Publications by authors named "Giuseppe Pugliese"

100Publications

Indications for renal biopsy in patients with diabetes. Joint position statement of the Italian Society of Nephrology and the Italian Diabetes Society.

Nutr Metab Cardiovasc Dis 2020 11 19;30(12):2123-2132. Epub 2020 Sep 19.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Rome, Italy; Endocrine and Metabolic Unit, Sant'Andrea University Hospital, Rome, Italy.

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November 2020

Galectin-3 gene deletion results in defective adipose tissue maturation and impaired insulin sensitivity and glucose homeostasis.

Sci Rep 2020 11 18;10(1):20070. Epub 2020 Nov 18.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.

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November 2020

Renal protection with glucagon-like peptide-1 receptor agonists.

Curr Opin Pharmacol 2020 Oct 5;54:91-101. Epub 2020 Oct 5.

Department of Clinical and Molecular Medicine, "La Sapienza" University, and Endocrine and Metabolic Unit, Sant'Andrea University Hospital, Rome, Italy. Electronic address:

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October 2020

Is diabetes mellitus a risk factor for COronaVIrus Disease 19 (COVID-19)?

Acta Diabetol 2020 Nov 31;57(11):1275-1285. Epub 2020 Aug 31.

Diabetes Service, Endocrinology and Metabolic Diseases Unit, IRCCS "Cà Granda - Ospedale Maggiore Policlinico" Foundation, Milan, Italy.

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November 2020

Diabetes promotes invasive pancreatic cancer by increasing systemic and tumour carbonyl stress in Kras mice.

J Exp Clin Cancer Res 2020 Aug 10;39(1):152. Epub 2020 Aug 10.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa, 1035-1039 -, 00189, Rome, Italy.

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August 2020

The Inflammasome in Chronic Complications of Diabetes and Related Metabolic Disorders.

Cells 2020 07 30;9(8). Epub 2020 Jul 30.

Department of Clinical and Molecular Medicine, "La Sapienza" University, 00189 Rome, Italy.

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July 2020

Muscle fatigability in patients with type 2 diabetes: relation with long-term complications.

Diabetes Metab Res Rev 2020 02 11;36(2):e3231. Epub 2019 Nov 11.

Department of Clinical and Molecular Medicine, La Sapienza University, and Diabetes Unit, Sant'Andrea University Hospital, Rome, Italy.

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February 2020

Invest in METs, Not in Meds.

Am J Med 2019 10 19;132(10):e756. Epub 2019 Jul 19.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Rome, Italy; Endocrine-Metabolic Unit, Sant'Andrea University Hospital, Rome, Italy.

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October 2019

Management of diabetes mellitus in patients undergoing liver transplantation.

Pharmacol Res 2019 03 25;141:556-573. Epub 2019 Jan 25.

Diabetes Service, Endocrinology and Metabolic Diseases Unit, IRCCS "Cà Granda - Ospedale Maggiore Policlinico" Foundation, and Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address:

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March 2019

Central role of the β-cell in driving regression of diabetes after liver transplantation in cirrhotic patients.

J Hepatol 2019 05 21;70(5):954-962. Epub 2019 Jan 21.

Diabetes Service, Endocrinology and Metabolic Diseases Unit, IRCCS "Cà Granda - Ospedale Maggiore Policlinico" Foundation, and Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address:

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May 2019

Beyond the Beyond: A Case of an Extraordinary Response to Multiple Lines of Therapy in a de novo Metastatic HER2-Negative Gastric Cancer Patient.

Gastrointest Tumors 2018 Sep 27;5(1-2):14-20. Epub 2018 Jul 27.

Department of Oncology and Haematology, Università di Modena e Reggio Emilia, Policlinico di Modena, Modena, Italy.

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September 2018

Metabolically healthy versus metabolically unhealthy obesity.

Metabolism 2019 03 17;92:51-60. Epub 2018 Nov 17.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Rome, Italy. Electronic address:

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March 2019

Issue focusing: a new topical collection on diabetic nephropathy.

Acta Diabetol 2018 Nov 12;55(11):1091-1092. Epub 2018 Sep 12.

Department of Medical Sciences, University of Turin, Turin, Italy.

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November 2018

Near-infrared spectroscopy in adult cardiac surgery: between conflicting results and unexpected uses.

J Geriatr Cardiol 2017 Nov;14(11):659-661

Department of Cardiovascular Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.

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November 2017

Deficiency of the Purinergic Receptor 2X Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome.

Oxid Med Cell Longev 2017 15;2017:8962458. Epub 2017 Nov 15.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa 1035, 00189 Rome, Italy.

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July 2018

Hypophosphatasia: clinical manifestation and burden of disease in adult patients.

Clin Cases Miner Bone Metab 2017 May-Aug;14(2):230-234. Epub 2017 Oct 25.

