Giuseppe Giaccone

Giuseppe Giaccone

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Giuseppe Giaccone

Publications by authors named "Giuseppe Giaccone"

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TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells.

J Cancer Res Clin Oncol 2019 Jun 23;145(6):1509-1519. Epub 2019 Apr 23.

Department of Lung Cancer, Tianjin Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Huan-Hu-Xi Road, Ti-Yuan-Bei, He Xi District, Tianjin, 300060, China.

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http://dx.doi.org/10.1007/s00432-019-02921-3DOI Listing
June 2019

Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer.

PLoS One 2019 28;14(2):e0212097. Epub 2019 Feb 28.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212097PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394902PMC
February 2019

Acquired SETD2 mutation and impaired CREB1 activation confer cisplatin resistance in metastatic non-small cell lung cancer.

Oncogene 2019 01 9;38(2):180-193. Epub 2018 Aug 9.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.

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http://dx.doi.org/10.1038/s41388-018-0429-3DOI Listing
January 2019

Palliative thoracic radiation therapy for non-small cell lung cancer: 2018 Update of an American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline.

Pract Radiat Oncol 2018 Jul - Aug;8(4):245-250. Epub 2018 Apr 4.

Department of Radiation Oncology, London Health Sciences Centre, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.prro.2018.02.009DOI Listing
December 2018

Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Cancer Genet 2018 Dec 9;228-229:131-142. Epub 2018 Nov 9.

Department of Oncology, Georgetown University, Washington, DC, USA; Otto J. Ruesch Center for the Cure of Gastrointestinal Cancer, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22107762183048
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http://dx.doi.org/10.1016/j.cancergen.2018.11.001DOI Listing
December 2018

What Can We Learn From the French Experience in Systemic Treatment of Thymic Epithelial Tumors?

J Thorac Oncol 2018 11;13(11):1623-1624

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183312
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http://dx.doi.org/10.1016/j.jtho.2018.09.009DOI Listing
November 2018

Dasatinib sensitises KRAS-mutant cancer cells to mitogen-activated protein kinase kinase inhibitor via inhibition of TAZ activity.

Eur J Cancer 2018 08 11;99:37-48. Epub 2018 Jun 11.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.05.013DOI Listing
August 2018

Understanding molecular diagnostic technology in oncology through the lens of lung cancer.

Discov Med 2018 08;26(141):21-29

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.

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August 2018

Precision oncology in non-small-cell lung cancer: opportunities and challenges.

Nat Rev Clin Oncol 2018 06;15(6):348-349

Lombardi Comprehensive Cancer Center, Georgetown University, WA, USA.

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http://dx.doi.org/10.1038/s41571-018-0008-0DOI Listing
June 2018

C-MET inhibitors for advanced non-small cell lung cancer.

Expert Opin Investig Drugs 2018 04 11;27(4):363-375. Epub 2018 Apr 11.

a Lombardi Comprehensive Cancer Center , Georgetown University , Washington , DC , USA.

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http://dx.doi.org/10.1080/13543784.2018.1462336DOI Listing
April 2018

A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies.

Cancer Chemother Pharmacol 2018 03 1;81(3):587-596. Epub 2018 Feb 1.

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1007/s00280-018-3533-8DOI Listing
March 2018

Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 study.

Lancet Oncol 2018 03 26;19(3):347-355. Epub 2018 Jan 26.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.

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http://dx.doi.org/10.1016/S1470-2045(18)30062-7DOI Listing
March 2018

Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?

J Thorac Oncol 2018 02 31;13(2):237-245. Epub 2017 Oct 31.

Georgetown University, Washington, District of Columbia. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2017.10.010DOI Listing
February 2018

High cripto-1 and low miR-205 expression levels as prognostic markers in early stage non-small cell lung cancer.

Lung Cancer 2018 02 15;116:38-45. Epub 2017 Dec 15.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC 20057, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.12.010DOI Listing
February 2018

MEK inhibitors under development for treatment of non-small-cell lung cancer.

