Giovanni Coppola

Giovanni Coppola

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Giovanni Coppola

Publications by authors named "Giovanni Coppola"

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miRNA expression profiles and molecular networks in resting and LPS-activated BV-2 microglia-Effect of cannabinoids.

PLoS One 2019 11;14(2):e0212039. Epub 2019 Feb 11.

The Dr Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212039PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370221PMC
November 2019

Neurodegenerative Disease Caregivers' 5-HTTLPR Genotype Moderates the Effect of Patients' Empathic Accuracy Deficits on Caregivers' Well-Being.

Am J Geriatr Psychiatry 2019 Oct 29;27(10):1046-1056. Epub 2019 Apr 29.

Department of Psychology (JLW, CLB, AYH, PDS, K-HC, RWL), University of California, Berkeley, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2019.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739173PMC
October 2019

Astrocyte molecular signatures in Huntington's disease.

Sci Transl Med 2019 Oct;11(514)

Department of Physiology, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaw8546DOI Listing
October 2019

Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants.

Acta Neuropathol Commun 2019 Oct 22;7(1):159. Epub 2019 Oct 22.

Memory and Aging Center, Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s40478-019-0809-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805408PMC
October 2019

Gyrification abnormalities in presymptomatic expansion carriers.

J Neurol Neurosurg Psychiatry 2019 Sep 11;90(9):1005-1010. Epub 2019 May 11.

Neurology, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1136/jnnp-2018-320265DOI Listing
September 2019

A Rare Mutation of β-Adrenergic Receptor Affects Sleep/Wake Behaviors.

Neuron 2019 Sep 28;103(6):1044-1055.e7. Epub 2019 Aug 28.

Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94143, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763376PMC
September 2019

Historical Migration revealed through a Case of Autosomal Dominant Alzheimer's Disease.

P R Health Sci J 2019 Sep;38(3):144-147

Mary S. Easton for Alzheimer's Disease Research, UCLA, Los Angeles, CA; Department of Neurology, Keck School of Medicine of USC, Los Angeles, CA.

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September 2019

Longitudinal RNA-Seq analysis of acute and chronic neurogenic skeletal muscle atrophy.

Sci Data 2019 09 24;6(1):179. Epub 2019 Sep 24.

Department of Neurology, Neuromuscular Division, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1038/s41597-019-0185-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760191PMC
September 2019

Time Course of Changes in Peripheral Blood Gene Expression During Medication Treatment for Major Depressive Disorder.

Front Genet 2019 18;10:870. Epub 2019 Sep 18.

Neuromodulation Division, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.

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http://dx.doi.org/10.3389/fgene.2019.00870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760033PMC
September 2019

Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy.

Neuron 2019 Sep 18. Epub 2019 Sep 18.

University of California, San Francisco, Memory and Aging Center, Department of Neurology, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.08.037DOI Listing
September 2019

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.

Alzheimers Dement 2019 Jul 1. Epub 2019 Jul 1.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.04.007DOI Listing
July 2019

Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders.

Biol Psychiatry 2019 Jul 11. Epub 2019 Jul 11.

Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California; Department of Psychology, University of California, Los Angeles, Los Angeles, California; Brain Research Institute, University of California, Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.06.029DOI Listing
July 2019

Primary familial brain calcification caused by a novel homozygous MYORG mutation in a consanguineous Italian family.

Neurogenetics 2019 05 21;20(2):99-102. Epub 2019 Mar 21.

Department of Psychiatry, David Geffen School of Medicine, University of California Los Angeles, 695 Charles E. Young Drive South, #3506C Gonda Neuroscience and Genetics Research Center, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/s10048-019-00571-8DOI Listing
May 2019

Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in -ALS/FTD.

Proc Natl Acad Sci U S A 2019 May 24;116(19):9628-9633. Epub 2019 Apr 24.

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605;

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http://dx.doi.org/10.1073/pnas.1901313116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511021PMC
May 2019

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue.

Cell 2019 May 25;177(5):1280-1292.e20. Epub 2019 Apr 25.

