Giuliano Rizzardini

Giuliano Rizzardini

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Giuliano Rizzardini

Giuliano Rizzardini

Publications by authors named "Giuliano Rizzardini"

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COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome?

Clin Exp Rheumatol 2020 Mar-Apr;38(2):337-342. Epub 2020 Mar 22.

Department of Biomedical and Clinical Sciences 'Luigi Sacco', University of Milan, and III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Milan, Italy.

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April 2020

Long-Acting Cabotegravir and Rilpivirine for Maintenance of HIV-1 Suppression.

N Engl J Med 2020 03 4;382(12):1112-1123. Epub 2020 Mar 4.

From the University of Nebraska Medical Center, Omaha (S.S.); Centro Universitario de Ciencias de la Salud, University of Guadalajara, Guadalajara, Mexico (J.-F.A.-V.); Broward Health Medical Center, Broward Health Imperial Point, Fort Lauderdale, FL (G.J.R.); Fatebenefratelli Sacco Hospital, Milan (G.R.); the Center for Infectious Diseases, Berlin (A.B.); Hospital de Elche, Elche, Spain (M.M.); Maxwell Centre, Durban, South Africa (G.L.); the Central Research Institute of Epidemiology, Moscow (V.P.); Metropolis Medical Group, San Francisco (F.B.); Maple Leaf Research, Toronto (G.S.), and GlaxoSmithKline, Mississauga (J.H.) - both in Ontario, Canada; Fundación Huésped, Buenos Aires (P.C.); Chungnam National University School of Medicine, Daejeon, South Korea (Y.-S.K.); GlaxoSmithKline (S.L.F.) and ViiV Healthcare (C.L.T., P.P., J.M., C.M.H., K.J.H., D.A.M., K.Y.S., W.R.S.) - both in Research Triangle Park, NC; ViiV Healthcare, Brentford, United Kingdom (V.C.); and Janssen Research and Development, Beerse, Belgium (H.C., W.P., S.V., P.E.W.).

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http://dx.doi.org/10.1056/NEJMoa1904398DOI Listing
March 2020

GENOMIC CHARACTERISATION AND PHYLOGENETIC ANALYSIS OF SARS-COV-2 IN ITALY.

J Med Virol 2020 Mar 29. Epub 2020 Mar 29.

Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1002/jmv.25794DOI Listing
March 2020

Pharmacokinetic drug evaluation of ritonavir (versus cobicistat) as adjunctive therapy in the treatment of HIV.

Expert Opin Drug Metab Toxicol 2019 Nov 3;15(11):927-935. Epub 2019 Nov 3.

Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1080/17425255.2019.1685495DOI Listing
November 2019

Response to letter to the editor: switch to dolutegravir and unboosted atazanavir.

AIDS 2019 11;33(14):2263-2264

Department of Infectious Diseases, Sacco Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/QAD.0000000000002330DOI Listing
November 2019

Is there a role for procalcitonin determination in avoiding unnecessary exposure to antibiotics in a non-intensive care setting?

Infez Med 2019 Jun;27(2):128-133

III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milano, Italy;Department of Biomedical and Clinical Sciences "Luigi Sacco", Universita degli Studi di Milano, Italy.

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June 2019

Choosing appropriate pharmacotherapy for drug-resistant HIV.

Expert Opin Pharmacother 2019 Apr 24;20(6):667-678. Epub 2019 Jan 24.

a Divisione Malattie Infettive , Aziende Socio Sanitarie Territoriale Fatebenefratelli Sacco , Milano , Italy.

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http://dx.doi.org/10.1080/14656566.2019.1570131DOI Listing
April 2019

Drug-drug interactions of a two-drug regimen of dolutegravir and lamivudine for HIV treatment.

Expert Opin Drug Metab Toxicol 2019 Mar 11;15(3):245-252. Epub 2019 Feb 11.

b Department of Infectious Diseases , ASST Fatebenefratelli Sacco University Hospital , Milan , Italy.

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http://dx.doi.org/10.1080/17425255.2019.1577821DOI Listing
March 2019

The contribution of immune activation and accelerated aging in multiple myeloma occurring in HIV-infected population.