Expert Opin Investig Drugs 2018 01 13;27(1):17-30. Epub 2017 Dec 13.

b Department of Oncology, Lombardi Comprehensive Cancer Center , Georgetown University , Washington , DC , USA.

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http://dx.doi.org/10.1080/13543784.2018.1415324DOI Listing
January 2018

Case for Stopping Targeted Therapy When Lung Cancer Progresses on Treatment in Hospice-Eligible Patients.

J Oncol Pract 2017 12 5;13(12):780-783. Epub 2017 Oct 5.

Johns Hopkins, Baltimore, MD; Indiana University, Bloomington, IN; UT Southwestern Medical School, Dallas, TX; Virginia Commonwealth University Massey Cancer Center, Richmond; Inova Schar Cancer Institute, Falls Church; ASCO, Alexandria, VA; Einstein Medical Center, Philadelphia, PA; Juravinski Cancer Centre, Hamilton; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Lombardi Cancer Center, Washington, DC; Lahey Hospital & Medical Center, Burlington, MA; William Beaumont Hospital, Royal Oak; University of Michigan, Ann Arbor, MI; Memorial Sloan Kettering Cancer Center, New York, NY; Circle of Hope for Cancer Research, St Cloud, FL; and Helen F. Graham Cancer Center, Newark, DE.

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http://dx.doi.org/10.1200/JOP.2017.027367DOI Listing
December 2017

Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Cancer Genet 2017 Dec 14;218-219:39-50. Epub 2017 Sep 14.

Department of Oncology, Georgetown University, Washington, DC, USA; Otto J. Ruesch Center for the Cure of Gastrointestinal Cancer, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726797PMC
December 2017

Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.

J Clin Oncol 2017 Oct 14;35(30):3484-3515. Epub 2017 Aug 14.

Nasser Hanna, Indiana University Simon Cancer Center, Indianapolis, IN; David Johnson, University of Texas Southwestern Medical Center, Dallas, TX; Sarah Temin, American Society of Clinical Oncology, Alexandria; Sherman Baker Jr, Virginia Commonwealth University Health System Massey Cancer Center, Richmond; Joan H. Schiller, Inova Schar Cancer Institute, Fairfax, VA; Julie Brahmer and Thomas J. Smith, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Peter M. Ellis, Juravinski Cancer Centre, Hamilton; Natasha B. Leighl, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Giuseppe Giaccone, Georgetown University, Washington, DC; Paul J. Hesketh, Lahey Hospital and Medical Center, Burlington, MA; Ishmael Jaiyesimi, William Beaumont Hospital, Royal Oak; Bryan J. Schneider, University of Michigan Health System, Ann Arbor, MI; Gregory J. Riely, Memorial Sloan-Kettering Cancer Center, New York, NY; Joan Tashbar, Circle of Hope for Cancer Research, Orlando, FL; William A. Biermann, Einstein Medical Center Montgomery, East Norriton, PA; and Gregory Masters, Helen F. Graham Cancer Center and Research Institute, Newark, DE.

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http://dx.doi.org/10.1200/JCO.2017.74.6065DOI Listing
October 2017

Phase 2 study of intermittent pulse dacomitinib in patients with advanced non-small cell lung cancers.

Lung Cancer 2017 10 23;112:195-199. Epub 2017 Aug 23.

Lombardi Comprehensive Cancer Center, Georgetown University, 3970 Reservoir Road Washington DC 20007, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.08.017DOI Listing
October 2017

Ganetespib for small cell lung cancer.

Expert Opin Investig Drugs 2017 Jan 15;26(1):103-108. Epub 2016 Dec 15.

a Division of Hematology-Oncology , Georgetown University , Washington , DC , USA.

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http://dx.doi.org/10.1080/13543784.2017.1268599DOI Listing
January 2017

Lessons learned from BATTLE-2 in the war on cancer: the use of Bayesian method in clinical trial design.

