Publications by authors named "Glen J Weiss"

100Publications

Financial Conflicts of Interest Change After a High-Impact Clinical Trial Publication in Oncology.

J Patient Cent Res Rev 2020 27;7(3):249-254. Epub 2020 Jul 27.

Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA.

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July 2020

Predictable modulation of cancer treatment outcomes by the gut microbiota.

Microbiome 2020 03 5;8(1):28. Epub 2020 Mar 5.

Systems Biology & Bioinformatics Unit, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.

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March 2020

KRAS as a druggable target in NSCLC: Rising like a phoenix after decades of development failures.

Cancer Treat Rev 2020 Apr 7;85:101978. Epub 2020 Feb 7.

Oncology Department, University Hospital of Geneva, Switzerland. Electronic address:

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April 2020

Tumor Mutation Burden-From Doubts to Concerns-In Reply.

JAMA Oncol 2019 Oct 24. Epub 2019 Oct 24.

MiRanostics Consulting, Oro Valley, Arizona.

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October 2019

Measuring tumor mutation burden in cell-free DNA: advantages and limits.

Transl Lung Cancer Res 2019 Aug;8(4):553-555

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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August 2019

Tumor Mutation Burden-From Hopes to Doubts.

JAMA Oncol 2019 Jul;5(7):934-935

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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July 2019

Association of Industry and Academic Sponsorship With Negative Phase 3 Oncology Trials and Reported Outcomes on Participant Survival: A Pooled Analysis.

JAMA Netw Open 2019 05 3;2(5):e193684. Epub 2019 May 3.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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May 2019

Atezolizumab plus Chemotherapy in Small-Cell Lung Cancer.

N Engl J Med 2019 02;380(9):888-889

Hôpitaux Universitaires de Genève, Geneva, Switzerland.

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February 2019

Discordant financial conflicts of interest disclosures between clinical trial conference abstract and subsequent publication.

PeerJ 2019 11;7:e6423. Epub 2019 Feb 11.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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February 2019

A new era of treating advanced lung cancer is upon us.

Authors:
Glen J Weiss

Transl Lung Cancer Res 2018 Sep;7(Suppl 3):S202-S205

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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September 2018

Phase Ib/II study of gemcitabine, nab-paclitaxel, and pembrolizumab in metastatic pancreatic adenocarcinoma.

Invest New Drugs 2018 02 8;36(1):96-102. Epub 2017 Nov 8.

Western Regional Medical Center, Cancer Treatment Centers of America, Goodyear, AZ, USA.

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February 2018

Prophylactic cranial irradiation in small-cell lung cancer.

Lancet Oncol 2017 07;18(7):e367

Department of Tumor Biology, National Koranyi Institute of Pulmonology, H-1121, Budapest, Hungary. Electronic address:

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July 2017

A phase Ib study of pembrolizumab plus chemotherapy in patients with advanced cancer (PembroPlus).

Br J Cancer 2017 Jun 6;117(1):33-40. Epub 2017 Jun 6.

Western Regional Medical Center, Cancer Treatment Centers of America, 14200 W Celebrate Life Way, Goodyear, AZ 85338, USA.

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June 2017

Using circulating cell-free DNA to monitor personalized cancer therapy.

Crit Rev Clin Lab Sci 2017 05 10;54(3):205-218. Epub 2017 Apr 10.

a Department of Clinical Pharmacology , University Medical Center Göttingen , Göttingen , Germany.

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May 2017

Reviewing concomitant medications for participants in oncology clinical trials.

Am J Health Syst Pharm 2017 Apr;74(8):580-586

Cancer Treatment Centers of America at Western Regional Medical Center, Goodyear, AZ.

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April 2017

From Bench to Bedside: Attempt to Evaluate Repositioning of Drugs in the Treatment of Metastatic Small Cell Lung Cancer (SCLC).

PLoS One 2016 6;11(1):e0144797. Epub 2016 Jan 6.

