Giulia Casorati

Giulia Casorati

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Giulia Casorati

Giulia Casorati

Publications by authors named "Giulia Casorati"

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60Publications

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The Pathophysiological Relevance of the iNKT Cell/Mononuclear Phagocyte Crosstalk in Tissues.

Front Immunol 2018 12;9:2375. Epub 2018 Oct 12.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.3389/fimmu.2018.02375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194905PMC
October 2019

Potential advantages of CD1-restricted T cell immunotherapy in cancer.

Mol Immunol 2018 11 8;103:200-208. Epub 2018 Oct 8.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S01615890183083
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http://dx.doi.org/10.1016/j.molimm.2018.09.025DOI Listing
November 2018

Harnessing the CD1 restricted T cell response for leukemia adoptive immunotherapy.

Cytokine Growth Factor Rev 2017 08 8;36:117-123. Epub 2017 Jul 8.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, via Olgettina 58, 20132 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2017.06.007DOI Listing
August 2017

Of self-lipids, CD1-restricted T cells, and contact sensitization.

Eur J Immunol 2017 07;47(7):1119-1122

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1002/eji.201747112DOI Listing
July 2017

miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling.

Proc Natl Acad Sci U S A 2016 12 5;113(51):E8286-E8295. Epub 2016 Dec 5.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, 20132 Milan, Italy;

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http://dx.doi.org/10.1073/pnas.1612024114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187732PMC
December 2016

The circulating microRNome demonstrates distinct lymphocyte subset-dependent signatures.

Eur J Immunol 2016 Mar 29;46(3):725-31. Epub 2015 Dec 29.

Istituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi", Milan, Italy.

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http://dx.doi.org/10.1002/eji.201545787DOI Listing
March 2016

A Subset of CD8αβ+ Invariant NKT Cells in a Humanized Mouse Model.

J Immunol 2015 Aug 8;195(4):1459-69. Epub 2015 Jul 8.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033;

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http://dx.doi.org/10.4049/jimmunol.1500574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530047PMC
August 2015

Targeting leukemia by CD1c-restricted T cells specific for a novel lipid antigen.

Oncoimmunology 2015 Mar 3;4(3):e970463. Epub 2014 Dec 3.

Experimental Immunology Unit; Division of Immunology, Transplantation and Infectious Diseases; San Raffaele Scientific Institute ; Milano, Italy.

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http://dx.doi.org/10.4161/21624011.2014.970463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404883PMC
March 2015

Somatically mutated tumor antigens in the quest for a more efficacious patient-oriented immunotherapy of cancer.

Cancer Immunol Immunother 2015 Jan 28;64(1):99-104. Epub 2014 Aug 28.

Biocenter, Division for Bioinformatics, Innsbruck Medical University, Innrain 80, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00262-014-1599-7DOI Listing
January 2015

iNKT-cell help to B cells: a cooperative job between innate and adaptive immune responses.

Eur J Immunol 2014 Aug 30;44(8):2230-7. Epub 2014 May 30.

Experimental Immunology Unit, Division of Immunology Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1002/eji.201344399DOI Listing
August 2014

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias.

J Exp Med 2014 Jun 16;211(7):1363-77. Epub 2014 Jun 16.

Experimental Immunology, Department of Biomedicine, University Hospital Basel; Nuclear Magnetic Resonance Laboratory, Department of Chemistry; and Department of Biochemistry, Biozentrum; University of Basel, 4056 Basel, Switzerland Singapore Immunology Network (SIgN), Agency for Science, Technology, and Research, Singapore 138648

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http://jem.rupress.org/content/211/7/1363.full.pdf
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http://www.jem.org/lookup/doi/10.1084/jem.20140410
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http://dx.doi.org/10.1084/jem.20140410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076585PMC
June 2014

Functional education of invariant NKT cells by dendritic cell tuning of SHP-1.

J Immunol 2013 Apr 20;190(7):3299-308. Epub 2013 Feb 20.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, 20132 Milano, Italy.