Ann Transl Med 2016 Dec;4(23):466

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.

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http://dx.doi.org/10.21037/atm.2016.11.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220042PMC
December 2016

Metastatic lymphoepithelioma-like carcinoma of the lung treated with nivolumab: a case report and focused review of literature.

Transl Lung Cancer Res 2016 Dec;5(6):720-726

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.

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http://dx.doi.org/10.21037/tlcr.2016.11.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233874PMC
December 2016

Expression of mesothelin in thymic carcinoma and its potential therapeutic significance.

Lung Cancer 2016 11 28;101:104-110. Epub 2016 Sep 28.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.09.015DOI Listing
November 2016

Mutations in Latinos From the United States and Latin America.

J Glob Oncol 2016 Oct 9;2(5):259-267. Epub 2016 Mar 9.

, Knight Cancer Institute, Oregon Health and Science University, Portland, OR; , , , , , , , and , Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; , Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru; , Instituto Nacional de Cancerologia, Mexico City, Mexico; , Hospital Oncologico Luis Razetti, Caracas, Venezuela; , Denver Health Medical Center, University of Colorado, Denver, CO; , Kettering Cancer and Blood Specialists, Kettering, OH; and , Facultad de Medicina de la Universidad del Valle, Cochabamba, Bolivia.

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http://dx.doi.org/10.1200/JGO.2015.002105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493261PMC
October 2016

Lung cancer: First-line immunotherapy in lung cancer - taking the first step.

Nat Rev Clin Oncol 2016 10 13;13(10):595-6. Epub 2016 Sep 13.

Lombardi Comprehensive Cancer Center, Georgetown University, 2970 Reservoir Road NW, Washington District of Columbia 20007, USA.

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http://dx.doi.org/10.1038/nrclinonc.2016.148DOI Listing
October 2016

PI3K as a Potential Therapeutic Target in Thymic Epithelial Tumors.

J Thorac Oncol 2016 08 24;11(8):1345-1356. Epub 2016 Apr 24.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319212PMC
August 2016

EMT is associated with, but does not drive resistance to ALK inhibitors among EML4-ALK non-small cell lung cancer.

Mol Oncol 2016 Apr 24;10(4):601-9. Epub 2015 Nov 24.

Department of Oncology, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, DC, 20007, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423150PMC
April 2016

Novel approaches in cancer immunotherapy.

Discov Med 2016 04;21(116):267-74

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.

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April 2016

Treatment of Small-Cell Lung Cancer: American Society of Clinical Oncology Endorsement of the American College of Chest Physicians Guideline.

J Oncol Pract 2016 Jan;12(1):83-86

Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; Georgetown University, Washington, DC; and American Society of Clinical Oncology, Alexandria, VA.

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http://dx.doi.org/10.1200/JOP.2015.008201DOI Listing
January 2016

Treatment of Small-Cell Lung Cancer: American Society of Clinical Oncology Endorsement of the American College of Chest Physicians Guideline.

J Clin Oncol 2015 Dec 8;33(34):4106-11. Epub 2015 Sep 8.

Charles M. Rudin and M. Catherine Pietanza, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; Nofisat Ismaila, American Society of Clinical Oncology, Alexandria, VA; Christine L. Hann, Johns Hopkins University, Baltimore, MD; Narinder Malhotra, Correct Care Solutions, Pittsburgh; Andrew T. Turrisi III, DeltaMedix, Scranton, PA; Benjamin Movsas, Henry Ford Hospital, Detroit, MI; Kim Norris, Lung Cancer Foundation of America, Los Angeles, CA; Suresh S. Ramalingam, Emory University, Atlanta, GA; and Giuseppe Giaccone, Georgetown University, Washington, DC.

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http://jco.ascopubs.org/content/early/2015/09/03/JCO.2015.63
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.63.7918
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http://dx.doi.org/10.1200/JCO.2015.63.7918DOI Listing
December 2015

Novel Treatments for Thymoma and Thymic Carcinoma.