AIDS 2018 11;32(18):2841-2846

Department of Physiopathology Medical-Surgery and Transplantation, University of Milan.

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http://dx.doi.org/10.1097/QAD.0000000000002015DOI Listing
November 2018

A three-in-one, long-acting, nanosuspension reformulation of off-patent antiretrovirals for low-income and middle-income countries.

AIDS 2018 11;32(17):2625-2627

Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/QAD.0000000000001970DOI Listing
November 2018

What is new in infectious diseases: Nipah virus, MERS-CoV and the Blueprint List of the World Health Organization.

Infez Med 2018 Sep;26(3):195-198

Direzione Strategica ASST Fatebenefratelli Sacco, Milano, Italy.

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September 2018

Seroconversion on preexposure prophylaxis.

AIDS 2018 06;32(9):1199-1200

Division of Hospital Medicine.

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http://dx.doi.org/10.1097/QAD.0000000000001826DOI Listing
June 2018

Dolutegravir and metformin: a clinically relevant or just a pharmacokinetic interaction?

AIDS 2018 02;32(4):532-533

Gestione Ambulatoriale Politerapie (GAP) Outpatient Clinic, ASST Fatebenefratelli Sacco.

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http://dx.doi.org/10.1097/QAD.0000000000001720DOI Listing
February 2018

Psychoactive drugs and HIV: are we sure to treat our patients adequately?

AIDS 2018 01;32(1):127-128

Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/QAD.0000000000001656DOI Listing
January 2018

Dolutegravir plus rilpivirine dual therapy in treating HIV-1 infection.

Expert Opin Pharmacother 2018 Jan 22;19(1):65-77. Epub 2017 Dec 22.

a First Division of Infectious Diseases , ASST Fatebenefratelli-Sacco , Milano , Italy.

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http://dx.doi.org/10.1080/14656566.2017.1417984DOI Listing
January 2018

Brief Report: Drop in CD4+ Counts Below 200 Cells/μL After Reaching (or Starting From) Values Higher than 350 Cells/μL in HIV-Infected Patients With Virological Suppression.

J Acquir Immune Defic Syndr 2017 12;76(4):417-422

*Malattie Infettive, IRCCS San Raffaele, Milano, Italy; †Dipartimento di Scienze della Salute, Clinica Malattie Infettive e Tropicali, ASST Santi Paolo e Carlo, Milano, Italy; ‡Area Dipartimentale HIV/AIDS, Istituto Nazionale per le Malattie Infettive L. Spallanzani IRCCS, Roma, Italy; §Clinic of Infectious Diseases, Univesity of Bari, Bari, Italy; ‖Clinic of Infectious Diseases, "San Gerardo" Hospital-ASST Monza, University Milano-Bicocca, Milano, Italy; ¶Malattie Infettive, ASST Fatebenefratelli Sacco, Milano, Italy; #Department of Public Health and Infectious Disease, Malattie Infettive, Sapienza University of Rome, polo Pontino, Roma, Italy; **Malattie Infettive, Università degli Studi, Policlinico di Modena, Modena, Italy; ††Unitá di Epidemiologia Clinica, Istituto Nazionale per le Malattie Infettive L. Spallanzani IRCCS, Roma, Italy; and ‡‡Infection and Population Health, Institute of Global Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1097/QAI.0000000000001522DOI Listing
December 2017

Pharmacokinetic drug evaluation of dolutegravir plus rilpivirine for the treatment of HIV.

Expert Opin Drug Metab Toxicol 2017 Nov 30;13(11):1183-1192. Epub 2017 Aug 30.

a 1st Division of Infectious Diseases , ASST Fatebenefratelli-Sacco , Milano , Italy.

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https://www.tandfonline.com/doi/full/10.1080/17425255.2017.1
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http://dx.doi.org/10.1080/17425255.2017.1361929DOI Listing
November 2017

Effects of ritonavir and cobicistat on dolutegravir exposure: when the booster can make the difference.

J Antimicrob Chemother 2017 06;72(6):1842-1844

Unit of Clinical Pharmacology, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1093/jac/dkx055DOI Listing
June 2017

How Relevant is the Interaction Between Dolutegravir and Metformin in Real Life?