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http://dx.doi.org/10.4049/jimmunol.1203466DOI Listing
April 2013

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer.

Nat Med 2012 May;18(5):807-815

Experimental Hematology Unit, Division of Regenerative Medicine, Gene Therapy and Stem Cells, Program of Immunology, Gene Therapy and Bio-Immunotherapy of Cancer, Leukemia Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1038/nm.2700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019824PMC
May 2012

Invariant natural killer T cells reconstitution and the control of leukemia relapse in pediatric haploidentical hematopoietic stem cell transplantation.

Oncoimmunology 2012 May;1(3):355-357

Experimental immunology Unit; Division of Immunology; Transplantation and Infectious Diseases; San Raffaele Scientific Institute; Milano, Italy.

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http://dx.doi.org/10.4161/onci.18399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382855PMC
May 2012

Follicular helper NKT cells induce limited B cell responses and germinal center formation in the absence of CD4(+) T cell help.

J Immunol 2012 Apr 29;188(7):3217-22. Epub 2012 Feb 29.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, 20132 Milan, Italy.

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http://dx.doi.org/10.4049/jimmunol.1103501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559029PMC
April 2012

On the use of donor-derived iNKT cells for adoptive immunotherapy to prevent leukemia recurrence in pediatric recipients of HLA haploidentical HSCT for hematological malignancies.

Clin Immunol 2011 Aug 24;140(2):152-9. Epub 2010 Dec 24.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1016/j.clim.2010.11.015DOI Listing
August 2011

An unexpected requirement for CD4+ T cells in anti-glycolipid antibody responses.

Immunol Cell Biol 2011 May 12;89(4):499-501. Epub 2011 Apr 12.

Division of Immunology, Experimental Immunology Unit, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.

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http://dx.doi.org/10.1038/icb.2011.21DOI Listing
May 2011

High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells.

Eur J Immunol 2011 Mar 18;41(3):602-10. Epub 2011 Jan 18.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, DIBIT, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1002/eji.201041211DOI Listing
March 2011

An efficient strategy to induce and maintain in vitro human T cells specific for autologous non-small cell lung carcinoma.

PLoS One 2010 Aug 9;5(8):e12014. Epub 2010 Aug 9.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012014PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918513PMC
August 2010

The CD4+ T-cell epitope-binding register is a critical parameter when generating functional HLA-DR tetramers with promiscuous peptides.

Eur J Immunol 2010 Jun;40(6):1603-16

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1002/eji.200940123DOI Listing
June 2010

iNKT cells control mouse spontaneous carcinoma independently of tumor-specific cytotoxic T cells.

PLoS One 2010 Jan 13;5(1):e8646. Epub 2010 Jan 13.

Cellular Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, Istituto Scientifico San Raffaele, Milan, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008646PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800182PMC
January 2010

Invariant TCR rather than CD1d shapes the preferential activities of C-glycoside analogues against human versus murine invariant NKT cells.

J Immunol 2009 Oct 4;183(7):4415-21. Epub 2009 Sep 4.

HIV and Malaria Vaccine Program, Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA.

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http://dx.doi.org/10.4049/jimmunol.0901021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603359PMC
October 2009

Dicer-dependent microRNA pathway controls invariant NKT cell development.

J Immunol 2009 Aug 22;183(4):2506-12. Epub 2009 Jul 22.

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, H San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.4049/jimmunol.0901361DOI Listing
August 2009

B cell helper assays.

Methods Mol Biol 2009 ;514:15-26

Istituto Nazionale di Genetica Molecolare-INGM, Milan, Italy.

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http://dx.doi.org/10.1007/978-1-60327-527-9_2DOI Listing
March 2009

NKT-cell help to B lymphocytes can occur independently of cognate interaction.

Blood 2009 Jan 2;113(2):370-6. Epub 2008 Oct 2.

Experimental Immunology Unit, Cancer Immunotherapy and Gene Therapy Program, DIBIT, H. San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1182/blood-2008-06-166249DOI Listing
January 2009

Use of MHC class II tetramers to investigate CD4+ T cell responses: problems and solutions.

