Glenda M Halliday

Glenda M Halliday

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Glenda M Halliday

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Heritability in frontotemporal tauopathies.

Alzheimers Dement (Amst) 2019 Dec 24;11:115-124. Epub 2019 Jan 24.

Faculty of Medicine and Health, Charles Perkins Centre and Discipline of Pathology, University of Sydney, Sydney, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S23528729183008
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http://dx.doi.org/10.1016/j.dadm.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351353PMC
December 2019

Cellular and regional vulnerability in frontotemporal tauopathies.

Acta Neuropathol 2019 Nov 15;138(5):705-727. Epub 2019 Jun 15.

Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, University of Sydney, 94 Mallet Street, Camperdown, Sydney, NSW, 2050, Australia.

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http://dx.doi.org/10.1007/s00401-019-02035-7DOI Listing
November 2019

TDP-43 levels in the brain tissue of ALS cases with and without or gene expansions.

Neurology 2019 Nov 16;93(19):e1748-e1755. Epub 2019 Oct 16.

From the University of Sydney (Y.Y., G.M.H., M.C.K., R.H.T.), Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health; School of Medical Sciences (G.M.H., R.H.T.), University of New South Wales; Neuroscience Research Australia (G.M.H., R.H.T.); and Department of Neurology (M.C.K.), Royal Prince Alfred Hospital, Sydney, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000008439DOI Listing
November 2019

Expression of tyrosine hydroxylase isoforms and phosphorylation at serine 40 in the human nigrostriatal system in Parkinson's disease.

Neurobiol Dis 2019 10 2;130:104524. Epub 2019 Jul 2.

School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, The University of Newcastle, Callaghan, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104524DOI Listing
October 2019

Alpha-synuclein: prion or prion-like?

Acta Neuropathol 2019 Oct 12;138(4):509-514. Epub 2019 Aug 12.

Brain and Mind Centre and Central Clinical School, University of Sydney, Sydney, NSW, 2050, Australia.

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http://dx.doi.org/10.1007/s00401-019-02057-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778512PMC
October 2019

Letter to the Editor.

J Neuropathol Exp Neurol 2019 Oct;78(10):975-977

Sydney Brain Bank, Neuroscience Research Australia, Randwick, Australia.

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http://dx.doi.org/10.1093/jnen/nlz069DOI Listing
October 2019

Cognitive fluctuations in Lewy body dementia: towards a pathophysiological framework.

Brain 2019 Oct 15. Epub 2019 Oct 15.

Central Clinical School, Faculty of Medicine and Health, University of Sydney, NSW Australia.

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http://dx.doi.org/10.1093/brain/awz311DOI Listing
October 2019

Clinical features of Lewy body dementia: insights into diagnosis and pathophysiology.

J Neurol 2019 Oct 24. Epub 2019 Oct 24.

Parkinson's Disease Research Clinic, L2 Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, 97 Church Street, Camperdown, Sydney, NSW, 2050, Australia.

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http://dx.doi.org/10.1007/s00415-019-09583-8DOI Listing
October 2019

Evaluating the Sustained Attention Response Task to Quantify Cognitive Fluctuations in Dementia With Lewy Bodies.

J Geriatr Psychiatry Neurol 2019 Oct 31:891988719882093. Epub 2019 Oct 31.

Faculty of Medicine and Health, Brain and Mind Centre and Central Clinical School, University of Sydney, Camperdown, Sydney, Australia.

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http://dx.doi.org/10.1177/0891988719882093DOI Listing
October 2019

Impaired Color Discrimination-A Specific Marker of Hallucinations in Lewy Body Disorders.

J Geriatr Psychiatry Neurol 2019 Sep 29;32(5):257-264. Epub 2019 Apr 29.

1 Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, University of Sydney, Camperdown, Sydney, Australia.

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http://dx.doi.org/10.1177/0891988719845501DOI Listing
September 2019

Subtle gait and balance impairments occur in idiopathic rapid eye movement sleep behavior disorder.