Front Oncol 2015 30;5:267. Epub 2015 Nov 30.

Lombardi Comprehensive Cancer Center, Georgetown University , Washington, DC , USA.

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http://dx.doi.org/10.3389/fonc.2015.00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663242PMC
December 2015

Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.

J Clin Oncol 2015 Oct 31;33(30):3488-515. Epub 2015 Aug 31.

Gregory A. Masters, Helen F. Graham Cancer Center, Newark, DE; Sarah Temin, American Society of Clinical Oncology, Alexandria; Sherman Baker Jr, Virginia Commonwealth University; David Trent, Virginia Cancer Center, Richmond, VA; Christopher G. Azzoli, Massachusetts General Hospital Cancer Center, Boston, MA; Giuseppe Giaccone, Lombardi Cancer Center, Georgetown University, Washington, DC; Julie R. Brahmer and Thomas J. Smith, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; Peter M. Ellis, Juravinski Cancer Centre, Hamilton, Ontario, Canada; Ajeet Gajra, Upstate Medical University, Syracuse, NY; Nancy Rackear, Uniting Against Lung Cancer, Fort Lauderdale, FL; Joan H. Schiller, University of Texas Southwestern; David H. Johnson, University of Texas Southwestern Medical Center at Dallas, Dallas; and John R. Strawn, patient representative, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2015.62.1342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019421PMC
October 2015

Molecular Pathways: Anticancer Activity by Inhibition of Nucleocytoplasmic Shuttling.

Clin Cancer Res 2015 Oct 31;21(20):4508-13. Epub 2015 Aug 31.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.

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http://clincancerres.aacrjournals.org/content/clincanres/21/
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http://dx.doi.org/10.1158/1078-0432.CCR-15-0408DOI Listing
October 2015

Refining the treatment of NSCLC according to histological and molecular subtypes.

Nat Rev Clin Oncol 2015 Sep 12;12(9):511-26. Epub 2015 May 12.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3970 Reservoir Road North West, Washington, DC 20057, USA.

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http://www.nature.com/articles/nrclinonc.2015.90
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http://dx.doi.org/10.1038/nrclinonc.2015.90DOI Listing
September 2015

Reply to A. Stenzinger et al.

J Clin Oncol 2015 Sep 13;33(25):2824. Epub 2015 Jul 13.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC

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http://dx.doi.org/10.1200/JCO.2015.62.7323DOI Listing
September 2015

Next-Generation Sequencing: Targeting Targeted Therapies.

Clin Cancer Res 2015 Aug 6;21(16):3584-5. Epub 2015 Apr 6.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0407DOI Listing
August 2015

Alterations of immune cell subsets in relapsed, thymoma-associated minimal change disease: A case report.

Oncol Lett 2015 Aug 5;10(2):1155-1158. Epub 2015 Jun 5.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1906, USA.

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http://dx.doi.org/10.3892/ol.2015.3325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509017PMC
August 2015

Definitive and Adjuvant Radiotherapy in Locally Advanced Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline.

J Clin Oncol 2015 Jun 5;33(18):2100-5. Epub 2015 May 5.

Andrea Bezjak, Princess Margaret Cancer Center, Toronto, Ontario, Canada; Sarah Temin, American Society of Clinical Oncology, Alexandria, VA; Gregg Franklin, New Mexico Cancer Center, Albuquerque, NM; Giuseppe Giaccone, Lombardi Cancer Center, Washington, DC; Ramaswamy Govindan, Washington University, St Louis, MO; Melissa L. Johnson, Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Andreas Rimner, Memorial Sloan Kettering Cancer Center; Bryan J. Schneider, Weill Cornell Medical College, New York, NY; John Strawn, Patient Representative, Houston, TX; and Christopher G. Azzoli, Massachusetts General, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2014.59.2360
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http://dx.doi.org/10.1200/JCO.2014.59.2360DOI Listing
June 2015

Trends and Characteristics of Young Non-Small Cell Lung Cancer Patients in the United States.

