Giovanni Monteleone

Giovanni Monteleone

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Giovanni Monteleone

Publications by authors named "Giovanni Monteleone"

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Effect of chemical modulation of toll-like receptor 4 in an animal model of ulcerative colitis.

Eur J Clin Pharmacol 2020 Mar 25;76(3):409-418. Epub 2020 Jan 25.

Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Via Montpellier, 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00228-019-02799-7DOI Listing
March 2020

Correction: PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability.

Mod Pathol 2020 Mar 4. Epub 2020 Mar 4.

Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.

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http://dx.doi.org/10.1038/s41379-020-0512-5DOI Listing
March 2020

Impact of surgery on quality of life in Crohn's disease: short- and mid-term follow-up.

Updates Surg 2020 Mar 17. Epub 2020 Mar 17.

Gastrointestinal Surgery Unit, Tor Vergata University Hospital, Viale Oxford 81, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s13304-020-00738-1DOI Listing
March 2020

TGF-β activity restoration and phosphodiesterase 4 inhibition as therapeutic options for inflammatory bowel diseases.

Pharmacol Res 2020 Mar 16;155:104757. Epub 2020 Mar 16.

Chair of Gastroenterology, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy; Gastroenterology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2020.104757DOI Listing
March 2020

Are patients with inflammatory bowel disease at increased risk for Covid-19 infection?

J Crohns Colitis 2020 Mar 26. Epub 2020 Mar 26.

Gastrointestinal Unit, ASST-Fatebenefratelli Sacco - Department of Biochemical and Clinical Sciences "L. Sacco"- University of Milan, Italy.

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http://dx.doi.org/10.1093/ecco-jcc/jjaa061DOI Listing
March 2020

Contrast-enhanced endoscopic ultrasound diagnosis of the intraductal papillary mucinous neoplasm.

Clin J Gastroenterol 2020 Feb 6;13(1):120-126. Epub 2019 Jul 6.

Gastroenterology Unit, Department of Systems Medicine, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s12328-019-01008-3DOI Listing
February 2020

PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability.

Mod Pathol 2020 Feb 17. Epub 2020 Feb 17.

Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, Pavia, Italy.

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http://dx.doi.org/10.1038/s41379-020-0497-0DOI Listing
February 2020

Minimal Open Access Ileocolic Resection in Complicated Crohn's Disease of the Terminal Ileum.

Gastroenterol Res Pract 2020 28;2020:6019435. Epub 2020 Feb 28.

Department of Surgery "Pietro Valdoni", Sapienza University of Rome, Umberto I Hospital-Via Lancisi 2, 00155 Rome, Italy.

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http://dx.doi.org/10.1155/2020/6019435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064858PMC
February 2020

Interrogating host immunity to predict treatment response in inflammatory bowel disease.

Nat Rev Gastroenterol Hepatol 2020 Jan 25;17(1):9-20. Epub 2019 Nov 25.

School of Immunology and Microbial Sciences, King's College London, London, UK.

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http://dx.doi.org/10.1038/s41575-019-0228-5DOI Listing
January 2020

Role of Interleukin-34 in Cancer.

Cancers (Basel) 2020 Jan 20;12(1). Epub 2020 Jan 20.

Department of Systems Medicine, University of Rome "TOR VERGATA", 00133 Rome, Italy.

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http://dx.doi.org/10.3390/cancers12010252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017118PMC
January 2020

Idiopathic acute pancreatitis: a review on etiology and diagnostic work-up.

Clin J Gastroenterol 2019 Dec 30;12(6):511-524. Epub 2019 Apr 30.

Gastroenterology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://link.springer.com/10.1007/s12328-019-00987-7
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http://dx.doi.org/10.1007/s12328-019-00987-7DOI Listing
December 2019

Response Assessed by Ultrasonography as Target of Biological Treatment for Crohn's Disease.

Clin Gastroenterol Hepatol 2019 Dec 20. Epub 2019 Dec 20.

Gastroenterology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.10.042DOI Listing
December 2019

Inflammatory cytokines: from discoveries to therapies in IBD.

Expert Opin Biol Ther 2019 11 8;19(11):1207-1217. Epub 2019 Aug 8.

Department of Systems Medicine, Gastroenterology, University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/14712598.2019.1652267DOI Listing
November 2019

Exploring the genetic diversity of the 16S rRNA gene of in IBD and IBS.

Future Microbiol 2019 11 18;14:1497-1509. Epub 2019 Dec 18.

Unit of Medical Statistics & Molecular Epidemiology, University Campus Bio-Medico, Rome, Italy.

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http://dx.doi.org/10.2217/fmb-2019-0175DOI Listing
November 2019

Impact of Food Additives on Gut Homeostasis.

Nutrients 2019 Oct 1;11(10). Epub 2019 Oct 1.

Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/nu11102334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835893PMC
October 2019

Smad7 and Colorectal Carcinogenesis: A Double-Edged Sword.

Cancers (Basel) 2019 May 1;11(5). Epub 2019 May 1.

Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.3390/cancers11050612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563107PMC
May 2019

Oligonucleotides-A Novel Promising Therapeutic Option for IBD.

Front Pharmacol 2019 24;10:314. Epub 2019 Apr 24.

Department of Medicine 1, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

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https://www.frontiersin.org/article/10.3389/fphar.2019.00314
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http://dx.doi.org/10.3389/fphar.2019.00314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491809PMC
April 2019

Antisense Oligonucleotide: Basic Concepts and Therapeutic Application in Inflammatory Bowel Disease.

Front Pharmacol 2019 29;10:305. Epub 2019 Mar 29.

Department of Systems Medicine, Gastroenterology, University of Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.3389/fphar.2019.00305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450224PMC
March 2019

Targeting IL-23 in Crohn's disease.

Expert Rev Clin Immunol 2018 11 24;14(11):907-913. Epub 2018 Sep 24.

a Department of Systems Medicine , University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/1744666X.2018.1524754DOI Listing
November 2018

Advances in understanding the role of cytokines in inflammatory bowel disease.

Expert Rev Gastroenterol Hepatol 2018 Sep 30;12(9):907-915. Epub 2018 Jul 30.

a Department of Systems Medicine , University of Rome Tor Vergata , Italy.

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http://dx.doi.org/10.1080/17474124.2018.1503053DOI Listing
September 2018

Inflammatory bowel disease: new therapies from antisense oligonucleotides.

Ann Med 2018 08 21;50(5):361-370. Epub 2018 Jul 21.

a Department of Systems Medicine , University of Rome Tor Vergata , Rome, Italy.

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http://dx.doi.org/10.1080/07853890.2018.1490025DOI Listing
August 2018

Oligonucleotide-Based Therapies for Inflammatory Bowel Disease.

BioDrugs 2018 Aug;32(4):331-338

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.

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http://link.springer.com/10.1007/s40259-018-0286-1
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http://dx.doi.org/10.1007/s40259-018-0286-1DOI Listing
August 2018

Internal shoulder impingement in overhead athletes: an ultrasound imaging proposal.

Ultrasonography 2018 Jul 17;37(3):275-276. Epub 2018 Mar 17.

Department of Physical Medicine and Rehabilitation, University Rey Juan Carlos, Madrid.

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http://dx.doi.org/10.14366/usg.18008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044220PMC
July 2018

STAT3 Interactors as Potential Therapeutic Targets for Cancer Treatment.

Int J Mol Sci 2018 Jun 16;19(6). Epub 2018 Jun 16.

Department of Systems Medicine, University of Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.3390/ijms19061787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032216PMC
June 2018

Transforming Growth Factor-β1/Smad7 in Intestinal Immunity, Inflammation, and Cancer.

Front Immunol 2018 20;9:1407. Epub 2018 Jun 20.

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.3389/fimmu.2018.01407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019438PMC
June 2018

Radioguided Occult Lesion Localization in Deep Schwannomas of the Peripheral Nerves: Results of a Preliminary Case Series.

Acta Neurochir Suppl 2017 ;124:315-318

Neurosurgery Unit, Dell'Angelo Hospital, Via Paccagnella 11, Mestre-Venezia, 30172, Italy.

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http://dx.doi.org/10.1007/978-3-319-39546-3_46DOI Listing
November 2017

Immunomodulatory properties of Olea europaea leaf extract in intestinal inflammation.

Mol Nutr Food Res 2017 10 29;61(10). Epub 2017 Aug 29.

CIBER-EHD, Department of Pharmacology, ibs.GRANADA, Center for Biomedical Research (CIBM), University of Granada, Granada, Spain.

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http://dx.doi.org/10.1002/mnfr.201601066DOI Listing
October 2017

Update on the Therapeutic Efficacy of Tregs in IBD: Thumbs up or Thumbs down?

Inflamm Bowel Dis 2017 10;23(10):1682-1688

Department of Systems Medicine, University of Rome "Tor Vergata," Rome, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000001272DOI Listing
October 2017

The safety of non-biological treatments in Ulcerative Colitis.

Expert Opin Drug Saf 2017 Jul 19;16(7):779-789. Epub 2017 Jun 19.

a Department of Systems Medicine , University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/14740338.2017.1340936DOI Listing
July 2017

Evidence of IL-17 producing innate lymphoid cells in peripheral blood from patients with enteropathic spondyloarthritis.

Clin Exp Rheumatol 2016 Nov-Dec;34(6):1085-1093. Epub 2016 Oct 21.

