi.org/10.1210/en.2015-1664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655220PMC
December 2015

Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations.

J Clin Endocrinol Metab 2015 Aug 22;100(8):2832-6. Epub 2015 Jun 22.

Division of Endocrinology, Department of Medicine (A.D.S., E.C.H., D.S., I.B.K.), Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences (B.O., K.S.), and Division of Medical Genetics, Department of Medicine (R.N.), University of California, San Francisco, San Francisco, California 94143; Division of Endocrinology and Metabolism (M.Kr., S.B.-P.), Medical University of Vienna, A-1090 Vienna, Austria; Department of Biomedical and Molecular Sciences (M.Ka., G.J.), Queen's University, Kingston, Ontario, Canada K7L 3N6; Endocrine Research Unit (D.D.B., Y.M., D.S.), San Francisco Department of Veterans Affairs Medical Center; San Francisco, California 94121; and Redwood Renal Associates (A.S.M.), Eureka, California 95501.

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http://dx.doi.org/10.1210/jc.2015-1973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524985PMC
August 2015

Interpreting vitamin D assay results: proceed with caution.

Authors:
Glenville Jones

Clin J Am Soc Nephrol 2015 Feb 8;10(2):331-4. Epub 2014 Aug 8.

Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario Canada

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http://dx.doi.org/10.2215/CJN.05490614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317739PMC
February 2015

Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD.

J Clin Endocrinol Metab 2014 Jul 26;99(7):2567-74. Epub 2014 Mar 26.

Department of Biomedical and Molecular Sciences (M.Ka., G.J.), Queen's University, Kingston, Ontario, Canada K7L 3N6; Bone Metabolism Unit (J.C.G.), Creighton University School of Medicine, Omaha, Nebraska 68131; Indiana University School of Medicine (M.P.), Indianapolis, Indiana 46202-5250; Department of General Pediatrics, (K-P. S., M.Ko.) University Children's Hospital, D-48149, Münster, Germany; Department of Biochemistry (H.F.D.), University of Wisconsin-Madison, Madison, Wisconsin 53706; Departmento de Quimica Organica (R.S., B.L., A.M., M.M.), Laboratorio Ignacio Ribas, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain; McGill University and Shriners Hospital for Children-Canada (R.S.), Montréal, Québec, Canada H3G 1A6; Endocrine Unit (J.S.F.), Massachusetts General Hospital, Boston Massachusetts 02114; and Health Sciences Research, Waters Corporation (D.P.C), Stamford Avenue, Altrincham Rd, Wilmslow, SK9 4AX United Kingdom.

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http://dx.doi.org/10.1210/jc.2013-4388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079315PMC
July 2014

UV and dietary predictors of serum 25-hydroxyvitamin D concentrations among young shift-working nurses and implications for bone density and skin cancer.

Public Health Nutr 2014 Apr 9;17(4):772-9. Epub 2013 Jul 9.

1 Department of Community Health and Epidemiology, Cancer Research Institute, Queen's University, Kingston, ON K7L 3N6, Canada.

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http://dx.doi.org/10.1017/S1368980013001754DOI Listing
April 2014

Methodological issues in assessing plasma 25-hydroxyvitamin D concentration in newborn infants.

Bone 2014 Apr 25;61:186-90. Epub 2014 Jan 25.

School of Dietetics and Human Nutrition, McGill University, Montréal, Québec, Canada; Montréal Children's Hospital, McGill University Health Centre, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2014.01.012DOI Listing
April 2014

A lifetime of hypercalcemia and hypercalciuria, finally explained.

J Clin Endocrinol Metab 2014 Mar 13;99(3):708-12. Epub 2014 Jan 13.

Division of Endocrinology (T.P.J., J.P.B.), Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032; Department of Biomedical and Molecular Sciences (M.K., G.J.), Queen's University, Kingston, Ontario, Canada K7L 3N6; Nephology Research (R.K.), Departments of Medicine, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55902; Department of General Pediatrics (K.-P.S.), University Children's Hospital, 48129 Munster, Germany; and School of Environmental and Biological Sciences (S.S.), Rutgers University, New Brunswick, New Jersey 08901.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2013-3802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942238PMC
March 2014

Extrarenal vitamin D activation and interactions between vitamin D₂, vitamin D₃, and vitamin D analogs.

Authors:
Glenville Jones

Annu Rev Nutr 2013 29;33:23-44. Epub 2013 Apr 29.

Department of Biomedical & Molecular Sciences, Queen's University, Kingston, Ontario, Canada K7L 3N6.