Western Regional Medical Center, Cancer Treatment Centers of America, Goodyear, Arizona, United States of America.

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July 2016

Precision medicine: lessons learned from the SHIVA trial.

Authors:
Glen J Weiss

Lancet Oncol 2015 Dec;16(16):e580

Cancer Treatment Centers of America, Goodyear, AZ 85338, USA. Electronic address:

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December 2015

Comparing two assays for clinical genomic profiling: the devil is in the data [Letter of clarification].

Onco Targets Ther 2015 18;8:2643. Epub 2015 Sep 18.

Cancer Treatment Centers of America, Western Regional Medical Center, Goodyear, AZ, USA.

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October 2015

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.

N Engl J Med 2015 Jul;373(5):428-37

From Memorial Sloan Kettering Cancer Center (W.D.T., J.H.H.) and Weill Cornell Medical College (W.D.T.) - both in New York; University of California, Los Angeles, Medical Center, Los Angeles (Z.A.W., B.C., A.S.S.), Plexxikon, Berkeley (P.N.I., C.Z., J.Z., G.H., Y.Z., E.A.B., G.V., L.S., P.S., H.N., M.J.K., A.M., G.T., R.S., C.G., B.L.W., P.H., K.N., H.H.H., P.S.L., S.T.-S., G.B.), and Stanford University School of Medicine, Stanford (M.R.) - all in California; Evergreen Hematology and Oncology, Spokane, WA (S.P.A.); University of Pennsylvania School of Medicine, Philadelphia (A.P.S.); Rocky Mountain Cancer Centers, Denver (A.L.C.); Dana-Farber Cancer Institute (G.I.S., A.J.W.) and Massachusetts General Hospital (E.L.K.) - both in Boston; Vanderbilt University Medical Center, Nashville (V.L.K., I.P.); Virginia G. Piper Cancer Center at Scottsdale Healthcare-Translational Genomics Research Institute (TGen), Scottsdale, AZ (D.D.V.H., G.J.W., R.K.R.); and Spire Sciences, Boca Raton, FL (C.P.).

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July 2015

Influence of Robotic-Assisted Surgery on Readmission Burden.

Authors:
Glen J Weiss

J Clin Oncol 2015 Jul 26;33(19):2229. Epub 2015 May 26.

Cancer Treatment Centers of America, Goodyear, AZ

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July 2015

Translating next-generation sequencing from clinical trials to clinical practice for the treatment of advanced cancers.

Per Med 2015 Mar 20;12(2):155-162. Epub 2015 Jan 20.

Cancer Treatment Centers of America, 14200 Celebrate Life Way, Goodyear, AZ 85338, USA.

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March 2015

Noninvasive image texture analysis differentiates K-ras mutation from pan-wildtype NSCLC and is prognostic.

PLoS One 2014 2;9(7):e100244. Epub 2014 Jul 2.

Imaging Endpoints Core Lab, Scottsdale, Arizona, United States of America; Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Arizona, United States of America.

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February 2015

ALK molecular phenotype in non-small cell lung cancer: CT radiogenomic characterization.

Radiology 2014 Aug 2;272(2):568-76. Epub 2014 Jun 2.

From the Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Box 951721, CHS 17-135, Los Angeles, CA 90095-1721 (S.Y., C.M., M.D.K.); Scottsdale Medical Imaging, Scottsdale, Ariz (R.L.K.); Scottsdale Healthcare, Scottsdale, Ariz (R.L.K.); Departments of Vascular Interventional Radiology (R.O.) and Pathology (A.J.I.), Massachusetts General Hospital, Harvard Medical School, Boston, Mass; Department of Radiology, Mayo Clinic, Phoenix, Ariz (M.B.G.); Department of Radiology, Mayo Clinic, Scottsdale, Ariz (M.B.G.); Cancer Treatment Centers of America, Goodyear, Ariz (G.J.W.); Translational Genomics Research Institute, Phoenix, Ariz (G.J.W.); and Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea (D.W.K.).