Department of Clinical and Molecular Medicine, "Sapienza" University of Rome, "S. Andrea" Hospital, Diabetes Units, Rome, Italy.

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October 2017

Role of Galectin-3 in Bone Cell Differentiation, Bone Pathophysiology and Vascular Osteogenesis.

Int J Mol Sci 2017 Nov 21;18(11). Epub 2017 Nov 21.

Department of Clinical and Molecular Medicine, La Sapienza University, 00185 Rome, Italy.

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November 2017

Impaired glucose metabolism in subjects with the Williams-Beuren syndrome: A five-year follow-up cohort study.

PLoS One 2017 20;12(10):e0185371. Epub 2017 Oct 20.

Diabetes Service, Unit of Endocrinology and Metabolic Diseases, IRCCS "Cà Granda-Ospedale Maggiore Policlinico" Foundation, and Department of Medical Sciences, University of Milan, Milan, Italy.

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November 2017

Preoperative atorvastatin reduces bleeding and blood products use in patients undergoing on-pump coronary artery bypass grafting.

J Cardiovasc Med (Hagerstown) 2017 Dec;18(12):976-982

aDepartment of Cardiovascular Surgery, Università Campus Bio-Medico di Roma, Rome, ItalybDepartment of Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, UKcDepartment of Cardiac Surgery, Centre Cardiologique du Nord de Saint-Denis, Paris, FrancedDepartment of Public Health and Statistics, Università Campus Bio-Medico di Roma, Rome, Italy.

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December 2017

The impact of type 1 diabetes and diabetic polyneuropathy on muscle strength and fatigability.

Acta Diabetol 2017 Jun 11;54(6):543-550. Epub 2017 Mar 11.

Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro De Bosis, 15, 00135, Rome, Italy.

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June 2017

Dietary interventions to contrast the onset and progression of diabetic nephropathy: A critical survey of new data.

Crit Rev Food Sci Nutr 2018 Jul 13;58(10):1671-1680. Epub 2017 Jun 13.

b DINOGMI, University of Genoa Medical School , Genoa , Italy.

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July 2018

Hepatogenous diabetes: Is it time to separate it from type 2 diabetes?

Liver Int 2017 07 31;37(7):950-962. Epub 2016 Dec 31.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Rome, Italy.

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July 2017

Extracorporeal Shockwave Therapy Improves Functional Outcomes of Adhesive Capsulitis of the Shoulder in Patients With Diabetes.

Diabetes Care 2017 02 29;40(2):e12-e13. Epub 2016 Nov 29.

Department of Medical and Surgical Sciences and Translational Medicine, "Sapienza" University of Rome, Rome, Italy

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February 2017

The evolving role of microsatellite instability in colorectal cancer: A review.

Cancer Treat Rev 2016 Dec 27;51:19-26. Epub 2016 Oct 27.

Division of Oncology, University Hospital of Modena, Via del Pozzo 71, 41124 Modena, Italy. Electronic address:

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December 2016

Muscle fatigability in type 2 diabetes.

Diabetes Metab Res Rev 2017 01 16;33(1). Epub 2016 Jun 16.

Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.

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January 2017

Abnormalities of retinal ganglion cell complex at optical coherence tomography in patients with type 2 diabetes: a sign of diabetic polyneuropathy, not retinopathy.

J Diabetes Complications 2016 Apr 30;30(3):469-76. Epub 2015 Dec 30.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa, 1035-1039 - 00189, Rome, Italy; Diabetes Unit, Sant'Andrea Hospital, Via di Grottarossa, 1035-1039 - 00189, Rome, Italy. Electronic address:

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April 2016

Role of Galectin-3 in Obesity and Impaired Glucose Homeostasis.

Oxid Med Cell Longev 2016 6;2016:9618092. Epub 2015 Dec 6.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa 1035-1039, 00189 Rome, Italy.

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December 2016

A bioluminescent mouse model of proliferation to highlight early stages of pancreatic cancer: A suitable tool for preclinical studies.

Ann Anat 2016 Sep 15;207:2-8. Epub 2015 Dec 15.

Department of Research, Advanced Diagnostics and Technological Innovation, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome 00144, Italy. Electronic address:

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September 2016

Prediction of Declining Renal Function and Albuminuria in Patients With Type 2 Diabetes by Metabolomics.

J Clin Endocrinol Metab 2016 Feb 18;101(2):696-704. Epub 2015 Dec 18.

Department of Clinical and Experimental Medicine (A.S., M.L.M., G.Pe., E.F.), and Department of Mathematics (M.L.M.), University of Pisa, 56126 Pisa, Italy; Department of Clinical and Molecular Medicine (G.Pu.), "La Sapienza" University, 00185 Rome, Italy; Metabolon, Inc (J.E.C.), Durham, North Carolina 27713; and National Research Council Institute of Clinical Physiology (E.F.), 56124 Pisa, Italy.