Front Oncol 2015 26;5:113. Epub 2015 May 26.

Lombardi Cancer Center, Georgetown University , Washington DC , USA.

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http://dx.doi.org/10.3389/fonc.2015.00113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443720PMC
June 2015

Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.

J Clin Oncol 2015 Mar 9;33(9):1000-7. Epub 2015 Feb 9.

Ariel Lopez-Chavez, Anish Thomas, Arun Rajan, Mark Raffeld, Betsy Morrow, Ronan Kelly, Corey Allan Carter, Udayan Guha, Keith Killian, Christopher C. Lau, Zied Abdullaev, Liqiang Xi, Svetlana Pack, Paul S. Meltzer, David J. Liewehr, Seth M. Steinberg, Arlene Berman, Eva Szabo, Yisong Wang, and Giuseppe Giaccone, National Cancer Institute; Austin Doyle, Cancer Therapy Evaluation Program, Bethesda, MD; Ariel Lopez-Chavez, Christopher L. Corless, Alan Sandler, Carol Beadling, and Andrea Warrick, Knight Cancer Institute, Oregon Health and Science University, Portland, OR; Ariel Lopez-Chavez, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL; and Yisong Wang and Giuseppe Giaccone, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.

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http://jco.ascopubs.org/content/early/2015/02/03/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.2007
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http://dx.doi.org/10.1200/JCO.2014.58.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356709PMC
March 2015

Multiorgan autoimmune manifestations associated with thymoma.

J Thorac Oncol 2015 Feb;10(2):e5-7

*GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and †Medical Oncology, Lombardi Cancer Center, Georgetown University, Washington, DC.

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http://dx.doi.org/10.1097/JTO.0000000000000324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306236PMC
February 2015

Mutations of epigenetic regulatory genes are common in thymic carcinomas.

Sci Rep 2014 Dec 8;4:7336. Epub 2014 Dec 8.

1] Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 [2] Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC 20007.

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http://dx.doi.org/10.1038/srep07336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258655PMC
December 2014

Classification of current anticancer immunotherapies.

Oncotarget 2014 Dec;5(24):12472-508

Equipe 11 labellisée pas la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France. INSERM, U1138, Paris, France. Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France. Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France. Pôle de Biologie, Hôpital Européen Georges Pompidou (HEGP), AP-HP, Paris, France.

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https://lirias.kuleuven.be/bitstream/123456789/502976/1/2998
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http://oncotarget.com/abstract/2998
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350348PMC
http://dx.doi.org/10.18632/oncotarget.2998DOI Listing
December 2014

Biomarkers in early-stage non-small-cell lung cancer: current concepts and future directions.

J Thorac Oncol 2014 Nov;9(11):1609-17

*Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, Bethesda, Maryland; and †Department of Medicine, Division of Hematology/Oncology, Lombardi Cancer Center, Georgetown University, Washington, DC.

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http://dx.doi.org/10.1097/JTO.0000000000000302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254270PMC
November 2014

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposal for an evidence-based stage classification system for the forthcoming (8th) edition of the TNM classification of malignant tumors.

J Thorac Oncol 2014 Sep;9(9 Suppl 2):S65-72

*Thoracic Surgery, Yale University, New Haven, CT; †Biostatistics, Cancer Research and Biostatistics, Seattle, WA; ‡Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan; §Radiation Oncology, Queen's University, Ontario, Canada; ‖Thoracic Surgery, University of Torino, Torino, Italy; ¶Medical Oncology, Georgetown University, Washington, DC; #Thoracic Surgery, Sloan Kettering Cancer Center, New York, NY; **Thoracic Surgery, Samsung Medical Center, Seoul, South Korea; ††Thoracic Surgery, University of Tokushima, Tokushima, Japan; ‡‡Thoracic Surgery, University of Pisa, Pisa, Italy; §§Pathology, Regina Elena National Cancer Institute, Rome, Italy; ‖‖Radiology, MD Anderson Cancer Center, Houston, TX; ¶¶Pathology, Royal Brompton Hospital, London, UK; ##Thoracic Surgery, Osaka University, Osaka, Japan; ***Thoracic Surgery, Antwerp University Hospital, Antwerp, Belgium; and ‖‖‖Thoracic Radiology, University of Maryland, Baltimore, Maryland.