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August 2014

Maintaining clarity: Review of maintenance therapy in non-small cell lung cancer.

World J Clin Oncol 2014 May;5(2):103-13

Kristen R Dearing, Glen J Weiss, Department of Clinical Research, Cancer Treatment Centers of America, Goodyear, AZ 85338, United States.

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May 2014

FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion.

Clin Exp Metastasis 2014 Aug 8;31(6):613-23. Epub 2014 Apr 8.

Cancer and Cell Biology Division, The Translational Genomics Research Institute (TGen), 445 N. Fifth St., Suite 400, Phoenix, AZ, 85004, USA,

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August 2014

Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response.

Mol Cancer Res 2014 Apr 27;12(4):550-9. Epub 2014 Jan 27.

Translational Genomics Research Institute, 445 N. Fifth St., Suite 400, Phoenix, AZ 85004.

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April 2014

Molecular characterization may be of PARAMOUNT importance.

J Clin Oncol 2014 Feb 6;32(5):481-2. Epub 2014 Jan 6.

Cancer Treatment Centers of America, Goodyear, AZ.

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February 2014

Heavy Metal Content in Thoracic Tissue Samples from Patients with and without NSCLC.

Lung Cancer Int 2014 9;2014:853158. Epub 2014 Jul 9.

The Translational Genomics Research Institute, 445 N 5th Street, Phoenix, AZ 85004, USA ; Cancer Treatment Centers of America, 14200 W Celebrate Life Way, Goodyear, AZ 85338, USA.

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August 2015

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

PLoS One 2013 30;8(10):e76438. Epub 2013 Oct 30.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare (VGPCC), Scottsdale, Arizona, United States of America ; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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August 2014

Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib.

J Am Acad Dermatol 2014 Jan 1;70(1):60-9. Epub 2013 Nov 1.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Arizona.

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January 2014

Squamous Cell Carcinoma of the Lung with Metastasis to the GI Tract Associated with EGFR Exon 19 Deletion.

Case Rep Med 2013 19;2013:874836. Epub 2013 Sep 19.

Cancer Treatment Centers of America, Goodyear, AZ 85338, USA ; The Translational Genomics Research Institute, Phoenix, AZ 85004, USA ; CRAB Clinical Trials Consortium, Seattle, WA 98101, USA.

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October 2013

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.

Proc Natl Acad Sci U S A 2013 Oct 30;110(42):16868-73. Epub 2013 Sep 30.

Lineberger Comprehensive Cancer Center, Department of Pharmacology, and Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

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October 2013

Long insert whole genome sequencing for copy number variant and translocation detection.

Nucleic Acids Res 2014 Jan 25;42(2):e8. Epub 2013 Sep 25.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA, Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA and Cancer Treatment Centers of America, Medical Oncology, Goodyear, AZ, 85338, USA.

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January 2014

Examining the effect of teleconferences on oncology phase 1 trials.

J Cancer 2013 4;4(6):464-7. Epub 2013 Jul 4.

1. Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, AZ, USA;

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July 2013

Molecular determinants of lung cancer metastasis to the central nervous system.

Transl Lung Cancer Res 2013 Aug;2(4):273-83

Cancer and Cell Biology Division, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA ;

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August 2013

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs.

BMC Genomics 2013 May 4;14:302. Epub 2013 May 4.

Translational Genomics Research Institute, Neurogenomics Division, Phoenix, AZ 85004, USA.

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May 2013

18-FDG PET/CT assessment of basal cell carcinoma with vismodegib.

Cancer Med 2012 Oct 17;1(2):230-6. Epub 2012 Sep 17.

Scottsdale Medical Imaging, Ltd. Scottsdale, AZ; Midwestern University Glendale, AZ, USA.

