Publications by authors named "Glenn M Marshall"

100Publications

A structural view of PA2G4 isoforms with opposing functions in cancer.

J Biol Chem 2020 09 20. Epub 2020 Sep 20.

St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia, Australia.

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http://dx.doi.org/10.1074/jbc.REV120.014293DOI Listing
September 2020

Targeting TSLP-Induced Tyrosine Kinase Signaling Pathways in CRLF2-Rearranged Ph-like ALL.

Mol Cancer Res 2020 Aug 14. Epub 2020 Aug 14.

Children's Cancer Institute, School of Women's and Children's Health, UNSW Sydney, Sydney, Australia.

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http://dx.doi.org/10.1158/1541-7786.MCR-19-1098DOI Listing
August 2020

Prevalence, hospital admissions and costs of child chronic conditions: A population-based study.

J Paediatr Child Health 2020 Sep 5;56(9):1365-1370. Epub 2020 Jun 5.

Child Population and Translational Health Research, Children's Hospital at Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/jpc.14932DOI Listing
September 2020

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.

Cell Rep 2019 11;29(6):1675-1689.e9

Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.09.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880934PMC
November 2019

Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.

J Cancer Res Clin Oncol 2019 Sep 24;145(9):2241-2250. Epub 2019 Jul 24.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, Australia.

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http://dx.doi.org/10.1007/s00432-019-02981-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708510PMC
September 2019

Predictors of Success of Phase II Pediatric Oncology Clinical Trials.

Oncologist 2019 08 26;24(8):e765-e774. Epub 2019 Feb 26.

Children's Cancer Institute, University of New South Wales, Randwick, Australia

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http://dx.doi.org/10.1634/theoncologist.2017-0666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693728PMC
August 2019

Too many targets, not enough patients: rethinking neuroblastoma clinical trials.

Nat Rev Cancer 2018 06;18(6):389-400

Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, Australia.

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http://www.nature.com/articles/s41568-018-0003-x
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http://dx.doi.org/10.1038/s41568-018-0003-xDOI Listing
June 2018

Delineation of the frequency and boundary of chromosomal copy number variations in paediatric neuroblastoma.

Cell Cycle 2018 ;17(6):749-758

a Children's Cancer Institute Australia for Medical Research , University of New South Wales , Sydney , Australia.

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http://dx.doi.org/10.1080/15384101.2017.1421875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969554PMC
September 2019

Discovering cancer vulnerabilities using high-throughput micro-RNA screening.

Nucleic Acids Res 2017 Dec;45(22):12657-12670

The Kinghorn Cancer Centre & Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1093/nar/gkx1072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728403PMC
December 2017

Establishing Australian school re-entry service guidelines for children diagnosed with cancer.

J Paediatr Child Health 2017 06 12;53(6):529-533. Epub 2017 May 12.

Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/jpc.13563DOI Listing
June 2017

The regulatory role of long noncoding RNAs in cancer.

Cancer Lett 2017 04 19;391:12-19. Epub 2017 Jan 19.

Children's Cancer Institute Australia for Medical Research, Randwick, Sydney, NSW 2031, Australia; UNSW Centre for Childhood Cancer Research, UNSW Australia, Kensington, Sydney, NSW 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.01.010DOI Listing
April 2017

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia.

Oncotarget 2016 09;7(37):58728-42

Leukaemia Biology Program, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.18632/oncotarget.11233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312271PMC
September 2016

Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.

Clin Cancer Res 2016 Sep 24;22(17):4391-404. Epub 2016 Mar 24.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2539DOI Listing
September 2016

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

Mol Oncol 2016 06 2;10(6):866-78. Epub 2016 Mar 2.

Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Randwick 2031, Australia; Kids Cancer Centre, Sydney Children's Hospital, Randwick 2031, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423163PMC
June 2016

High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients.

Cancer Lett 2016 May 20;374(2):315-23. Epub 2016 Feb 20.

Children's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales, Randwick 2031, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.02.021DOI Listing
May 2016

Down syndrome and leukemia: insights into leukemogenesis and translational targets.

Transl Pediatr 2015 Apr;4(2):76-92

1 Kids Cancer Centre, Sydney Children's Hospital, Randwick, Australia ; 2 School of Women's and Children's Health, University of New South Wales, Kensington, Australia ; 3 Children's Cancer Institute Australia, University of New South Wales, Lowy Cancer Centre, Randwick, Australia.