Department of Physiology, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA; Department of Neurobiology, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526045PMC
May 2019

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimers Dement 2019 May 11. Epub 2019 May 11.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15525260193004
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http://dx.doi.org/10.1016/j.jalz.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842665PMC
May 2019

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

Am J Psychiatry 2019 Mar;176(3):217-227

The Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston (Yu, Illmann, Osiecki, Smoller, Pauls, Neale, Scharf); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass. (Yu, Neale, Scharf); the Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles (Sul, Huang, Zelaya, Ophoff, Freimer, Coppola); the Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (Sul, Huang, Zelaya, Freimer, Coppola); the Department of Molecular Biology and Genetics, Democritus University of Thrace, Xanthi, Greece (Tsetsos); the Department of Biological Sciences, Purdue University, West Lafayette, Ind. (Tsetsos, Paschou); deCODE Genetics/Amgen, Reykjavik, Iceland (Nawaz, H. Stefansson, K. Stefansson); the Bioinformatics Interdepartmental Program, University of California, Los Angeles (Huang, Zelaya); the Department of Psychiatry, University of California, San Francisco (Darrow); the Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco (Hirschtritt, Willsey); the Department of Psychiatry, Massachusetts General Hospital, Boston (Greenberg, Roffman, Buckner); the Clinic of Psychiatry, Social Psychiatry, and Psychotherapy, Hannover Medical School, Hannover, Germany (Muller-Vahl); the Institute of Human Genetics, Hannover Medical School, Hannover, Germany (Stuhrmann); McGill University Health Center, University of Montreal, McGill University Health Centre, Montreal (Dion); the Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal (Rouleau); the Department of Psychiatry and Psychotherapy, Medical University Vienna, Vienna (Aschauer, Stamenkovic); Biopsychosocial Corporation, Vienna (Aschauer, Schlögelhofer); University Health Network, Youthdale Treatment Centres, and University of Toronto, Toronto (Sandor); the Krembil Research Institute, University Health Network, Hospital for Sick Children, and University of Toronto, Toronto (Barr); Johns Hopkins University School of Medicine, Baltimore (Grados, Singer); the Institute of Human Genetics, University Hospital Bonn, University of Bonn Medical School, Bonn, Germany (Nöthen); the Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany (Hebebrand, Hinney); the Yale Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (King, Fernandez); the Institute of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest, Hungary (Barta); Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary (Tarnok, Nagy); the Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen, Essen, Germany (Depienne); Sorbonne Universités, UPMC Université Paris 06, UMR S 1127, CNRS UMR 7225, ICM, Paris (Depienne, Worbe, Hartmann); French Reference Centre for Gilles de la Tourette Syndrome, Groupe Hospitalier Pitié-Salpêtrière, Paris (Worbe, Hartmann); Assistance Publique-Hôpitaux de Paris, Department of Neurology, Groupe Hospitalier Pitié-Salpêtrière, Paris (Worbe, Hartmann); Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York (Budman); Child Neuropsychiatry, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy (Rizzo); the Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (Lyon); the Department of Psychiatry, University of Utah, Salt Lake City (McMahon); Children's Mercy Hospital, Kansas City, Mo. (Batterson); the Department of Psychiatry, University Medical Center Groningen and Rijksuniversity Groningen, and Drenthe Mental Health Center, Groningen, the Netherlands (Cath); the Department of Neurology, Fixel Center for Neurological Diseases, McKnight Brain Institute, University of Florida, Gainesville (Malaty, Okun); Pennsylvania State University College of Medicine, Hershey (Berlin); Marquette University and University of Wisconsin-Milwaukee, Milwaukee (Woods); Tripler Army Medical Center and University of Hawaii John A. Burns School of Medicine, Honolulu (Lee); Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston (Jankovic); the Division of Psychiatry, Department of Neuropsychiatry, University College London (Robertson); the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati (Gilbert); Children's Hospital of Philadelphia, Philadelphia (Brown); the Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami (Coffey); the Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (Dietrich, Hoekstra); University of Iowa Carver College of Medicine, Iowa City (Kuperman); the Department of Pediatrics, University of Washington, Seattle (Zinner); the Department of Pediatrics, Landspitalinn University Hospital, Reykjavik, Iceland (Luðvigsson, Thorarensen); the Faculty of Medicine, University of Iceland, Reykjavík, Iceland (Sæmundsen, Stefansson); the State Diagnostic and Counselling Centre, Kópavogur, Iceland (Sæmundsen); the Department of Genetics and the Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Atzmon, Barzilai); the Department of Human Biology, Haifa University, Haifa, Israel (Atzmon); the Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany (Wagner); the Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany (Moessner); SUNY Downstate Medical Center Brooklyn, New York (C.M. Pato, M.T. Pato, Knowles); the Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital, Charlestown (Roffman, Buckner); the Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston (Smoller); the Center for Brain Science and Department of Psychology, Harvard University, Cambridge, Mass. (Buckner); the Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco (Willsey); the Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway (Tischfield, Heiman); the Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, VU University Amsterdam, Amsterdam (Posthuma); the Division of Genetic Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tenn. (Cox, Davis); the Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston (Neale); the Department of Psychiatry, Genetics Institute, University of Florida, Gainesville (Mathews); and the Department of Neurology, Brigham and Women's Hospital, and the Department of Neurology, Massachusetts General Hospital, Boston (Scharf).