J Acquir Immune Defic Syndr 2017 05;75(1):e24-e26

*Department of Infectious Diseases, L. Sacco University Hospital, Milan, Italy †Clinical Pharmacology Unit, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università degli Studi di Milano, Milan, Italy ‡E. Medea Scientific Institute, Bosisio Parini, Italy §School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa ‖Unit of Clinical Pharmacology, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/QAI.0000000000001292DOI Listing
May 2017

Intolerance of dolutegravir-containing combination antiretroviral therapy: not just a pharmacokinetic drug interaction.

AIDS 2017 03;31(6):867-868

aUnit of Clinical Pharmacology bDepartment Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy cWhitwaterstrand University, Johannesburg, South Africa d3rd Division of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://Insights.ovid.com/crossref?an=00002030-201703270-0001
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http://dx.doi.org/10.1097/QAD.0000000000001394DOI Listing
March 2017

Strategies to limit immune-activation in HIV patients.

Expert Rev Anti Infect Ther 2017 01 4;15(1):43-54. Epub 2016 Nov 4.

d Department of Physiopathology and Transplants , University of Milano , Milano , Italy.

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http://dx.doi.org/10.1080/14787210.2017.1250624DOI Listing
January 2017

HCV novel therapeutic regimens in Wonderland: A budget impact analysis in the Lombardy Region.

Dig Liver Dis 2016 Oct 11;48(10):1200-7. Epub 2016 Jul 11.

Centre for Research on Health Economics, Social and Health Care Management, LIUC - Carlo Cattaneo University, Castellanza, Italy.

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http://dx.doi.org/10.1016/j.dld.2016.06.028DOI Listing
October 2016

Antiretroviral treatments' durability and costs: important elements in the choice of first-line therapy.

AIDS 2016 09;30(14):2247-9

aCentre for Research on Health Economics, Social and Healthcare Management (CREMS), LIUC - Università Cattaneo, Castellanza, Italy bSchool of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa cFirst and Second Divisions of Infectious Diseases, 'Luigi Sacco' Hospital, Milan, Italy dSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000001210DOI Listing
September 2016

Knowledge transfer: what drug information would specialist doctors need to support their clinical practice? Results of a survey and of three focus groups in Italy.

BMC Med Inform Decis Mak 2016 09 1;16:115. Epub 2016 Sep 1.

Laboratory of Citizen Involvement in Health Care, IRCCS Mario Negri Institute of Pharmacological Research, Milan, Italy.

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http://dx.doi.org/10.1186/s12911-016-0355-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007811PMC
September 2016

Darunavir/cobicistat for the treatment of HIV-1: a new era for compact drugs with high genetic barrier to resistance.

Expert Opin Pharmacother 2015 27;16(17):2689-702. Epub 2015 Nov 27.

a 1st Division of Infectious Diseases, Department of Infectious Diseases , Luigi Sacco University Hospital , GB Grassi 74, Milan 20157 , Italy.

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http://dx.doi.org/10.1517/14656566.2015.1109632DOI Listing
June 2016

Determinants of bone diseases in tenofovir-treated HIV patients.

AIDS 2016 06;30(10):1686-7

aDepartment of Infectious Diseases, Luigi Sacco University Hospital, Milan, Italy bUnit of Clinical Pharmacology, Luigi Sacco University Hospital, Milan, Italy cClinical Pharmacology Unit, CNR Institute of Neuroscience, Department Biomedical and Clinical Sciences, Luigi Sacco University Hospital, Università di Milano, Milan Italy dScientific Institute IRCCS E.Medea, Bosisio Parini, Italy eSchool of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000001094DOI Listing
June 2016

Maraviroc Reduces Arterial Stiffness in PI-Treated HIV-infected Patients.

Sci Rep 2016 06 29;6:28853. Epub 2016 Jun 29.

Chair of Immunology, Department of Biomedical and Clinical Sciences "L. Sacco", University of Milan, Milan, Italy.

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http://dx.doi.org/10.1038/srep28853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926207PMC
June 2016

Potential association between rosuvastatin use and high atazanavir trough concentrations in ritonavir-treated HIV-infected patients.

Antivir Ther 2015 3;20(4):449-51. Epub 2014 Oct 3.

