Publications by authors named "Giuseppe Procopio"

100Publications

Pembrolizumab plus axitinib: another step ahead in advanced renal cell carcinoma.

Lancet Oncol 2020 12 23;21(12):1538-1539. Epub 2020 Oct 23.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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December 2020

Immunotherapeutic Targets and Therapy for Renal Cell Carcinoma.

Immunotargets Ther 2020 13;9:273-288. Epub 2020 Nov 13.

Genitourinary Cancer Unit, Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

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November 2020

An Italian, multicenter, real-world, retrospective study of first-line pazopanib in unselected metastatic renal-cell carcinoma patients: the 'Pamerit' study.

Jpn J Clin Oncol 2020 Nov 20. Epub 2020 Nov 20.

Department of Internal Medicine and Therapeutics, University of Pavia, and Division of Translational Oncology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy.

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November 2020

Patient associations and clinical oncology research: how much does a patient's voice really matter?

Expert Rev Pharmacoecon Outcomes Res 2020 Nov 26:1-8. Epub 2020 Nov 26.

Biostatistics and Clinical Trial Unit, Istituto Scientifico Romagnolo per Lo Studio E La Cura Dei Tumori (IRST) Srl, IRCCS , Meldola, Italy.

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November 2020

The emerging role of PARP inhibitors in prostate cancer.

Expert Rev Anticancer Ther 2020 Aug 6;20(8):715-726. Epub 2020 Aug 6.

Department of Medical Oncology, Campus Bio-Medico University of Rome , Rome, Italy.

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August 2020

Patients with sarcomatoid renal cell carcinoma - re-defining the first-line of treatment: A meta-analysis of randomised clinical trials with immune checkpoint inhibitors.

Eur J Cancer 2020 09 23;136:195-203. Epub 2020 Jul 23.

Medical Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy.

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September 2020

Coronavirus: Older Persons With Cancer in Italy in the COVID-19 Pandemic.

Front Oncol 2020 30;10:648. Epub 2020 Apr 30.

Medical Oncology Unit, Humanitas Gavazzeni, Bergamo, Italy.

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April 2020

Current Understanding of Urachal Adenocarcinoma and Management Strategy.

Curr Oncol Rep 2020 Jan 27;22(1). Epub 2020 Jan 27.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

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January 2020

Collecting ducts carcinoma: An orphan disease. Literature overview and future perspectives.

Cancer Treat Rev 2019 Sep 27;79:101891. Epub 2019 Aug 27.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address:

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September 2019

The Evaluation of Response to Immunotherapy in Metastatic Renal Cell Carcinoma: Open Challenges in the Clinical Practice.

Int J Mol Sci 2019 Aug 30;20(17). Epub 2019 Aug 30.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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August 2019

Should we use combination therapy for all advanced renal cell carcinoma?

Lancet Oncol 2019 10 16;20(10):1331-1332. Epub 2019 Aug 16.

Medical Oncology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori di Milano, Milan 20133, Italy.

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October 2019

Do biomarkers play a predictive role for response to novel immunotherapeutic agents in metastatic renal cell carcinoma?

Expert Opin Biol Ther 2019 11 6;19(11):1107-1110. Epub 2019 Aug 6.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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November 2019

Cabozantinib in Renal Cell Carcinoma With Brain Metastases: Safety and Efficacy in a Real-World Population.

Clin Genitourin Cancer 2019 08 13;17(4):291-298. Epub 2019 May 13.

Medical Oncology Department, Genitourinary Cancer Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. Electronic address:

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August 2019

The role of metastasectomy in advanced renal cell carcinoma.

Expert Rev Anticancer Ther 2019 07 8;19(7):603-611. Epub 2019 Jun 8.

a Medical Oncology Department , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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July 2019

Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy: Treatment Patterns From the PROXIMA Prospective Registry.

J Glob Oncol 2018 09;4:1-12

Hideyuki Akaza, The University of Tokyo, Tokyo, Japan; Giuseppe Procopio, Istituto Nazionale Tumori; Sergio Fava, Ospedale Civile di Legnano, Milan; Gaetano Facchini, Istituto Nazionale Tumori Istituto di Ricerca e Cura a Carattere Scientifico Fondazione Pascale, Naples, Italy; Choosak Pripatnanont, Prince of Songkla University, Songkla, Thailand; Duncan Wheatley, Royal Cornwall Hospital, Truro; Mohammad Butt, Castle Hill Hospital, Hull, United Kingdom; Kwong Chuen Leung, Queen Elizabeth Hospital, Hong Kong, Special Administrative Region, People's Republic of China; Alberto Silva, Instituto de Cancer do Ceará, Fortaleza, Brazil; Liliana Castillo, Hospital Oncológico Miguel Pérez Carreño, Valencia, Venezuela; Vasilios Karavasilis, Papageorgiou Hospital and Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece; Ayse Ӧzatılgan, Sanofi, Cambridge, MA; Simon Hitier, Sanofi, Chilly-Mazarin; Evelyne B. Ecstein-Fraisse, Sanofi, Paris, France; and Mustafa Ӧzgüroḡlu, Istanbul University, Istanbul, Turkey.