Mov Disord 2019 Sep 26;34(9):1374-1380. Epub 2019 Jun 26.

ForeFront Research Team, Brain and Mind Centre, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1002/mds.27780DOI Listing
September 2019

Neuroinflammation in frontotemporal dementia.

Nat Rev Neurol 2019 Sep 19;15(9):540-555. Epub 2019 Jul 19.

School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1038/s41582-019-0231-zDOI Listing
September 2019

Autophagy activation promotes clearance of α-synuclein inclusions in fibril-seeded human neural cells.

J Biol Chem 2019 Sep 2;294(39):14241-14256. Epub 2019 Aug 2.

ForeFront Dementia and Movement Disorders Laboratory, Brain and Mind Centre, Central Clinical School, Faculty of Medicine and Health, University of Sydney, Camperdown, New South Wales 2050, Australia

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http://dx.doi.org/10.1074/jbc.RA119.008733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768637PMC
September 2019

Heritability and genetic variance of dementia with Lewy bodies.

Neurobiol Dis 2019 07 3;127:492-501. Epub 2019 Apr 3.

Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588425PMC
July 2019

Increased Tau Phosphorylation in Motor Neurons From Clinically Pure Sporadic Amyotrophic Lateral Sclerosis Patients.

J Neuropathol Exp Neurol 2019 Jul;78(7):605-614

School of Chemistry and Molecular Bioscience, University of Wollongong.

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http://dx.doi.org/10.1093/jnen/nlz041DOI Listing
July 2019

Cross-examining candidate genes implicated in multiple system atrophy.

Acta Neuropathol Commun 2019 Jul 24;7(1):117. Epub 2019 Jul 24.

Brain and Mind Centre & Central Clinical School, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1186/s40478-019-0769-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651992PMC
July 2019

Parkinson's progression prediction using machine learning and serum cytokines.

NPJ Parkinsons Dis 2019 25;5:14. Epub 2019 Jul 25.

ForeFront Dementia and Movement Disorders Laboratory, Brain and Mind Centre, Central Clinical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW 2050 Australia.

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http://dx.doi.org/10.1038/s41531-019-0086-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658482PMC
July 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Jun 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson's disease.

Brain 2019 Jun;142(6):1690-1700

Department of Neurological Sciences, Rush University Medical Center, Chicago Illinois, USA.

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http://dx.doi.org/10.1093/brain/awz104DOI Listing
June 2019

Coexisting Lewy body disease and clinical parkinsonism in frontotemporal lobar degeneration.

Neurology 2019 May 24;92(21):e2472-e2482. Epub 2019 Apr 24.

From the Discipline of Pathology (S.L.F., D.R.C., A.S., C.V.M., J.J.K.), Central Clinical School (J.B.K., W.S.K., E.J., R.H.T., J.R.H., G.M.H.), Faculty of Medicine and Health, Brain and Mind Centre (J.B.K., W.S.K., E.J., R.H.T., O.P., J.R.H., G.M.H.), and School of Psychology (O.P.), The University of Sydney; Neuroscience Research Australia (H.M., C.E.S., A.B.M., A.J.A., F.C.-J., L.B., J.B.K., W.S.K., E.J., R.H.T., O.P., J.R.H., G.M.H.), Sydney; School of Medical Sciences (C.E.S., A.J.A., F.C.-J., J.B.K., W.S.K., R.H.T., G.M.H.), University of New South Wales; and ARC Centre of Excellence in Cognition and its Disorders (O.P., J.R.H.), Sydney, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000007530DOI Listing
May 2019

Brain Banking for Research into Neurodegenerative Disorders and Ageing.

Neurosci Bull 2019 Apr 2;35(2):283-288. Epub 2019 Jan 2.

Neuroscience Research Australia and the University of New South Wales, Sydney, Australia.