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http://dx.doi.org/10.1176/appi.ajp.2018.18070857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677250PMC
March 2019

A likely pathogenic variant in the gene presenting with progressive myoclonus.

Ann Clin Transl Neurol 2019 03 1;6(3):605-609. Epub 2019 Feb 1.

Center for Medical Genetics Ghent University Hospital Ghent Belgium.

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http://doi.wiley.com/10.1002/acn3.702
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http://dx.doi.org/10.1002/acn3.702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414494PMC
March 2019

Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers.

Neuroimage Clin 2019 16;22:101751. Epub 2019 Mar 16.

University of California, Memory and Aging Center, Department of Neurology, San Francisco, United States; University of California, Department of Pathology, San Francisco, United States.

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http://dx.doi.org/10.1016/j.nicl.2019.101751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438992PMC
March 2019

Regional association of pCASL-MRI with FDG-PET and PiB-PET in people at risk for autosomal dominant Alzheimer's disease.

Neuroimage Clin 2018 6;17:751-760. Epub 2017 Dec 6.

Laboratory of FMRI Technology (LOFT), USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842754PMC
February 2019

Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series.

J Neurol 2018 Dec 15;265(12):2960-2971. Epub 2018 Oct 15.

Department of Neurology, Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA.

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http://link.springer.com/10.1007/s00415-018-9086-2
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http://dx.doi.org/10.1007/s00415-018-9086-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245666PMC
December 2018

In the setting of β-cell stress, the pancreatic duct gland transcriptome shows characteristics of an activated regenerative response.

Am J Physiol Gastrointest Liver Physiol 2018 11 10;315(5):G848-G854. Epub 2018 Aug 10.

Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California Los Angeles , Los Angeles, California.

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http://dx.doi.org/10.1152/ajpgi.00177.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293255PMC
November 2018

Benign hereditary chorea and deletions outside NKX2-1: What's the role of MBIP?

Eur J Med Genet 2018 Oct 3;61(10):581-584. Epub 2018 Apr 3.

Molecular Neurogenetics, Foundation IRCCS Neurological Institute Besta, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmg.2018.03.011DOI Listing
October 2018

Generation and post-injury integration of human spinal cord neural stem cells.

Nat Methods 2018 09 6;15(9):723-731. Epub 2018 Aug 6.

Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41592-018-0074-3DOI Listing
September 2018

Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior.

Neuron 2018 09 30;99(6):1170-1187.e9. Epub 2018 Aug 30.

Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA; Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273183068
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http://dx.doi.org/10.1016/j.neuron.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450394PMC
September 2018

Bioinformatics and genomic databases.

Handb Clin Neurol 2018 ;147:75-92

Interdepartmental Program in Bioinformatics and Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-63233-3.00007-5DOI Listing
July 2018

Expanding the global prevalence of spinocerebellar ataxia type 42.

Neurol Genet 2018 Jun 5;4(3):e232. Epub 2018 Apr 5.

Department of Neurology (K.J.N., M.A., S.P., G.C., B.L.F.), Program in Neurogenetics, David Geffen School of Medicine, University of California, Los Angeles; Department of Medical Genetics (L.E.P., J.E.B.), Vanderbilt University Medical Center, Nashville, TN; Department of Psychiatry and Biobehavioral Sciences (J.A.C., G.C.), University of California, Los Angeles, CA; Institute of Neurological Sciences (F.C., S.C.), Italian National Research Council, Mangone, Italy; Department of Neurology (A.B.N., M.D.G.), UCSF Memory and Aging Center, University of California, San Francisco; Sackler Faculty of Medicine (S.H.), Tel-Aviv University, Israel; Italian College of General Practitioners and Primary Care (D.I.), Department of Clinical and Experimental Medicine (A.L.), University of Messina, Italy; and the Department of Human Genetics (B.L.F.), David Geffen School of Medicine, University of California, Los Angeles.

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http://dx.doi.org/10.1212/NXG.0000000000000232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886831PMC
June 2018

Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer's Disease.

