Giuseppe Basta

Giuseppe Basta

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Giuseppe Basta

Giuseppe Basta

Publications by authors named "Giuseppe Basta"

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Engineered Alginate Microcapsules for Molecular Therapy Through Biologic Secreting Cells.

Tissue Eng Part C Methods 2019 May;25(5):296-304

1 Laboratory for Endocrine Cell Transplants and Biohybrid Organs, Department of Medicine, Section of Endocrinology and Metabolism, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1089/ten.TEC.2018.0329DOI Listing
May 2019

Remission of hyperglycemia in spontaneously diabetic NOD mice upon transplant of microencapsulated human umbilical cord Wharton jelly-derived mesenchymal stem cells (hUCMS).

Xenotransplantation 2019 03 15;26(2):e12476. Epub 2018 Dec 15.

Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology, and Laboratory for Endocrine Cell Transplants and Biohybrid Organs, Department of Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1111/xen.12476DOI Listing
March 2019

Umbilical cord mesenchymal stem cells for the treatment of autoimmune diseases: beware of cell-to-cell contact.

Ann Rheum Dis 2018 03 13;77(3):e14. Epub 2017 Jun 13.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1136/annrheumdis-2017-211790DOI Listing
March 2018

Surface Hydrophilicity of Poly(l-Lactide) Acid Polymer Film Changes the Human Adult Adipose Stem Cell Architecture.

Polymers (Basel) 2018 Feb 1;10(2). Epub 2018 Feb 1.

Department of Chemistry, Biology and Biotechnologies, Biochemistry and Molecular Biology Unit, University of Perugia, Via del Giochetto, 06126 Perugia, Italy.

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http://dx.doi.org/10.3390/polym10020140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414915PMC
February 2018

Microencapsulation of Islets for the Treatment of Type 1 Diabetes Mellitus (T1D).

Methods Mol Biol 2017 ;1479:283-304

Laboratory for Endocrine Cell Transplants and Biohybrid Organs, Department of Medicine, Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology, University of Perugia, Piazzale Gambuli, 1/8, 1, Perugia, 06123, Italy.

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http://link.springer.com/10.1007/978-1-4939-6364-5_23
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http://dx.doi.org/10.1007/978-1-4939-6364-5_23DOI Listing
December 2017

Human Umbilical Cord Wharton Jelly-Derived Adult Mesenchymal Stem Cells, in Biohybrid Scaffolds, for Experimental Skin Regeneration.

Stem Cells Int 2017 31;2017:1472642. Epub 2017 Dec 31.

Department of Medicine, Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology and Laboratory for Endocrine Cell Transplants and Biohybrid Organs, University of Perugia, Piazza Lucio Severi, Perugia, Italy.

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http://dx.doi.org/10.1155/2017/1472642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804405PMC
December 2017

Design of a nanocomposite substrate inducing adult stem cell assembly and progression toward an Epiblast-like or Primitive Endoderm-like phenotype via mechanotransduction.

Biomaterials 2017 Nov 16;144:211-229. Epub 2017 Aug 16.

Department of Chemistry, Biology and Biotechnology, Biochemistry and Molecular Biology Unit, University of Perugia, Italy; CEMIN-Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.08.015DOI Listing
November 2017

Alginates in Pharmaceutics and Biomedicine: Is the Future so Bright?

Curr Pharm Des 2015 ;21(33):4917-35

Department of Pharmaceutical Sciences, University of Perugia, via del Liceo, 1- 06123 Perugia, Italy.

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http://dx.doi.org/10.2174/1381612821666150820105639DOI Listing
August 2016

Functional Profiles of Human Umbilical Cord-Derived Adult Mesenchymal Stem Cells in Obese/Diabetic Versus Healthy Women.

Curr Diabetes Rev 2016 Jun 28. Epub 2016 Jun 28.

Department of Medicine, University of Perugia, Piazzale Gambuli, 1/8, 1 06123 Perugia, Italy.

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June 2016

Insights in Behavior of Variably Formulated Alginate-Based Microcapsules for Cell Transplantation.

Biomed Res Int 2015 20;2015:965804. Epub 2015 May 20.