Department of Infectious Diseases, Luigi Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.3851/IMP2872DOI Listing
April 2016

New perspectives on nanotechnology and antiretroviral drugs: a 'small' solution for a big promise in HIV treatment?

AIDS 2016 Mar;30(6):963-4

aDepartment of Biomedical and Clinical Sciences, 'Luigi Sacco Hospital', University of Milan bDepartment of Infectious Diseases, 'Luigi Sacco Hospital', Milan, Italy cSchool of Clinical Medicine, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000001026DOI Listing
March 2016

Discontinuation of Initial Antiretroviral Therapy in Clinical Practice: Moving Toward Individualized Therapy.

J Acquir Immune Defic Syndr 2016 Mar;71(3):263-71

*Infectious Diseases Unit, IRCCS AOU S. Martino-IST, National Institute for Cancer Research, Genoa, Italy;†Department of Infection and Population Health, Division of Population Health, UCL Medical School, Royal Free Campus, London, United Kingdom;‡Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy;§Clinic of Infectious Diseases, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy;‖Infectious Diseases Unit, Busto Arsizio Hospital, Busto Arsizio (VA), Italy;¶Infectious Diseases Unit, Siena University Hospital, Siena, Italy;#Department of Health Sciences, University of Ancona, Ancona, Italy;**Infectious Diseases Clinic, Policlinico of Modena, University of Modena and Reggio Emilia, Modena, Italy;††Infectious Diseases Unit, Sacco Hospital, Milan, Italy;‡‡Infectious Diseases Unit, Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy;§§National Institute for Infectious Diseases IRCCS L. Spallanzani, Rome, Italy; and‖‖Clinic of Infectious and Tropical Diseases, Department of Health Sciences, S Paolo Hospital, University of Milan, Milan, Italy.

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http://pdfs.journals.lww.com/jaids/9000/00000/Discontinuatio
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAI.0000000000000849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770376PMC
March 2016

Managing hepatitis C virus-HIV liver transplant recipients with the new direct-acting antivirals: are we glimpsing a brilliant future behind our shoulders?

AIDS 2016 Jan;30(2):323-5

aDepartment of Gastroenterology, Hepatology and Liver Transplantation, Papa Giovanni XXIII Hospital, Bergamo bDepartment of Infectious Diseases, Niguarda Cà Granda Hospital cDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy dSchool of Clinical Medicine, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000000891DOI Listing
January 2016

Nanoformulation of antiretroviral drugs enhances their penetration across the blood brain barrier in mice.

Nanomedicine 2015 Aug 1;11(6):1387-97. Epub 2015 Apr 1.

Dipartimento di Scienze Biomediche e Cliniche "Luigi Sacco", Università di Milano, Milano, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15499634150008
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http://dx.doi.org/10.1016/j.nano.2015.03.009DOI Listing
August 2015

Simeprevir-induced severe withdrawal syndrome in an HIV/HCV coinfected patient on long-term maintenance methadone therapy.

Eur J Clin Pharmacol 2015 Aug 18;71(8):1027-8. Epub 2015 Jun 18.

Department of Infectious Diseases, Luigi Sacco University Hospital, Via GB Grassi 74, 20157, Milan, Italy,

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http://link.springer.com/10.1007/s00228-015-1890-3
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http://dx.doi.org/10.1007/s00228-015-1890-3DOI Listing
August 2015

Brief Report: Cobicistat Compared With Ritonavir as a Pharmacoenhancer for Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate: Week 144 Results.

J Acquir Immune Defic Syndr 2015 Jul;69(3):338-40

*Southwest CARE Center, Santa Fe, NM; †Inst. Dominicano de Estudios Virologicos, Santo Domingo, Dominican Republic; ‡HIV Unit, Hospital Civil de Guadalajara, Guadalajara, Mexico; §Department of Medicine, Khonkaen University, Khonkaen, Thailand; ‖Orlando Immunology Center, Orlando, FL; ¶Instituto de Saúde Ambiental, Faculdade de Medicina de Lisboa, Lisbon, Portugal; #EPIMED, Vivantes Auguste-Viktoria-Klinikum, Berlin, Germany; **Infectious Diseases Department, "Luigi Sacco" Hospital, Milan, Italy; ††Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; and ‡‡Gilead Sciences, Inc., Foster City, CA.