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http://dx.doi.org/10.1146/annurev-nutr-071812-161203DOI Listing
February 2014

Cytochrome P450-mediated metabolism of vitamin D.

J Lipid Res 2014 Jan 6;55(1):13-31. Epub 2013 Apr 6.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1194/jlr.R031534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927478PMC
January 2014

CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo.

Proc Natl Acad Sci U S A 2013 Sep 9;110(39):15650-5. Epub 2013 Sep 9.

Department of Biochemistry, University of Wisconsin, Madison, WI 53706.

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http://dx.doi.org/10.1073/pnas.1315006110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785760PMC
September 2013

Metabolism and biomarkers of vitamin D.

Authors:
Glenville Jones

Scand J Clin Lab Invest Suppl 2012 ;243:7-13

Department of Biomedical & Molecular Sciences, Department of Medicine, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.3109/00365513.2012.681892DOI Listing
August 2012

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D.

Arch Biochem Biophys 2012 Jul 12;523(1):9-18. Epub 2011 Nov 12.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada K7L 3N6.

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http://dx.doi.org/10.1016/j.abb.2011.11.003DOI Listing
July 2012

Functional properties and substrate characterization of human CYP26A1, CYP26B1, and CYP26C1 expressed by recombinant baculovirus in insect cells.

J Pharmacol Toxicol Methods 2011 Nov-Dec;64(3):258-63. Epub 2011 Aug 31.

Cytochroma, Inc., 100 Allstate Parkway, Suite 600, Markham, Ontario, Canada L3R 6H3.

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http://dx.doi.org/10.1016/j.vascn.2011.08.005DOI Listing
June 2012

Vitamin D analogs.

Authors:
Glenville Jones

Rheum Dis Clin North Am 2012 Feb;38(1):207-32, xi

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1016/j.rdc.2012.03.016DOI Listing
February 2012

Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement.

Immunobiology 2011 Sep 7;216(9):988-96. Epub 2011 Apr 7.

Department of Microbiology and Immunology, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1016/j.imbio.2011.03.011DOI Listing
September 2011

Bioengineering anabolic vitamin D-25-hydroxylase activity into the human vitamin D catabolic enzyme, cytochrome P450 CYP24A1, by a V391L mutation.

J Biol Chem 2011 Aug 22;286(33):28729-37. Epub 2011 Jun 22.

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6.

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http://dx.doi.org/10.1074/jbc.M111.236679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190681PMC
August 2011

CYP24A1 and kidney disease.

Curr Opin Nephrol Hypertens 2011 Jul;20(4):337-44

Division of Cancer Biology and Genetics, Cancer Research Institute, Department of Biochemistry, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1097/MNH.0b013e3283477a7bDOI Listing
July 2011

Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones.

Eur J Med Chem 2010 Oct 8;45(10):4427-34. Epub 2010 Jul 8.

Medicinal Chemistry, Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK.

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http://dx.doi.org/10.1016/j.ejmech.2010.07.001DOI Listing
October 2010

Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides.

Bioorg Med Chem 2010 Jul 9;18(14):4939-46. Epub 2010 Jun 9.

Medicinal Chemistry, Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK.

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http://dx.doi.org/10.1016/j.bmc.2010.06.011DOI Listing
July 2010

Vitamin D analogs.

Authors:
Glenville Jones

Endocrinol Metab Clin North Am 2010 Jun;39(2):447-72, table of contents

Department of Biochemistry Queen's University, Kingston, Ontario, Canada K7L 3N6.

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http://dx.doi.org/10.1016/j.ecl.2010.02.003DOI Listing
June 2010

Pharmacokinetics of vitamin D toxicity.

Authors:
Glenville Jones

Am J Clin Nutr 2008 Aug;88(2):582S-586S

Departments of Biochemistry and Medicine, Queen's University, Kingston, Ontario, Canada.

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https://academic.oup.com/ajcn/article/88/2/582S/4650129
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http://dx.doi.org/10.1093/ajcn/88.2.582SDOI Listing
August 2008

Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect.

Proc Natl Acad Sci U S A 2008 Jul 7;105(28):9540-5. Epub 2008 Jul 7.

Departments of Biology, Biochemistry, Pathology, and Medicine, Queen's University, Kingston, ON, Canada K7L 3N6.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0712132105
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http://dx.doi.org/10.1073/pnas.0712132105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474474PMC
July 2008

Structural analysis of CYP2R1 in complex with vitamin D3.

J Mol Biol 2008 Jun 8;380(1):95-106. Epub 2008 Apr 8.

Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jmb.2008.03.065DOI Listing
June 2008

Contemporary diagnosis and treatment of vitamin D-related disorders.