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http://link.springer.com/10.1007/s12264-018-0326-3
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http://dx.doi.org/10.1007/s12264-018-0326-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426907PMC
April 2019

Dopamine depletion alters macroscopic network dynamics in Parkinson's disease.

Brain 2019 Apr;142(4):1024-1034

Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1093/brain/awz034DOI Listing
April 2019

A comprehensive screening of copy number variability in dementia with Lewy bodies.

Neurobiol Aging 2019 03 24;75:223.e1-223.e10. Epub 2018 Oct 24.

Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183038
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541211PMC
March 2019

LRRK2-mediated Rab10 phosphorylation in immune cells from Parkinson's disease patients.

Mov Disord 2019 03 30;34(3):406-415. Epub 2018 Dec 30.

Brain and Mind Centre, Central Clinical School, University of Sydney, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1002/mds.27601DOI Listing
March 2019

Gut-brain axis and the spread of α-synuclein pathology: Vagal highway or dead end?

Mov Disord 2019 03 17;34(3):307-316. Epub 2019 Jan 17.

Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Toronto, Canada.

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http://dx.doi.org/10.1002/mds.27556DOI Listing
March 2019

The underacknowledged PPA-ALS: A unique clinicopathologic subtype with strong heritability.

Neurology 2019 Mar 15;92(12):e1354-e1366. Epub 2019 Feb 15.

From the Brain and Mind Centre and Central Clinical School (R.H.T., B.G., C.D.-S., J.B.J.K., M.C.K., J.R.H., G.M.H.) and School of Medical Sciences (J.J.K.), Faculty of Medicine and Health, and Brain and Mind Centre and School of Psychology (O.P.), The University of Sydney; School of Medical Sciences (R.H.T., C.D.-S., G.M.H.), University of New South Wales & Neuroscience Research Australia; Department of Neurology (M.C.K.), Royal Prince Alfred Hospital; ARC Centre of Excellence in Cognition and its Disorders (J.R.H., O.P.); and Division of Neuroscience (B.G.), Garvan Institute of Medical Research and St Vincent's Clinical School, UNSW Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000007146DOI Listing
March 2019

Aphasia in Progressive Supranuclear Palsy: As Severe as Progressive Non-Fluent Aphasia.

J Alzheimers Dis 2018 ;61(2):705-715

Brain and Mind Centre, University of Sydney Medical School, Sydney, Australia.

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http://dx.doi.org/10.3233/JAD-170743DOI Listing
January 2019

Apolipoprotein D Upregulation in Alzheimer's Disease but Not Frontotemporal Dementia.

J Mol Neurosci 2019 Jan 22;67(1):125-132. Epub 2018 Nov 22.

Central Clinical School and Brain and Mind Centre, Faculty of Medicine and Health Sciences, The University of Sydney, 94 Mallet Street, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1007/s12031-018-1217-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344390PMC
January 2019

Von Economo Neurons in Behavioral Variant Frontotemporal Dementia with Underlying Alzheimer's Disease.

J Alzheimers Dis 2019 ;69(4):963-967

The University of Sydney, Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, Australia.

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http://dx.doi.org/10.3233/JAD-180900DOI Listing
January 2019

Nigrostriatal pathology with reduced astrocytes in LRRK2 S910/S935 phosphorylation deficient knockin mice.

Neurobiol Dis 2018 12 5;120:76-87. Epub 2018 Sep 5.

Central Clinical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW 2050, Australia; School of Medical Sciences, Faculty of Medicine, University of New South Wales, Kensington, NSW 2033, Australia; Neuroscience Research Australia, Randwick, NSW 2031, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197399PMC
December 2018

Impact of small vessel disease on severity of motor and cognitive impairment in Parkinson's disease.

J Clin Neurosci 2018 Dec 14;58:70-74. Epub 2018 Oct 14.