Cytometry A 2008 Nov;73(11):1010-8

Experimental Immunology Unit, Cancer Immunotherapy and Gene Therapy Program, DIBIT, San Raffaele Scientific Institute, Milan 20132, Italy.

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http://dx.doi.org/10.1002/cyto.a.20603DOI Listing
November 2008

Innate-like effector differentiation of human invariant NKT cells driven by IL-7.

J Immunol 2008 Apr;180(7):4415-24

Experimental Immunology Unit, Cancer Immunotherapy and Gene Therapy Program, DIBIT, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.4049/jimmunol.180.7.4415DOI Listing
April 2008

MAGE-A3(161-175) contains an HLA-DRbeta4 restricted natural epitope poorly formed through indirect presentation by dendritic cells.

Cancer Immunol Immunother 2008 Feb 13;57(2):207-15. Epub 2007 Jul 13.

Tumor Immunology Unit, DIBIT, Scientific Institute H. San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1007/s00262-007-0364-6DOI Listing
February 2008

Emergence of antitumor cytolytic T cells is associated with maintenance of hematologic remission in children with acute myeloid leukemia.

Blood 2006 Dec 25;108(12):3843-50. Epub 2006 Jul 25.

Dipartimento di Scienze Pediatriche, Università di Pavia, IRCCS Policlinico San Matteo, P.le Golgi 2, 27100 Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2006-05-021535DOI Listing
December 2006

Peptidome from renal cell carcinoma contains antigens recognized by CD4+ T cells and shared among tumors of different histology.

Clin Cancer Res 2006 Aug;12(16):4949-57

Tumor Immunology Unit, DIBIT, Department of Oncology, Scientific Institute H. San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0995DOI Listing
August 2006

Cutting edge: influence of the TCR Vbeta domain on the selection of semi-invariant NKT cells by endogenous ligands.

J Immunol 2006 Feb;176(4):2064-8

Ludwig Institute for Cancer Research, Epalinges, Switzerland.

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http://dx.doi.org/10.4049/jimmunol.176.4.2064DOI Listing
February 2006

Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen- or tumour-derived synthetic peptides.

BMC Immunol 2005 Dec 5;6:24. Epub 2005 Dec 5.

Cancer Immunotherapy and Gene Therapy Program, Dept. of Oncology, DIBIT San Raffaele Scientific Institute, 20132 Milan, Italy.

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http://dx.doi.org/10.1186/1471-2172-6-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325046PMC
December 2005

Up-regulation of CD1d expression restores the immunoregulatory function of NKT cells and prevents autoimmune diabetes in nonobese diabetic mice.

J Immunol 2004 May;172(10):5908-16

Immunology of Diabetes and Islet Transplantation Program, Immunohistochemistry of Rodents Unit, H. San Raffaele Research Institute, Milan, Italy.

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http://dx.doi.org/10.4049/jimmunol.172.10.5908DOI Listing
May 2004

Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved.

Proc Natl Acad Sci U S A 2004 Jan 13;101(4):1022-6. Epub 2004 Jan 13.

Departments of Microbiology and Immunology, Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1073/pnas.0307847100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327144PMC
January 2004

CD4(+) T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope.

Cancer Res 2003 Dec;63(23):8481-6

Experimental Immunology Unit, Cancer Immunotherapy and Gene Therapy Program, Scientific Institute H. San Raffaele, 20132 Milan, Italy.

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December 2003

Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma.

Eur J Immunol 2003 Jul;33(7):1830-8

Neuroimmunology Unit-DIBIT, Department of Neurology, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1002/eji.200323885DOI Listing
July 2003

Innate immune responses support adaptive immunity: NKT cells induce B cell activation.

Vaccine 2003 Jun;21 Suppl 2:S48-54

IRIS Research Center, Chiron Vaccines, Via Fiorentina 1, I-53100 Siena, Italy.

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http://dx.doi.org/10.1016/s0264-410x(03)00200-7DOI Listing
June 2003