Gastrointestinal Unit, Department of Medicina dei Sistemi, University of Rome Tor Vergata, Rome, Italy.

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June 2017

Sodium chloride-enriched Diet Enhanced Inflammatory Cytokine Production and Exacerbated Experimental Colitis in Mice.

J Crohns Colitis 2017 Feb 29;11(2):237-245. Epub 2016 Jul 29.

Cattedra di Gastroenterologia, Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1093/ecco-jcc/jjw139DOI Listing
February 2017

Therapy implications for the role of IL-21 in lupus.

Expert Rev Clin Immunol 2016 24;12(5):487-8. Epub 2016 Feb 24.

a Department of Systems Medicine , University of Rome Tor Vergata , Rome , Italy.

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http://dx.doi.org/10.1586/1744666X.2016.1152183DOI Listing
January 2017

Smad7 and its Potential as Therapeutic Target in Inflammatory Bowel Diseases.

Curr Drug Metab 2016 ;17(3):303-6

Department of Systems Medicine, University of Rome Tor Vergata, Italy.

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http://dx.doi.org/10.2174/1389200217666151210130103DOI Listing
November 2016

Sphingosine-1-phosphate receptor: a novel therapeutic target in ulcerative colitis.

Expert Rev Clin Immunol 2016 11 8;12(11):1137-1139. Epub 2016 Aug 8.

a Department of Systems Medicine , University of Rome 'Tor Vergata' , Rome , Italy.

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http://dx.doi.org/10.1080/1744666X.2016.1217774DOI Listing
November 2016

The gut-skin axis in health and disease: A paradigm with therapeutic implications.

Bioessays 2016 11 24;38(11):1167-1176. Epub 2016 Aug 24.

Dermatology Research Centre, Institute of Inflammation and Repair, University of Manchester and Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1002/bies.201600008DOI Listing
November 2016

Entrapment of the sciatic nerve at the linea aspera: A case report and literature review.

Surg Neurol Int 2016 19;7:89. Epub 2016 Oct 19.

Neurosurgery Unit, Dell'Angelo Hospital, Mestre (Ve), Italy.

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http://dx.doi.org/10.4103/2152-7806.192633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093878PMC
October 2016

Tofacitinib for the treatment of ulcerative colitis.

Expert Opin Investig Drugs 2016 Aug 30;25(8):991-7. Epub 2016 May 30.

a Department of Systems Medicine , University of Rome 'Tor Vergata' , Rome , Italy.

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http://dx.doi.org/10.1080/13543784.2016.1189900DOI Listing
August 2016

Mongersen, an oral Smad7 antisense oligonucleotide, in patients with active Crohn's disease.

Therap Adv Gastroenterol 2016 Jul 15;9(4):527-32. Epub 2016 Mar 15.

Department of Systems Medicine, University of Rome `Tor Vergata', Via Montpellier, 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1177/1756283X16636781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913329PMC
July 2016

Aryl hydrocarbon receptor-driven signals inhibit collagen synthesis in the gut.

Eur J Immunol 2016 Apr 5;46(4):1047-57. Epub 2016 Feb 5.

Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1002/eji.201445228DOI Listing
April 2016

The TGF-β/Smad System in IBD Pathogenesis.

Inflamm Bowel Dis 2015 Dec;21(12):2921-5

Department of Systems Medicine, University of Rome "Tor Vergata," Rome, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000000542DOI Listing
December 2015

Pathogenic aspects and therapeutic avenues of intestinal fibrosis in Crohn's disease.

Clin Sci (Lond) 2015 Dec;129(12):1107-13

Department of Systems Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy

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http://dx.doi.org/10.1042/CS20150472DOI Listing
December 2015

Reply: To PMID 25785968.

Gastroenterology 2015 Oct 28;149(4):1123. Epub 2015 Aug 28.

University of Rome, Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1053/j.gastro.2015.08.024DOI Listing
October 2015

Interleukin-34 sustains inflammatory pathways in the gut.

Clin Sci (Lond) 2015 Aug;129(3):271-80

*Department of Systems Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1042/CS20150132DOI Listing
August 2015

SILENT DELTOID ATROPHY IN BEACH VOLLEYBALL PLAYERS: A REPORT OF TWO CASES AND LITERATURE REVIEW.

Int J Sports Phys Ther 2015 Jun;10(3):347-53

School of Sport and Exercise Sciences, University of Rome "Tor Vergata", Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458922PMC
June 2015

Antisense approach to inflammatory bowel disease: prospects and challenges.

Drugs 2015 May;75(7):723-30

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.

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http://link.springer.com/10.1007/s40265-015-0391-0
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http://dx.doi.org/10.1007/s40265-015-0391-0DOI Listing
May 2015

Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease.