University of Sydney, Faculty of Medicine and Health, School of Medical Sciences, Discipline of Pathology, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2018.10.029DOI Listing
December 2018

Clinical Aspects of Alzheimer's Disease.

Adv Neurobiol 2017 ;15:31-53

School of Psychology, Central Medical School and Brain & Mind Centre, University of Sydney, Mallett St, Sydney, 2006, NSW, Australia.

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http://dx.doi.org/10.1007/978-3-319-57193-5_2DOI Listing
November 2018

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.

Brain 2018 10;141(10):2895-2907

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/brain/awy238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158742PMC
October 2018

Reply: Will FTLD-tau work for all when FTDP-17 retires?

Brain 2018 08;141(8):e63

Brain and Mind Centre and Central Clinical School, Faculty of Medicine and Health, University of Sydney, Australia.

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http://dx.doi.org/10.1093/brain/awy179DOI Listing
August 2018

Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.

Am J Pathol 2018 06 22;188(6):1447-1456. Epub 2018 Mar 22.

Motor Neuron Disease Unit, Department of Anatomy, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.03.002DOI Listing
June 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181PMC
June 2018

von Economo Neuron Density and Thalamus Volumes in Behavioral Deficits in Frontotemporal Dementia Cases with and without a C9ORF72 Repeat Expansion.

J Alzheimers Dis 2017 ;58(3):701-709

Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, Australia.

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/JAD-170002DOI Listing
March 2018

Lipidomics Analysis of Behavioral Variant Frontotemporal Dementia: A Scope for Biomarker Development.

Front Neurol 2018 28;9:104. Epub 2018 Feb 28.

Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fneur.2018.00104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835505PMC
February 2018

MSA prions exhibit remarkable stability and resistance to inactivation.

Acta Neuropathol 2018 01 28;135(1):49-63. Epub 2017 Aug 28.

Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1007/s00401-017-1762-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756500PMC
January 2018

Accumulation of dysfunctional SOD1 protein in Parkinson's disease is not associated with mutations in the SOD1 gene.

Acta Neuropathol 2018 01 19;135(1):155-156. Epub 2017 Oct 19.

Discipline of Biomedical Science and Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.

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http://dx.doi.org/10.1007/s00401-017-1779-6DOI Listing
January 2018

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

Lancet Neurol 2018 01 16;17(1):64-74. Epub 2017 Dec 16.

UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30400-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805394PMC
January 2018

Calcium, mitochondrial dysfunction and slowing the progression of Parkinson's disease.

Exp Neurol 2017 12 2;298(Pt B):202-209. Epub 2017 Aug 2.

Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.expneurol.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037988PMC
December 2017

Deletion of Alzheimer's Disease Risk Gene ABCA7 Alters White Adipose Tissue Development and Leptin Levels.

J Alzheimers Dis Rep 2017 Dec 16;1(1):237-247. Epub 2017 Dec 16.

Brain and Mind Centre, Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.

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http://dx.doi.org/10.3233/ADR-170029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159609PMC
December 2017

The neural correlates and clinical characteristics of psychosis in the frontotemporal dementia continuum and the expansion.

Neuroimage Clin 2017 2;13:439-445. Epub 2016 Dec 2.

Neuroscience Research Australia, Barker Street, Sydney, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia; ARC Centre of Excellence in Cognition and its Disorders, Macquarie University, Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1016/j.nicl.2016.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233794PMC
November 2017

Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain.

Metallomics 2017 10;9(10):1447-1455

Discipline of Biomedical Science and Brain and Mind Centre, Sydney Medical School, The University of Sydney, Camperdown, NSW 2006, Australia.

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http://dx.doi.org/10.1039/c7mt00244kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647261PMC
October 2017

Parkinson's Disease Is Not Simply a Prion Disorder.

J Neurosci 2017 10;37(41):9799-9807

Brain and Mind Centre, Sydney Medical School, University of Sydney, Sydney, 2006 New South Wales, Australia, and.