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October 2012

A phase I study of liposomal-encapsulated docetaxel (LE-DT) in patients with advanced solid tumor malignancies.

Cancer Chemother Pharmacol 2013 Mar 30;71(3):627-33. Epub 2012 Dec 30.

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road, NW, Washington, DC 20007, USA.

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March 2013

Doubling down with inhibitors of Notch and Hedgehog signaling pathways.

Authors:
Glen J Weiss

J Thorac Oncol 2012 Dec;7(16 Suppl 5):S409-10

Virginia G Piper Cancer Center Clinical Trials, Scottsdale Healthcare, Scottsdale, Arizona 85258, USA.

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December 2012

Interpretation of PET scans: do not take SUVs at face value.

J Thorac Oncol 2012 Dec;7(12):1744-1746

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Arizona; Imaging Endpoints Core Lab, Scottsdale, Arizona.

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December 2012

Determinants of patient screen failures in Phase 1 clinical trials.

Invest New Drugs 2013 Jun 8;31(3):774-9. Epub 2012 Nov 8.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, 10510 N 92nd St. Ste 200, Scottsdale, AZ, 85258, USA.

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June 2013

Metastatic basal cell carcinoma in the era of hedgehog signaling pathway inhibitors.

Cancer 2012 Nov 17;118(21):5310-9. Epub 2012 Apr 17.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Arizona; Translational Genomics Research Institute, Phoenix, AZ 85258, USA.

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November 2012

Basal cell adenocarcinoma of the supraglottic larynx: treatment of recurrent disease with tamoxifen.

Rare Tumors 2011 Oct 13;3(4):e55. Epub 2011 Dec 13.

Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale, AZ, USA.

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October 2011

STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma.

PLoS One 2012 2;7(2):e30820. Epub 2012 Feb 2.

Systems Biology, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.

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September 2012

Factors influencing time to determination of the recommended phase 2 dose in phase 1 clinical trials.

Am J Clin Oncol 2013 Apr;36(2):146-50

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Phoenix, AZ 85258, USA.

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April 2013

Progression-free Survival Decreases with Each Subsequent Therapy in Patients Presenting for Phase I Clinical Trials.

J Cancer 2012 28;3:7-13. Epub 2011 Nov 28.

1. Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, AZ, USA.

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October 2012

No miR quirk: dysregulation of microRNAs in pancreatic ductal adenocarcinoma.

Microrna 2012 ;1(1):49-58

The Translational Genomics Research Institute 445 North Fifth Street, Phoenix, Arizona 85004 USA.

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December 2014

Hedgehog signaling pathway molecules and ALDH1A1 expression in early-stage non-small cell lung cancer.

Lung Cancer 2012 May 23;76(2):191-6. Epub 2011 Nov 23.

Cancer and Cell Biology Division, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.

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May 2012

Targeting the Hedgehog and Notch signaling pathways.

Authors:
Glen J Weiss

J Thorac Oncol 2011 Nov;6(11 Suppl 4):S1820-1

Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale, AZ 85258, USA.

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November 2011

Resolution of Cullen's sign in patient with metastatic melanoma responding to hypoxia-activated prodrug TH-302.

Dermatol Reports 2011 Oct 1;3(3):e56. Epub 2011 Dec 1.

Threshold Pharmaceuticals, Redwood City, CA, USA.

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October 2011

miRNAs in lung cancer: large roles for small players.

Future Oncol 2011 Sep;7(9):1045-55

The Translational Genomics Research Institute, Phoenix, AZ, USA.

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September 2011

Biomarkers associated with metastasis of lung cancer to brain predict patient survival.

Int J Data Min Bioinform 2011 ;5(3):287-307

Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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September 2011

The hedgehog knows many tricks.

Curr Drug Targets 2011 Dec;12(14):2091-5

Scottsdale Clinical Research Institute, Scottsdale, AZ 85238, USA.

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December 2011