N Engl J Med 2015 Mar;372(12):1104-13

From the Department of Systems Medicine, University of Tor Vergata (G.M., M.C.F., S.O., L.B., F.P.), Gastroenterology Unit-Azienda Ospedaliera San Camillo-Forlanini (M.L.S.), Inflammatory Bowel Disease Unit, Complesso Integrato Columbus, Catholic University (A.A.), and Inflammatory Bowel Disease Unit, Department of Internal Medicine, Division of Gastroenterology, Sandro Pertini Hospital Rome (R.P.), Rome, Department of Surgery, L. Sacco University Hospital (S.A., M.F.), Department of Pathophysiology and Transplantation, University of Milan and Ospedale Policlinico di Milano (F. Caprioli), and Department of Biomedical Sciences for Health, University of Milan, and Gastroenterology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Policlinico San Donato, San Donato Milanese (M.V.), Milan, First Department of Internal Medicine, St. Matteo Hospital Foundation, University of Pavia, Pavia (A.D.S., G.R.C.), Gastroenterologia, Università Federico II di Napoli, Naples (F. Castiglione), Dipartimento di Scienze Chirurgiche Oncologiche e Gastroenterologiche-Unita' Operativa di Gastroenterologia-Universita' degli Studi di Padova, Padua (G.C.S.), Department of Medical and Surgical Specialties, Gastroenterology SOD2, Azienda Ospedaliero Universitaria Careggi, Florence (F.R.), Division of Gastroenterology, Casa Sollievo Sofferenza Hospital, IRCCS, San Giovanni Rotondo (F.B.), Department of Internal Medicine, Gastroenterology and Hepatology Unit, University of Genoa, Genoa (V.S.), and the Division of Internal Medicine Villa Sofia-Cervello Hospital, University of Palermo, Palermo (A.O.) - all in Italy; and the Department of Medicine, Medical Clinic 1, University of Erlangen-Nürnberg, Erlangen, Germany (M.F.N., R.A.).

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http://dx.doi.org/10.1056/NEJMoa1407250DOI Listing
March 2015

An overview of the role of innate lymphoid cells in gut infections and inflammation.

Mediators Inflamm 2014 1;2014:235460. Epub 2014 Jul 1.

Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://dx.doi.org/10.1155/2014/235460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100280PMC
February 2015

IL-21 as a therapeutic target in inflammatory disorders.

Expert Opin Ther Targets 2014 Nov 27;18(11):1329-38. Epub 2014 Aug 27.

University of Rome "Tor Vergata", Department of Systems Medicine , Rome , Italy +39 06 20903702 ; +39 06 72596391 ;

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http://www.tandfonline.com/doi/full/10.1517/14728222.2014.94
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http://dx.doi.org/10.1517/14728222.2014.945426DOI Listing
November 2014

Targeting integrins and adhesion molecules to combat inflammatory bowel disease.

Inflamm Bowel Dis 2014 Oct;20(10):1885-9

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000000091DOI Listing
October 2014

Proteinase activated-receptors-associated signaling in the control of gastric cancer.

World J Gastroenterol 2014 Sep;20(34):11977-84

Silvia Sedda, Irene Marafini, Roberta Caruso, Francesco Pallone, Giovanni Monteleone, Dipartimento di Medicina dei Sistemi, Università Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.3748/wjg.v20.i34.11977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161785PMC
September 2014

Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells.

Carcinogenesis 2014 Jul 30;35(7):1536-46. Epub 2014 Jan 30.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy, First Medical Clinic, University of Erlangen, Erlangen, Germany and Barts and the London School of Medicine and Dentistry, London, UK

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http://dx.doi.org/10.1093/carcin/bgu027DOI Listing
July 2014

Sampling of proximal and distal duodenal biopsies in the diagnosis and monitoring of celiac disease.

Dig Liver Dis 2014 Apr 4;46(4):323-9. Epub 2014 Jan 4.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2013.12.005DOI Listing
April 2014

Impairment of ghrelin synthesis in Helicobacter pylori-colonized stomach: new clues for the pathogenesis of H. pylori-related gastric inflammation.

World J Gastroenterol 2014 Jan;20(3):639-46

Omero Alessandro Paoluzi, Giovanna Del Vecchio Blanco, Roberta Caruso, Ivan Monteleone, Giovanni Monteleone, Francesco Pallone, Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921473PMC
http://dx.doi.org/10.3748/wjg.v20.i3.639DOI Listing
January 2014

Role of T17 cytokines in the control of colorectal cancer.

Oncoimmunology 2013 Dec 22;2(12):e26617. Epub 2013 Oct 22.

Department of Systems Medicine; University of Tor Vergata; Rome, Italy.

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http://www.tandfonline.com/doi/abs/10.4161/onci.26617
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http://dx.doi.org/10.4161/onci.26617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902118PMC
December 2013