J Bone Miner Res 2007 Dec;22 Suppl 2:V11-5

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1359/jbmr.07s219DOI Listing
December 2007

Selective conversion by microglia of dehydroepiandrosterone to 5-androstenediol-A steroid with inherent estrogenic properties.

J Steroid Biochem Mol Biol 2007 Nov-Dec;107(3-5):156-62. Epub 2007 Jun 22.

Department of Biochemistry, Queen's University, Kingston, Ontario K7L 3N6, Canada.

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http://dx.doi.org/10.1016/j.jsbmb.2007.04.004DOI Listing
November 2007

Expanding role for vitamin D in chronic kidney disease: importance of blood 25-OH-D levels and extra-renal 1alpha-hydroxylase in the classical and nonclassical actions of 1alpha,25-dihydroxyvitamin D(3).

Authors:
Glenville Jones

Semin Dial 2007 Jul-Aug;20(4):316-24

Departments of Biochemistry and Medicine, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1525-139X.2007.00302.xDOI Listing
October 2007

Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1alpha,25-(OH)2D3-26,23-lactone.

Proc Natl Acad Sci U S A 2007 Jul 23;104(31):12673-8. Epub 2007 Jul 23.

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1073/pnas.0702093104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1937525PMC
July 2007

Oxidation of vinyl carbamate and formation of 1,N6-ethenodeoxyadenosine in murine lung.

Drug Metab Dispos 2007 May 12;35(5):713-20. Epub 2007 Feb 12.

Department of Anatomy and Cell Biology, Queen's University, Kingston, Ontario, Canada K7L 3N6.

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http://dx.doi.org/10.1124/dmd.106.013805DOI Listing
May 2007

Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies.

Arch Biochem Biophys 2007 Apr 13;460(2):177-91. Epub 2006 Dec 13.

Department of Biochemistry, Queen's University, Kingston, ON, Canada K7L 3N6.

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http://dx.doi.org/10.1016/j.abb.2006.11.030DOI Listing
April 2007

Promise of vitamin D analogues in the treatment of hyperproliferative conditions.

Mol Cancer Ther 2006 Apr;5(4):797-808

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-05
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http://dx.doi.org/10.1158/1535-7163.MCT-05-0539DOI Listing
April 2006

Metabolism of dehydroepiandrosterone by rodent brain cell lines: relationship between 7-hydroxylation and aromatization.

J Steroid Biochem Mol Biol 2005 Jan;93(1):81-6

Department of Biochemistry, Queen's University Kingston, Ont., Canada K7L 3N6.

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http://dx.doi.org/10.1016/j.jsbmb.2004.11.008DOI Listing
January 2005

Enzymes involved in the activation and inactivation of vitamin D.

Trends Biochem Sci 2004 Dec;29(12):664-73

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6.

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http://ac.els-cdn.com/S0968000404002701/1-s2.0-S096800040400
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http://www.cell.com/trends/biochemical-sciences/pdf/S0968-00
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http://linkinghub.elsevier.com/retrieve/pii/S096800040400270
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http://dx.doi.org/10.1016/j.tibs.2004.10.005DOI Listing
December 2004

Importance of cytochrome P450-mediated metabolism in the mechanism of action of vitamin D analogs.

Recent Results Cancer Res 2003 ;164:189-202

Department of Biochemistry, Queen's University, Kingston, ON K7L 3N6, Canada.

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http://link.springer.com/content/pdf/10.1007/978-3-642-55580
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http://dx.doi.org/10.1007/978-3-642-55580-0_14DOI Listing
December 2003

Vitamin D analogs--drug design based on proteins involved in vitamin D signal transduction.

Curr Drug Targets Immune Endocr Metabol Disord 2003 Mar;3(1):43-66

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6.

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March 2003

HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A.

J Lipid Res 2002 Jul;43(7):1133-42

Department of Biochemistry, Queen's University, Kingston, ON, K7L 3N6, Canada.

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http://www.jlr.org/content/43/7/1133.full.pdf
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http://dx.doi.org/10.1194/jlr.m100343-jlr200DOI Listing
July 2002

Hepatic osteodystrophy in chronic cholestasis: evidence for a multifactorial etiology.

Pediatr Transplant 2002 Apr;6(2):136-40

Pediatric Gastroenterology Division, Children's Hospital, University of Texas Medical Branch, Galveston TX 77555-0352, USA.

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April 2002

1,25(OH)2D, the preferred substrate for CYP24.

J Bone Miner Res 2002 Jan;17(1):179-81

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http://dx.doi.org/10.1359/jbmr.2002.17.1.179DOI Listing
January 2002