Giuseppe A Palumbo

Center for Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.

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June 2020

Life after ruxolitinib: Reasons for discontinuation, impact of disease phase, and outcomes in 218 patients with myelofibrosis.

Cancer 2020 03 20;126(6):1243-1252. Epub 2019 Dec 20.

Institute of Hematology "L. and A. Seràgnoli", St Orsola-Malpighi University Hospital, Bologna, Italy.

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March 2020

The Role of New Technologies in Myeloproliferative Neoplasms.

Authors:

Giuseppe A Palumbo Stefania Stella Maria Stella Pennisi Cristina Pirosa Elisa Fermo Sonia Fabris Daniele Cattaneo Alessandra Iurlo

Front Oncol 2019 26;9:321. Epub 2019 Apr 26.

Hematology Division, Myeloproliferative Syndromes Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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April 2019

Impact of 2016 WHO diagnosis of early and overt primary myelofibrosis on presentation and outcome of 232 patients treated with ruxolitinib.

Hematol Oncol 2019 Oct 7;37(4):418-423. Epub 2019 Jun 7.

Division of Cellular Biotechnologies and Hematology, University Sapienza, Rome, Italy.

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October 2019

Immune off-target effects of Brentuximab Vedotin in relapsed/refractory Hodgkin Lymphoma.

Authors:

Alessandra Romano Nunziatina L Parrinello Annalisa Chiarenza Giovanna Motta Daniele Tibullo Cesarina Giallongo Piera La Cava Giuseppina Camiolo Fabrizio Puglisi Giuseppe A Palumbo Francesco Di Raimondo

Br J Haematol 2019 05 15;185(3):468-479. Epub 2019 Feb 15.

Section of Haematology, Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.

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May 2019

α-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload.

Authors:

Giuseppina Camiolo Daniele Tibullo Cesarina Giallongo Alessandra Romano Nunziatina L Parrinello Giuseppe Musumeci Michelino Di Rosa Nunzio Vicario Maria V Brundo Francesco Amenta Margherita Ferrante Chiara Copat Roberto Avola Giovanni Li Volti Antonio Salvaggio Francesco Di Raimondo Giuseppe A Palumbo

Int J Mol Sci 2019 Jan 31;20(3). Epub 2019 Jan 31.

Department of Medical, Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.

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January 2019

Differences in presenting features, outcome and prognostic models in patients with primary myelofibrosis and post-polycythemia vera and/or post-essential thrombocythemia myelofibrosis treated with ruxolitinib. New perspective of the MYSEC-PM in a large multicenter study.

Semin Hematol 2018 10 5;55(4):248-255. Epub 2018 Jun 5.

Institute of Hematology "L. and A. Seràgnoli", Sant'Orsola-Malpighi University Hospital, Bologna, Italy.

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October 2018

Impact of comorbidities and body mass index in patients with myelofibrosis treated with ruxolitinib.

Ann Hematol 2019 Apr 4;98(4):889-896. Epub 2018 Dec 4.

Institute of Hematology "L. and A. Seràgnoli", Sant'Orsola-Malpighi University Hospital, Bologna, Italy.

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April 2019

Infection control in patients with myelodysplastic syndromes who are candidates for active treatment: Expert panel consensus-based recommendations.

Authors:

Corrado Girmenia Anna Candoni Mario Delia Roberto Latagliata Alfredo Molteni Esther N Oliva Giuseppe A Palumbo Antonella Poloni Prassede Salutari Valeria Santini Maria Teresa Voso Pellegrino Musto

Blood Rev 2019 03 28;34:16-25. Epub 2018 Oct 28.

Scientific Direction, IRCCS-CROB, Referral Cancer Center of Basilicata, Rionero in Vulture, PZ, Italy.

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March 2019

Durability of spleen response affects the outcome of ruxolitinib-treated patients with myelofibrosis: Results from a multicentre study on 284 patients.

Leuk Res 2018 11 5;74:86-88. Epub 2018 Oct 5.

Division of Hematology, Città della Salute e della Scienza Hospital, Torino, Italy.

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November 2018

Ruxolitinib in elderly patients with myelofibrosis: impact of age and genotype. A multicentre study on 291 elderly patients.

Br J Haematol 2018 10 16;183(1):35-46. Epub 2018 Jul 16.