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http://dx.doi.org/10.3978/j.issn.2224-4336.2015.03.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729084PMC
April 2015

The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects.

Clin Cancer Res 2016 05 5;22(10):2534-44. Epub 2016 Jan 5.

Children's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales Australia, Randwick, New South Wales, Australia. School of Women's & Children's Health, University of New South Wales Australia, Randwick, New South Wales, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1666DOI Listing
May 2016

WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.

Cancer Res 2015 Dec 15;75(23):5143-54. Epub 2015 Oct 15.

Children's Cancer Institute Australia, Randwick, Sydney, New South Wales, Australia. School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Randwick, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0423DOI Listing
December 2015

Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma.

Mol Oncol 2015 Aug 29;9(7):1484-500. Epub 2015 Apr 29.

Children's Cancer Institute Australia, University of New South Wales, Sydney, Australia; Kids Cancer Centre, Sydney Children's Hospital, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528804PMC
August 2015

Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance.

Exp Hematol 2015 Jan 29;43(1):32-43.e1-35. Epub 2014 Oct 29.

Division of Hematology and Oncology, Cedars Sinai Medical Center, University of California, Los Angeles, School of Medicine, Los Angeles, CA, United States; National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1016/j.exphem.2014.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894481PMC
January 2015

Paternal intake of folate and vitamins B6 and B12 before conception and risk of childhood acute lymphoblastic leukemia.

Cancer Causes Control 2014 Dec 5;25(12):1615-25. Epub 2014 Oct 5.

Section of Environment and Radiation, International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, 69372, Lyon Cedex 08, France,

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http://link.springer.com/content/pdf/10.1007/s10552-014-0466
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http://link.springer.com/10.1007/s10552-014-0466-3
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http://dx.doi.org/10.1007/s10552-014-0466-3DOI Listing
December 2014

Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression.

J Natl Cancer Inst 2014 Jul 6;106(7). Epub 2014 Jun 6.

Affiliations of authors: Children's Cancer Institute Australia for Medical Research, Randwick NSW, Australia (PYL, GMM, AET, MW, BL, BBC, MK, TL); Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy (DE, GM, GP); Kids Cancer Centre, Sydney Children's Hospital, Randwick NSW, Australia (GMM); Department of Pathology and Inflammation and Infection Research Centre, University of New South Wales, Kensington 2052, Australia (PP); Institute of Molecular Medicine, Martin Luther University, ZAMED, Halle, Germany (JLB, SH); School of Medicine and Public Health, Priority Research Centre for Cancer Research, University of Newcastle, Callaghan NSW, Australia (XDZ); Harry Perkins Institute of Medical Research, Centre for Medical Research, University of Western Australia, Nedlands WA, Australia (AF); Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst NSW, Australia (AS); St Vincent's Clinical School, University of New South Wales, Darlinghurst NSW, Australia (AS, JSM, MED); Australian Centre for Nanomedicine, Randwick NSW, Australia (MK); Garvan Institute of Medical Research, Darlinghurst NSW, Australia (AS, JSM, MED); School of Women's & Children's Health, University of New South Wales, Randwick NSW, Australia (TL).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/dju113DOI Listing
July 2014

Molecular profiling of childhood cancer: Biomarkers and novel therapies.

BBA Clin 2014 Jun 28;1:59-77. Epub 2014 Jun 28.

Children's Cancer Research Unit, Kids Research Institute, Westmead 2145, New South Wales, Australia ; The University of Sydney Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, Westmead 2145, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.bbacli.2014.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633945PMC
June 2014

The prenatal origins of cancer.

Nat Rev Cancer 2014 04 6;14(4):277-89. Epub 2014 Mar 6.

Department of Neurology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nrc3679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041218PMC
April 2014

The novel long noncoding RNA linc00467 promotes cell survival but is down-regulated by N-Myc.

PLoS One 2014 19;9(2):e88112. Epub 2014 Feb 19.

Children's Cancer Institute Australia for Medical Research, Randwick, Sydney, Australia ; School of Women's & Children's Health, UNSW Medicine, University of New South Wales, Randwick, Sydney, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088112PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929584PMC
December 2014

TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization.

Cell Cycle 2013 Mar 19;12(6):889-98. Epub 2013 Feb 19.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, Randwick, NSW Australia.

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http://www.tandfonline.com/doi/abs/10.4161/cc.23825
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http://dx.doi.org/10.4161/cc.23825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637347PMC
March 2013

Synthesis of retinoid enhancers based on 2-aminobenzothiazoles for anti-cancer therapy.