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https://ccehub.org/app/site/collections/itmig-docs/JTO2014st
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http://linkinghub.elsevier.com/retrieve/pii/S155608641533327
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http://dx.doi.org/10.1097/JTO.0000000000000290DOI Listing
September 2014

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the T Component for the forthcoming (8th) edition of the TNM classification of malignant tumors.

J Thorac Oncol 2014 Sep;9(9 Suppl 2):S73-80

*Pathology, Royal Brompton Hospital, London, United Kingdom; †Thoracic Surgery, Yale University, New Haven, Connecticut; ‡Pathology, Regina Elena National Cancer Institute, Rome, Italy; §Thoracic Surgery, Samsung Medical Center, Seoul, South Korea; ‖Biostatistics, Cancer Research And Biostatistics, Seattle, Washington; ¶Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan; #Radiation Oncology, Queen's University, Ontario, Canada; **Thoracic Surgery, University of Torino, Torino, Italy; ††Medical Oncology, Georgetown University, Washington, District of Columbia; ‡‡Thoracic Surgery, Sloan Kettering Cancer Center, New York, New York; §§Thoracic Surgery, University of Tokushima, Tokushima, Japan; ‖‖Thoracic Surgery, University of Pisa, Pisa, Italy; ¶¶Radiology, MD Anderson Cancer Center, Houston, Texas; ##Thoracic Surgery, Osaka University, Osaka, Japan; and ***Thoracic Surgery, Antwerp University Hospital, Antwerp, Belgium.

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https://ccehub.org/app/site/collections/itmig-docs/JTO2014st
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http://linkinghub.elsevier.com/retrieve/pii/S155608641533328
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http://dx.doi.org/10.1097/JTO.0000000000000303DOI Listing
September 2014

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors.

J Thorac Oncol 2014 Sep;9(9 Suppl 2):S81-7

*Thoracic Surgery, University of Tokushima, Tokushima, Japan; †Thoracic Surgery, Antwerp University Hospital, Antwerp, Belgium; ‡Thoracic Surgery, Yale University, New Haven, CT; §Thoracic Surgery, Osaka University, Osaka, Japan; ‖Biostatistics, Cancer Research And Biostatistics, Seattle, WA; ¶Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan; #Radiation Oncology, Queen's University, Ontario, Canada; **Thoracic Surgery, University of Torino, Torino, Italy; ††Medical Oncology, Georgetown University, Washington, DC; ‡‡Thoracic Surgery, Sloan Kettering Cancer Center, New York, NY; §§Thoracic Surgery, Samsung Medical Center, Seoul, South Korea; ‖‖Thoracic Surgery, University of Pisa, Pisa, Italy; ¶¶Pathology, Regina Elena National Cancer Institute, Rome, Italy; ##Radiology, MD Anderson Cancer Center, Houston, TX; ***Pathology, Royal Brompton Hospital, London, UK.

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http://dx.doi.org/10.1097/JTO.0000000000000291DOI Listing
September 2014

The ITMIG/IASLC Thymic Epithelial Tumors Staging Project: A Proposed Lymph Node Map for Thymic Epithelial Tumors in the Forthcoming 8th Edition of the TNM Classification of Malignant Tumors.