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http://dx.doi.org/10.1523/JNEUROSCI.1787-16.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637112PMC
October 2017

α-Synuclein Regulates Neuronal Cholesterol Efflux.

Molecules 2017 Oct 19;22(10). Epub 2017 Oct 19.

Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney NSW 2050, Australia.

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http://dx.doi.org/10.3390/molecules22101769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151759PMC
October 2017

Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.

Acta Neuropathol Commun 2017 10 27;5(1):76. Epub 2017 Oct 27.

Brain and Mind Centre, Sydney Medical School, The University of Sydney, 94 Mallett Street, Camperdown, NSW, 2050, Australia.

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http://dx.doi.org/10.1186/s40478-017-0480-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658959PMC
October 2017

Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).

J Neuropathol Exp Neurol 2017 Jul;76(7):605-619

Institute of Neurology, Medical University of Vienna, Vienna, Austria; Center for Neurodegenerative Disease Research, Institute on Aging and Department of Pathology and Laboratory Medicine of the Perelman School of Medicine at the University of Pennsylvania; and Department of Biostatistics and Epidemiology; and Department of Neurosurgery, Center for Brain Injury and Repair, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK; Department of Neuropathology, Institute of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida; Northwestern University Feinberg School of Medicine, Northwestern ADC Neuropathology Core, Chicago, Illinois; Clinical Neuropathology, King's College Hospital and London Neurodegenerative Brain Bank, London, UK; Institute of Neuropathology, University Hospital Zurich, Zurich, Switzerland; University of California San Francisco, Institute for Neurodegenerative Diseases, San Francisco, California; Neuropathology Department, Hôpital de La Salpetrière, AP-HP, UPMC-Sorbonne-University, Paris, France; Institute of Neuropathology, Bellvitge University Hospital, University of Barcelona, CIBERNED, Hospitalet de Llobregat, Barcelona, Spain; Discipline of Pathology, Sydney Medical School, The University of Sydney, Sydney, Australia; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Institut d'Investigacions Biomediques Pi i, Barcelona, Spain; Department of Medicine, Imperial College London, London, UK; IRCCS Foundation "Carlo Besta" Neurological Institute, Milan, Italy; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California; Department of Pathology, University of Sao Paulo Medical School, LIM, São Paulo, Brazil; Brain & Mind Centre, Sydney Medical School, The University of Sydney, and UNSW Medicine & NeuRA, Sydney, Australia; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas; Fishberg Department of Neuroscience, Friedman Brain Institute, and Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Neuropathology, John Radcliffe Hospital, Oxford, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Mental Health and Psychiatry, University Hospitals and University of Geneva School of Medicine, Geneva, Switzerland; Institute of Clinical Neurosciences, University of Bristol, Learning & Research Level 2, Southmead Hospital, Bristol, UK; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada; Department of Pathology and Molecular Medicine, Thomayer Hospital, Prague, Czech Republic; Department of Pathology, First Medical Faculty, Charles University, Prague, Czech Republic; Department of Anatomical Pathology, Alfred Hospital , Prahran, Victoria, Australia; Division of Pathology, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Pathology and Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky; Physiopathology in Aging Lab/Brazilian Aging Brain Study Group-LIM22, University of Sao Paulo Medical School, Sao Paulo, Brazil; Behavioral and Cognitive Neurology Unit, Department of Neurology, University of São Paulo , São Paulo, Brazil; Netherlands Brainbank, Amsterdam and Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan; Institute of Neuroanatomy, Centre for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany; Department of Neurodegenerative Diseases and Gerontopsychiatry at the University of Bonn Medical Center, Bonn, Germany; Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan; Department of Neurology, Saitama Medical University International Medical Center, Saitama, Japan; Department of Neuroscience, Katholieke Universiteit-Leuven; and Department of Pathology, Universitaire Ziekenhuizen-Leuven, Leuven, Belgium; Laboratory of Neuropathology, Department of Pathology and Neuropathology, Kepler University Hospital, Medical School, Johannes Kepler University, Linz, Austria; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK; and Department of Pathology and Laboratory Medicine, Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1093/jnen/nlx041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251511PMC
July 2017

Early-life decline in neurogenesis markers and age-related changes of TrkB splice variant expression in the human subependymal zone.