J Alzheimers Dis 2017 ;58(4):1035-1041

Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.3233/JAD-161203DOI Listing
May 2018

Impairment of memory generalization in preclinical autosomal dominant Alzheimer's disease mutation carriers.

Neurobiol Aging 2018 05 8;65:149-157. Epub 2018 Feb 8.

Department of Neurology, UCLA, Los Angeles, CA, USA; Easton Center for Alzheimer's Disease Research, Los Angeles, CA, USA; Memory and Aging Center, Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871602PMC
May 2018

Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment.

Ann Clin Transl Neurol 2018 May 2;5(5):616-629. Epub 2018 Apr 2.

Department of Psychiatry Semel Institute for Neuroscience and Human Behavior University of California Los Angeles Los Angeles California.

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http://dx.doi.org/10.1002/acn3.560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945969PMC
May 2018

Microbiota effects on cancer: from risks to therapies.

Oncotarget 2018 Apr 3;9(25):17915-17927. Epub 2018 Apr 3.

S.S.D Sperimentazione Animale, Istituto Nazionale Tumori, IRCCS, "Fondazione G. Pascale", Naples, Italy.

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http://dx.doi.org/10.18632/oncotarget.24681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915165PMC
April 2018

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.

Neuron 2018 03;97(5):1032-1048.e5

Center for Neurobehavioral Genetics, The Jane and Terry Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927822PMC
March 2018

MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.

PLoS One 2018 11;13(1):e0190550. Epub 2018 Jan 11.

Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles (UCLA), Los Angeles, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764268PMC
February 2018

Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation.

Sci Rep 2017 12 12;7(1):17377. Epub 2017 Dec 12.

Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41598-017-17407-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727029PMC
December 2017

Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection.

Cell Rep 2017 Oct;21(2):517-532

Department of Neurobiology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Intellectual and Developmental Disabilities Research Center, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.09.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637483PMC
October 2017

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.

Neuron 2017 Aug 14;95(3):531-549.e9. Epub 2017 Jul 14.

Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA; Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811312PMC
August 2017

Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury.

Cell Rep 2017 08;20(5):1136-1147

Department of Molecular, Cellular, and Developmental Biology, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565222PMC
August 2017

Brain calcifications and variants.

Neurol Genet 2017 Aug 26;3(4):e166. Epub 2017 Jul 26.

Department of Genetics and CNR-MAJ (G.N., A.-C.R., O.Q.), Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Normandy Center for Genomic and Personalized Medicine, France; Department of Human Genetics (G.N.), Genome Research, Radboud UMC, Nijmegen, The Netherlands; Department of Neuroscience (M.S.-C., D.W.D., R.R.), Mayo Clinic, Jacksonville, FL; Department of Psychiatry (E.M.R., A.R.L., A.L., G.C., D.H.G.), Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles; Keizo Asami Laboratory (R.R.L., J.F., D.M., J.R.M.d.O), Federal University of Pernambuco, Recife, Brazil; Fundación Pública Galega de Medicina Xenómica (M.J.S.), Clinical University Hospital of Santiago de Compostela-SERGAS, Spain; Centre National de Recherche en Génomique Humaine (CNRGH) (J.-F.D., A.B.), Institut de Biologie François Jacob, CEA, Evry; Department of Neurology (P.K.), Amiens University Hospital; Department of Neurology (P.F.), Tenon Hospital, AP-HP, Paris, France; Medical Genetics MRI Unit (R.S., E.L.-L.), Shaare Zedek Medical Center; Hebrew University-Hadassah School of Medicine (R.S., E.L.-L.); and Neuropsychiatry Department (J.R.M.d.O), Universidade Federal de Pernambuco, Recife, Brazil.

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http://ng.neurology.org/lookup/doi/10.1212/NXG.0000000000000
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http://dx.doi.org/10.1212/NXG.0000000000000166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530423PMC
August 2017

Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.

Nat Commun 2017 08 21;8(1):300. Epub 2017 Aug 21.

Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA and Jonsson Comprehensive Cancer Center (JCCC), University of California Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1038/s41467-017-00346-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563506PMC
August 2017

Identification of an Efficient Gene Expression Panel for Glioblastoma Classification.

PLoS One 2016 17;11(11):e0164649. Epub 2016 Nov 17.

Semel Institute for Neuroscience & Human Behavior and Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California 90095, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164649PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113897PMC
June 2017

Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others.

Neuron 2017 Jun;94(6):1112-1120.e4

F.M. Kirby Neurobiology Center, Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273173047
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http://dx.doi.org/10.1016/j.neuron.2017.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519288PMC
June 2017

Genome-wide association study identifies locus influencing human plasma tau levels.