J Thorac Oncol 2014 Sep;9(9 Suppl 2):S88-96

*Thoracic Surgery, Columbia University, New York, New York; †Thoracic Surgery, Yale University, New Haven, Connecticut; ‡Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan; §Radiation Oncology, Queen's University, Ontario, Canada; ‖Thoracic Surgery, University of Torino, Torino, Italy; ¶Medical Oncology, Georgetown University, Washington, DC; #Thoracic Surgery, Sloan Kettering Cancer Center, NY, New York; **Thoracic Surgery, Samsung Medical Center, Seoul, South Korea; ††Thoracic Surgery, University of Tokushima, Tokushima, Japan; ‡‡Thoracic Surgery, University of Pisa, Pisa, Italy; §§Pathology, Regina Elena National Cancer Institute, Rome, Italy; ‖‖Radiology, MD Anderson Cancer Center, Houston, Texas; ¶¶Pathology, Royal Brompton Hospital, London, UK; ##Thoracic Surgery, Osaka University, Osaka, Japan; ***Thoracic Surgery, Antwerp University Hospital, Antwerp, Belgium.

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September 2014

Oncogenic drivers, targeted therapies, and acquired resistance in non-small-cell lung cancer.

J Mol Med (Berl) 2014 Jul 23;92(7):697-707. Epub 2014 May 23.

Georgetown University, Washington, DC, USA.

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http://dx.doi.org/10.1007/s00109-014-1165-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696571PMC
July 2014

CYB5A and autophagy-mediated cell death in pancreatic cancer.

Autophagy 2014 Apr 17;10(4):697-8. Epub 2014 Jan 17.

Lombardi Comprehensive Cancer Center; Georgetown University; Department of Oncology; Washington, DC USA.

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http://dx.doi.org/10.4161/auto.27803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091157PMC
April 2014

Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer.

J Thorac Oncol 2014 Apr;9(4):567-71

*Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; †Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; and ‡Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1097/JTO.0000000000000089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705182PMC
April 2014

Effect of talactoferrin alfa on the immune system in adults with non-small cell lung cancer.

Oncologist 2013 11;18(7):821-2. Epub 2013 Jul 11.

Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health,Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1634/theoncologist.2013-0199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720636PMC
March 2014

Emerging protein kinase inhibitors for non-small cell lung cancer.

Expert Opin Emerg Drugs 2014 Mar 20;19(1):51-65. Epub 2013 Dec 20.

Georgetown University, Lombardi Comprehensive Cancer Center, Department of Medicine , Washington, DC , USA.

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http://www.tandfonline.com/doi/full/10.1517/14728214.2014.87
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http://dx.doi.org/10.1517/14728214.2014.873403DOI Listing
March 2014

Systemic therapy, clinical outcomes, and overall survival in locally advanced or metastatic pulmonary carcinoid: a brief report.

J Thorac Oncol 2014 Mar;9(3):414-8

Departments of *Medical Oncology, †Surgery, and ‡Pathology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; and §Medical Oncology Branch, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1097/JTO.0000000000000065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322909PMC
March 2014

Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC.

J Thorac Oncol 2014 Feb;9(2):144-53

*SITEP (Service d'Innovations Therapeutiques Precoces), Department of Medicine, Gustave Roussy, †Institut Gustave Roussy, University Paris Sud, Villejuif, France; ‡Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia; §Thoracic Multidisciplinary Committee, Gustave Roussy, University Paris Sud, Villejuif, France; and ‖Department of Medical Oncology, University of Athens School of Medicine, Athens, Greece.

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http://dx.doi.org/10.1097/JTO.0000000000000074DOI Listing
February 2014

Lung cancer in 2013: Refining standard practice and admitting uncertainty.

Nat Rev Clin Oncol 2014 Feb 21;11(2):69-70. Epub 2014 Jan 21.

Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Road NW, Washington, DC 20007, USA.

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http://dx.doi.org/10.1038/nrclinonc.2013.251DOI Listing
February 2014

Role of CYB5A in pancreatic cancer prognosis and autophagy modulation.

J Natl Cancer Inst 2014 Jan 3;106(1):djt346. Epub 2013 Dec 3.