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September 2018

Management of Metastatic Collecting Duct Carcinoma: An Encouraging Result in a Patient Treated With Cabozantinib.

Clin Genitourin Cancer 2018 06 27;16(3):e521-e523. Epub 2018 Mar 27.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address:

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June 2018

Exposure to Multiple Lines of Treatment and Survival of Patients With Metastatic Renal Cell Carcinoma: A Real-world Analysis.

Clin Genitourin Cancer 2018 08 5;16(4):e735-e742. Epub 2018 Feb 5.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address:

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August 2018

Combination therapies for patients with metastatic renal cell carcinoma.

Lancet Oncol 2018 03 10;19(3):281-283. Epub 2018 Feb 10.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy.

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March 2018

Multimodal treatment of advanced renal cancer in 2017.

Expert Rev Clin Pharmacol 2017 Dec 6;10(12):1395-1402. Epub 2017 Oct 6.

a Department of Medical Oncology , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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December 2017

Castration-naive metastatic prostate cancer: reshaping old paradigms.

Expert Rev Anticancer Ther 2017 10 11;17(10):879-881. Epub 2017 Sep 11.

a Genitourinary Unit, Medical Oncology 1 Department , Fondazione IRCCS Istituto Nazionale Tumori , Milan , Italy.

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October 2017

Management of metastatic castration-resistant prostate cancer: A focus on radium-223: Opinions and suggestions from an expert multidisciplinary panel.

Crit Rev Oncol Hematol 2017 May 6;113:43-51. Epub 2017 Mar 6.

Department of Oncology and Hemato-oncology, Università degli Studi di Milano, Milan; Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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May 2017

Cabozantinib in advanced renal cell carcinoma: a METEOR impact on clinical practice.

Transl Androl Urol 2016 Dec;5(6):974-976

Department of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy.

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December 2016

Does F-18 FDG-PET still play a role in metastatic renal cell carcinoma?

J Med Imaging Radiat Oncol 2017 Apr 9;61(2):250-251. Epub 2017 Jan 9.

Genitourinary Unit, Medical Oncology Department, National Cancer Institute, Milan, Italy.

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April 2017

Everolimus treatment in advanced solid tumors: a personal view.

Future Sci OA 2015 Nov 1;1(3):FSO3. Epub 2015 Nov 1.

SS Oncologia medica Genitourinaria, Fondazione Istituto Nazionale tumori Milan; SS Oncologia medica Genitourinaria, Fondazione Istituto Nazionale tumori Milan.

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November 2015

Treatment of advanced renal cell carcinoma: recent advances and current role of immunotherapy, surgery, and cryotherapy.

Tumori 2017 Jan 26;103(1):15-21. Epub 2016 Oct 26.

Genitourinary Unit, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.

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January 2017

Nivolumab in the treatment of advanced renal cell carcinoma: clinical trial evidence and experience.

Ther Adv Urol 2016 Oct 7;8(5):319-326. Epub 2016 Jul 7.

Medical Oncology Unit 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan, Italy.

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October 2016

Antisecretive and Antitumor Activity of Abiraterone Acetate in Human Adrenocortical Cancer: A Preclinical Study.

J Clin Endocrinol Metab 2016 12 14;101(12):4594-4602. Epub 2016 Sep 14.

Section of Pharmacology, Department of Molecular and Translational Medicine (C.F., M.F., S.V., S.A.B., D.G., C.M., M.M., S.S.), University of Brescia, 25123 Brescia, Italy; Molecular Pharmacology Unit (P.P., M.T., N.Z.), Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy; Oncology Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health (M.C., A.B.), University of Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy; Surgical Clinic, Department of Clinical and Experimental Sciences (G.A.T.), University of Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy; Internal Medicine 1, Department of Clinical and Biological Sciences (M.T.), University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy; and Medical Oncology I, Genitourinary Unit (G.P.), Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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December 2016

Safety of long-term exposure to abiraterone acetate in patients with castration-resistant prostate cancer and concomitant cardiovascular risk factors.