Division of Cellular Biotechnologies and Haematology, University Sapienza, Roma, Italy.

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October 2018

The use of erythropoiesis-stimulating agents is safe and effective in the management of anaemia in myelofibrosis patients treated with ruxolitinib.

Authors:

Elena Crisà Daniela Cilloni Elena M Elli Vincenzo Martinelli Giuseppe A Palumbo Novella Pugliese Eloise Beggiato Chiara Frairia Marco Cerrano Giuseppe Lanzarone Monia Marchetti Mauro Mezzabotta Mario Boccadoro Dario Ferrero

Br J Haematol 2018 09 9;182(5):701-704. Epub 2018 Jul 9.

Haematology Division, A.O.U. Città della Salute e della Scienza di Torino, University of Turin, Torino, Italy.

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September 2018

Epidemiology, outcome, and risk factors for infectious complications in myelofibrosis patients receiving ruxolitinib: A multicenter study on 446 patients.

Hematol Oncol 2018 Apr 6. Epub 2018 Apr 6.

Institute of Hematology "L. and A. Seràgnoli", Sant'Orsola-Malpighi University Hospital, Bologna, Italy.

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April 2018

Life for patients with myelofibrosis: the physical, emotional and financial impact, collected using narrative medicine-Results from the Italian 'Back to Life' project.

Qual Life Res 2018 06 8;27(6):1545-1554. Epub 2018 Mar 8.

ISTUD Foundation, Milan, Italy.

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June 2018

Identification and assessment of frailty in older patients with chronic myeloid leukemia and myelofibrosis, and indications for tyrosine kinase inhibitor treatment.

Authors:

Massimo Breccia Francesca Palandri Luigiana Luciano Giulia Benevolo Massimiliano Bonifacio Giovanni Caocci Fausto Castagnetti Giuseppe A Palumbo Alessandra Iurlo Francesco Landi

Ann Hematol 2018 May 22;97(5):745-754. Epub 2018 Feb 22.

Department of Geriatrics, Neurosciences and Orthopedics, Catholic University of the Sacred Heart, Rome, Italy.

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May 2018

Patient-reported outcomes enhance the survival prediction of traditional disease risk classifications: An international study in patients with myelodysplastic syndromes.

Cancer 2018 03 12;124(6):1251-1259. Epub 2017 Dec 12.

Data Center and Health Outcomes Research Unit, Italian Group for Adult Hematologic Diseases (GIMEMA), Rome, Italy.

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March 2018

Monocytic myeloid-derived suppressor cells as prognostic factor in chronic myeloid leukaemia patients treated with dasatinib.

Authors:

Cesarina Giallongo Nunziatina L Parrinello Piera La Cava Giuseppina Camiolo Alessandra Romano Marina Scalia Fabio Stagno Giuseppe A Palumbo Roberto Avola Giovanni Li Volti Daniele Tibullo Francesco Di Raimondo

J Cell Mol Med 2018 02 8;22(2):1070-1080. Epub 2017 Dec 8.

Division of Hematology, A.O.U. Policlinico-OVE, University of Catania, Catania, Italy.

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February 2018

Increased SHISA3 expression characterizes chronic lymphocytic leukemia patients sensitive to lenalidomide.

Authors:

Rossana Maffei Stefania Fiorcari Silvia Martinelli Stefania Benatti Jenny Bulgarelli Lara Rizzotto Giulia Debbia Rita Santachiara Gian Matteo Rigolin Francesco Forconi Davide Rossi Luca Laurenti Giuseppe A Palumbo Daniele Vallisa Antonio Cuneo Gianluca Gaidano Mario Luppi Roberto Marasca

Leuk Lymphoma 2018 02 22;59(2):423-433. Epub 2017 Jun 22.

a Division of Hematology, Department of Medical and Surgical Sciences , University of Modena and Reggio Emilia , Modena , Italy.

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February 2018

Proteomic Analysis Reveals Autophagy as Pro-Survival Pathway Elicited by Long-Term Exposure with 5-Azacitidine in High-Risk Myelodysplasia.