Affiliations of authors: Department of Medical Oncology (EG, AA, GJP) and Department of Neurosurgery (TL, VC, TW), VU University Medical Center, and Centre for Integrative Bioinformatics (AvdV), VU University, Amsterdam, the Netherlands; Department of Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, University of Pisa, Pisa, Italy (NF, UB, EV); Department of Neurology, Stanford University, Stanford, CA (VC); Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Boston, MA (TW); Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (QW, J-HL, YW, GG).

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http://dx.doi.org/10.1093/jnci/djt346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906994PMC
January 2014

The Janus kinases inhibitor AZD1480 attenuates growth of small cell lung cancers in vitro and in vivo.

Clin Cancer Res 2013 Dec 24;19(24):6777-86. Epub 2013 Oct 24.

Authors' Affiliations: Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; and Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872034PMC
December 2013

The IASLC/ITMIG thymic malignancies staging project: development of a stage classification for thymic malignancies.

J Thorac Oncol 2013 Dec;8(12):1467-73

*Department of Thoracic Surgery, Yale New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut; †Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan; ‡Biostatistics, Cancer Research And Biostatistics, Seattle, Washington; §Radiation Oncology, Queen's University, Ontario, Canada; ‖Medical Oncology, National Cancer Institute, Bethesda, Maryland; ¶Thoracic Surgery, Sloan-Kettering Cancer Center, New York, New York; #Thoracic Surgery, Samsung Medical Center, Seoul, South Korea; **Thoracic Surgery, University of Tokushima, Tokushima, Japan; ††Thoracic Surgery, University of Pisa, Pisa, Italy; ‡‡Pathology, Regina Elena National Cancer Institute, Rome, Italy; §§Radiology, MD Anderson Cancer Center, Houston, Texas; ‖‖Pathology, Royal Brompton Hospital, London, United Kingdom; ¶¶Thoracic Surgery, Osaka University, Osaka, Japan; ##Thoracic Surgery, University of Torino, Torino, Italy; ***Thoracic Surgery, Antwerp University Hospital, Antwerp, Belgium; ††† Members of the Staging and Prognostic Factors Committee are listed in the Appendix 1; ‡‡‡ Members of the Advisory Boards are listed in the Appendices 2, 3, and 4; and §§§ Members of the Participating Institutions of the Thymic Domain are listed in the Appendix 5.

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http://dx.doi.org/10.1097/JTO.0000000000000017DOI Listing
December 2013

Whole genome and transcriptome sequencing of a B3 thymoma.

PLoS One 2013 5;8(4):e60572. Epub 2013 Apr 5.

Medical Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618227PMC
October 2013

Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy.

Front Oncol 2013 Oct 9;3:261. Epub 2013 Oct 9.

University of Zagreb, School of Medicine, Department for Respiratory Diseases Jordanovac, University Hospital Center Zagreb , Zagreb , Croatia.

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http://dx.doi.org/10.3389/fonc.2013.00261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793201PMC
October 2013

Thymomas: the need for prospective studies.

J Thorac Oncol 2013 Oct;8(10):1230-1

Department of Medicine, Division of Hematology/Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.

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http://dx.doi.org/10.1097/JTO.0b013e3182a8fd9eDOI Listing
October 2013

Acute autoimmune hepatitis, myositis, and myasthenic crisis in a patient with thymoma.

J Thorac Oncol 2013 Oct;8(10):e87-8

Medical Oncology Branch, National Cancer Institute/National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1097/JTO.0b013e318298832bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901944PMC
October 2013

Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors.

Clin Cancer Res 2013 Apr 26;19(8):1960-71. Epub 2013 Feb 26.

Medical Oncology Branch; Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630263PMC
April 2013

"Pseudocavitation" in thymic carcinoma during treatment with sunitinib.

J Thorac Oncol 2013 Apr;8(4):511-2

Medical Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/JTO.0b013e318284378fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602913PMC
April 2013

Response to: intrapulmonary lymph node retrieval.

Transl Lung Cancer Res 2013 Apr;2(2):E37-8

Medical Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2013.03.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369860PMC
April 2013