Interdisciplinary Laboratory for Endocrine Cell Transplants and Biohybrid Organs, Department of Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via Enrico dal Pozzo, s.n.c., 06126 Perugia, Italy.

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http://dx.doi.org/10.1155/2015/965804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452837PMC
March 2016

Restoration of t cell substes of patients with type 1 diabetes mellitus by microencapsulated human umbilical cord Wharton jelly-derived mesenchymal stem cells: An in vitro study.

Clin Immunol 2016 Feb 8;163:34-41. Epub 2015 Dec 8.

Department of Medicine, Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology, Laboratory for Endocrine Cell Transplants and Biohybrid Organs, University of Perugia, Piazzale Gambuli, Perugia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.12.002DOI Listing
February 2016

Stem cells for the cell and molecular therapy of type 1 diabetes mellitus (T1D): the gap between dream and reality.

Am J Stem Cells 2015 15;4(1):22-31. Epub 2015 Mar 15.

Department of Medicine, Section of Clinical Cardiovascular, Endocrine and Metabolic Physiology, University of Perugia School of Medicine at Terni Terni, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396156PMC
May 2015

In vitro immunomodulatory effects of microencapsulated umbilical cord Wharton jelly-derived mesenchymal stem cells in primary Sjögren's syndrome.

Rheumatology (Oxford) 2015 Jan 26;54(1):163-8. Epub 2014 Jul 26.

Rheumatology Unit, Department of Medicine, Laboratory for the Study and Transplant of Pancreatic Islets (LSTPI) and Department of Internal Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1093/rheumatology/keu292DOI Listing
January 2015

Clinical application of microencapsulated islets: actual prospectives on progress and challenges.

Adv Drug Deliv Rev 2014 Apr 1;67-68:84-92. Epub 2013 Nov 1.

Department of Internal Medicine, University of Perugia, Via Enrico dal Pozzo, s.n.c., Perugia 06126, Italy.

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http://dx.doi.org/10.1016/j.addr.2013.09.020DOI Listing
April 2014

Stem cells for pancreatic β-cell replacement in diabetes mellitus: actual perspectives.

Curr Opin Organ Transplant 2014 Apr;19(2):162-8

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1097/MOT.0000000000000055DOI Listing
April 2014

Treatment of diabetes mellitus with microencapsulated fetal human liver (FH-B-TPN) engineered cells.

Biomaterials 2013 May 28;34(16):4002-4012. Epub 2013 Feb 28.

Laboratory for the Study and Transplant of Pancreatic Islets (LSTPI), Department of Internal Medicine, University of Perugia, Via Enrico dal Pozzo, s.n.c., Perugia 06126, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2013.02.026DOI Listing
May 2013

Conformal polymer coatings for pancreatic islets transplantation.

Int J Pharm 2013 Jan 16;440(2):141-7. Epub 2012 Oct 16.

Department of Chemistry and Technology of Drugs, via del Liceo 1, 06123 Perugia, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S03785173120095
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http://dx.doi.org/10.1016/j.ijpharm.2012.10.010DOI Listing
January 2013

The functional performance of microencapsulated human pancreatic islet-derived precursor cells.

Biomaterials 2011 Dec 1;32(35):9254-62. Epub 2011 Sep 1.

Laboratory for the Study and Transplant of Pancreatic Islets, Department of Internal Medicine, University of Perugia, Perugia, Via Enrico dal Pozzo, s.n.c., 06126, Italy.

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http://dx.doi.org/10.1016/j.biomaterials.2011.08.052DOI Listing
December 2011

New simple and rapid method for purification of mesenchymal stem cells from the human umbilical cord Wharton jelly.

Tissue Eng Part A 2011 Nov 6;17(21-22):2651-61. Epub 2011 Sep 6.

Section of Internal Medicine and Endocrine and Metabolic Sciences (Di.M.I.), Department of Internal Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1089/ten.TEA.2010.0587DOI Listing
November 2011

Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases.

Diabetes Care 2011 Nov 16;34(11):2406-9. Epub 2011 Sep 16.

Department of Internal Medicine, Laboratory for the Study and Transplant of Pancreatic Islets, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.2337/dc11-0731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198271PMC
November 2011

Immunoisolation of pancreatic islet grafts with no recipient's immunosuppression: actual and future perspectives.