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February 2016

Contribution of β-cell dysfunction and insulin resistance to cirrhosis-associated diabetes: Role of severity of liver disease.

J Hepatol 2015 Dec 20;63(6):1484-90. Epub 2015 Aug 20.

Endocrinology and Metabolic Diseases Unit, Diabetes Service, IRCCS "Cà Granda - Ospedale Maggiore Policlinico" Foundation, University of Milan, Milan, Italy. Electronic address:

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December 2015

Neuromuscular dysfunction in type 2 diabetes: underlying mechanisms and effect of resistance training.

Diabetes Metab Res Rev 2016 Jan 16;32(1):40-50. Epub 2015 Jun 16.

Department of Movement, Human and Health Sciences, 'Foro Italico' University, Rome, Italy.

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January 2016

The dark and bright side of atherosclerotic calcification.

Atherosclerosis 2015 Feb 12;238(2):220-30. Epub 2014 Dec 12.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa, 1035-1039, 00189 Rome, Italy. Electronic address:

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February 2015

Protection from diabetes-induced atherosclerosis and renal disease by D-carnosine-octylester: effects of early vs late inhibition of advanced glycation end-products in Apoe-null mice.

Diabetologia 2015 Apr 4;58(4):845-53. Epub 2014 Dec 4.

Department of Clinical and Molecular Medicine, 'La Sapienza' University, Via di Grottarossa 1035-1039, 00189, Rome, Italy.

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April 2015

Galectin-3: an emerging all-out player in metabolic disorders and their complications.

Glycobiology 2015 Feb 9;25(2):136-50. Epub 2014 Oct 9.

Department of Clinical and Molecular Medicine, "La Sapienza" University, Via di Grottarossa, 1035-1039, Rome 00189, Italy.

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February 2015

Updating the natural history of diabetic nephropathy.

Acta Diabetol 2014 Dec 9;51(6):905-15. Epub 2014 Oct 9.

Department of Clinical and Molecular Medicine, "La Sapienza" University of Rome, Via di Grottarossa, 1035-1039, 00189, Rome, Italy,

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December 2014

Resistant hypertension in patients with type 2 diabetes: clinical correlates and association with complications.

J Hypertens 2014 Dec;32(12):2401-10; discussion 2410

aDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa bDivision of Endocrinology and Metabolic Diseases, University of Verona, Verona cDiabetes Unit, Fondazione IRCCS 'Cà Granda-Ospedale Maggiore Policlinico', Milan dDiabetes Unit, University of Siena, Siena eEndocrinology and Diabetes Unit, Ospedali Riuniti, Bergamo fDepartment of Clinical and Experimental Medicine, University of Padua, Padua gDepartment of Clinical and Biological Sciences, University of Turin, Orbassano, Turin hDepartment of Medical Sciences, University of Foggia, Foggia iEndocrinology Unit, San Giuseppe Hospital, Milan jDepartment of Medical Sciences, University of Cagliari, Cagliari kDepartment of Clinical and Molecular Medicine, 'La Sapienza' University, Rome, Italy.

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December 2014

Loss of TIMP3 exacerbates atherosclerosis in ApoE null mice.

Atherosclerosis 2014 Aug 4;235(2):438-43. Epub 2014 Jun 4.

Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy; Center for Atherosclerosis, Department of Medicine, Policlinico Tor Vergata, 00133 Rome, Italy. Electronic address:

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August 2014

NAVIGATOR: physical activity for cardiovascular health?

Lancet 2014 Mar 20;383(9922):1022-3. Epub 2013 Dec 20.

Diabetes Unit, Sant'Andrea Hospital, Rome, Italy.

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March 2014

Physical exercise as therapy for type 2 diabetes mellitus.

Diabetes Metab Res Rev 2014 Mar;30 Suppl 1:13-23

Metabolic Fitness Association, Rome, Italy; Department of Clinical and Molecular Medicine, 'La Sapienza' University, Rome, Italy; Diabetes Unit, Sant'Andrea Hospital, Rome, Italy.

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March 2014

The galectin-3/RAGE dyad modulates vascular osteogenesis in atherosclerosis.

Cardiovasc Res 2013 Dec 23;100(3):472-80. Epub 2013 Aug 23.

Department of Clinical and Molecular Medicine, 'La Sapienza' University, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.

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December 2013

Improvement of quality of life with supervised exercise training in subjects with type 2 diabetes mellitus.

Arch Intern Med 2011 Nov;171(21):1951-3

Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, S. Maria Imbaro, Chieti, Italy.

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November 2011

Coronary artery-left atrial fistula: displayed by 64-slice computed tomography.

Tex Heart Inst J 2011 ;38(1):90-1

Department of Cardiac Surgery, University of Rome Sapienza - Polo Pontino, 04100 Latina, Italy.

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July 2011