Publications by authors named "Giulia Rancati"

32Publications

P53 induces senescence in the unstable progeny of aneuploid cells.

Cell Cycle 2020 Dec 11;19(24):3508-3520. Epub 2020 Dec 11.

nstitute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.

View Article and Find Full Text PDF
December 2020

The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis.

Oncogene 2020 10 25;39(44):6816-6840. Epub 2020 Sep 25.

Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore, 138673, Republic of Singapore.

View Article and Find Full Text PDF
October 2020

A Chemically Defined Feeder-free System for the Establishment and Maintenance of the Human Naive Pluripotent State.

Stem Cell Reports 2019 10 12;13(4):612-626. Epub 2019 Sep 12.

Stem Cell and Regenerative Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore. Electronic address:

View Article and Find Full Text PDF
October 2019

The conditional nature of gene essentiality.

Curr Opin Genet Dev 2019 10 27;58-59:55-61. Epub 2019 Aug 27.

Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A⁎STAR), 8A Biomedical Grove, Immunos #05, Singapore 138648, Singapore. Electronic address:

View Article and Find Full Text PDF
October 2019

The Mutator Phenotype: Adapting Microbial Evolution to Cancer Biology.

Front Genet 2019 6;10:713. Epub 2019 Aug 6.

Institute of Medical Biology (IMB), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.

View Article and Find Full Text PDF
August 2019

Experimental evolution of a fungal pathogen into a gut symbiont.

Science 2018 11;362(6414):589-595

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.

View Article and Find Full Text PDF
November 2018

Environmental stresses induce karyotypic instability in colorectal cancer cells.

Mol Biol Cell 2019 01 31;30(1):42-55. Epub 2018 Oct 31.

Institute of Medical Biology, Singapore 138648, Republic of Singapore.

View Article and Find Full Text PDF
January 2019

Recruitment of the mitotic exit network to yeast centrosomes couples septin displacement to actomyosin constriction.

Nat Commun 2018 10 17;9(1):4308. Epub 2018 Oct 17.

Centre de Recherche en Biologie Cellulaire de Montpellier (CRBM), 1919 Route de Mende, 34293, Montpellier, France.

View Article and Find Full Text PDF
October 2018

Cancer: a CINful evolution.

Curr Opin Cell Biol 2018 06 3;52:136-144. Epub 2018 Apr 3.

Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore. Electronic address:

View Article and Find Full Text PDF
June 2018

Mammalian Cells Undergo Endoreduplication in Response to Lactic Acidosis.

Sci Rep 2018 02 13;8(1):2890. Epub 2018 Feb 13.

Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

View Article and Find Full Text PDF
February 2018

Emerging and evolving concepts in gene essentiality.

Nat Rev Genet 2018 Jan 16;19(1):34-49. Epub 2017 Oct 16.

Singapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Immunos #04, Singapore 138648, Singapore.

View Article and Find Full Text PDF
January 2018

Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells.

Stem Cell Reports 2017 06;8(6):1675-1688

Institute of Medical Biology, Agency for Science Technology and Research (A(∗)STAR), 8a Biomedical Grove, #06-06 Immunos, Singapore 138648, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore. Electronic address:

View Article and Find Full Text PDF
June 2017

Impairing Cohesin Smc1/3 Head Engagement Compensates for the Lack of Eco1 Function.

Structure 2016 11 29;24(11):1991-1999. Epub 2016 Sep 29.

Bioinformatics Institute (BII), Agency for Science, Technology and Research (A(∗)STAR), 138671 Singapore, Singapore; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A(∗)STAR), 138673 Singapore, Singapore; Department of Physics, National University of Singapore (NUS), 117551 Singapore, Singapore. Electronic address:

View Article and Find Full Text PDF
November 2016

Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53.

Mol Biol Cell 2016 10 24;27(20):3065-3084. Epub 2016 Aug 24.

Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

View Article and Find Full Text PDF
October 2016

Adaptive Evolution: Don't Fix What's Broken.

Curr Biol 2016 Feb;26(4):R169-71

Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore. Electronic address:

View Article and Find Full Text PDF
February 2016

Gene Essentiality Is a Quantitative Property Linked to Cellular Evolvability.

Cell 2015 Dec 25;163(6):1388-99. Epub 2015 Nov 25.

Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore. Electronic address:

View Article and Find Full Text PDF
December 2015