Curr Diab Rep 2011 Oct;11(5):384-91

Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, via Enrico dal Pozzo, snc, Perugia, Italy.

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http://dx.doi.org/10.1007/s11892-011-0219-6DOI Listing
October 2011

Bioactive long-term release from biodegradable microspheres preserves implanted ALG-PLO-ALG microcapsules from in vivo response to purified alginate.

Pharm Res 2010 Feb 31;27(2):285-95. Epub 2009 Dec 31.

Dipartimento di Chimica e Tecnologia del Farmaco, Faculty of Pharmacy, University of Perugia, Via del Liceo 1, Perugia, 06123, Italy.

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http://link.springer.com/10.1007/s11095-009-0017-x
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http://dx.doi.org/10.1007/s11095-009-0017-xDOI Listing
February 2010

In vitro-cultured human islet cell monolayers: stemness markers and insulin recovery upon streptozotocin exposure.

Tissue Eng Part A 2009 Dec;15(12):3931-42

Section of Internal Medicine and Endocrine and Metabolic Sciences (Di.M.I.), Department of Internal Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1089/ten.TEA.2009.0124DOI Listing
December 2009

Effect of all trans retinoic acid on lysosomal alpha-D-mannosidase activity in HL-60 cell: correlation with HL-60 cells differentiation.

Mol Cell Biochem 2008 Jan 26;308(1-2):17-24. Epub 2007 Sep 26.

Department of Internal Medicine (Di.M.I.), Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via E. Dal Pozzo, Perugia 06126, Italy.

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http://dx.doi.org/10.1007/s11010-007-9606-3DOI Listing
January 2008

Artificial pancreas to treat type 1 diabetes mellitus.

Methods Mol Med 2007 ;140:197-236

Department of Internal Medicine, University of Perugia, Italy.

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January 2008

Neonatal pig liver-derived progenitors for insulin-producing cells: an in vitro study.

Tissue Eng 2007 Dec;13(12):2923-31

Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1089/ten.2007.0098DOI Listing
December 2007

[New frontiers for the therapy of insulin-dependent diabetes mellitus].

Recenti Prog Med 2006 Dec;97(12):751-8

Dipartimento di Medicina Interna, Sezione di Medicina Interna e Scienze Endocrine e Metaboliche, Università, Perugia.

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December 2006

Preparation and in vitro and in vivo characterization of composite microcapsules for cell encapsulation.

Int J Pharm 2006 Oct 1;324(1):27-36. Epub 2006 Aug 1.

Department of Chemistry and Technology of Drugs, School of Pharmacy, University of Perugia, Via del Liceo 1, 06123 Perugia, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S037851730600604
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http://dx.doi.org/10.1016/j.ijpharm.2006.07.049DOI Listing
October 2006

Accelerated functional maturation of isolated neonatal porcine cell clusters: in vitro and in vivo results in NOD mice.

Cell Transplant 2005 ;14(5):249-61

Department of Internal Medicine (Di.M.I.), Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via E. Dal Pozzo, Perugia 06126, Italy.

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http://dx.doi.org/10.3727/000000005783983034DOI Listing
October 2005

Ketoprofen controlled release from composite microcapsules for cell encapsulation: effect on post-transplant acute inflammation.

J Control Release 2005 Oct;107(3):395-407

Department of Chemistry and Technology of Drugs, School of Pharmacy, University of Perugia, Via del Liceo 1, 06123 Perugia, Italy.

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http://dx.doi.org/10.1016/j.jconrel.2005.06.023DOI Listing
October 2005

Grafts of microencapsulated pancreatic islet cells for the therapy of diabetes mellitus in non-immunosuppressed animals.

Biotechnol Appl Biochem 2004 Apr;39(Pt 2):159-64

Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences (Di.M.I.), University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1042/BA20030151DOI Listing
April 2004

Multifunctional microcapsules for pancreatic islet cell entrapment: design, preparation and in vitro characterization.

Biomaterials 2003 Aug;24(18):3101-14

Department of Medicinal Chemistry and Pharmaceutics, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/s0142-9612(03)00118-2DOI Listing
August 2003