Ther Adv Med Oncol 2016 Sep 5;8(5):323-30. Epub 2016 Jul 5.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via G. Venezian 1, 20133 Milano, Italy.

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September 2016

Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapy.

Drug Des Devel Ther 2016 5;10:2167-72. Epub 2016 Jul 5.

Department of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, Italy.

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May 2017

Immunotherapy advances in uro-genital malignancies.

Crit Rev Oncol Hematol 2016 Sep 17;105:52-64. Epub 2016 Jun 17.

Department of Medical Oncology, Fondazione IRCSS Istituto Nazionale Tumori, Milan, Italy. Electronic address:

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September 2016

Adjuvant treatment for renal cell carcinoma: in the long run will we get the same answers?

Expert Rev Anticancer Ther 2016 08 7;16(8):803-4. Epub 2016 Jul 7.

a Fondazione IRCCS Istituto Nazionale dei Tumori , Medical Oncology , Milano , Italy.

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August 2016

Improved quality of life is the way to longer life.

Lancet Oncol 2016 07 6;17(7):862-863. Epub 2016 Jun 6.

Medical Oncology 1, Fondazione IRCSS Istituto Nazionale dei Tumori, Milan 20133, Italy.

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July 2016

Predicting Molecular Models: Where Are We Going?

EBioMedicine 2015 Nov 9;2(11):1594-5. Epub 2015 Oct 9.

Medical Oncology I, Genitourinary Unit, Fondazione IRSCC Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan (Italy).

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November 2015

Treatment of elderly patients with metastatic renal cell carcinoma.

Expert Rev Anticancer Ther 2016 20;16(3):323-34. Epub 2016 Jan 20.

c Department of Medical Oncology 1 , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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October 2016

Evolving treatment landscape in metastatic renal cell carcinoma: where are we now?

Expert Rev Anticancer Ther 2016 28;16(2):133-5. Epub 2016 Jan 28.

a Genitourinary Unit, Department of Medical Oncology 1 , Fondazione IRCCS Istituto Nazionale Tumori , Milan , Italy.

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September 2016

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma.

N Engl J Med 2015 Nov 25;373(19):1803-13. Epub 2015 Sep 25.

From Memorial Sloan Kettering Cancer Center, New York (R.J.M.), and Roswell Park Cancer Institute, Buffalo (S.G.) - both in New York; Institut Gustave Roussy, Villejuif (B.E.), and Bordeaux University Hospital, Hôpital Saint André, Bordeaux (A.R.) - both in France; Beth Israel Deaconess Medical Center (D.F.M.) and Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Harvard Medical School (T.K.C.) - all in Boston; Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore (H.J.H.); Stanford Cancer Institute, Stanford, CA (S.S.); University of Washington and Fred Hutchinson Cancer Research Center, Seattle (S.S.T.); Vanderbilt University Medical Center, Nashville (J.A.S.); Fondazione Istituto Nazionale Tumori, Milan (G.P.); Fox Chase Cancer Center, Philadelphia (E.R.P.); Hospital Universitario 12 De Octubre, Madrid (D.C.); Westmead Hospital and Macquarie University, Sydney (H.G.); Aarhus University Hospital, Aarhus, Denmark (F.D.); Helsinki University Central Hospital and University of Helsinki, Helsinki (P.B.); South West Wales Cancer Institute and Swansea University College of Medicine, Swansea (J.W.), and Royal Marsden Hospital, London (J.L.) - both in the United Kingdom; University Hospital Essen of University of Duisburg-Essen, Germany (T.C.G.); Chiba Cancer Center, Chiba (T.U.), and Niigata University, Niigata (Y.T.) - both in Japan; Hospital Sao Jose, Beneficencia Portuguesa de São Paulo, São Paulo (F.A.S.); British Columbia Cancer Agency, Vancouver, BC, Canada (C.K.); Bristol-Myers Squibb, Lawrenceville (J.S.S., I.M.W.) and Hopewell (L.-A.X.) - both in New Jersey; and M.D. Anderson Cancer Center, University of Texas, Houston (P.S.).

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November 2015

Clinical experience with temsirolimus in the treatment of advanced renal cell carcinoma.

Ther Adv Urol 2015 Jun;7(3):152-61

Department of Medical Oncology, Unit 1 Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Venezian 1, 20133, Milan, Italy.

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June 2015