Authors:

Alessandra Romano Cesarina Giallongo Piera La Cava Nunziatina L Parrinello Antonella Chiechi Calogero Vetro Daniele Tibullo Francesco Di Raimondo Lance A Liotta Virginia Espina Giuseppe A Palumbo

Front Pharmacol 2017 26;8:204. Epub 2017 Apr 26.

Divisione di Ematologia, Azienda Ospedaliera Policlinico UniversitariaCatania, Italy.

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April 2017

Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single-blind, randomised, controlled, phase 2 superiority trial.

Lancet Haematol 2017 Mar 3;4(3):e127-e136. Epub 2017 Feb 3.

Policlinico Umberto I, Rome, Italy.

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March 2017

Granulocyte-like myeloid derived suppressor cells (G-MDSC) are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells (MSC).

Authors:

Cesarina Giallongo Daniele Tibullo Nunziatina L Parrinello Piera La Cava Michelino Di Rosa Vincenzo Bramanti Cosimo Di Raimondo Concetta Conticello Annalisa Chiarenza Giuseppe A Palumbo Roberto Avola Alessandra Romano Francesco Di Raimondo

Oncotarget 2016 Dec;7(52):85764-85775

Division of Hematology, A.O.U. Policlinico-OVE, Catania, University of Catania, Italy.

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December 2016

Prognostic value of self-reported fatigue on overall survival in patients with myelodysplastic syndromes: a multicentre, prospective, observational, cohort study.

Lancet Oncol 2015 Nov 21;16(15):1506-1514. Epub 2015 Sep 21.

Italian Group for Adult Hematologic Diseases (GIMEMA), Data Center and Health Outcomes Research Unit, Rome, Italy.

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November 2015

Early lenalidomide treatment for low and intermediate-1 International Prognostic Scoring System risk myelodysplastic syndromes with del(5q) before transfusion dependence.

Authors:

Esther N Oliva Michael Lauseker Maria Antonietta Aloe Spiriti Antonella Poloni Agostino Cortelezzi Giuseppe A Palumbo Enrico Balleari Grazia Sanpaolo Antonio Volpe Alessandra Ricco Francesca Ronco Caterina Alati Maria Grazia D'Errigo Irene Santacaterina Andrea Kündgen Ulrich Germing Roberto Latagliata

Cancer Med 2015 Dec 17;4(12):1789-97. Epub 2015 Sep 17.

Department of Cellular Biotechnology and Hematology, La Sapienza University, Rome, Italy.

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December 2015

The genotype of MLH1 identifies a subgroup of follicular lymphoma patients who do not benefit from doxorubicin: FIL-FOLL study.

Haematologica 2015 Apr 16;100(4):517-24. Epub 2015 Jan 16.

Division of Hematology, AOU "Policlinico V. Emanuele", Catania

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April 2015

Prevalence, severity and correlates of fatigue in newly diagnosed patients with myelodysplastic syndromes.

Br J Haematol 2015 Feb 1;168(3):361-70. Epub 2014 Oct 1.

Data Centre and Health Outcomes Research Unit, Italian Group for Adult Haematological Diseases (GIMEMA), Rome, Italy.

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February 2015

Myeloid derived suppressor cells (MDSCs) are increased and exert immunosuppressive activity together with polymorphonuclear leukocytes (PMNs) in chronic myeloid leukemia patients.

Authors:

Cesarina Giallongo Nunziatina Parrinello Daniele Tibullo Piera La Cava Alessandra Romano Annalisa Chiarenza Ignazio Barbagallo Giuseppe A Palumbo Fabio Stagno Paolo Vigneri Francesco Di Raimondo

PLoS One 2014 11;9(7):e101848. Epub 2014 Jul 11.

Department of Clinical and Molecular Biomedicine, section of Hematology, Ferrarotto Hospital, University of Catania, Catania, Italy.

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March 2015

Validation of the revised international prognostic scoring system (IPSS-R) in patients with myelodysplastic syndrome: a multicenter study.

Leuk Res 2014 Jan 26;38(1):57-64. Epub 2013 Oct 26.

Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Düsseldorf, Germany.

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January 2014

Endothelium-mediated survival of leukemic cells and angiogenesis-related factors are affected by lenalidomide treatment in chronic lymphocytic leukemia.