Neurology 2017 Feb 18;88(7):669-676. Epub 2017 Jan 18.

From the Department of Neurology (J.C., K.W., G.C.), David Geffen School of Medicine, and Memory and Aging Center (J.S.Y., J.H.K., H.R., B.L.M., A.L.B.), Department of Neurology, University of California, Los Angeles; Department of Neurology (J.-T.Y., H.-F.W.), Qingdao Municipal Hospital, Nanjing Medical University, China; Clinical Neurochemistry Laboratory (H.Z., K.B.), Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg Mölndal, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, London, UK; and Center for Imaging of Neurodegenerative Diseases (M.W.W.), VAMC San Francisco, CA.

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http://dx.doi.org/10.1212/WNL.0000000000003615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317386PMC
February 2017

Mapping Gene Expression in Excitatory Neurons during Hippocampal Late-Phase Long-Term Potentiation.

Front Mol Neurosci 2017 22;10:39. Epub 2017 Feb 22.

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los AngelesLos Angeles, CA, USA; Department of Biological Chemistry, University of California, Los AngelesLos Angeles, CA, USA.

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http://dx.doi.org/10.3389/fnmol.2017.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319997PMC
February 2017

ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60.

J Acquir Immune Defic Syndr 2016 Dec;73(4):426-432

*Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA; †Imaging Genetics Center, Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA; ‡Department of Epidemiology and Biostatistics, University of California, San Francisco, CA; and §Departments of Psychiatry and Neurology, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085854PMC
http://dx.doi.org/10.1097/QAI.0000000000001091DOI Listing
December 2016

Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.

Neurol Neuroimmunol Neuroinflamm 2016 Dec 28;3(6):e301. Epub 2016 Oct 28.

Memory and Aging Center (Z.A.M., V.E.S., A.K., J.S.Y., L.T.G., A.L.B., H.J.R., K.P.R., M.L.G.-T., W.W.S., B.L.M.) and Department of Pathology (L.T.G., W.W.S.), University of California, San Francisco; Departments of Neurology (G.B.C., N.R.G.-R.) and Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL; and Department of Neurology (G.C., D.H.G.), David Geffen School of Medicine, University of California, Los Angeles, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087253PMC
December 2016

New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo.

Neuron 2016 Dec 8;92(6):1181-1195. Epub 2016 Dec 8.

Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA; Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273163089
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http://dx.doi.org/10.1016/j.neuron.2016.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403514PMC
December 2016

Widespread white matter and conduction defects in PSEN1-related spastic paraparesis.

Neurobiol Aging 2016 11 8;47:201-209. Epub 2016 Aug 8.

Department of Neurology, Keck School of Medicine of USC Center for the Health Professionals, Los Angeles, CA, USA; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Mary S. Easton Center for Alzheimer's Disease Research, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075491PMC
http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.030DOI Listing
November 2016

Forward Genetic Screen in Suggests F57A10.2 and acp-4 As Suppressors of C9ORF72 Related Phenotypes.

Front Mol Neurosci 2016 8;9:113. Epub 2016 Nov 8.

Program for Neuropsychiatric Research, McLean Hospital and Harvard Medical School Belmont, MA, USA.

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http://dx.doi.org/10.3389/fnmol.2016.00113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100550PMC
November 2016

Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery.

Circ Cardiovasc Genet 2016 Oct 2;9(5):395-407. Epub 2016 Sep 2.

Cardiovascular Research Laboratory, University of California, Los Angeles, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085833PMC
http://dx.doi.org/10.1161/CIRCGENETICS.115.001363DOI Listing
October 2016

Design, Characterization, and Use of a Novel Amyloid β-Protein Control for Assembly, Neurotoxicity, and Gene Expression Studies.

Biochemistry 2016 09 29;55(36):5049-60. Epub 2016 Aug 29.

Department of Neurology, David Geffen School of Medicine at UCLA , Los Angeles, California 90095, United States.

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http://dx.doi.org/10.1021/acs.biochem.6b00579DOI Listing
September 2016

Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.

Acta Neuropathol Commun 2016 09 2;4(1):98. Epub 2016 Sep 2.

Memory and Aging Center, UCSF, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s40478-016-0367-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010724PMC
September 2016

Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.

Stem Cell Reports 2016 09 1;7(3):325-340. Epub 2016 Sep 1.

Department of Neurology, Chemical Neurobiology Laboratory, Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032560PMC
September 2016