Eur J Neurosci 2017 Jul 7;46(2):1768-1778. Epub 2017 Jul 7.

Schizophrenia Research Laboratory, Neuroscience Research Australia, Margarete Ainsworth Building, 139 Barker Street, Randwick, NSW, 2031, Australia.

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http://dx.doi.org/10.1111/ejn.13623DOI Listing
July 2017

Exploring the Phenotype in Mild Cognitive Impairment to Aid the Prediction of Those at Risk of Transitioning to Parkinson Disease and Dementia With Lewy Bodies.

J Geriatr Psychiatry Neurol 2017 Jul;30(4):196-205

1 Healthy Brain Ageing Program and Parkinson's Disease Research Clinic, Brain and Mind Centre and Charles Perkins Centre, University of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1177/0891988717711451DOI Listing
July 2017

Increased aneuploidy is not a universal feature across α-synucleinopathies.

Mov Disord 2017 03 10;32(3):475-476. Epub 2016 Nov 10.

Neuroscience Research Australia, Randwick, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/mds.26869DOI Listing
March 2017

Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology.

Neurosci Biobehav Rev 2017 Mar 11;74(Pt A):126-138. Epub 2017 Jan 11.

Neuroscience Research Australia, Sydney, Australia; Dementia Research Unit, Department of Anatomy, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2017.01.004DOI Listing
March 2017

Parkinson disease.

Nat Rev Dis Primers 2017 Mar 23;3:17013. Epub 2017 Mar 23.

Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nrdp.2017.13DOI Listing
March 2017

ALS/FTLD: experimental models and reality.

Acta Neuropathol 2017 02 5;133(2):177-196. Epub 2017 Jan 5.

Neuroscience Research Australia, Randwick, NSW, 2031, Australia.

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http://dx.doi.org/10.1007/s00401-016-1666-6DOI Listing
February 2017

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Neurobiol Aging 2017 01 2;49:214.e13-214.e15. Epub 2016 Sep 2.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; Department of Medical Sciences and Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154872PMC
January 2017

Selective neuronal vulnerability in Parkinson disease.

Nat Rev Neurosci 2017 01;18(2):101-113

Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney 2006, Australia.

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http://dx.doi.org/10.1038/nrn.2016.178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564322PMC
January 2017

Neuronal network disintegration: common pathways linking neurodegenerative diseases.

J Neurol Neurosurg Psychiatry 2016 Nov 12;87(11):1234-1241. Epub 2016 May 12.

Sydney Medical School Brain & Mind Centre, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1136/jnnp-2014-308350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099318PMC
November 2016

Characterization of circular RNAs landscape in multiple system atrophy brain.

J Neurochem 2016 11 5;139(3):485-496. Epub 2016 Sep 5.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/jnc.13752DOI Listing
November 2016

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance.

Front Cell Neurosci 2016 2;10:253. Epub 2016 Nov 2.

Department of Neurology and Neuroscience Institute, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai, China.

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http://dx.doi.org/10.3389/fncel.2016.00253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089992PMC
November 2016

Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts.

Front Aging Neurosci 2016 25;8:274. Epub 2016 Nov 25.

Schizophrenia Research Laboratory, Neuroscience Research AustraliaSydney, NSW, Australia; Schizophrenia Research InstituteSydney, NSW, Australia; School of Psychiatry, Faculty of Medicine, University of New South WalesSydney, NSW, Australia.

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http://dx.doi.org/10.3389/fnagi.2016.00274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123444PMC
November 2016

The substantia nigra and ventral tegmental dopaminergic neurons from development to degeneration.