Bioorg Med Chem 2012 Dec 3;20(23):6877-84. Epub 2012 Oct 3.

School of Chemistry, The University of New South Wales, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.bmc.2012.09.035DOI Listing
December 2012

Prognostic significance of promoter DNA methylation in patients with childhood neuroblastoma.

Clin Cancer Res 2012 Oct 28;18(20):5690-700. Epub 2012 Aug 28.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, Randwick, NSW, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-0294DOI Listing
October 2012

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.

PLoS One 2012 21;7(5):e37470. Epub 2012 May 21.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, Randwick, New South Wales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037470PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357404PMC
December 2012

Enhancing the anticancer effect of the histone deacetylase inhibitor by activating transglutaminase.

Eur J Cancer 2012 Nov 27;48(17):3278-87. Epub 2012 Mar 27.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1016/j.ejca.2012.02.067DOI Listing
November 2012

N-Myc regulates expression of the detoxifying enzyme glutathione transferase GSTP1, a marker of poor outcome in neuroblastoma.

Cancer Res 2012 Feb 27;72(4):845-53. Epub 2011 Dec 27.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, Randwick, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1885DOI Listing
February 2012

ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.

J Natl Cancer Inst 2011 Aug 28;103(16):1236-51. Epub 2011 Jul 28.

Experimental Therapeutics and Molecular Diagnostics Program, Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, P.O. Box 81, Randwick, NSW 2031, Australia.

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http://dx.doi.org/10.1093/jnci/djr256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156802PMC
August 2011

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

Pharmacogenet Genomics 2011 May;21(5):270-9

Children's Cancer Institute Australia for Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1097/FPC.0b013e328343dd5fDOI Listing
May 2011

Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target.

Cancer Res 2010 Apr 16;70(7):2749-58. Epub 2010 Mar 16.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848992PMC
April 2010

MYCN oncoprotein targets and their therapeutic potential.

Cancer Lett 2010 Jul 13;293(2):144-57. Epub 2010 Feb 13.

Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom.

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http://dx.doi.org/10.1016/j.canlet.2010.01.015DOI Listing
July 2010

Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation.

J Biol Chem 2010 Feb 10;285(6):3561-7. Epub 2009 Dec 10.

Children's Cancer Institute Australia, Sydney Children's Hospital, Sydney, New South Wales 2031, Australia.

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http://dx.doi.org/10.1074/jbc.M109.053041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823496PMC
February 2010

The cyclin-dependent kinase inhibitor, p21(WAF1), promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells.

Carcinogenesis 2009 Nov 22;30(11):1865-71. Epub 2009 Sep 22.

Children's Cancer Institute Australia for Medical Research, University of New South Wales, Sydney 2031, Australia.

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http://dx.doi.org/10.1093/carcin/bgp225DOI Listing
November 2009

Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors.

Eur J Cancer 2009 Jul 1;45(10):1846-54. Epub 2009 Apr 1.

Children's Cancer Institute Australia for Medical Research, University of New South Wales, Sydney, NSW, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490900172
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http://dx.doi.org/10.1016/j.ejca.2009.03.002DOI Listing
July 2009

The critical role of the class III histone deacetylase SIRT1 in cancer.

Cancer Res 2009 Mar 24;69(5):1702-5. Epub 2009 Feb 24.

Children's Cancer Institute Australia for Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3365DOI Listing
March 2009

Rapamycin treatment for a child with germline PTEN mutation.

Nat Clin Pract Oncol 2008 Jun 22;5(6):357-61. Epub 2008 Apr 22.

Kolling Institute of Medical Research, University of Sydney and Royal North Shore Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1038/ncponc1112DOI Listing
June 2008

Mechanism of relapse in pediatric acute lymphoblastic leukemia.

Cell Cycle 2008 May 29;7(10):1315-20. Epub 2008 Feb 29.

Children's Cancer Institute Australiafor Medical Research, Experimental Therapeutics Program, PO Box 81 (HighSt), Randwick, Sydney, NSW 2031 Australia.

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http://dx.doi.org/10.4161/cc.7.10.5885DOI Listing
May 2008

Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis.

Proc Natl Acad Sci U S A 2007 Nov 14;104(47):18682-7. Epub 2007 Nov 14.

Children's Cancer Institute Australia for Medical Research and Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, High Street, Randwick, Sydney, New South Wales 2031, Australia.

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http://dx.doi.org/10.1073/pnas.0705524104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141837PMC
November 2007