Authors:

Rossana Maffei Stefania Fiorcari Jenny Bulgarelli Lara Rizzotto Silvia Martinelli Gian Matteo Rigolin Giulia Debbia Ilaria Castelli Goretta Bonacorsi Rita Santachiara Francesco Forconi Davide Rossi Luca Laurenti Giuseppe A Palumbo Daniele Vallisa Antonio Cuneo Gianluca Gaidano Mario Luppi Roberto Marasca

Exp Hematol 2014 Feb 6;42(2):126-36.e1. Epub 2013 Nov 6.

Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.

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February 2014

SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation.

Authors:

Cesarina Giallongo Piera La Cava Daniele Tibullo Ignazio Barbagallo Nunziatina Parrinello Alessandra Cupri Fabio Stagno Carla Consoli Annalisa Chiarenza Giuseppe A Palumbo Francesco Di Raimondo

BMC Cancer 2013 Feb 5;13:60. Epub 2013 Feb 5.

Department of Clinical and Molecular Biomedicine, University of Catania, Ospedale Ferrarotto, Italy.

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February 2013

Nuclear translocation of heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells.

Authors:

Daniele Tibullo Ignazio Barbagallo Cesarina Giallongo Piera La Cava Nunziatina Parrinello Luca Vanella Fabio Stagno Giuseppe A Palumbo Giovanni Li Volti Francesco Di Raimondo

Curr Pharm Des 2013 ;19(15):2765-70

Department of Clinical and Molecular Biomedicine Section of Hematology, Ferrarotto Hospital, University of Catania, Catania, Italy.

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September 2013

Arsenic trioxide and ascorbic acid interfere with the BCL2 family genes in patients with myelodysplastic syndromes: an ex-vivo study.

Authors:

Sara Galimberti Francesca Guerrini Flavia Salvi Iacopo Petrini Daniela Gioia Emanuela Messa Giuseppe A Palumbo Daniela Cilloni Mario Petrini Alessandro Levis

J Hematol Oncol 2012 Sep 10;5:53. Epub 2012 Sep 10.

Department of Oncology, Transplant, New Advances in Medicine, Section of Hematology, University of Pisa, Pisa, Italy.

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September 2012

Effects of second-generation tyrosine kinase inhibitors towards osteogenic differentiation of human mesenchymal cells of healthy donors.

Authors:

Daniele Tibullo Ignazio Barbagallo Cesarina Giallongo Piera La Cava Antonio Branca Concetta Conticello Fabio Stagno Annalisa Chiarenza Giuseppe A Palumbo Francesco Di Raimondo

Hematol Oncol 2012 Mar 5;30(1):27-33. Epub 2011 May 5.

Department of Clinical and Molecular Biomedicine, Division of Hematology, Ospedale Ferrarotto, University of Catania, Catania, Italy.

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March 2012

Imatinib increases cytotoxicity of melphalan and their combination allows an efficient killing of chronic myeloid leukemia cells.

Authors:

Cesarina Giallongo Piera La Cava Daniele Tibullo Nunziatina Parrinello Ignazio Barbagallo Vittorio Del Fabro Fabio Stagno Concetta Conticello Alessandra Romano Annalisa Chiarenza Giuseppe A Palumbo Francesco Di Raimondo

Eur J Haematol 2011 Mar 8;86(3):216-25. Epub 2011 Feb 8.

Division of Hematology, Department of Biomedical Sciences, Ospedale Ferrarotto, University of Catania, Catania, Italy.

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March 2011

Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation.

Authors:

Ignazio Barbagallo Angelo Vanella Stephen J Peterson Dong Hyun Kim Daniele Tibullo Cesarina Giallongo Luca Vanella Nunziatina Parrinello Giuseppe A Palumbo Francesco Di Raimondo Nader G Abraham David Asprinio

J Bone Miner Metab 2010 May 19;28(3):276-88. Epub 2009 Nov 19.

Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy.

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May 2010

The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma.

BMC Med Genomics 2009 Apr 30;2:20. Epub 2009 Apr 30.

Dipartimento di Scienze BioMediche, Sezione di Biologia Generale, Biologia Cellulare, Genetica Molecolare G Sichel, Unità di Biologia Genomica e dei Sistemi Complessi, Genetica, Bioinformatica, Università di Catania, 95123 Catania, Italy.

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April 2009