J Chem Neuroanat 2016 Oct 6;76(Pt B):98-107. Epub 2016 Feb 6.

Neuroscience Research Australia, Sydney, NSW 2031, Australia; School of Medical Science, The University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jchemneu.2016.02.001DOI Listing
October 2016

ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain.

J Alzheimers Dis 2016 09;54(2):569-84

Neuroscience Research Australia, Sydney, NSW, Australia.

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http://dx.doi.org/10.3233/JAD-160456DOI Listing
September 2016

The frontotemporal dementia-motor neuron disease continuum.

Lancet 2016 Aug 14;388(10047):919-31. Epub 2016 Mar 14.

Neuroscience Research Australia, Sydney, NSW, Australia; Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)00737-6DOI Listing
August 2016

Expanding the phenotypic associations of globular glial tau subtypes.

Alzheimers Dement (Amst) 2016 8;4:6-13. Epub 2016 Apr 8.

Discipline of Pathology, Sydney Medical School, The University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1016/j.dadm.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949736PMC
August 2016

TDP-43 in the hypoglossal nucleus identifies amyotrophic lateral sclerosis in behavioral variant frontotemporal dementia.

J Neurol Sci 2016 Jul 4;366:197-201. Epub 2016 May 4.

Neuroscience Research Australia, Sydney, Australia; School of Medical Sciences, University of New South Wales, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2016.05.005DOI Listing
July 2016

Increased peripheral inflammation in asymptomatic leucine-rich repeat kinase 2 mutation carriers.

Mov Disord 2016 06 25;31(6):889-97. Epub 2016 Feb 25.

School of Medical Sciences, University of NSW, Kensington, Australia.

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http://dx.doi.org/10.1002/mds.26529DOI Listing
June 2016

MicroRNA-146a suppresses ROCK1 allowing hyperphosphorylation of tau in Alzheimer's disease.

Sci Rep 2016 05 25;6:26697. Epub 2016 May 25.

Department of Neurology &Neuroscience Institute, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1038/srep26697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879631PMC
May 2016

Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia.

Neurobiol Learn Mem 2016 Apr 28;130:34-43. Epub 2016 Jan 28.

Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.nlm.2016.01.007DOI Listing
April 2016

Cerebellar atrophy in Parkinson's disease and its implication for network connectivity.

Brain 2016 Mar 20;139(Pt 3):845-55. Epub 2016 Jan 20.

1 Brain and Mind Research Institute, University of Sydney, Sydney, Australia 5 Neuroscience Research Australia, Sydney, Australia 7 School of Psychology, Stanford University, Palo Alto, CA, USA.

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http://dx.doi.org/10.1093/brain/awv399DOI Listing
March 2016

Distinctive pathological mechanisms involved in primary progressive aphasias.

Neurobiol Aging 2016 Feb 26;38:82-92. Epub 2015 Oct 26.

Department of Pathology, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.017DOI Listing
February 2016

Animal modeling an oligodendrogliopathy--multiple system atrophy.

Acta Neuropathol Commun 2016 Feb 9;4:12. Epub 2016 Feb 9.

Neuroscience Research Australia, Barker St, Randwick, Sydney, NSW, 2031, Australia.

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http://dx.doi.org/10.1186/s40478-016-0279-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748629PMC
February 2016

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy.

Acta Neuropathol 2016 Jan 10;131(1):87-102. Epub 2015 Dec 10.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1007/s00401-015-1509-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879001PMC
January 2016

Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.

Nat Commun 2015 Nov 27;6:8836. Epub 2015 Nov 27.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia.

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http://dx.doi.org/10.1038/ncomms9836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674770PMC
November 2015

The differentiation of progressive supranuclear palsy.

Neurodegener Dis Manag 2015 Oct 28;5(5):385-8. Epub 2015 Oct 28.

Neuroscience Research Australia & University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.2217/nmt.15.37DOI Listing
October 2015