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http://dx.doi.org/10.1097/QAI.0000000000000598DOI Listing
July 2015

Comparison of the pharmacokinetics of raltegravir given at 2 doses of 400 mg by swallowing versus one dose of 800 mg by chewing in healthy volunteers: a randomized, open-label, 2-period, single-dose, crossover phase 1 study.

Ther Drug Monit 2015 Feb;37(1):119-25

*Unit of Clinical Pharmacology; †Department of Infectious Diseases; ‡Clinical Pharmacology Unit, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università degli Studi di Milano, Milan; §Scientific Institute E. Medea, Bosisio Parini, Italy; and ¶School of Clinical Medicine, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/FTD.0000000000000114DOI Listing
February 2015

Budget impact analysis of antiretroviral less drug regimen simplification in HIV-positive patients on the Italian National Health Service.

Clinicoecon Outcomes Res 2014 23;6:409-14. Epub 2014 Sep 23.

Department of Community Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa ; Centro di Ricerca in Economia e Management in Sanità e nel Sociale (CREMS), Università Carlo Cattaneo - LIUC, Castellanza (VA), Italy.

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http://dx.doi.org/10.2147/CEOR.S68101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181445PMC
October 2014

Health technology assessment in the HIV setting: the case of monotherapy.

New Microbiol 2014 Jul 1;37(3):247-61. Epub 2014 Jul 1.

CREMS (Centre for Research on Health Economics, Social and Health Care Management), Carlo Cattaneo University, LIUC, Castellanza (VA), Italy.

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July 2014

Cobicistat : a new opportunity in the treatment of HIV disease?

Expert Opin Pharmacother 2014 Jun 12;15(9):1289-98. Epub 2014 May 12.

Luigi Sacco Hospital, Department of Infectious Diseases , via GB Grassi 74, Milano, 20157 , Italy

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http://dx.doi.org/10.1517/14656566.2014.920008DOI Listing
June 2014

Profile of infective endocarditis observed from 2003 - 2010 in a single center in Italy.

BMC Infect Dis 2013 Nov 15;13:545. Epub 2013 Nov 15.

Department of Biomedical and Clinical Sciences "Luigi Sacco", Università di Milano, "Luigi Sacco" Hospital, via G, B, Grassi, 74, 20157 Milano, Italy.

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http://dx.doi.org/10.1186/1471-2334-13-545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225612PMC
November 2013

Economic evaluation of initial antiretroviral therapy for HIV-infected patients: an update of Italian guidelines.

Clinicoecon Outcomes Res 2013 Oct 3;5:489-96. Epub 2013 Oct 3.

Department of Drug Sciences, University of Pavia, Pavia, Italy ; SAVE - Studi Analisi Valutazioni Economiche, Milan, Italy.

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http://dx.doi.org/10.2147/CEOR.S48246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794870PMC
October 2013

Four years of immunization with OM-85 BV to prevent respiratory infections in HIV+ patients.

Hum Vaccin Immunother 2013 Sep 21;9(9):1849-51. Epub 2013 Jun 21.

1st Division of Infectious Diseases; "Luigi Sacco" University Hospital; Milan, Italy.

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http://dx.doi.org/10.4161/hv.25104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906347PMC
September 2013

The management of antiretroviral treatments in Europe: the Italian experience.

AIDS 2013 Sep;27(14):N3-6

aDepartment of Infectious Diseases, L. Sacco University Hospital, Milan bCREMS (Centre for Research on Health Economics, Social and Healthcare Management), University Carlo Cattaneo - LIUC, Castellanza, Varese, Italy cSchool of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000000004DOI Listing
September 2013

Linezolid plasma concentrations and occurrence of drug-related haematological toxicity in patients with gram-positive infections.

Int J Antimicrob Agents 2013 Jun 4;41(6):586-9. Epub 2013 Apr 4.

Unit of Clinical Pharmacology, Luigi Sacco University Hospital, Via G.B. Grassi 74, 20157 Milan, Italy.

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http://dx.doi.org/10.1016/j.ijantimicag.2013.02.020DOI Listing
June 2013